O-Acetyl-L-carnitine hydrochloride

Empirical Formula (Hill Notation):	C9H17NO4 · HCl
CAS Number:	5080-50-2
Molecular Weight:	239.70
Beilstein/REAXYS Number:	4340103
MDL number:	MFCD00082230
PubChem Substance ID:	24891132
NACRES:	NA.83

Кат. номер

A6706-1G

A6706-5G

A6706-10MG

Acetyl-L-carnitine (ALC/ALCAR), a quasi-vitamin is a metabolite of carnitine, present in mammalian plasma and tissues. It is the acetylated form of L-carnitine (LC). ALCAR is used as a dietary supplement. It is present at high level in the hypothalamus.
O-Acetyl-L-carnitine hydrochloride has been used:

• as a bioactive compound to study its effect on the proliferation of B-lymphoblastoid cell lines (BLCL) and its immune modulating properties on influenza virus specific human B and T cell responses in vitro
• as in vitro maturation (IVM) media component to study its effects on lamb oocyte blastocyst rate, ultrastructure and mitochondrial DNA copy number
• as a metabolite/chemical standard to quantify the metabolite levels in murine tumor interstitial fluid

1, 5 g in poly bottle
Acetyl L-carnitine (ALC) plays a vital role in intermediary metabolism and in improving female fertility. The oxidative and metabolic status of the female reproductive system is controlled by ALC. ALC possesses cholinomimetic and anti-inflammatory effects. It controls -amino butyric acid (GABA) system. ALC is capable of modifying the rate of glucose usage in the brain. It also possesses a neuroprotective role in the developing brain.
Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

biological source	synthetic
Quality Level	300,
assay	99% (titration)
form	powder
optical activity	[]25/D 28°, c = 2 in H2O(lit.)
application(s)	cell analysis: suitable
color	white to off-white
mp	194 °C
solubility	H2O: 100 mg/mL
storage temp.	2-8°C
SMILES string	[Cl-].CC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
InChI	1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
InChI key	JATPLOXBFFRHDN-DDWIOCJRSA-N

pictograms	GHS07
signalword	Warning
hcodes	H315 - H319 - H335
pcodes	P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
Personal Protective Equipment	dust mask type N95 (US),, Eyeshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable