Rhodamine 123

Empirical Formula (Hill Notation):	C21H16N2O3 · HCl
Linear Formula:	C21H17ClN2O3
CAS Number:	62669-70-9
Molecular Weight:	380.82
Beilstein/REAXYS Number:	6030951
EC Number:	263-687-8
MDL number:	MFCD00012664
PubChem Substance ID:	24899403
NACRES:	NA.47

Кат. номер

R8004-100MG

R8004-5MG

R8004-25MG

Rhodamine 123 is useful as a laser dye and to have selective cell growth effects. It has also been used to measure mitochondrial membrane potential.
5, 25, 100 mg in glass bottle
Rhodamine 123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for P-glycoprotein (Pgp). It is part of the rhodamine family of flurone dyes. The dye is mostly used to assess mitochondrial bioenergetics in living cells. Functional assays for multi-drug resistance (MDR) proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of multi-drug resistance protein-1 (MRP1).
Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of MRP1.

Quality Level	100,
form	powder
application(s)	hematology: suitable, histology: suitable
solubility	ethanol: 1 mg/mL
Featured Industry	Diagnostic Assay Manufacturing
storage temp.	room temp
SMILES string	Cl[H].COC(=O)c1ccccc1C2=C3C=CC(=N)C=C3Oc4cc(N)ccc24
InChI	1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H
InChI key	MYFATKRONKHHQL-UHFFFAOYSA-N

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable