MCAT-53™
Empirical Formula (Hill Notation): | C13H17Cl2NaO6Ru2 |
Molecular Weight: | 565.31 |
PubChem Substance ID: | 329769798 |
NACRES: | NA.22 |
Кат. номер |
900285-1G |
900285-250MG |
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here, for more information.
MCAT-53 is a recyclable ruthenium-containing catalyst for C–C coupling reactions in aqueous conditions. In contrast to Pd-catalyzed reactions, MCAT-53 achieves C–H-activated C–C coupling in water under ligand-free conditions, requiring no co-solvent, surfactant, or additional steps for activation. Bench- and air-stable, MCAT-53 will find wide utility in cost-effective and greener alternatives in pharmaceutical and manufacturing processes. This water-friendly catalyst is offered in collaboration with Chicago Discovery Solutions.
The catalyst has been successfully employed to synthesize a key intermediate of anacetrapib as a single regioisomer.
1 g in glass bottle
250 mg in glass bottle
Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond Activation,
MCAT-53™: A Green Ruthenium Catalyst for Cross-Coupling & C–H Activation,
MCAT-53 is a trademark of Chicago Discovery Solutions LLC
form | powder |
Quality Level | 100, |
reaction suitability | core: ruthenium, reagent type: catalyst reaction type: C-H Activation |
greener alternative product characteristics | Less Hazardous Chemical Syntheses Designing Safer Chemicals Catalysis Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry,. |
mp | 247.8 °C |
greener alternative category | Aligned, |
storage temp. | 2-8°C |
SMILES string | C[Ru]OC([H])=O.[Ru]OC([H])=O.ClC.CC.CC1=CC=C(C(C)C)C=C1.COC([H])=O.Cl.[Na] |
InChI | 1S/C10H14.3CH2O2.2ClH.Na.2Ru.H/c1-8(2)10-6-4-9(3)5-7-10;3*2-1-3;;;;;;/h4-8H,1-3H3;3*1H,(H,2,3);2*1H;;;;/q;;;;;;;+2;+3;/p-5 |
InChI key | QVXXTDGUSONXKR-UHFFFAOYSA-I |
RIDADR | NONH for all modes of transport |
Flash Point F | Not applicable |
Flash Point C | Not applicable |