Benzonase® endonuclease Safety Plus Emprove® Expert

Кат. номер

1037730001

1037731010

1037730010

Benzonase® endonuclease Safety Plus Emprove® Expert is a companion product to our existing Benzonase® portfolio. All Benzonase® endonuclease products share the same amino acid sequence (proven by LC-MS/MS mass spectrometry), robustness and activity. Acting as endonuclease, degrading both DNA and RNA to small 3–5 base pairs (<6 kDa) fragments with no base preference, they are the ideal tool for nucleic acid removal in virus vector and vaccine manufacturing as demanded by the regulators. The use of Benzonase® endonuclease additionally increases the yield in virus purification, protects the downstream chromatography and filter devices from fouling and reduces feed stream viscosity. With its new features, Benzonase® endonuclease Safety Plus Emprove® Expert is ideally suited for manufacturing of cell and gene therapy agents such as adeno associated and lenti viruses, oncolytic viruses and viral vector vaccines.
DNA clearance for purification of biopharmaceuticals, viral vaccines, viral vector vaccines, viral vectros for cell and gene therapy applications as well as oncolytic viruses.
Packaging

• 100,000 Units
• 500,000 Units
• 5,000,000 Units + 50,000 Units tailgate sample

Preparation Note
Benzonase® endonuclease Safety Plus Emprove® Expert is manufactured under good manufacturing practices (GMP ICH Q7)
Benzonase is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Quality Level	500,
sterility	non-sterile
product line	EMPROVE® EXPERT
feature	autoclavable: no
impurities	0.25 EU/kU bacterial endotoxins
shipped in	dry ice
storage temp.	20°C

WGK Germany

WGK 1