Sigma-Aldrich
- Сортировать:
- Вид таблицей
-
SILu™Carb Glycan Standard 13C Biantennary bG0
Empirical Formula (Hill Notation): C4813C10H97N5O41 Molecular Weight: 1530.33
Кат. номер ILGBG0-600PMO ILGBG0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G0
Empirical Formula (Hill Notation): C4213C8H84N4O36 Molecular Weight: 1325.15
Кат. номер ILGG0-600PMO ILGG0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G0F
Empirical Formula (Hill Notation): C8213C8H148N6O66 Molecular Weight: 2378.08
Кат. номер ILGG0F-600PMO ILGG0F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(3)
Empirical Formula (Hill Notation): C4813C8H94N4O41 Molecular Weight: 1487.29
Кат. номер ILGG13-600PMO ILGG13-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(6)
Empirical Formula (Hill Notation): C4813C8H94N4O41 Molecular Weight: 1487.29
Кат. номер ILGG16-2000PMO ILGG16-600PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(6)F
Empirical Formula (Hill Notation): C5413C8H104N4O45 Molecular Weight: 1633.43
Кат. номер ILGG16F-600PMO ILGG16F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2
Empirical Formula (Hill Notation): C5413C8H104N4O46 Molecular Weight: 1649.43
Кат. номер ILGG2-600PMO ILGG2-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(3) Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A13S23-600PMO ILG2A13S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(3) Sial(Alpha-2,6)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A13S26-600PMO ILG2A13S26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6) Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A16S23-600PMO ILG2A16S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6)F Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C7113C8H131N5O58 Molecular Weight: 2086.83
Кат. номер IL2A16FS23-600PMO IL2A16FS23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6)F Sial(Alpha-2,6)
Empirical Formula (Hill Notation): C7113C8H131N5O58 Molecular Weight: 2086.83
Кат. номер IL2A16FS26-600PMO IL2A16FS26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2F
Empirical Formula (Hill Notation): C6013C8H114N4O50 Molecular Weight: 1795.57
Кат. номер ILGG2F-600PMO ILGG2F-2000PMO Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Paucimannose Man3
Empirical Formula (Hill Notation): C3013C4H58N2O26 Molecular Weight: 914.79
Кат. номер ILGM3-600PMO ILGM3-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Paucimannose Man5
Empirical Formula (Hill Notation): C4213C4H78N2O36 Molecular Weight: 1239.07
Кат. номер ILGM5-600PMO ILGM5-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G0
Empirical Formula (Hill Notation): C6013C6H110N6O46 Molecular Weight: 1729.55
Кат. номер ILGA4G0-600PMO ILGA4G0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1a
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1A-600PMO ILGA4G1A-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1c
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1C-600PMO ILGA4G1C-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1d
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1D-600PMO ILGA4G1D-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G3abd
Empirical Formula (Hill Notation): C7813C6H140N6O61 Molecular Weight: 2215.97
Кат. номер ILGA4G3ABD-600PMO ILGA4G3ABD-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G3bcd
Empirical Formula (Hill Notation): C7813C6H140N6O61 Molecular Weight: 2215.97
Кат. номер ILGA4G3BCD-600PMO ILGA4G3BCD-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4
Empirical Formula (Hill Notation): C8413C6H150N6O66 Molecular Weight: 2378.11
Кат. номер ILGA4G4-600PMO ILGA4G4-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4-LacNAc
Empirical Formula (Hill Notation): C9813C6H173N7O76 Molecular Weight: 2743.44
Кат. номер ILGA4NALG4-600PMO ILGA4NALG4-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4F-LacNAc
Empirical Formula (Hill Notation): C10413C6H183N7O80 Molecular Weight: 2889.58
Кат. номер ILA4NALG4F-600PMO ILA4NALG4F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G0
Empirical Formula (Hill Notation): C4813C10H97N5O41 Molecular Weight: 1530.33
Кат. номер ILGA3G0-600PMO ILGA3G0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G0F
Empirical Formula (Hill Notation): C5413C10H107N5O45 Molecular Weight: 1676.47
Кат. номер ILGA3G0F-600PMO ILGA3G0F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G3F
Empirical Formula (Hill Notation): C7213C10H137N5O60 Molecular Weight: 2162.89
Кат. номер ILGA3G3F-600PMO ILGA3G3F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C truncated MGn(3)F
Empirical Formula (Hill Notation): C4213C6H81N3O35 Molecular Weight: 1266.11
Кат. номер ILGMGN3F-600PMO ILGMGN3F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C truncated MGn(6)
