Sigma-Aldrich

100, 250, 500 mg in poly bottle
1 g in poly bottle

L-Glutamic acid -monohydroxamate [L-Glu(gamma)HXM] is used as a vanadium ligand which potentiates vanadiums metabolic activity. L-Glu(gamma)HXM is also used as a substrate for E. coli asparagine synthetase B and as an ATP-dependent irreversible inhibitor of Escherichia coli gamma-glutamylcysteine synthetase.

Quality Level	200,
assay	97% (TLC)
form	powder
application(s)	detection: suitable
color	white to off-white
storage temp.	20°C
SMILES string	NC(CCC(=O)NO)C(O)=O
InChI	1S/C5H10N2O4/c6-3(5(9)10)1-2-4(8)7-11/h3,11H,1-2,6H2,(H,7,8)(H,9,10)
InChI key	YVGZXTQJQNXIAU-UHFFFAOYSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutamic acid di-tert-butyl ester hydrochloride

Empirical Formula (Hill Notation):	C₁₃H₂₅NO₄ · HCl
CAS Number:	32677-01-3
Molecular Weight:	295.80
Beilstein/REAXYS Number:	3573738
MDL number:	MFCD00058003
PubChem Substance ID:	24895307
NACRES:	NA.26

Glutamic acid di-tert butyl ester (GTBE) possesses convulsant properties in mice and rats. It might have unique pharmacological features that set it apart from other convulsant medications.
L-Glutamic acid di-tert-butyl ester is C-terminal and R-chain blocked derivative of L-glutamate that may be useful in the synthesis of substance P antagonistic peptides.

assay	98%
Quality Level	200,
form	powder
color	white
storage temp.	20°C
SMILES string	Cl[H].[H][C@](N)(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C
InChI	1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1
InChI key	LFEYMWCCUAOUKZ-FVGYRXGTSA-N

L-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutamic acid monosodium salt hydrate

Empirical Formula (Hill Notation):	C₅H₈NNaO₄ · xH₂O
CAS Number:	142-47-2
Molecular Weight:	169.11 (anhydrous basis)
EC Number:	205-538-1
MDL number:	MFCD00013074
PubChem Substance ID:	24895237
NACRES:	NA.75

L-Glutamic acid monosodium salt hydrate has been used:

to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
as a component in YNG (yeast nitrogen base glutamate) medium
used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
as a component of fresh media to culture neurons and to assess glutamate uptake

1 kg in poly bottle
100, 500 g in poly bottle

Monosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Quality Level	200,
product line	BioReagent
assay	99%
form	powder
application(s)	cell culture \| insect: suitable, cell culture \| mammalian: suitable
color	white to off-white
mp	163 °C
InChI	1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;
InChI key	JYDGDQPVBSBYRT-UHFFFAOYSA-N

L-Glutamic acid, an amino acid is mainly found in various food products in its free form. It is ubiquitously present in the brain of mammals.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutamic acid potassium salt monohydrate

Empirical Formula (Hill Notation):	C₅H₈KNO₄ · H₂O
CAS Number:	6382-01-0
Molecular Weight:	203.23
Beilstein/REAXYS Number:	3637377
MDL number:	MFCD00150343
PubChem Substance ID:	24895045

L-Glutamic acid potassium salt monohydrate has been used as a component in KG buffer for cardiomyocyte isolation and culture.

100, 500 g in poly bottle

L-Glutamic acid plays a major role in several metabolic pathways. It acts as excitatory neurotransmitter in the cerebral cortex. An plays a key role in learning, memory and brain aging processes. It is involved in neuronal differentiation, migration and survival in the developing brain. High levels of glutamic acid is observed in Alzheimers, Parkinsons diseases and epilepsy.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Quality Level	200,
product line	BioReagent
assay	99% (HPLC)
form	powder
application(s)	cell culture \| insect: suitable
color	white
SMILES string	O.[K+].N[C@@H](CCC([O-])=O)C(O)=O
InChI	1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1
InChI key	XIBUKSQTWSKJMQ-QTNFYWBSSA-M

L-Glutamine has been used as one of the components for the preparation of calcium-free mCZB medium. It has also been used as a supplement in a culture medium for rat hippocampal slices.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutamine

Empirical Formula (Hill Notation):	C₅H₁₀N₂O₃
Linear Formula:	H₂NCOCH₂CH₂CH(NH₂)CO₂H
CAS Number:	56-85-9
Molecular Weight:	146.14
Beilstein/REAXYS Number:	1723797
EC Number:	200-292-1
MDL number:	MFCD00008044
eCl@ss:	32160406
PubChem Substance ID:	24895342
NACRES:	NA.26

10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottle

Glutamine provides the necessary nitrogen, carbon and the reducing equivalents required for cell growth and division during cell culture. L-Glutamic acid aids the incorporation of NH4+ into biomolecules.
L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Quality Level	200
biological source	non-animal source
Agency/Method	meets USP testing specifications
assay	99.0-101.0%
form	powder
application(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested
color	white
mp	185 °C (dec.) (lit.)
solubility	H₂O: 25 mg/mL
Featured Industry	Agriculture
SMILES string	N[C@@H](CCC(N)=O)C(O)=O
InChI	1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI key	ZDXPYRJPNDTMRX-VKHMYHEASA-N
Gene Information	rat ... Ggt1(116568)

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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L-Glutamine solution G2150-20ML

CAS Number:	56-85-9
MDL number:	MFCD00008044
eCl@ss:	32160406
PubChem Substance ID:	24895088
NACRES:	NA.75

L-glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Preparation Note

Prepared in cell culture grade water.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Quality Level	400,
grade	Hybri-Max^™
sterility	sterile-filtered
assay	99% (TLC)
form	solution
application(s)	cell culture \| hybridoma: suitable
impurities	endotoxin, tested
color	clear colorless
shipped in	dry ice
storage temp.	20°C
SMILES string	N[C@@H](CCC(N)=O)C(O)=O
InChI	1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI key	ZDXPYRJPNDTMRX-VKHMYHEASA-N
Gene Information	rat ... Ggt1(116568)

L-glutamine is an essential amino acid that is a crucial component of culture media, which serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

RIDADR	NONH for all modes of transport
WGK Germany	nwg
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutamine solution

CAS Number:	56-85-9
EC Number:	200-292-1
MDL number:	MFCD00008044
PubChem Substance ID:	24895310
NACRES:	NA.75

Prepared in cell culture grade water.

Preparation Note

Quality Level	400
sterility	sterile-filtered
product line	BioXtra
form	solution
concentration	200 mM
application(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested
shipped in	dry ice
storage temp.	20°C
SMILES string	N[C@@H](CCC(N)=O)C(O)=O
InChI	1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI key	ZDXPYRJPNDTMRX-VKHMYHEASA-N
Gene Information	rat ... Ggt1(116568)

L-Glutamine t-butyl ester a C-terminally blocked α amino acid that may be useful in studies of glutamine transport.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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L-Glutamine t-butyl ester hydrochloride

Empirical Formula (Hill Notation):	C₉H₁₈N₂O₃ · HCl
CAS Number:	39741-62-3
Molecular Weight:	238.71
MDL number:	MFCD00039081
PubChem Substance ID:	24895370
NACRES:	NA.26

assay	98%
Quality Level	200,
form	crystalline
application(s)	cell analysis: suitable
color	white
storage temp.	20°C
SMILES string	Cl.CC(C)(C)OC(=O)C(N)CCC(N)=O
InChI	1S/C9H18N2O3.ClH/c1-9(2,3)14-8(13)6(10)4-5-7(11)12;/h6H,4-5,10H2,1-3H3,(H2,11,12);1H
InChI key	ZEPNUNKDKQACNC-UHFFFAOYSA-N

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutathione oxidized

Empirical Formula (Hill Notation):	C₂₀H₃₂N₆O₁₂S₂
CAS Number:	27025-41-8
Molecular Weight:	612.63
Beilstein/REAXYS Number:	1718700
EC Number:	248-170-7
MDL number:	MFCD00063106
PubChem Substance ID:	24895174
NACRES:	NA.26

1, 5 g in poly bottle
100, 250, 500 mg in poly bottle

L-Glutathione, oxidized is frequently measure in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.

Quality Level	200,
assay	98%
form	lyophilized powder
application(s)	detection: suitable
impurities	Ethanol, free
color	white
solubility	H₂O: 50 mg/mL, clear, colorless
storage temp.	2-8°C
SMILES string	N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
InChI	1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1
InChI key	YPZRWBKMTBYPTK-BJDJZHNGSA-N

(-Glu-Cys-Gly) (-Glu-Cys-Gly) [Disulfide bridge: 2a-2b]

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutathione oxidized disodium salt

Empirical Formula (Hill Notation):	C₂₀H₃₀N₆Na₂O₁₂S₂
CAS Number:	103239-24-3
Molecular Weight:	656.59
Beilstein/REAXYS Number:	6265389
MDL number:	MFCD00148894
PubChem Substance ID:	24895179
NACRES:	NA.26

L-Glutathione oxidized disodium salt has been used in 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB)/glutathione reductase enzyme recycling method to determine plasma or tissue glutathione levels. It has also been used in NADPH-dependent glutathione disulfide reduction assay.

1, 5 g in poly bottle
100, 250, 500 mg in poly bottle

Oxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.

Quality Level	200,
assay	98%
form	powder
application(s)	HPLC: suitable
impurities	ethanol, essentially free
color	white to off-white
storage temp.	20°C
SMILES string	[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O
InChI	1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1
InChI key	DRFILBXQKYDTFW-JIWRMXRASA-L

L-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads. It has been used to prepare a standard curve for GSH analyses.
May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Glutathione reduced

Empirical Formula (Hill Notation):	C₁₀H₁₇N₃O₆S
Linear Formula:	H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H
CAS Number:	70-18-8
Molecular Weight:	307.32
Beilstein/REAXYS Number:	1729812
EC Number:	200-725-4
MDL number:	MFCD00065939
PubChem Substance ID:	24895164
NACRES:	NA.26

10 mg in glass bottle
300 mg in poly bottle
1, 5, 10, 25, 50, 100, 250, 500 g in poly bottle

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Reduced L-glutathione (GSH) is a thiol compound and is associated with catabolism and transportation. Plasma GSH levels are associated with Parkinson′s diseases, Alzheimer′s, diabetes, macular degeneration, and HIV (human immunodeficiency virus) disease.

Quality Level	300
assay	98.0%
form	powder
application(s)	detection: suitable
color	white
mp	192-195 °C (dec.) (lit.)
storage temp.	2-8°C
SMILES string	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
InChI	1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChI key	RWSXRVCMGQZWBV-WDSKDSINSA-N

L-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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L-Histidine

Empirical Formula (Hill Notation):	C₆H₉N₃O₂
CAS Number:	71-00-1
Molecular Weight:	155.15
Beilstein/REAXYS Number:	84088
EC Number:	200-745-3
MDL number:	MFCD00064315
eCl@ss:	32160406
PubChem Substance ID:	24895816
NACRES:	NA.26

5, 10, 25, 100, 500 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

L-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Quality Level	200
product line	ReagentPlus^®
assay	99% (TLC)
form	powder
application(s)	cell analysis: suitable
color	white to off-white
mp	282 °C (dec.) (lit.)
solubility	0.5 M HCl: 50 mg/mL
SMILES string	N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI	1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI key	HNDVDQJCIGZPNO-YFKPBYRVSA-N
Gene Information	human ... CA1(759), CA2(760)

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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L-Histidine -naphthylamide

Empirical Formula (Hill Notation):	C₁₆H₁₆N₄O
CAS Number:	7424-15-9
Molecular Weight:	280.32
EC Number:	231-052-4
MDL number:	MFCD00051166
PubChem Substance ID:	24895761
NACRES:	NA.26

250 mg in glass bottle

L-Histidine β-naphthylamide is an analogue of L-histidine used to study structural roles of L-histidine in functions such as the activation of HutP protein transcription. L-Histidine β-naphthylamide may also be used to study the specificity and kinetics of various proteases and peptidases.

assay	98% (TLC)
Quality Level	200,
form	powder
color	white to faint yellow
storage temp.	20°C
SMILES string	N[C@@H](Cc1cnc[nH]1)C(=O)Nc2ccc3ccccc3c2
InChI	1S/C16H16N4O/c17-15(8-14-9-18-10-19-14)16(21)20-13-6-5-11-3-1-2-4-12(11)7-13/h1-7,9-10,15H,8,17H2,(H,18,19)(H,20,21)/t15-/m0/s1
InChI key	DKDILZBBFKZMRO-HNNXBMFYSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type P1 (EN143) respirator filter,, type P3 (EN 143) respirator cartridges,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Histidine dihydrochloride

Empirical Formula (Hill Notation):	C₆H₉N₃O₂ · 2HCl
CAS Number:	6027-02-7
Molecular Weight:	228.08
Beilstein/REAXYS Number:	6119230
EC Number:	227-890-5
MDL number:	MFCD00066569
PubChem Substance ID:	57651406
NACRES:	NA.26

Кат. номер

53340-50G

53340-10G

L-Histidine is a positively charged imidazole-side chain containing amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.
L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.

Quality Level	100,
assay	99.0% (AT)
form	powder or crystals
optical activity	[]20/D +6.5±1°, c = 8% in H₂O
ign. residue	0.1% (as SO₄)
color	white
mp	240-245 °C (dec.)
solubility	H₂O: soluble, saline: soluble
anion traces	sulfate (SO₄^2-): 50 mg/kg
cation traces	As: 0.1 mg/kg, Cd: 5 mg/kg, Co: 5 mg/kg, Cu: 5 mg/kg, Fe: 5 mg/kg, NH₄⁺: 500 mg/kg, Ni: 5 mg/kg, Pb: 5 mg/kg, Zn: 5 mg/kg
SMILES string	Cl.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI	1S/C6H9N3O2.2ClH/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);2*1H/t5-;;/m0../s1
InChI key	XEJCDBUNISUVGZ-XRIGFGBMSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Histidine methyl ester dihydrochloride

Empirical Formula (Hill Notation):	C₇H₁₁N₃O₂ · 2HCl
CAS Number:	7389-87-9
Molecular Weight:	242.10
Beilstein/REAXYS Number:	3572009
EC Number:	230-973-9
MDL number:	MFCD00012701
eCl@ss:	32160406
PubChem Substance ID:	24895465
NACRES:	NA.22

Quality Level	100,
assay	97%
optical activity	[]20/D +9.0°, c = 2 in H₂O
reaction suitability	reaction type: solution phase peptide synthesis
application(s)	peptide synthesis: suitable
color	white
mp	207 °C (dec.) (lit.)
SMILES string	Cl.Cl.COC(=O)[C@@H](N)Cc1c[nH]cn1
InChI	1S/C7H11N3O2.2ClH/c1-12-7(11)6(8)2-5-3-9-4-10-5;;/h3-4,6H,2,8H2,1H3,(H,9,10);2*1H/t6-;;/m0../s1
InChI key	DWAYENIPKPKKMV-ILKKLZGPSA-N

L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.
L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Histidine monohydrochloride monohydrate

Empirical Formula (Hill Notation):	C₆H₉N₃O₂ · HCl · H₂O
CAS Number:	5934-29-2
Molecular Weight:	209.63
Beilstein/REAXYS Number:	4168261
MDL number:	MFCD00151027
eCl@ss:	32160406
PubChem Substance ID:	24895703
NACRES:	NA.26

25, 100 g in poly bottle
1 kg in poly bottle

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

biological source	non-animal source
Quality Level	200,
Agency/Method	meets EP testing specifications
product line	BioXtra
assay	98.5-101.0%
form	crystalline powder
application(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested
color	white
mp	254 °C (dec.) (lit.)
solubility	H₂O: 100 mg/mL
SMILES string	O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI	1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI key	CMXXUDSWGMGYLZ-XRIGFGBMSA-N

L-Histidinol dihydrochloride has been used:

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P264 - P280 - P305 + P351 + P338 - P337 + P313
Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Histidinol dihydrochloride

Empirical Formula (Hill Notation):	C₆H₁₁N₃O · 2HCl
CAS Number:	1596-64-1
Molecular Weight:	214.09
Beilstein/REAXYS Number:	3914853
EC Number:	216-482-2
MDL number:	MFCD00078058
PubChem Substance ID:	24895755
NACRES:	NA.32

as a reagent in urinary metabolite analysis
for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
for inducing amino acid deprivation in HepG2 cells

1, 5 g in poly bottle
10 mg in glass bottle

Precursor of histamine; reversible inhibitor of protein synthesis.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H6647.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,

Quality Level	200,
assay	98 (TLC)
form	powder
application(s)	cell analysis: suitable
color	white to off-white
mp	198-201 °C (dec.) (lit.)
SMILES string	Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1
InChI	1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1
InChI key	FRCAFNBBXRWXQA-XRIGFGBMSA-N
Gene Information	human ... HRH1(3269) mouse ... HRH1(15465) rat ... HRH1(24448)

L-Homoarginine may be used to create non-natural proteins for studies of post-translational protein modifications. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements. L-Homoarginine is used to study the mechanisms of nitric oxide production by cells via nitric oxide synthase(s). L-Homoarginine is used as a selective mammalian alkaline phosphatase isoenzyme inhibitor. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin.
The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

pictograms	GHS07
signalword	Warning
hcodes	H315 - H319 - H335
pcodes	P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
Personal Protective Equipment	dust mask type N95 (US),, Eyeshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homoarginine hydrochloride

Empirical Formula (Hill Notation):	C₇H₁₆N₄O₂ · HCl
Linear Formula:	H₂NC(=NH)NH(CH₂)₄CH(NH₂)CO₂H · HCl
CAS Number:	1483-01-8
Molecular Weight:	224.69
Beilstein/REAXYS Number:	4016621
EC Number:	216-045-6
MDL number:	MFCD00012622
PubChem Substance ID:	24895420
NACRES:	NA.26

5 g in poly bottle

Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.

