Tetracycline hydrochloride 1651009-200MG
Empirical Formula (Hill Notation): | C22H24N2O8 · HCl |
CAS Number: | 64-75-5 |
Molecular Weight: | 480.90 |
Beilstein/REAXYS Number: | 3844873 |
MDL number: | MFCD00078142 |
PubChem Substance ID: | 329751256 |
NACRES: | NA.24 |
This product is provided as delivered and specified by the issuing Pharmacopoeia. Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.
Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.
Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
USP issued SDS can be found here.
Sales restrictions may apply.
grade | pharmaceutical primary standard |
Торговая марка | USP |
mp | 220-223 °C (lit.) |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
storage temp. | 2-8°C |
SMILES string | Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O |
InChI | 1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1 |
InChI key | XMEVHPAGJVLHIG-FMZCEJRJSA-N |
pictograms | GHS08,GHS09 |
signalword | Warning |
hcodes | H361d - H411 |
pcodes | P201 - P273 - P308 + P313 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 2 |