Empirical Formula (Hill Notation): C3613C6H71N3O31 Molecular Weight: 1119.97
Кат. номер ILGMGN6-600PMO ILGMGN6-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™CHOP Stable-Isotope Labeled CHO Proteins
Кат. номер MSQC12-PH MSQC12-100UG General descriptionContamination of final product with Host Cell Proteins (HCPs) is a major concern for the development and production of Biotherapeutics in CHO cell lines. SILuCHOP is a representative heavy-isotope labeled standard of secreted host cell proteins, thus facilitating identification of biotherapeutics with contaminant host cell proteins by mass spectrometry.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200, packaging vial of 100 µg suitability suitable for , suitable for mass spectrometry shipped in wet ice storage temp. 20°C
Safety Informationpictograms GHS05 signalword Danger hcodes H290 - H314 pcodes P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 RIDADR UN 1824 8 / PGII WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT1, RAC-alpha serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0050-50UG MSST0050-50UG-PW General descriptionSILu™Lite AKT1 is a recombinant human protein expressed in human 293 cells. It consists of 501 amino acids, with a calculated molecular mass of 58.2 kDa (including N-terminal polyhistidine and flag tags). SILu™Lite AKT1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P31749, shipped in dry ice storage temp. 20°C Gene Information human ... AKT1(207)
Safety InformationRIDADR NONH for all modes of transport Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT2, RAC-beta serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0052-50UG MSST0052-50UG-PW General descriptionSILu™Lite AKT2 is a recombinant human protein expressed in human 293 cells. It consists of 502 amino acids, with a calculated molecular mass of 58.2 kDa (including N-terminal polyhistidine and flag tags). SILu™ AKT2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P31751, shipped in dry ice storage temp. 20°C Gene Information human ... AKT2(208)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT3, RAC-gamma serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0054-50UG MSST0054-50UG-PW General descriptionSILu™Lite AKT3 is a recombinant human protein expressed in human 293 cells. It consists of 500 amino acids (including N-terminal polyhistidine and flag tags), with a calculated molecular mass of 58.2 kDa. SILu™Lite AKT3 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid conjugate His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. Q9Y243, shipped in dry ice storage temp. 20°C Gene Information human ... AKT3(10000)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite ALB Albumin human
NACRES: NA.12
Кат. номер MSST0012-50UG MSST0012-50UG-PW General descriptionSILu™Lite ALB is a recombinant human protein expressed in human 293 cells. It is a monomer of 607 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~69 kDa. SILu™Lite ALB is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
Albumin is synthesized exclusively by the liver parenchymal cells at a rate of 14 g/day. While it is the most abundant plasma protein (>50%), increased urine albumin concentrations indicate bleedings in the lower urinary tract (ureter, bladder) or infections of the renal pelvis. A small abnormal albumin excretion is known as Microalbuminuria and serves as an indicator for temporary overload of the glomerular filtration (fever, excessive sports) or chronic injury of the glomeruli (diabetes).
Sequence
RRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02768, shipped in ambient storage temp. 20°C Gene Information human ... ALB(213)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AMBP Alpha-1 Microglycoprotein human
NACRES: NA.12
Кат. номер MSST0014-50UG MSST0014-50UG-PW General descriptionSILu™ Lite AMBP is a recombinant human protein expressed in human 293 cells. It is a monomer of 204 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~23 kDa. SILu™ Lite AMBP is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
AMBP is synthesized by the liver. Approximately half of the circulating protein is complexed to IgA. The free form of AMBP is filtered by the glomerulus and reabsorbed by proximal tubule cells. AMBP has been found to be a sensitive biomarker for proximal tubular dysfunction even in the early phase of injury when no histologic damage is observable. In addition, urinary AMBP has been proposed to be a useful marker of tubular dysfunction even in low-gestational-age preterm infants, a population at high risk for AKI (Acute Kidney Injury). Urinary AMBP is also a marker of kidney damage in type 2 diabetes.
Sequence
GPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIMDRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEPEPILIPRVDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable conjugate His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02760, storage temp. 20°C Gene Information human ... AMBP(259)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOA1 Apolipoprotein A-1 human
Кат. номер MSST0002-50UG MSST0002-50UG-PW
Biochem/physiol Actions
Apolipoprotein A-1(Apo-A1), is a major protein component of high density lipoprotein (HDL)in plasma1. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters2. Apo-A1 was shown to assist in the improvement of predicting cardiovascular events3. The gene that encodes to Apolipoprotein A-1 is APOA1. This gene is closely linked with two other apolipoprotein genes on chromosome 114. Defects in this gene are associated with HDL deficiencies, including Tangier disease5, and with systemic non-neuropathic amyloidosis6. The protein is made up of one major isoform (pI 5.6) and two minor isoforms (pI 5.53 and 5.46). Apo-A1 shows a high content of a-helix structure6. The amphipathic regions in the -helix structure seem to be responsible for lipid binding capacity. In aqueous solution, Apo-A1 shows self-association with minor conformational change7. In addition, it has been shown that Apo-A1 is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin8.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.
Analysis Note
General Description
SILuLite APOA1 is a recombinant human protein expressed in human 293 cells. It is a monomer of 286 amino acids (including N-terminal signal sequence and C-terminal polyhistidine and V5 tags), with a molecular weight of 32.1 kDa. SILuLite APOA1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
RHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQSDPSRGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
The N-terminal signal peptide and C-terminal linker peptide, V5 and polyhistidine tags are italicized.
Other Characterization- Sequence confirmed by intact mass analysis
- Identity verified by peptide mapping
- purity >98% (SDS-PAGE)
- Vial content was determined by the Bradford method using BSA as a calibrator. The correction factor of Bradford-to-AAA is 88.33%
Suggested Quantitative Analysis Parameters
(MRM settings provided for three suggested peptides,)Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder packaging vial of 50-65 µg (Lot-specific vial content given on certificate of analysis) application(s) mass spectrometry (MS): suitable conjugate His tagged","V5 tagged UniProt accession no. P02647, storage temp. 20°C Gene Information human ... APOA1(335)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOA2 Apolipoprotein A-II human
NACRES: NA.12
Кат. номер MSST0030-50UG MSST0030-50UG-PW General descriptionApolipoprotein A-II (ApoA-II) occurs in plasma as a dimer of two 77-amino acid chains linked by a disulfide bridge. After apoA-I, it is the second major protein component of HDL, accounting for approximately 20% of HDL total protein. ApoA-II is thought to play an important role in triglyceride metabolism both from animal and human studies. 3 Recent findings attribute apoA-II to inhibitory effects on lipoprotein lipase-mediated hydrolysis of triglyceride-rich particles. Additional associations of apoA-II have been reported for a variety of protein factors including hepatic lipase (HL), lipoprotein lipase (LPL), endothelial lipase, CETP, PLTP, and LCAT.ImmunogenMAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGLDRIRGRKLGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite APOA2 is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 97 amino acids (including C-terminal polyhistidine and flag tags), with a calculated molecular mass of 11 kDa. SILu Lite APOA2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98 Heavy amino acids incorporation efficiency by MS application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02652, storage temp. 20°C Gene Information human ... APOA2(336)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOB48, Apolipoprotein B-48 human
NACRES: NA.32
Кат. номер MSST0056-50UG MSST0056-50UG-PW General descriptionSILu™Lite APOB48 is a recombinant human protein expressed in human 293 cells. It consists of 2172 amino acids, with a calculated molecular mass of 243.2 kDa (including C-terminal polyhistidine and flag tags). SILu™Lite APOB48 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Apolipoprotein B 48 (APOB48) is a key subunit of APOB. APOB is encoded by the gene mapped to human chromosome 2p24.1.
Biochem/physiol Actions
Apolipoprotein B-48 (Apo B-48) is known to be the only specific marker of intestinal chylomicron (CM) particles. The amino acid sequence of apoB-48 represents 48% of the initial sequence of apolipoprotein B-100 (Apo B-100). Apo B-48 is synthesized only by the intestine in humans, while Apo B-100 is synthesized primarily by the liver. Therefore, Apo B-48 is a most appropriate biomarker for cardiovascular and nutritional investigation of postprandial CM metabolism.In a recent study, Apo B-48 was discovered as a novel biomarker in amyotrophic lateral sclerosis patient fibroblasts.
Apolipoprotein B 48 acts as a ligand for low-density lipoprotein (LDL)-receptor. Elevated levels of APOB is associated with the development of elevated LDL levels and other lipid metabolic disorders. In addition, overexpression of the gene increases the risk of susceptibility to coronary heart disease.