Quality Level	200,
assay	98% (TLC)
form	powder
application(s)	peptide synthesis: suitable
color	white to off-white
mp	213-215 °C (lit.)
solubility	H₂O: soluble
SMILES string	Cl[H].N[C@@H](CCCCNC(N)=N)C(O)=O
InChI	1S/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/m0./s1
InChI key	YMKBVNVCKUYUDM-JEDNCBNOSA-N

L-Homocysteic acid has been used to study hydrogen peroxide-mediated changes in physiological and pathological conditions in the nervous system.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homocysteic acid

Empirical Formula (Hill Notation):	C₄H₉NO₅S
CAS Number:	14857-77-3
Molecular Weight:	183.18
MDL number:	MFCD00066018
PubChem Substance ID:	24895863
NACRES:	NA.32

1 g in poly bottle
25, 100, 250 mg in poly bottle

L-Homocysteic acid (L-HCA) is an endogenous neurotransmitter ligand of NMDA (N-methyl-D-aspartate) receptors. It is an analog of glutamate and competitively suppresses glutamate-cystine (xc-) antiporter function in neurons, causing decrease in cysteine uptake.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H9633.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,

assay	98% (TLC)
Quality Level	200,
form	powder
application(s)	cell analysis: suitable
color	white to off-white
SMILES string	N[C@@H](CCS(O)(=O)=O)C(O)=O
InChI	1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1
InChI key	VBOQYPQEPHKASR-VKHMYHEASA-N

1, 5 g in glass bottle
100, 250 mg in glass bottle

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homocysteine thiolactone hydrochloride

Empirical Formula (Hill Notation):	C₄H₇NOS · HCl
CAS Number:	31828-68-9
Molecular Weight:	153.63
Beilstein/REAXYS Number:	3911455
EC Number:	250-824-1
MDL number:	MFCD00065494
eCl@ss:	32160406
PubChem Substance ID:	24895745
NACRES:	NA.26

L-Homocysteine thiolactone, an amine reactive agent, is used to study post-translational modification of proteins, especially at lysine residues.

Quality Level	200,
assay	98% (TLC)
form	powder
application(s)	detection: suitable, peptide synthesis: suitable
color	white
mp	185 °C
SMILES string	Cl[H].N[C@H]1CCSC1=O
InChI	1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key	ZSEGSUBKDDEALH-DFWYDOINSA-N

100, 500 mg in poly bottle
1 g in poly bottle

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homocystine

Empirical Formula (Hill Notation):	C₈H₁₆N₂O₄S₂
CAS Number:	626-72-2
Molecular Weight:	268.35
Beilstein/REAXYS Number:	1728583
EC Number:	210-962-5
MDL number:	MFCD00020391
PubChem Substance ID:	24895724
NACRES:	NA.26

L-Homocystine is the oxidized member of the L-homocysteine:L-homocystine pair. Homocysteine/homocystine is derived from methionine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

Quality Level	300,
assay	98% (HPLC)
form	powder
application(s)	cell analysis: suitable, peptide synthesis: suitable
color	white to off-white
mp	281-284 °C (dec.) (lit.)
SMILES string	N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O
InChI	1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6-/m0/s1
InChI key	ZTVZLYBCZNMWCF-WDSKDSINSA-N

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homoserine

Empirical Formula (Hill Notation):	C₄H₉NO₃
Linear Formula:	HOCH₂CH₂CH(NH₂)CO₂H
CAS Number:	672-15-1
Molecular Weight:	119.12
Beilstein/REAXYS Number:	1721681
EC Number:	211-590-6
MDL number:	MFCD00063090
eCl@ss:	32160406
PubChem Substance ID:	24895748
NACRES:	NA.26

L-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.

10, 250 mg in poly bottle
1, 5 g in poly bottle

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H6515.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,

assay	98% (TLC)
Quality Level	100,
form	powder
application(s)	cell analysis: suitable, detection: suitable
color	white to off-white
mp	203 °C (dec.) (lit.)
SMILES string	N[C@@H](CCO)C(O)=O
InChI	1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChI key	UKAUYVFTDYCKQA-VKHMYHEASA-N

L-Homoserine lactone (HSL), also called acyl-HSL, comprises a homoserine lactone ring and a fatty acyl side. The levels of acyl-HSL in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Homoserine lactone hydrochloride

Empirical Formula (Hill Notation):	C₄H₇NO₂ · HCl
CAS Number:	2185-02-6
Molecular Weight:	137.56
MDL number:	MFCD00058172
PubChem Substance ID:	24895811
NACRES:	NA.26

L-Homoserine lactone hydrochloride has been used as an inhibitor for arterial smooth muscle contraction.

250 mg in poly bottle
1 g in poly bottle

L-Homoserine lactone inhibition reduces virulence factors and halts inflammation and tissue damage. In Pseudomonas aeruginosa it controls virulence factor production and biofilm formation. In Agrobacterium tumefaciens, it is essential for conjugal transfer.
Acylated L-Homoserine lactone(s) are used to study bacterial quorum-sensing signaling mechanisms.

form	powder
Quality Level	200,
application(s)	ligand binding assay: suitable
color	white
storage temp.	20°C
SMILES string	Cl.N[C@H]1CCOC1=O
InChI	1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key	XBKCXPRYTLOQKS-DFWYDOINSA-N

L-Isoleucine has been used in capillary feeder (CAFE) assay in a study to determine the consumption of amino acids by Drosophila melanogaster. It has also been used as one of the components of an amino acid mixture, which is used as a supplement for synthetic complete (SC) media.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Isoleucine

Empirical Formula (Hill Notation):	C₆H₁₃NO₂
Linear Formula:	C₂H₅CH(CH₃)CH(NH₂)CO₂H
CAS Number:	73-32-5
Molecular Weight:	131.17
Beilstein/REAXYS Number:	1721792
EC Number:	200-798-2
MDL number:	MFCD00064222
eCl@ss:	32160406
PubChem Substance ID:	24896006
NACRES:	NA.26

1, 5, 10, 25, 100 g in poly bottle
1 kg in poly bottle

L-Isoleucine is an isomer of L-leucine and is an essential amino acid. It is synthesized from threonine and is a branched-chain hydrophobic amino acid.

grade	reagent grade
Quality Level	200,
assay	98% (HPLC)
form	powder
application(s)	detection: suitable
color	white
mp	288 °C (dec.) (lit.)
solubility	1 M NH4OH: 50 mg/mL
SMILES string	CC[C@H](C)[C@H](N)C(O)=O
InChI	1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
InChI key	AGPKZVBTJJNPAG-WHFBIAKZSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Isoleucine -naphthylamide

Empirical Formula (Hill Notation):	C₁₆H₂₀N₂O
CAS Number:	732-84-3
Molecular Weight:	256.34
MDL number:	MFCD00055912
PubChem Substance ID:	24896063
NACRES:	NA.26

assay	98% (TLC)
Quality Level	200,
form	powder
color	white to off-white
storage temp.	2-8°C
SMILES string	CC[C@H](C)[C@H](N)C(=O)Nc1ccc2ccccc2c1
InChI	1S/C16H20N2O/c1-3-11(2)15(17)16(19)18-14-9-8-12-6-4-5-7-13(12)10-14/h4-11,15H,3,17H2,1-2H3,(H,18,19)/t11-,15-/m0/s1
InChI key	CEZPKIGJZWWHJT-NHYWBVRUSA-N

pictograms	GHS08
signalword	Warning
hcodes	H351
pcodes	P281
Personal Protective Equipment	Eyeshields,, Gloves,, type P1 (EN143) respirator filter,, type P3 (EN 143) respirator cartridges,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Isoserine

Empirical Formula (Hill Notation):	C₃H₇NO₃
CAS Number:	632-13-3
Molecular Weight:	105.09
MDL number:	MFCD03428326
PubChem Substance ID:	329748201
NACRES:	NA.22

Quality Level	100,
assay	98.0% (TLC)
form	powder
reaction suitability	reaction type: solution phase peptide synthesis
application(s)	peptide synthesis: suitable
color	white to off-white
mp	197-198 °C
SMILES string	NC[C@H](O)C(O)=O
InChI	1S/C3H7NO3/c4-1-2(5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChI key	BMYNFMYTOJXKLE-REOHCLBHSA-N

L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Kynurenine

Empirical Formula (Hill Notation):	C₁₀H₁₂N₂O₃
CAS Number:	2922-83-0
Molecular Weight:	208.21
MDL number:	MFCD00069912
PubChem Substance ID:	24896246

L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. It is involved in a variety of neurological processes and diseases. L-Kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.
Key intermediate in the breakdown pathway of tryptophan.

Quality Level	200,
assay	98% (HPLC)
form	powder
application(s)	detection: suitable
color	light yellow
mp	219 °C
SMILES string	N[C@@H](CC(=O)c1ccccc1N)C(O)=O
InChI	1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1
InChI key	YGPSJZOEDVAXAB-QMMMGPOBSA-N

L-Kynurenine sulfate salt has been used as a substrate to study the enzyme activity of kynurenine aminotransferase. It has also been used in the synthesis of Kyn adducts of certain amino acids .

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Kynurenine sulfate salt

Empirical Formula (Hill Notation):	C₁₀H₁₂N₂O₃ · H₂O₄S
Linear Formula:	C₁₀H₁₂N₂O₃ · H₂SO₄
CAS Number:	16055-80-4
Molecular Weight:	306.29
MDL number:	MFCD00039104
PubChem Substance ID:	24896233
NACRES:	NA.26

L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.
L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammals, it modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.
Key intermediate in the breakdown pathway of tryptophan.

assay	98% (HPLC)
Quality Level	200,
form	crystalline
application(s)	ligand binding assay: suitable
color	light yellow
storage temp.	20°C
SMILES string	OS(O)(=O)=O.N[C@@H](CC(=O)c1ccccc1N)C(O)=O
InChI	1S/C10H12N2O3.H2O4S/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15;1-5(2,3)4/h1-4,8H,5,11-12H2,(H,14,15);(H2,1,2,3,4)/t8-;/m0./s1
InChI key	KAXRWMOLNJZCEW-QRPNPIFTSA-N

L-leucine has been used as a hypertrophic agent to monitor its effects on myotubes. It has also been used as a component of PMG media for culturing yeast.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Leucine

Empirical Formula (Hill Notation):	C₆H₁₃NO₂
Linear Formula:	(CH₃)₂CHCH₂CH(NH₂)CO₂H
CAS Number:	61-90-5
Molecular Weight:	131.17
Beilstein/REAXYS Number:	1721722
EC Number:	200-522-0
MDL number:	MFCD00002617
eCl@ss:	32160406
PubChem Substance ID:	24896510
NACRES:	NA.26

10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottle

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

biological source	non-animal source
Quality Level	300,
Agency/Method	USP/NF, meets EP testing specifications, meets JP testing specifications, meets USP testing specifications
assay	98.5-101.0%
form	powder
quality	meets EP, JP, USP testing specifications
application(s)	cell culture \| mammalian: suitable, peptide synthesis: suitable
impurities	endotoxin, tested
color	white
mp	>300 °C (lit.)
solubility	1 M HCl: 50 mg/mL
Featured Industry	Pharmaceutical (small molecule)
SMILES string	CC(C)C[C@H](N)C(O)=O
InChI	1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key	ROHFNLRQFUQHCH-YFKPBYRVSA-N

L-Leucine 3-carboxy-4-hydroxyanilide may be used as a substrate for determining the activity of microsomal aminopeptidase in serum.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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L-Leucine 3-carboxy-4-hydroxyanilide hydrochloride

Empirical Formula (Hill Notation):	C₁₃H₁₈N₂O₄ · HCl
CAS Number:	73801-31-7
Molecular Weight:	302.75
MDL number:	MFCD00058075
PubChem Substance ID:	24896522

application(s)	ligand binding assay: suitable
storage temp.	2-8°C
SMILES string	Cl.CC(C)C[C@H](N)C(=O)Nc1ccc(O)c(c1)C(O)=O
InChI	1S/C13H18N2O4.ClH/c1-7(2)5-10(14)12(17)15-8-3-4-11(16)9(6-8)13(18)19;/h3-4,6-7,10,16H,5,14H2,1-2H3,(H,15,17)(H,18,19);1H/t10-;/m0./s1
InChI key	BSVJWFHAORBGDY-PPHPATTJSA-N

RIDADR	NONH for all modes of transport
WGK Germany	3

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L-Leucine methyl ester hydrochloride

Empirical Formula (Hill Notation):	C₇H₁₅NO₂ · HCl
Linear Formula:	(CH₃)₂CHCH₂CH(NH₂)COOCH₃ · HCl
CAS Number:	7517-19-3
Molecular Weight:	181.66
Beilstein/REAXYS Number:	3595133
EC Number:	231-375-0
MDL number:	MFCD00012494
eCl@ss:	32160406
PubChem Substance ID:	24896269
NACRES:	NA.22

Quality Level	100,
assay	98%
form	powder or crystals
optical activity	[]22/D +13°, c = 2 in H₂O
reaction suitability	reaction type: solution phase peptide synthesis
application(s)	peptide synthesis: suitable
color	white
mp	151-153 °C (lit.)
SMILES string	Cl[H].COC(=O)[C@@H](N)CC(C)C
InChI	1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1
InChI key	DODCBMODXGJOKD-RGMNGODLSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Leucine tert-butyl ester hydrochloride

Empirical Formula (Hill Notation):	C₁₀H₂₁NO₂ · HCl
Linear Formula:	(CH₃)₂CHCH₂CH(NH₂)COOC(CH₃)₃ · HCl
CAS Number:	2748-02-9
Molecular Weight:	223.74
Beilstein/REAXYS Number:	3697141
MDL number:	MFCD00038906
PubChem Substance ID:	24896301
NACRES:	NA.26

assay	98% (TLC)
Quality Level	200,
form	powder
color	white
storage temp.	20°C
SMILES string	Cl.CC(C)C[C@H](N)C(=O)OC(C)(C)C
InChI	1S/C10H21NO2.ClH/c1-7(2)6-8(11)9(12)13-10(3,4)5;/h7-8H,6,11H2,1-5H3;1H/t8-;/m0./s1
InChI key	RFUWRXIYTQGFGA-QRPNPIFTSA-N

L-lysine contains basic side chain and is hydrophilic in nature. The N-butyl amino group in the side chain is found to be protonated at physiological pH. Upon degradation, L-lysine gives ketone bodies. Transamination of lysine with α-ketoglutarate produces acetoacetyl CoA. L-lysine serves as a precursor for secondary metabolites, such as β-lactam antibiotics. It also serves as a precursor for the biosynthesis of α-aminoadipic acid.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine

Empirical Formula (Hill Notation):	C₆H₁₄N₂O₂
Linear Formula:	H₂N(CH₂)₄CH(NH₂)CO₂H
CAS Number:	56-87-1
Molecular Weight:	146.19
Beilstein/REAXYS Number:	1722531
EC Number:	200-294-2
MDL number:	MFCD00064433
eCl@ss:	32160406
PubChem Substance ID:	24896404
NACRES:	NA.26

L-Lysine is an essential proteinogenic amino acid used in a wide range of applications. It has been used:

as a supplement in cell culture media
as a substrate for enzymes such as L-lysine oxidase (EC 1.4.3.14)
as a component of poly-lysine polymers
as a substrate for oxidation and glycation mechanism studies
in the preparation of cobaltous lysine

10 mg in autosample vial
1, 5, 25, 100 g in poly bottle

Quality Level	200
assay	98% (TLC)
form	powder
application(s)	ligand binding assay: suitable
color	white to off-white
mp	215 °C (dec.) (lit.)
solubility	H₂O: soluble
SMILES string	NCCCC[C@H](N)C(O)=O
InChI	1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1
InChI key	KDXKERNSBIXSRK-YFKPBYRVSA-N

25, 100, 500 g in poly bottle

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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L-Lysine acetate salt

Empirical Formula (Hill Notation):	C₆H₁₄N₂O₂ · C₂H₄O₂
CAS Number:	57282-49-2
Molecular Weight:	206.24
EC Number:	260-664-4
MDL number:	MFCD00039069
PubChem Substance ID:	329817395
NACRES:	NA.26

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies.

Quality Level	200,
assay	98% (HPLC)
form	powder
application(s)	ligand binding assay: suitable
color	white
SMILES string	CC(O)=O.NCCCC[C@H](N)C(O)=O
InChI	1S/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m0./s1
InChI key	RRNJROHIFSLGRA-JEDNCBNOSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine dihydrochloride

Empirical Formula (Hill Notation):	C₆H₁₄N₂O₂ · 2HCl
Linear Formula:	NH₂(CH₂)₄CH(NH₂)COOH · 2HCl
CAS Number:	657-26-1
Molecular Weight:	219.11
Beilstein/REAXYS Number:	4539715
EC Number:	211-518-3
MDL number:	MFCD00066389
PubChem Substance ID:	24896413
NACRES:	NA.26

25, 100 g in poly bottle

Quality Level	200,
assay	98% (HPLC)
form	powder
application(s)	ligand binding assay: suitable
color	white to faint yellow
mp	200-206 °C (lit.)
SMILES string	Cl[H].Cl[H].NCCCC[C@H](N)C(O)=O
InChI	1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m0../s1
InChI key	JBBURJFZIMRPCZ-XRIGFGBMSA-N

L-Lysine methyl ester is used in the production of lysine methyl ester based cationic surfactants and hydrogels.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine methyl ester dihydrochloride

Empirical Formula (Hill Notation):	C₇H₁₆N₂O₂ · 2HCl
CAS Number:	26348-70-9
Molecular Weight:	233.14
EC Number:	247-625-7
MDL number:	MFCD00039067
PubChem Substance ID:	24896262
NACRES:	NA.26

assay	99% (TLC)
Quality Level	200,
form	powder
color	white
storage temp.	20°C
SMILES string	Cl.COC(=O)C(N)CCCCN
InChI	1S/C7H16N2O2.ClH/c1-11-7(10)6(9)4-2-3-5-8;/h6H,2-5,8-9H2,1H3;1H
InChI key	FORVAIDSGSLRPX-UHFFFAOYSA-N

L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine monohydrate

Empirical Formula (Hill Notation):	C₆H₁₄N₂O₂ · H₂O
CAS Number:	39665-12-8
Molecular Weight:	164.20
Beilstein/REAXYS Number:	4349963
EC Number:	200-294-2
MDL number:	MFCD00151035
PubChem Substance ID:	24896515

L-Lysine monohydrate has been used in:

SILAC (stable isotope labeling by amino acids in cell culture) method
the complete synthetic (C) medium for positive selection screening of yeast cells
the growth medium for cells

25, 100 g in poly bottle
1 kg in poly bottle

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies.

biological source	non-animal source
Quality Level	200,
product line	BioReagent
assay	98.5-101.5% dry basis
form	crystalline powder
application(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested
color	white
mp	215 °C
solubility	H₂O: soluble
SMILES string	[H]O[H].NCCCC[C@H](N)C(O)=O
InChI	1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1
InChI key	HZRUTVAFDWTKGD-JEDNCBNOSA-N

L-lysine monohydrochloride has been used:

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine monohydrochloride

Empirical Formula (Hill Notation):	C₆H₁₄N₂O₂ · HCl
Linear Formula:	H₂N(CH₂)₄CH(NH₂)CO₂H·HCl
CAS Number:	657-27-2
Molecular Weight:	182.65
Beilstein/REAXYS Number:	3563889
EC Number:	211-519-9
MDL number:	MFCD00064564
PubChem Substance ID:	24896408
NACRES:	NA.26

as a component in pre-fixative solution for electron microscopy
as a component in blocking solution for immunohistochemistry(IHC)
in the preparation of Periodate-lysine-paraformaldehyde (PLP) fixative for IHC

1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

grade	reagent grade
Quality Level	200,
assay	98% (HPLC)
form	powder
application(s)	immunohistochemistry: suitable, peptide synthesis: suitable
color	white to off-white
mp	263 °C (dec.) (lit.)
SMILES string	OC([C@@H](N)CCCCN)=O.[H]Cl
InChI	1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1
InChI key	BVHLGVCQOALMSV-JEDNCBNOSA-N

L-Lysine p-nitroanilide may be used as a substrate to study the specificity and kinetics of lysine aminopeptidase(s) and various proteinases.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Lysine p-nitroanilide dihydrobromide

Empirical Formula (Hill Notation):	C₁₂H₁₈N₄O₃ · 2HBr
CAS Number:	40492-96-4
Molecular Weight:	428.12
MDL number:	MFCD00050686
PubChem Substance ID:	24896389
NACRES:	NA.26

assay	98% (TLC)
Quality Level	200,
form	powder
application(s)	ligand binding assay: suitable
color	off-white
storage temp.	2-8°C
SMILES string	Br.NCCCC[C@H](N)C(=O)Nc1ccc(cc1)N(=O)=O
InChI	1S/C12H18N4O3.BrH/c13-8-2-1-3-11(14)12(17)15-9-4-6-10(7-5-9)16(18)19;/h4-7,11H,1-3,8,13-14H2,(H,15,17);1H/t11-;/m0./s1
InChI key	FJNCJWJSSUJZMS-MERQFXBCSA-N

L-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Methionine

Empirical Formula (Hill Notation):	C₅H₁₁NO₂S
Linear Formula:	CH₃SCH₂CH₂CH(NH₂)CO₂H
CAS Number:	63-68-3
Molecular Weight:	149.21
Beilstein/REAXYS Number:	1722294
EC Number:	200-562-9
MDL number:	MFCD00063097
eCl@ss:	32160406
PubChem Substance ID:	24897343
NACRES:	NA.26

5, 25, 100, 500 g in poly bottle
1 kg in poly bottle

L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionines metabolic product, glutathione, is known to regulate immune response and has antiviral action.

Quality Level	200
grade	reagent grade
assay	98% (HPLC)
form	powder
application(s)	detection: suitable
color	white
mp	284 °C (dec.) (lit.)
SMILES string	CSCC[C@H](N)C(O)=O
InChI	1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key	FFEARJCKVFRZRR-BYPYZUCNSA-N
Gene Information	rat ... Ggt1(116568)

100 mg in poly bottle
1 g in poly bottle

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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L-Methionine p-nitroanilide

Empirical Formula (Hill Notation):	C₁₁H₁₅N₃O₃S
CAS Number:	6042-04-2
Molecular Weight:	269.32
MDL number:	MFCD00063424
PubChem Substance ID:	24896851
NACRES:	NA.26

L-Methionine p-nitroanilide is a hMetAP2 substrate.

assay	98% (TLC)
Quality Level	200,
form	powder
application(s)	ligand binding assay: suitable
color	white to faint yellow
storage temp.	20°C
SMILES string	CSCC[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI	1S/C11H15N3O3S/c1-18-7-6-10(12)11(15)13-8-2-4-9(5-3-8)14(16)17/h2-5,10H,6-7,12H2,1H3,(H,13,15)/t10-/m0/s1
InChI key	PLBWRAWSHVJPTL-JTQLQIEISA-N

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Methionine sulfone

Empirical Formula (Hill Notation):	C₅H₁₁NO₄S
CAS Number:	7314-32-1
Molecular Weight:	181.21
Beilstein/REAXYS Number:	1725510
EC Number:	230-774-7
MDL number:	MFCD00066020
PubChem Substance ID:	24896574
NACRES:	NA.26

L-Methionine sulfone may be used to study pupae development of the silkworm Bombyx mori L. L-Methionine sulfone may be used as a complexing agent to study conformational structures and stereospecificity of enzymes such as glutamate synthase and gamma-glutamyl transpeptidase.

assay	98% (TLC)
Quality Level	200,
form	powder or crystals
application(s)	detection: suitable, peptide synthesis: suitable
color	white
mp	275 °C
SMILES string	CS(=O)(=O)CC[C@H](N)C(O)=O
InChI	1S/C5H11NO4S/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key	UCUNFLYVYCGDHP-BYPYZUCNSA-N
Gene Information	rat ... Ggt1(116568)

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Methionine sulfoxide

Empirical Formula (Hill Notation):	C₅H₁₁NO₃S
CAS Number:	3226-65-1
Molecular Weight:	165.21
Beilstein/REAXYS Number:	4129939
EC Number:	221-758-0
MDL number:	MFCD00063093
PubChem Substance ID:	24896617
NACRES:	NA.26

L-Methionine sulfoxide, a structural analog of glutamate, may be used as a substrate to study the specificity and kinetics of various methionine sulfoxide reductase(s).

