SILu™Lite APOA2 Apolipoprotein A-II human

NACRES:

NA.12

Кат. номер

MSST0030-50UG

MSST0030-50UG-PW

Apolipoprotein A-II (ApoA-II) occurs in plasma as a dimer of two 77-amino acid chains linked by a disulfide bridge. After apoA-I, it is the second major protein component of HDL, accounting for approximately 20% of HDL total protein. ApoA-II is thought to play an important role in triglyceride metabolism both from animal and human studies. 3 Recent findings attribute apoA-II to inhibitory effects on lipoprotein lipase-mediated hydrolysis of triglyceride-rich particles. Additional associations of apoA-II have been reported for a variety of protein factors including hepatic lipase (HL), lipoprotein lipase (LPL), endothelial lipase, CETP, PLTP, and LCAT.
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGLDRIRGRKLGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite APOA2 is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 97 amino acids (including C-terminal polyhistidine and flag tags), with a calculated molecular mass of 11 kDa. SILu Lite APOA2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.
SILu is a trademark of Sigma-Aldrich Co. LLC

Quality Level	200
biological source	human
recombinant	expressed in HEK 293 cells
assay	98% (SDS-PAGE)
form	lyophilized powder
potency	98 Heavy amino acids incorporation efficiency by MS
application(s)	mass spectrometry (MS): suitable
suitability	suitable for mass spectrometry (internal calibrator)
UniProt accession no.	P02652,
storage temp.	20°C
Gene Information	human ... APOA2(336)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable