Huzzah® S1P 360492P-1EA

NACRES:

NA.25

Avantis new HSA lipid delivery system, Huzzah® improves the cellular delivery of S1P through its conjugation with human serum albumin (HSA), a physiologically relevant carrier protein. This conjugate system eliminates the need for organic solvents, which are well-known to adversely affect viability and the phenotypic characteristics of cells. The Huzzah® lipid delivery system is supplied as a lyophilized conjugate which can be directly and easily reconstituted in water or a buffer of choice and is ideal for studying the effects of poorly soluble bioactive molecules. Solubility: Reconstitute lyophilized conjugate in 5 mL of water or other aqueous buffer. This produces a stock solution of 120 - 200 µM sphingosine-1-phosphate*. A short sonication may be necessary to ensure complete dissolution. If necessary, filter sterilize the reconstituted conjugate prior to use in cell culture applications. *Exact concentration will vary from batch to batch. Refer to label for exact product concentration upon reconstitution as determined by mass spectrometric analysis.Molar Ratio: S1P:albumin (2:1) Albumin Biological Characterization: microbial free; endotoxin < 1 IU/mL Albumin Lipid Characterization: ~0.07g/L phospholipids; ~0.02 g/L sphingolipids; ~0.1 g/L fatty acids; and triglycerides and cholesterols below the limit of quantitation of 0.1 g/L and 0.05 g/L.
Huzzah® S1P has been used:

• to study its role in ovarian cancer (OvCa) tumor progression
• for the differentiation of mouse embryonic stem (ES) cells toward neuronal and glial lineage
• to deliver aqueous soluble lipid species to cells

10 mL Clear Glass Vial with Stopper and Crimp Cap (360492P-1EA)
Huzzah is a registered trademark of Avanti Polar Lipids, Inc.

assay	>99% (MS)
form	powder
Торговая марка	Avanti Polar Lipids
packaging	1 ea of 1 x (with stopper and crimp cap)
shipped in	dry ice
storage temp.	20°C

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable