MultiScreen Permeability Filter Plate, 0.4 µm, non-sterile MPC4NTR10

eCl@ss:	32039006
NACRES:	NB.22

Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
Filter Code: PCF
Research Category
Assays
Protein
Color Code: Clear
Automation Compatible: No
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

Quality Level	400,
material	flat bottom wells, polycarbonate membrane, polystyrene
sterility	non-sterile
product line	MultiScreen®
feature	lid
Торговая марка	MultiScreen®
application(s)	DNA purification: suitable, activity assay: suitable (with precipitations), ligand binding assay: suitable, parallel artificial membrane permeation assay (PAMPA): suitable, receptor binding assay: suitable, sample preparation: suitable
plate size	96 wells
well maximum volume	300 µL
working volume	125 µL
pore size	0.4 µm pore size
test parameters	sample volume: 100 µL (per well)
shipped in	ambient