Sequence
EEEMLENVSLVCPKDATRFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPEPSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRILGEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPTGAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATYELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDYPKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKEFNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPALHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTSTDHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSYDGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLKHINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid conjugate FLAG® tagged","His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P04114, shipped in dry ice storage temp. 20°C Gene Information human ... APOB48(338)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOD, Apolipoprotein D human
Кат. номер MSST0062-50UG MSST0062-50UG-PW General descriptionSILu™Lite APOD is a recombinant human protein expressed in human 293 cells. It consists of 189 amino acids (including a C-terminal polyhistidine tag), with a calculated molecular mass of 21.69 kDa. SILu™Lite APOD is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
Apolipoprotein D is a member of the Apolipoprotein family. Unlike other lipoproteins, which are mainly produced in the liver, apolipoprotein D is mainly produced in the brain and testes. It was found to be a putative biomarker of androgen receptor function in androgen insensitivity syndrome, the most common cause of disorders of sex development. Apolipoprotein D is associated with neurological disorders and nerve injury, especially related to myelin sheath. It was shown to be elevated in a rat model of stroke, and is elevated in patients with schizophrenia, bipolar disorder, and Alzheimer′s disease.
Sequence
QAFHLGKCPNPPVQENFDVNKYLGRWYEIEKIPTTFENGRCIQANYSLMENGKIKVLNQELRADGTVNQIEGEATPVNLTEPAKLEVKFSWFMPSAPYWILATDYENYALVYSCTCIIQLFHVDFAWILARNPNLPPETVDSLKNILTSNNIDVKKMTVTDQVNCPKLSDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form lyophilized powder UniProt accession no. P05090, shipped in ambient storage temp. 20°C Gene Information human ... APOD(347)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite B2M beta-2-microglobulin human
NACRES: NA.12
Кат. номер MSST0016-50UG MSST0016-50UG-PW General descriptionSILu™ Lite B2M is a recombinant human protein expressed in human 293 cells. It is a monomer of 119 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~14 kDa. SILu™ Lite B2M is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Suggested Quantitative Analysis Parameters
(MRM settings provided for three suggested peptides,)
Biochem/physiol Actions
B2M is the light chain of the major histocompatibility class (MHC) I molecule expressed on the cell surface of all nucleated cells. Increased urinary B2M excretion has been observed to be an early marker of tubular injury in a number of settings, including nephrotoxicant exposure, cardiac surgery, and renal transplantation, preceding rises in serum creatinine by as many as 4−5 days. B2M may also serve as an early biomarker for AKI (Acute Kidney Injury).
Sequence
IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDMDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P61769, storage temp. 20°C Gene Information human ... B2M(567)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite CCL2 C-C motif chemokine 2 human
NACRES: NA.12
Кат. номер MSST0036-50UG MSST0036-50UG-PW General descriptionCCL2, the most thoroughly characterized CC chemokine, is a monocyte-specific chemoattractant that was demonstrated to attract T lymphocytes and NK cells, but not neutrophils. Enhanced expression of CCL2 was demonstrated in a variety of pathologic conditions, associated with inflammation and mononuclear cell infiltration. Extensive experimental evidence suggests that CCL2 is highly expressed in atherosclerotic plaques. In a recent study, CCL2 was shown to have value as a biomarker for risk stratification in both the initial and the chronic phases after an acute coronary syndromes (ACS). In contrast to CRP, CCL2 levels may be an indicator of long-term cardiovascular risk rather than a marker of acute prognosis. In urine, CCL2 levels were directly associated to Systemic Lupus Erythematosus disease activity, making it a non-invasive biomarker (avoiding blood sampling or tissue biopsies).ImmunogenQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKTDYKDDDDKGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite CCL2 is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 96 amino acids (including C-terminal polyhistidine and FLAG® tags), with a calculated molecular mass of 11 kDa. SILu Lite CCL2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Lyophilized from a solution of phosphate buffered saline.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98% Heavy amino acids incorporation efficiency by MS application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P13500, storage temp. 20°C Gene Information human ... CCL2(6347)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite CLU Clusterin human
Кат. номер MSST0008-50UG MSST0008-50UG-PW General descriptionSILu™Lite Clusterin is a recombinant human protein expressed in human 293 cells. It is a heterodimer of 2 subunits (alpha and beta) consisting of 427 amino acids (including N-terminal polyhistidine and V5 tags), with a calculated molecular weight of 50 kDa. SILu™Lite Clusterin is designed to be used as an internal standard for bioanalysis of Clusterin in mass-spectrometry.
