Human DPPIV / CD26 ELISA Kit RAB0147-1KT

NACRES:

NA.32

The Human CD26 (also known as DPPIV) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD26 in serum, plasma, cell culture supernatants and urine.
Recombinant Human CD26
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure ,(sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Dipeptidyl peptidase 4 (DPPIV), also known as CD26 (cluster of differentiation 26), is localized on T- cell surface and interacts with adenosine deaminase (ADA), collagen and CD459. It plays a vital role in T cell co-stimulation, cell-to-cell adhesion, and in human immunodeficiency virus (HIV) infection. Deletion of the DPPIV gene alters carbohydrate metabolism which in turn leads to mental retardation and hypotonia. Abnormal expression of DPPIV is observed during liver regeneration, human cirrhosis and liver tumorigenesis. DPPIV level is reduced in serum of chronic obstructive pulmonary disease (COPD) patients, hence, this protein has potential as a serologic marker for screening COPD. DPP4 functions as a serine protease enzyme that catalyzes the cleavage of dipeptides from peptides containing proline or alanine residues. IL-13 induced DPPIV expression is upregulated in bronchial epithelial cells (BECs) and this expression might contribute to the development of asthmatic airway inflammation, cell proliferation and fibronectin (FN) production. This protein is a promising biomarker and therapeutic target for asthma.
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

species reactivity	human
packaging	kit of 96 wells (12 strips x 8 wells)
application(s)	ELISA: suitable, capture ELISA: suitable
input	sample type urine sample type plasma sample type serum sample type cell culture supernatant(s)
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 25 pg/mL standard curve range: 32.77-8000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	20°C
Gene Information	human ... DPP4(1803)

pictograms	GHS05
signalword	Warning
hcodes	H290
RIDADR	UN 3264 8 / PGIII