Pharmaceuticals, Illicit Drugs & Diagnostic Biomarkers Sigma-Aldrich
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Sulfadiazine sodium salt
Empirical Formula (Hill Notation): C10H9N4NaO2S CAS Number: 547-32-0 Molecular Weight: 272.26 Beilstein/REAXYS Number: 4068213 EC Number: 208-919-0 MDL number: MFCD00067333 PubChem Substance ID: 329824562 NACRES: NA.24
Кат. номер S6387-100G S6387-VAR S6387-25G S6387-500G General descriptionSulfadiazine sodium salt is a broad-spectrum antibiotic belonging to the class of sulfonamides commonly used against gram-postive and gram-negative microorganisms in humans and veterinary medication. Its mode of action involves inhibiting the multiplication of bacteria as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle.ApplicationSulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.Packaging25, 100 g in glass bottleПараметрыgrade analytical standard Quality Level 100 assay 98% (HPLC) form crystalline powder application(s) HPLC: suitable, gas chromatography (GC): suitable Featured Industry Forensics and Toxicology
Pharmaceutical (small molecule)SMILES string Nc1ccc(cc1)S(=O)(=O)N([Na])c2ncccn2 InChI 1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1 InChI key JLDCNMJPBBKAHH-UHFFFAOYSA-N
Safety Informationpictograms GHS07,GHS09 signalword Warning hcodes H302 - H315 - H319 - H411 pcodes P273 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Sulfasalazine
Empirical Formula (Hill Notation): C18H14N4O5S CAS Number: 599-79-1 Molecular Weight: 398.39 Beilstein/REAXYS Number: 356241 EC Number: 209-974-3 MDL number: MFCD00057363 PubChem Substance ID: 329824182 NACRES: NA.24
Кат. номер S0883-100G S0883-VAR S0883-50G S0883-10G General descriptionChemical structure: sulfonamide
Sulfasalazine (SSZ) belongs to the sulfonamide class of drugs, which can be metabolized into 5-aminosalicylic acid and sulfapyridine. SSZ is obtained as a reaction product of an antibacterial agent (sulfapyridine) and an anti-inflammatory agent (salicylic acid).ApplicationRefer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfasalazine has been used as an analytical standard in clinical studies:- For investigating its therapeutic potential in patients suffering from multiple sclerosis (MS).
- For studying its role as an antiarthritic agent via inhibition of the cartilage degeneration and pain associated with progression of osteoarthritis in the rat, which is used as the test animal.
It may also be used as an analytical reference standard for the quantification of the analyte in biological samples and aqueous samples using enzyme-linked immunosorbent assay (ELISA) and spectrofluorimetic technique.Packaging10, 50, 100 g in glass bottleПараметрыQuality Level 200 grade analytical standard assay 98.0-101.5% form powder application(s) HPLC: suitable, gas chromatography (GC): suitable mp 260-265 °C (dec.) (lit.) Featured Industry Forensics and Toxicology
Pharmaceutical (small molecule)Mode of action DNA synthesis | interferes, enzyme | inhibits format neat SMILES string OC(=O)c1cc(ccc1O)\N=N\c2ccc(cc2)S(=O)(=O)Nc3ccccn3 InChI 1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+ InChI key NCEXYHBECQHGNR-QZQOTICOSA-N Gene Information human ... ALOX5(240), PTGS1(5742), PTGS2(5743)
Safety InformationPictograms GHS08 Signal Word Danger Hazard Statements H317 - H334 Precautionary Statements P261 - P280 - P284 - P304 + P340 - P333 + P313 - P342 + P311 Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves RIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point(F) Not applicable Flash Point(C) Not applicable Узнать цену
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