Astec® CHIRALDEX® G-TA Capillary GC Column 73033AST

NACRES:

SB.54

Astec® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.
Astec® CHIRALDEX® G-TA (2,6-di-O-pentyl-3-trifluoroacetyl--cyclodextrin) derivatized cyclodextrin chiral stationary phase may be used in capillary gas chromatography for separation of four isomers from 7 racemic sulfinate esters. It was used in an experimental study done for cloning and characterization of three epoxide hydrolases identified by analyzing open reading frames (ORFs) of a marine bacterium, Erythrobacter litoralis HTCC2594. It was also used in HPLC and GC analyses of the conversion of epoxides during enantioselectivity of epoxide hydrolase from Agrobacterium radiobacter (EchA) using error-prone PCR and DNA shuffling.
Temp. Limits:

• -10 °C to 180 °C isothermal and programmed

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Astec is a registered trademark of Sigma-Aldrich Co. LLC
CHIRALDEX is a registered trademark of Sigma-Aldrich Co. LLC

Quality Level	100
material	fused silica
description	GC capillary column
packaging	pkg of 1 ea
parameter	-10-180 °C temperature (isothermal or programmed)
Beta value	500
df	0.12 µm
application(s)	gas chromatography (GC): suitable
L x I.D.	30 m x 0.25 mm
matrix active group	non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of -cyclodextrin phase
Featured Industry	Agriculture Chemicals and Industrial Polymers Cleaning Products Clinical Cosmetics Environmental Flavors and Fragrances Food and Beverages Forensics and Toxicology Life Science and Biopharma Personal Care Pharmaceutical (small molecule)
column type	capillary chiral
separation technique	chiral