Induced pluripotent stem cells (iPSCs) are adult cells that have been reprogrammed to an embryonic stem cell–like state. The cells can replicate indefinitely or, under controlled conditions, can be differentiated into any other cell type such as nerve, heart or liver cells. Medical researchers are able to use iPS cells to test how different patients might respond to new drugs or to analyse how genetic diseases develop.
The EBiSC stem cell bank, is a collection of human iPS cells available to academic and commercial researchers for use in disease modelling and other forms of stem cell research. The initial collection has been generated from a wide range of donors representing specific disease backgrounds and healthy controls. EBiSC has established many routine procedures for collecting, expanding and characterizing human iPS cell lines. The stem cell bank includes iPSC cell lines derived from neurodegenerative diseases (Alzheimers Disease, Parkinsons Disease, Dementia, Motor Neuron Disease (ALS) - and Huntingtons Disease), eye and heart diseases, and lines from healthy control donors for age and sex matching.
DepositorStemBANCC
DerivationPrimary cell type: Erythroblast
Reprogramming method
Vector type: Non-integrating
Vector: Sendai virus
Is the reprogramming vector detectable: Unknown
Xeno free conditions: no
Derived under gmp: no
Available as clinical grade: no
CharacterizationMicrobiology / Virus Screening
HIV 1: Negative
HIV 2: -
Hepatitis B: Negative
Hepatitis C: Negative
Mycoplasma: Negative
GenotypingKaryotyping
Cell line karyotype: No abnormalities detected
Karyotyping method: Molecular karyotyping by SNP array
Additional Cell Line Info,
EBiSC Access Use Agreement (EAUA),Cell Line Information Pack (CLIP),Note: EAUA and CLIP must be completed before order fulfillment
Surface coating: Matrigel®/Geltrex®
Passage method: Enzyme-free cell dissociation / EDTA
O2 concentration: 21%
CO2 concentration: 5%
Culture medium: mTeSR® 1
EBiSC is a trademark of Fraunhofer-Gesellschaft
GELTREX is a registered trademark of Life Technologies Corporation
Matrigel is a registered trademark of Corning, Inc.
mTeSR is a registered trademark of WiCell Research Institute, Inc.
biological source | human erythroblast |
reprogramming method | Sendai virus |
description | age (N/A) |
Торговая марка | EBiSC™ |
gender | female |
growth mode | adherent (pluripotent) |
application(s) | cell culture | stem cell: suitable |
relevant disease(s) | drug-induced liver injury |
shipped in | dry ice |
storage temp. | 196°C |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |