Hydroxychloroquine Sulfate
Empirical Formula (Hill Notation): | C18H26ClN3O · H2SO4 |
CAS Number: | 747-36-4 |
Molecular Weight: | 433.95 |
EC Number: | 212-019-3 |
MDL number: | MFCD00078203 |
PubChem Substance ID: | 329823611 |
NACRES: | NA.24 |
Кат. номер |
PHR1782-1G |
PHR1782-1G-PW |
Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Hydroxychloroquine Sulfate can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0287 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
biological source | synthetic |
grade | certified reference material, pharmaceutical secondary standard |
Agency/Method | BP, EP, USP |
form | powder or crystals |
CofA | current certificate can be downloaded |
packaging | pkg of 1 g |
storage condition | protect from light |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
color | white to off-white |
pH | 3.5-5.5 (1% in aqueous solution, pH <6.0) |
mp | 238-241 °C |
solubility | chloroform: practically insoluble, ethanol: practically insoluble, ether: practically insoluble, water: soluble |
Featured Industry | Pharmaceutical (small molecule) |
pharmacopeia traceability | traceable to BP 1100, traceable to USP 1327000 |
shipped in | ambient |
SMILES string | OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 |
InChI | 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4) |
InChI key | JCBIVZZPXRZKTI-UHFFFAOYSA-N |
Gene Information | human ... TLR7(51284), TLR9(54106) |
pictograms | GHS07 |
signalword | Warning |
hcodes | H302 - H315 - H319 |
pcodes | P301 + P312 + P330 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |