Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody produced in rabbit

MDL number:	MFCD02096426
NACRES:	NA.41

Кат. номер

G0166-25UG-PW

G0166-25UG

synthetic peptide representing the sequence of the C1 splice variant.
Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody is suitable for immunohistochemistry (frozen sections) at a dilution of 1:1000-1:2000 and western blot at 1:1000 dilution using rat and mouse tissue.
Biochem/physiol Actions
NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.
Physical form
Lyophilized powder from 5 mM ammonium bicarbonate, so some residual salt may be present
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source	rabbit
Quality Level	100
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	lyophilized powder
mol wt	antigen 100 kDa
species reactivity	rat, mouse
packaging	antibody small pack of 25 µg
application(s)	immunohistochemistry (frozen sections): 1:1000-1:2000","western blot: 1:1000 using rat and mouse tissue
conjugate	unconjugated
UniProt accession no.	P35439,
storage temp.	2-8°C
Gene Information	mouse ... Grin1(14810) rat ... Grin1(24408)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable