Human Platelet Factor-4 / CXCL4 ELISA Kit RAB0402-1KT

NACRES:

NA.32

The Human PF-4 (Platelet Factor-4) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PF-4 in serum, plasma, cell culture supernatants and urine.
Recombinant Human PF4
Human Platelet Factor-4 / CXCL4 ELISA Kit has also been used in the measurement of platelet factor-4 in serum samples of prostate cancer and pseudoxanthoma elasticum patients.
For research use only. Not for use in diagnostic procedures.
Human Platelet Factor-4 (PF4)/ CXCL4 (chemokine (C-X-C motif) ligand 4) ELISA Kit has been used to measure PF-4 / CXCL4 serum level in chronic myelomonocytic leukemia (CMML) patients.
Biochem/physiol Actions
Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various other negatively charged proteoglycans. PF-4 / CXCL4 is implicated in cancer development. PF-4 regulates the activity of proangiogenic growth factors. PF-4 / CXCL4 function as a biomarker for systemic sclerosis and early tumor growth. PF-4 / CXCL4 is associated with various pathological conditions such as atherosclerosis, liver fibrosis and inflammation.
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

species reactivity	human
packaging	kit of 96 wells (12 strips x 8 wells)
application(s)	ELISA: suitable, capture ELISA: suitable
input	sample type serum sample type plasma sample type urine sample type cell culture supernatant(s)
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 20 pg/mL standard curve range: 20.58-15000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	20°C
Gene Information	human ... PF4(5196)

pictograms	GHS05
signalword	Warning
hcodes	H290
RIDADR	UN 3264 8 / PGIII