Biochem/physiol Actions
Clusterin is a secreted glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including anti-apoptotic cell survival, cell cycle regulation, cell adhesion, tissue remodeling and lipid transportation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
Sequence
DQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREESDPSRGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P10909, storage temp. 20°C Gene Information human ... CLU(1191)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite COL1A1 N-terminal propeptide human
Кат. номер MSST0034-50UG MSST0034-50UG-PW General descriptionCollagen type I is present in soft connective tissues and bone, where it constitutes more than 90% of the organic matrix.1 During bone formation collagen type I is synthesized from pro-collagen type I, which is secreted from fibroblasts and osteoblasts.2 Pro-collagen type I contains N-and C-terminal extensions, which are removed by specific proteases during the conversion of procollagen to collagen.3 Measurements of N- terminal propeptides of procollagen type I (PINP) can be of value in assessing bone formation. Recent evidence indicates that PINP can serve as a serum biomarker of bone formation, as it accurately identifies those patients who are responding to anabolic or antiresorptive therapy within 3 months of the start of treatment.4 The use of this biomarker in patients being treated for osteoporosis may significantly improve therapy adherence and clinical outcomes.4ImmunogenQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPDYKDDDDKGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite COL1A1 recombinant human protein expressed in human 293 cells. It is a protein of 159 amino acids (Q23-P161 and including C-terminal polyhistidine and FLAG® tags) with a calculated molecular mass of 16 kDa. SILu Lite COL1A1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Lyophilized from a solution of phosphate buffered saline.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98% Heavy amino acids incorporation efficiency by MS application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02452, storage temp. 20°C Gene Information human ... COL1A1(1277)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite CRP C-reactive Protein human
NACRES: NA.12
Кат. номер MSST0022-50UG MSST0022-50UG-PW General descriptionSILu™Lite CRP is a recombinant human protein expressed in human 293 cells. It is a protein consisting of 226 amino acids (including a C-terminal polyhistidine and FLAG® tags), with a calculated molecular weight of ~25 kDa. SILu™Lite CRP is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Suggested Quantitative Analysis Parameters
(MRM settings provided for three suggested peptides,)
Biochem/physiol Actions
CRP is a hepatically derived pentraxin. It exists mainly as a pentamer in a cyclic structure with 5 identical 23-kD subunits in the blood. In addition to its role as an "acute phase" protein or first-line defense molecule against pathogenic organisms, baseline levels of CRP correlate positively to adverse cardiovascular events. CRP is therefore being considered a “risk factor” for cardiovascular disease. In humans, treatment with statin therapy reduces levels of both LDL-C and CRP, and concurrently there is a reduction in the number of cardiovascular events. A recent study suggests that patients with elevated basal levels of CRP are at an increased risk of diabetes, in addition to cardiovascular disease. A study of over 700 nurses showed that those in the highest quartile of trans fat consumption had blood levels of CRP that were 73% higher than those in the lowest quartile.
Sequence
QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWPDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a solution of phosphate buffered saline with 25% glycerol.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form liquid application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02741, storage temp. 20°C Gene Information human ... PTX3(5806)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite CST3, Cystatin C human
NACRES: NA.32
Кат. номер MSST0060-50UG MSST0060-50UG-PW General descriptionSILu™Lite CST3 is a recombinant human protein expressed in E. coli. It consists of 120 amino acids, with a calculated molecular mass of 13.5 kDa. SILu™Lite CST3 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
Cystatin C is an inhibitor of cysteine proteases including cathepsin B (which has been identified as the most important ?-amyloid-degrading enzyme. Measurement of cystatin C in serum is replacing creatinine as an indicator of kidney function (glomerular filtration rate, GFR).
