NAD

Empirical Formula (Hill Notation):	C21H27N7O14P2 · xH2O
CAS Number:	53-84-9
Molecular Weight:	663.43 (anhydrous basis)
MDL number:	MFCD00036253
PubChem Substance ID:	329818699

Кат. номер

10127973001

10127965001

Nicotinamide adenine dinucleotide (NAD) is a ubiquitously found electron carrier and a cofactor. NAD+ contains an adenylic acid and a nicotinamide-5-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.
NAD has been used in in vitro glycogen synthase kinase 3 (GSK3) deacetylation assay. It has also been used as a component in assay mix for the determination of kinetic characteristics using an enzyme-linked kinetic assay.
NAD (nicotinamide adenine dinucleotide), Grade I has been used in the kinetic studies of human class IV alcohol dehydrogenase.
Biochem/physiol Actions
NAD is also involved in microbial catabolism. β-NAD acts as a substrate for various enzymes in several cellular processes.
The NAD (nicotinamide adenine dinucleotide)/NADH ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. It works as an electron acceptor.
Electron acceptor
Packaging
Packaged by solid weight.
Quality
Purity: 100% -NAD based on dry weight (enzymatically, CN-complex and absorbance); A250nm - A260nm : 0.83 ± 0.02, A280nm - A260nm : 0.22 ± 0.02
Absence of contaminants: LDH inhibitors are not detectable
Organic solvents: =0.05% (GC)
Specifications
Absorbance coefficients: 17.6 x 103l x mol-1 x cm-1 at 260nm, 5.9 x 103l x mol-1 x cm-1 at 333nm (CN complex)
Preparation Note
Storage conditions (working solution): 10 mg/ml in aqueous solution, contains at least 99% NAD after 4 weeks at 2 to 8 °C
This is the common form of NAD.
For life science research only. Not for use in diagnostic procedures.

assay	100% (dry weight)
form	lyophilized
mol wt	Mr 663.4
packaging	pkg of 1 g (10127965001), pkg of 5 g (10127973001)
Торговая марка	Roche
color	off-white
pH	~3.0 (50 mg/mL in water)
max	260 nm
shipped in	wet ice
storage temp.	2-8°C
SMILES string	NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
InChI	1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI key	BAWFJGJZGIEFAR-NNYOXOHSSA-N

RIDADR

NONH for all modes of transport