m-Xylene
Empirical Formula (Hill Notation): | C8H10 |
Linear Formula: | C6H4(CH3)2 |
CAS Number: | 108-38-3 |
Molecular Weight: | 106.17 |
Beilstein/REAXYS Number: | 605441 |
EC Number: | 203-576-3 |
MDL number: | MFCD00008536 |
PubChem Substance ID: | 329823299 |
Кат. номер |
PHR1313-1G-PW |
PHR1313-1G |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
m-Xylene is widely used as a residual solvent (RS) or organic volatile impurity (OVI) in pharmaceutical formulations.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
m-Xylene may be used as a pharmaceutical reference standard for the determination of the analyte in tablet formulations by chromatography. It can also be used as a residual solvent standard for the quantification of the analyte in tablet formulations by headspace gas chromatography (HS-GC) with flame ionization detection (FID) technique.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAB3625 in the slot below. This is an example certificate only and may not be the lot that you receive.
grade | certified reference material, pharmaceutical secondary standard |
Quality Level | 300, |
vapor density | 3.7 (vs air) |
CofA | current certificate can be downloaded |
autoignition temp. | 982 °F |
feature | nist traceable 3004 |
expl. lim. | 7 % |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
refractive index | n20/D 1.497 (lit.) |
bp | 138-139 °C (lit.) |
mp | 48 °C (lit.) |
density | 0.868 g/mL at 25 °C (lit.) |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to USP 1601849 |
SMILES string | Cc1cccc(C)c1 |
InChI | 1S/C8H10/c1-7-4-3-5-8(2)6-7/h3-6H,1-2H3 |
InChI key | IVSZLXZYQVIEFR-UHFFFAOYSA-N |
pictograms | GHS02,GHS07,GHS08 |
signalword | Danger |
hcodes | H226 - H304 - H312 + H332 - H315 - H319 - H335 - H412 |
pcodes | P210 - P273 - P280 - P301 + P310 - P303 + P361 + P353 - P331 |
Target Organs | Respiratory system |
RIDADR | UN1307 - class 3 - PG 3 - Xylenes |
WGK Germany | WGK 2 |
Flash Point F | 80.6 °F - closed cup |
Flash Point C | 27 °C - closed cup |