Sequence
SSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA
Physical form
Supplied as a lyophilized powder containing tris buffered saline and methionine.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 recombinant expressed in E. coli assay 95% (SDS-PAGE) form lyophilized powder suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P01034 (aa 27-146), shipped in ambient storage temp. 20°C Gene Information human ... CST3(1471)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite HAVCR1 Hepatitis A virus cellular receptor 1 human
NACRES: NA.12
Кат. номер MSST0042-50UG MSST0042-50UG-PW General descriptionHAVCR1 is a trans-membrane glycoprotein that is highly expressed in kidney proximal tubular cells with kidney injury. The KIM-1 ectodomain is cleaved, released into urine, and canbe quantied as a sensitive and specic biomarker for Acute Kidney Injury (AKI) in rodents and humans. In a recent study it was demonstrated that HAVCR1 is released into the circulation where it reports kidney injury in mice, rats, and humans with AKI and chronic kidney disease (CKD). Urinary HAVCR1 and MCP-1 levels, either alone or in combination, were significantly higher than those in AKI negative patients. Importantly, the combination of HAVCR1 and MCP-1 outperformed either biomarker alone.ImmunogenSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGDYKDDDDKGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite HAVCR1 is a recombinant human protein expressed in human 293 cells. It is a protein consisting of 290 amino acids acids (the extracellular domain: Ser21-Gly290, and including C-terminal polyhistidine and FLAG® tags), with a calculated molecular mass of 31 kDa. SILu Lite HAVCR1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98% Heavy amino acids incorporation efficiency by MS mol wt calculated mol wt 31 kDa application(s) mass spectrometry (MS): suitable conjugate 8-His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. Q96D42, storage temp. 20°C Gene Information human ... HAVCR1(26762)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite IFNG Interferon Gamma human
NACRES: NA.12
Кат. номер MSST0040-50UG MSST0040-50UG-PW General descriptionInterferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.ImmunogenQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG
Biochem/physiol Actions
SILu™Lite IFNG is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 138 amino acids Expressed in human 293 cells, with a calculated molecular mass of 17 kDa. SILu Lite IFNG is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Lyophilized from a solution of phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98% Heavy amino acids incorporation efficiency by MS mol wt calculated mol wt 17 kDa application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P01579, storage temp. 20°C Gene Information human ... IFNG(3458)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite IGFBP7 Insulin-like growth factor-binding protein 7 human
NACRES: NA.12
Кат. номер MSST0038-50UG MSST0038-50UG-PW General descriptionSILu™ Lite IGFBP7 is a recombinant human protein expressed in human 293 cells. It is a protein consisting of 267 amino acids (including an N-terminal polyhistidine tag), with a calculated molecular mass of 28 kDa. SILu Lite IGFBP7 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
IGFBP7 (insulin-like growth factor-binding protein 7) belongs to the IGFBP superfamily and is widely expressed in tissues. It contains 11 cysteines, a heparin binding site, a kazal-type trypsin inhibitor domain and a carboxyl-terminal immunoglobulin-like type C repeat. IGFBP7 binds weakly to IGFs (insulin like growth factors) and strongly to insulin. It mainly participates in IGF-independent pathways. The IGFBP7 gene is mapped to human chromosome 4q12.ImmunogenHHHHHHHHGGQSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL
Biochem/physiol Actions
SILu™Lite IGFBP7 is a recombinant human protein expressed in human 293 cells. It is a protein consisting of 267 amino acids (including an N-terminal polyhistidine tag), with a calculated molecular mass of 28 kDa. SILu Lite IGFBP7 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
IGFBP7 (insulin-like growth factor-binding protein 7) acts as a tumor suppressor as well as an oncogene by controlling cell proliferation, cell attachment, apoptosis and angiogenesis. It is also involved in TGFβ (transforming growth factor beta) signal pathway. IGFBP7 interferes with the insulin pathway and is associated with the development of diabetes as well as cardiovascular diseases.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98 Heavy amino acids incorporation efficiency by MS application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. Q16270, storage temp. 20°C Gene Information human ... IGFBP7(3490)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену
Получите коммерческое предложение в течение 1 часа
Менеджер подготовит коммерческое предложение и позвонит, если понадобится уточнить детали вашего заказа
Анна Гловацкая
Менеджер по работе с клиентами
С 2010 года мы поставляем оборудование с заводов Европы. Берем на себя все — от подбора оборудования до внедрения на предприятии
Все сотрудники имеют высшее образование, закончили ведущие химические вузы страны, такие как РХТУ им Менделеева.
У большинства компаний срок ожидания составляет 10-12 недель.
Оборудование хранится на сухом отапливаемом складе, где поддерживается ровная температура.
Работаем с PonyExpress и Деловыми линиями. Вы также можете выбрать свою транспортную компанию или забрать товар со склада в Москве.
В случае любых неполадок за свой счет выполним ремонт в сервисном центре или на заводе-изготовителе. Или бесплатно заменим прибор на новый.
Производим пуско-наладку оборудования, валидацию, обучение сотрудников. Если нужно, привлекаем инженеров с заводов- изготовителей.
