Propyl gallate 1576800-200MG
Empirical Formula (Hill Notation): | C10H12O5 |
Linear Formula: | 3,4,5-(HO)3C6H2CO2CH2CH2CH3 |
CAS Number: | 121-79-9 |
Molecular Weight: | 212.20 |
Beilstein/REAXYS Number: | 1877976 |
MDL number: | MFCD00002196 |
PubChem Substance ID: | 329750994 |
NACRES: | NA.24 |
This product is provided as delivered and specified by the issuing Pharmacopoeia. Used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both
in vitro and
in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both
in vitro and
in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 µM when it was combined with copper concentrations at 5 µM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Prepare a 0.1M solution in glycerol:PBS (9:1)
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
USP issued SDS can be found here.
Sales restrictions may apply.
grade | pharmaceutical primary standard |
form | neat |
Торговая марка | USP |
mp | 146-149 °C (lit.) |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
SMILES string | CCCOC(=O)c1cc(O)c(O)c(O)c1 |
InChI | 1S/C10H12O5/c1-2-3-15-10(14)6-4-7(11)9(13)8(12)5-6/h4-5,11-13H,2-3H2,1H3 |
InChI key | ZTHYODDOHIVTJV-UHFFFAOYSA-N |
pictograms | GHS05,GHS07,GHS09 |
signalword | Danger |
hcodes | H302 - H317 - H318 - H410 |
pcodes | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point F | 368.6 °F - closed cup |
Flash Point C | 187 °C - closed cup |