Human soluble TNF Receptor 2 ELISA Kit RAB0490-1KT

NACRES:

NA.32

The Human sTNF RII ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human sTNF RII in serum, plasma, cell culture supernatants and urine.
Recombinant Human TNF RII
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure ,(sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Tumor necrosis factor receptor 2 (TNFR2) plays a vital role in inducing signals for various cellular process, including proliferation of thymocytes and peripheral T cells, T cell secretion of granulocyte-macrophage colony-stimulating factor, inhibition of early hematopoiesis, and the inactivation and clearance of TNF by the kidney. Mutation in the gene leads to hematopoietic cell malignancies, neuroblastoma, glioma, cervical and ovarian carcinoma. TRAF2 interacts with TNFR2 and activates NF-kappa B (NF-κB) pathway. TNFR2, which lacks death domains, modulates the effect of other death receptor TNFR1, which induces T cell death. TNFR2 plays an essential role in TNF-α–induced leukocyte-endothelial interaction. TNFR2 is considered as a potential therapeutic alternative, as it has capacity to nullify the common side effects associated with drugs targeting TNF-α or p55.
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

species reactivity	human
packaging	kit of 96 wells (12 strips x 8 wells)
application(s)	ELISA: suitable, capture ELISA: suitable
input	sample type plasma sample type serum sample type plasma sample type serum sample type cell culture supernatant(s) sample type urine
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 5 pg/mL standard curve range: 2.74-2000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	20°C

pictograms	GHS05
signalword	Warning
hcodes	H290
RIDADR	UN 3264 8 / PGIII