Sucralose powder

Empirical Formula (Hill Notation):	C12H19Cl3O8
CAS Number:	56038-13-2
Molecular Weight:	397.63
Beilstein/REAXYS Number:	3654410
MDL number:	MFCD03648615
EC Index Number:	259-952-2

Кат. номер
1008940000
1008940010
1008941000
1008949011
1008940011
1008941001
1008949010

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Sucralose is a high-intensity sweetener which is non-cariogenic and suitable for diabetics and patients with an impaired glucose tolerance. In addition, it is readily soluble and masks both bitterness and medicinal off-notes with equal ease – making it exceptionally well-suited for pharmaceutical applications.
Our Sucralose is available in micronized or granular form, both pharmaceutical grade, allowing you to choose depending on your individual needs. Due to its optimal dispersion behavior, sucralose powder is typically recommended for solid dose formulations, while the fast dissolution behavior of sucralose granular makes it very well-suited for liquid formulations.
A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
The substance 1.00894 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

storage conditions	Store at +15°C to +25°C.
Quality Level	500
Agency/Method	ChP, JPE, NF, Ph. Eur.
description	EMPROVE® ESSENTIAL Ph Eur,NF,JPE
product line	EMPROVE® ESSENTIAL
form	powder, crystals or beads
potency	>10000 mg/kg LD50, oral (Rat)
pH	6-8 (20 °C, 100 g/L in H2O)
mp	130 °C (decomposition)
density	1.62 g/cm3 at 20 °C
storage temp.	15-25°C
SMILES string	OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl
InChI	1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
InChI key	BAQAVOSOZGMPRM-QBMZZYIRSA-N