Cycloserine
Empirical Formula (Hill Notation): | C3H6N2O2 |
CAS Number: | 68-41-7 |
Molecular Weight: | 102.09 |
Beilstein/REAXYS Number: | 80798 |
EC Number: | 200-688-4 |
MDL number: | MFCD00005353 |
Кат. номер |
PHR1765-1G |
PHR1765-1G-PW |
Cycloserine is a broad-spectrum antibiotic commonly produced by certain strains of
Streptomyces orchidaceus or
S. garphalus. It is used as a second-line drug treatment for multiple drug-resistant strains of
Mycobacterium tuberculosis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cycloserine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8432 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
grade | certified reference material, pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
packaging | pkg of 1 g |
mp | 147 °C (dec.) (lit.) |
Featured Industry | Pharmaceutical |
format | neat |
pharmacopeia traceability | traceable to USP 1158005 |
SMILES string | N[C@@H]1CONC1=O |
InChI | 1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1 |
InChI key | DYDCUQKUCUHJBH-UWTATZPHSA-N |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |