Biotin, immobilized on Dextran

NACRES:

NA.25

Кат. номер

14402-VAR

14402-25MG

14402-10MG

Biotin/vitamin B7/vitamin H is a water-soluble B complex vitamin. It consists of an uredo ring fused by a tetrahydrothiophene ring. Biotin is readily available in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.
Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components. Biotinylated dextran may be used to capture or detect avidin/strepavidin conjugated molecules.
Biotin, immobilized on dextran has been used in in vivo labeling of the lectin structures of vascular endothelium to demonstrate the functionality of CD31+ vessels.
Biotin acts as an important cofactor for carboxylase enzymes in various metabolic pathways. It is implicated in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin functions as a coenzyme in the metabolism of fats, fatty acids and amino acids such as isoleucine and valine. It is involved in gluconeogenesis and citric acid cycle. Biotin is essential for cell growth.It assists the transfer of carbon dioxide and also maintains a steady blood sugar level.

Quality Level	100,
biological source	synthetic
assay	99.0% (TLC)
form	powder
mol wt	Mr ~70000
extent of labeling	5-25 mol/mol substitution (biotin)
application(s)	detection: suitable
color	colorless to white
solubility	H2O: 50 mg/mL, slightly hazy, faintly yellow
storage temp.	2-8°C

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable