-Glucuronidase from bovine liver

CAS Number:	9001-45-0
Enzyme Commission (EC) Number:	3.2.1.31 ( BRENDA | IUBMB )
EC Number:	232-606-8
MDL number:	MFCD00130629

Кат. номер

G0251-100KU

G0251-1MU

G0251-CP

G0251-5MU

G0251-500KU

β-Glucuronidase (GUSB) is a lysosomal enzyme, found in animals, plants and bacteria. This exoglycosidase shows high activity in spleen, liver and kidney. Bovine liver β-glucuronidase (BLG) is homotetramer with a molecular weight of 290 kDa.
β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression.
-Glucuronidase from bovine liver has been used in -glucuronidase inhibition assay to study the -glucuronidase inhibitory effect of extracts and isolated actives from Phyllanthus amarus. It has also been used to perform deglucuronidation.
100000, 500000, 1000000, 5000000 units in poly bottle
β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption.
β-Glucuronidase (GUSB) deficiency can result in mucopolysaccharidosis type VII (MPSVII), which leads to store lysosome in the brain. Integration of β-glucuronides of steroid hormones into tissues can be done with the help of GUSB.
One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 5.0 (30 min assay).

Quality Level	200
type	Type B-1
form	solid
specific activity	≥1,000,000 units/g solid
storage temp.	−20°C

pictograms	GHS08
signalword	Danger
hcodes	H317 - H334
pcodes	P280 - P302 + P352
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable