Anti-Horse IgG (whole molecule)FITC antibody produced in rabbit

MDL number:	MFCD00163518
NACRES:	NA.46

Кат. номер

F7759-2ML

F7759-.5ML

F7759-1ML

Horse IgG is a plasma B cell derived antibody isotype defined by its heavy chain. IgG is the most abundant antibody isotype found in horse serum. IgG crosses the placental barrier, is a complement activator and binds to the Fc-receptors on phagocytic cells. The level of IgG may vary with the status of disease or infection.
An immunoglobulin has two heavy chains and two light chains connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Horse IgG has different subclasses, IgG2a, IgG2b, IgG2c, IgG1 and IgG(T). Compared to other IgG molecules, IgG(T) has more carbohydrate content. In healthy individuals, total IgG is dispersed equally between circulating plasma and interstitial fluids.
Specificity
Anti-horse IgG (whole molecule)-FITC antibody is specific for horse IgG subclasses.
Purified horse IgG
Anti-Horse IgG (whole molecule) FITC antibody produced in rabbit has been used in indirect fluorescent antibody test. It has also been used as a secondary antibody to confirm equine arteritis virus (EAV).
Rabbit polyclonal anti-Horse IgG (whole molecule)FITC antibody may be used to detect and quantitate the level of IgG in horse serum and biological fluids by fluorescent techniques. It may also be used as a secondary antibody in assays that use horse IgG as the primary antibody.
Biochem/physiol Actions
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. It mainly helps in immune defense.
IgG antibody subtype is the most abundant serum immunoglobulin of the immune system. It is secreted by B- cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to the fetus through the placenta that is vital for immune defense of the neonate against infections.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
Storage and Stability
For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source	rabbit
Quality Level	200,
antibody form	affinity isolated antibody
antibody product type	secondary antibodies
clone	polyclonal
form	buffered aqueous solution
storage condition	protect from light
application(s)	direct immunofluorescence: suitable
conjugate	FITC conjugate
storage temp.	−20°C

Personal Protective Equipment	Eyeshields,, Gloves,, multi-purpose combination respirator cartridge (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable