Human IL-10 ELISA Kit RAB0244-1KT

NACRES:

NA.32

Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells and B cells. Murine IL-10 is inactive on human cells. The gene encoding this protein is localized on human chromosome 1q31-32.
Recombinant Human IL-10
Human IL-10 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to detect interleukin-10 (IL-10) in the plasma of uremic patients undergoing hemodialysis (HD).
For research use only. Not for use in diagnostic procedures.
Human IL-10 ELISA kit has been used for determining the levels of IL-10 in cell culture supernatant.
Biochem/physiol Actions
IL-10 (interleukin 10) is an anti-inflammatory cytokine. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF (tumor necrosis factor)-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Polymorphisms in the IL-10 gene are associated with higher risk of preeclampsia, ankylosing spondylitis, nasopharyngeal carcinoma and basal cell carcinoma. Polymorphism in IL-10 at -1082A/G is associated with diabetic nephropathy.
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species reactivity	human
packaging	kit of 96 wells (12 strips x 8 wells)
application(s)	ELISA: suitable, capture ELISA: suitable
input	sample type urine sample type cell culture supernatant(s) sample type serum sample type plasma
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 1 pg/mL standard curve range: 2.34-150 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	20°C
Gene Information	human ... IL10(3586)

pictograms	GHS05
signalword	Warning
hcodes	H290
RIDADR	UN 3264 8 / PGIII