Atrial Natriuretic Peptide EIA Kit RAB0385-1KT

NACRES:

NA.32

The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity.
Atrial Natriuretic Peptide, synthetic peptide
For research use only. Not for use in diagnostic procedures.
Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients.
Atrial Natriuretic Peptide EIA Kit has been used for the quantification of atrial natriuretic peptide (ANP) in cell culture.
Biochem/physiol Actions
Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality.

species reactivity	rat, human, mouse
packaging	kit of 96 wells (12 strips x 8 wells)
application(s)	ELISA: suitable, enzyme immunoassay: suitable
input	sample type plasma sample type serum sample type cell lysate sample type culture supernatant(s)
assay range	inter-assay cv: <15% intra-assay cv: <10% sensitivity: 1.02 pg/mL standard curve range: 0.1-1000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	20°C
Gene Information	human ... NPPA(4878)

pictograms	GHS05
signalword	Warning
hcodes	H290
RIDADR	UN 3264 8 / PGIII