Urea

Empirical Formula (Hill Notation):	CH4N2O
Linear Formula:	NH2CONH2
CAS Number:	57-13-6
Molecular Weight:	60.06
Beilstein/REAXYS Number:	635724
MDL number:	MFCD00008022
EC Index Number:	200-315-5

Кат. номер
1370309800
1370309012BWT
1370309526
1370300000
1370309012
1370305000
1370309026
1370309029
1370309150
1370309999
1370309100
1.37030.9012
1.37030.9012.BWT
1.37030.9029
1.37030.5000

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Urea is typically used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. It is useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. Urea may be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Due to its low microbial and endotoxin limits, Urea cryst. Emprove® Expert is especially suitable for high-risk applications.
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

storage conditions	Store at +15°C to +30°C.
Quality Level	500,
grade	ACS reagent
Agency/Method	BP, JP, Ph. Eur., USP
vapor pressure	<0.1 hPa ( 20 °C)
product line	EMPROVE® EXPERT
assay	98.0-102.0% (HPLC)
potency	8471 mg/kg LD50, oral (Rat), 8200 mg/kg LD50, skin (Rat)
pH	9 (20 °C, 100 g/L in H2O)
mp	132-135 °C (lit.)
density	1.335 g/mL at 25 °C (lit.)
bulk density	720760 kg/m3
storage temp.	2-30°C
SMILES string	NC(N)=O
InChI	1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key	XSQUKJJJFZCRTK-UHFFFAOYSA-N