Propyl gallate for ID and assay Y0002116
Empirical Formula (Hill Notation): | C10H12O5 |
Linear Formula: | 3,4,5-(HO)3C6H2CO2CH2CH2CH3 |
CAS Number: | 121-79-9 |
Molecular Weight: | 212.20 |
Beilstein/REAXYS Number: | 1877976 |
MDL number: | MFCD00002196 |
This product is provided as delivered and specified by the issuing Pharmacopoeia. Used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both
in vitro and
in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both
in vitro and
in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 µM when it was combined with copper concentrations at 5 µM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Unit quantity: 80 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. Prepare a 0.1M solution in glycerol:PBS (9:1)
Sales restrictions may apply.
Торговая марка | EDQM |
mp | 146-149 °C (lit.) |
storage temp. | 2-8°C |
SMILES string | CCCOC(=O)c1cc(O)c(O)c(O)c1 |
InChI | 1S/C10H12O5/c1-2-3-15-10(14)6-4-7(11)9(13)8(12)5-6/h4-5,11-13H,2-3H2,1H3 |
InChI key | ZTHYODDOHIVTJV-UHFFFAOYSA-N |
pictograms | GHS05,GHS07,GHS09 |
signalword | Danger |
hcodes | H302 - H317 - H318 - H410 |
pcodes | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
WGK Germany | WGK 2 |
Flash Point F | 368.6 °F - closed cup |
Flash Point C | 187 °C - closed cup |