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M1126.pdf, Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,

assay	98% (TLC)
Quality Level	200,
form	powder
application(s)	detection: suitable, peptide synthesis: suitable
color	white to off-white
mp	255 °C
SMILES string	CS(=O)CC[C@H](N)C(O)=O
InChI	1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m0/s1
InChI key	QEFRNWWLZKMPFJ-YGVKFDHGSA-N
Gene Information	rat ... Ggt1(116568)

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P305 + P351 + P338
Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Norleucine N8513-100MG

Empirical Formula (Hill Notation):	C₆H₁₃NO₂
Linear Formula:	CH₃(CH₂)₃CH(NH₂)CO₂H
CAS Number:	327-57-1
Molecular Weight:	131.17
Beilstein/REAXYS Number:	1721750
EC Number:	206-321-4
MDL number:	MFCD00064423
eCl@ss:	32160406
PubChem Substance ID:	24897682
NACRES:	NA.26

Highly purified internal standard for all amino acid analysis methods.

Non-essential amino acid.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N8513.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,

Quality Level	200,
product line	BioReagent
form	powder or crystals
application(s)	detection: suitable
color	white
mp	>300 °C (lit.)
suitability	suitable for amino acid analysis
SMILES string	CCCC[C@H](N)C(O)=O
InChI	1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChI key	LRQKBLKVPFOOQJ-YFKPBYRVSA-N

1, 5, 10 g in poly bottle

Personal Protective Equipment	dust mask type N95 (US),, Eyeshields,, Faceshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

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L-Norleucine

Empirical Formula (Hill Notation):	C₆H₁₃NO₂
Linear Formula:	CH₃(CH₂)₃CH(NH₂)CO₂H
CAS Number:	327-57-1
Molecular Weight:	131.17
Beilstein/REAXYS Number:	1721750
EC Number:	206-321-4
MDL number:	MFCD00064423
eCl@ss:	32160406
PubChem Substance ID:	24897796
NACRES:	NA.26

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Non-essential amino acid.

Quality Level	200,
assay	98% (TLC)
form	powder
application(s)	detection: suitable
color	white
mp	>300 °C (lit.)
SMILES string	CCCC[C@H](N)C(O)=O
InChI	1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChI key	LRQKBLKVPFOOQJ-YFKPBYRVSA-N

1, 5, 10 g in poly bottle

pictograms	GHS07
signalword	Warning
hcodes	H317
pcodes	P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
Personal Protective Equipment	dust mask type N95 (US),, Eyeshields,, Faceshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Norvaline

Empirical Formula (Hill Notation):	C₅H₁₁NO₂
Linear Formula:	CH₃CH₂CH₂CH(NH₂)CO₂H
CAS Number:	6600-40-4
Molecular Weight:	117.15
Beilstein/REAXYS Number:	1721162
EC Number:	229-543-3
MDL number:	MFCD00064421
eCl@ss:	32160406
PubChem Substance ID:	24897833
NACRES:	NA.26

L-Norvaline enhances NO production from activated macrophages.

Quality Level	200,
assay	99% (TLC)
form	powder
application(s)	detection: suitable
color	white
mp	>300 °C (lit.)
SMILES string	CCC[C@H](N)C(O)=O
InChI	1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key	SNDPXSYFESPGGJ-BYPYZUCNSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Ornithine dihydrochloride

Empirical Formula (Hill Notation):	C₅H₁₂N₂O₂ · 2HCl
CAS Number:	6211-16-1
Molecular Weight:	205.08
Beilstein/REAXYS Number:	4538819
EC Number:	228-277-5
MDL number:	MFCD00066571
PubChem Substance ID:	329766423
NACRES:	NA.26

L-Ornithine is a non-proteinogenic recycled component of the Urea Cycle leading to the production of arginine. L-ornithine is the starting compound for polyamine biosynthesis via ornithine decarboxylase.

Quality Level	100,
assay	99.0% (AT)
form	crystals
optical activity	[]20/D +17±1°, c = 5% in H₂O
application(s)	ligand binding assay: suitable
ign. residue	0.1% (as SO₄)
color	colorless
mp	197-199 °C (dec.)
anion traces	sulfate (SO₄^2-): 100 mg/kg
cation traces	As: 0.1 mg/kg, Cd: 5 mg/kg, Co: 5 mg/kg, Cu: 5 mg/kg, Fe: 5 mg/kg, NH₄⁺: 100 mg/kg, Ni: 5 mg/kg, Pb: 5 mg/kg, Zn: 5 mg/kg
SMILES string	Cl.Cl.NCCC[C@H](N)C(O)=O
InChI	1S/C5H12N2O2.2ClH/c6-3-1-2-4(7)5(8)9;;/h4H,1-3,6-7H2,(H,8,9);2*1H/t4-;;/m0../s1
InChI key	HGBAVEGDXFHRQP-FHNDMYTFSA-N

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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L-Ornithine L-aspartate salt

Empirical Formula (Hill Notation):	C₉H₁₉N₃O₆
CAS Number:	3230-94-2
Molecular Weight:	265.26
EC Number:	221-772-7
MDL number:	MFCD00058084
PubChem Substance ID:	329818920
NACRES:	NA.26

25, 100 g in poly bottle

L-Ornithine L-aspartate is a metabolite of arginine degradation by arginase. It has been shown to reduce blood ammonia concentrations by increasing ammoniadetoxification in the muscle and reducing the severity of hepatic encephalopathy in cirrhosis.

Product of arginine degradation by arginase

assay	98% (TLC)
Quality Level	200,
form	powder
color	white to off-white
storage temp.	2-8°C
SMILES string	NCCC[C@H](N)C(O)=O.N[C@@H](CC(O)=O)C(O)=O
InChI	1S/C5H12N2O2.C4H7NO4/c6-3-1-2-4(7)5(8)9;5-2(4(8)9)1-3(6)7/h4H,1-3,6-7H2,(H,8,9);2H,1,5H2,(H,6,7)(H,8,9)/t4-;2-/m00/s1
InChI key	IXUZXIMQZIMPSQ-ZBRNBAAYSA-N