AST Activity Assay Kit MAK055-1KT

NACRES:

NA.84

Aspartate Aminotransferase (AST), formerly called serum glutamate-oxaloacetate transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the conversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate. Similar to Alanine Aminotransferase (ALT), AST levels in blood are commonly used as a marker for liver function. However, AST has a broader tissue distribution than ALT and perturbations in AST levels can occur in response to diseases or injuries in multiple tissues including skeletal and heart.
AST Activity Assay Kit has been used to determine the activity of aspartate aminotransferase in samples.
Compatible with high-throughput handling systems.
Suitable for the measurement of aspartate aminotransferase (AST) activity in biological samples including tissue, cells and serum
The Aspartate Aminotransferase Activity Assay kit provides a simple and direct procedure for measuring AST activity in a variety of samples. In this kit, the transfer of an amino group from aspartate to α-ketoglutarate results in the generation of glutamate, resulting in the production of a colorimetric (450 nm) product proportional to the AST enzymatic activity present. One unit of AST is the amount of enzyme that will generate 1.0 μmole of glutamate per minute at pH 8.0 at 37 °C.

usage	sufficient for 100 colorimetric tests
detection method	colorimetric
storage temp.	20°C
Gene Information	human ... GOT1(2805) mouse ... GOT1(14718) rat ... GOT1(24401)

Pictograms	GHS07,GHS09
Signal Word	Warning
Hazard Statements	H335 - H411
Precautionary Statements	P261 - P271 - P273 - P304 + P340 + P312 - P391 - P403 + P233
Target Organs	Respiratory system
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3