Chemistry & Biochemicals
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Fmoc-Arg(Pbf)-OPfp
Empirical Formula (Hill Notation): C40H39F5N4O7S CAS Number: 200132-16-7 Molecular Weight: 814.82 MDL number: MFCD00237040
Кат. номер 8521340100 8521340025 8521340005 8.52134.0005 General descriptionThe product number for this product was previously 04-12-1544.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1544Analysis NoteColor (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0% (a/a)
Purity (TLC (0003)): <2% DCU
Assay (HPLC, area%): 90.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 90.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Arg(Pbf)-Wang resin
MDL number: MFCD01867678 PubChem Substance ID: 57650933 NACRES: NA.26
Кат. номер 47362-1G 47362-5G ПараметрыQuality Level 100, reaction suitability reaction type: Fmoc solid-phase peptide synthesis extent of labeling 0.4-0.8 mmol/g loading application(s) peptide synthesis: suitable matrix polystyrene, crosslinked with 1% DVB particle size 100-200 mesh functional group Fmoc storage temp. 2-8°C
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Arg(Pmc)-OH
Empirical Formula (Hill Notation): C35H42N4O7S CAS Number: 119831-72-0 Molecular Weight: 662.80
Кат. номер 8520349999 8520340100 8520340500 8520341000 8520340025 8520340005 8.52034.0100 8.52034.0005 8.52034.0025 General descriptionAn excellent derivative for the introduction of Arg in Fmoc SPPS. The Pmc group is removed by TFA in 1-3 hours [1-3].
For discussions on the side-reactions associated with the use of sulfonyl-based arginine protection, see [4-11].
In the synthesis of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH (852050) [5, 6, 11].
The product number for this product was previously 04-12-1073.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1073Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(011C)): 98 %
Purity (TLC(157B)): 98 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (12,5 mmol in 25 ml DMF): clearly soluble
Assay (acidimetric): 85.0 %
Water (K. F.): 1.50 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 85.0% (acidimetric), 98% (TLC), 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 70-120 °C (decomposition) functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asn(AcAcNH--Glc)-OH
Empirical Formula (Hill Notation): C33H37N3O13 CAS Number: 131287-39-3 Molecular Weight: 683.66 MDL number: MFCD00237079
Кат. номер 8521358500 8521358100 8521350001 8.52135.8500 8.52135.8100 8.52135.0001 General descriptionAn excellent derivative for the introduction of an Asn(AcNH--Glc) residue by Fmoc SPPS [1-3].
The product number for this product was previously 04-12-8100.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-8100Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): 95 %
Assay (HPLC, area%): 95.0 % (a/a)
Identity (NMR, 1H): passes test
Identity (NMR): passes test
NMR-spectrum: passes test
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95% (TLC), 95.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asn(Dmcp)-OH
Empirical Formula (Hill Notation): C25H28N2O5 CAS Number: 172947-19-2 Molecular Weight: 436.50
Кат. номер 8521190005 8521190001 8.52119.0001 8.52119.0005 General descriptionA superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Dmcp)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility.
The product number for this product was previously 04-12-1291.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1291Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): 98.0 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 95.0 %
Water (K. F.): 2.00 %
Enantiomeric purity: 99.5 % (a/a)
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95.0% (acidimetric), 98.0% (HPLC), 98.0% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asn(Dod)-OH
Empirical Formula (Hill Notation): C34H32N2O7 CAS Number: 113534-16-0 Molecular Weight: 580.63 Beilstein/REAXYS Number: 5204238 MDL number: MFCD00065623 PubChem Substance ID: 57650986
Кат. номер 47521-1G 47521-5G Параметрыassay ≥96.0% (HPLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string COc1ccc(cc1)C(NC(=O)C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)c5ccc(OC)cc5 InChI 1S/C34H32N2O7/c1-41-23-15-11-21(12-16-23)32(22-13-17-24(42-2)18-14-22)36-31(37)19-30(33(38)39)35-34(40)43-20-29-27-9-5-3-7-25(27)26-8-4-6-10-28(26)29/h3-18,29-30,32H,19-20H2,1-2H3,(H,35,40)(H,36,37)(H,38,39)/t30-/m0/s1 InChI key NUINEVHFMAGARJ-PMERELPUSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany 3 Узнать цену -
Fmoc-Asn(Mmt)-OH
Empirical Formula (Hill Notation): C39H34N2O6 Molecular Weight: 626.70
Кат. номер 8524110025 8524110100 8524110001 8524119999 8524110005 8.52411.0005 8.52411.0025 8.52411.0001 General descriptionA superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Mmt)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Mmt group is rapid, even when the residue is located at the N-terminus of a peptide.Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asn(Trt)-OH
Empirical Formula (Hill Notation): C38H32N2O5 CAS Number: 132388-59-1 Molecular Weight: 596.67 Beilstein/REAXYS Number: 4343823 MDL number: MFCD00077049 eCl@ss: 32160406 PubChem Substance ID: 57651076 NACRES: NA.26
Кат. номер 47672-100G-F 47672-25G-F 47672-5G-F 47672-1KG-F 47672-1L-F 47672-250ML-F 47672-1G-F ПараметрыQuality Level 100, assay ≥97.0% optical activity [α]20/D −15.0±1°, c = 1% in methanol reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 201-204 °C (lit.) functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@H](CC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46 InChI 1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1 InChI key KJYAFJQCGPUXJY-UMSFTDKQSA-N
Safety Informationpictograms GHS09 hcodes H411 Personal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR UN 3077 9 / PGIII WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Asn(Trt)-OPfp
Empirical Formula (Hill Notation): C44H31F5N2O5 CAS Number: 132388-64-8 Molecular Weight: 762.72
Кат. номер 8521320100 8521320025 8521320005 8.52132.0005 General descriptionThe product number for this product was previously 04-12-1538.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1538Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation 25/D (c=1 in dioxan): -9.0 - -5.0 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): 97.0% (a/a)
Solubility (0.5 mmole in 3 ml DMF): clearly soluble
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 97.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asn-OH
Empirical Formula (Hill Notation): C19H18N2O5 CAS Number: 71989-16-7 Molecular Weight: 354.36 MDL number: MFCD00037132 EC Index Number: 276-252-2
Кат. номер 8522030005 8522030100 8522039999 8522030025 8.52203.0100 8.52203.0005 8.52203.0025 General descriptionThe product number for this product was previously 04-12-1004.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1004Analysis NoteColour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(0110)): 98 %
Purity (TLC(CMA1)): 98 %
Assay (HPLC, area%): 97.0 % (a/a)
Solubility1mmol in 5ml DMF + 2 q. DIPEA: clear soluble
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 97.0% (HPLC), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 175-190 °C functional group Fmoc storage temp. 2-30°C InChI 1S/C19H18N2O5/c20-17(22)9-16(18(23)24)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,22)(H,21,25)(H,23,24) InChI key YUGBZNJSGOBFOV-UHFFFAOYSA-N Узнать цену -
Fmoc-Asp(biotinyl-PEG)-OH
Empirical Formula (Hill Notation): C39H53N5O10S Molecular Weight: 783.93
Кат. номер 8521138500 8521130001 8.52113.0001 8.52113.8500 General descriptionIn contrast to Fmoc-Lys(biotin)-OH, this novel biotin-labeled amino acid has excellent solubility in DMF and other solvents used in SPPS [1]. The PEG-spacer restricts hindrance between the peptide and avidin, leading to better biotin binding. Furthermore, the hydrophilic nature of the PEG minimizes non-specific interactions that can arise from the spacer group becoming buried in the hydrophobic pocket of proteins.
The product number for this product was previously 04-12-1279.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1279Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(CMA2)): 98 %
Assay (HPLC, area%): 95.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at +2°C to +8°C. Quality Level 200, product line Novabiochem® assay 95.0% (HPLC), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C Узнать цену -
Fmoc-Asp(EDANS)-OH
Empirical Formula (Hill Notation): C31H29N3O8S CAS Number: 182253-73-2 Molecular Weight: 603.64
Кат. номер 8521188500 8521180001 8.52118.8500 8.52118.0001 General descriptionFluorescence-labeled amino acid for preparing fluorescence-quenched peptide substrates [1]. Most frequently used in conjunction with Dabcyl quenching group.
The product number for this product was previously 04-12-1288.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1288Analysis NoteColor (visual): grey
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(CMA1)): 98 %
Assay (HPLC, area%): 95.0 % (a/a)
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95.0% (HPLC), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(O-2-PhiPr)-OH
Empirical Formula (Hill Notation): C28H27NO6 CAS Number: 200336-86-3 Molecular Weight: 473.52
Кат. номер 8520860005 8520860001 8520869999 8.52086.0005 8.52086.0001 General descriptionQuasi-orthogonally-protected Asp derivative.
The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS [2] or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(Mtt) and Asp(O-2-PhiPr) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.
This derivative has also been used in solution to prepare bicyclic helix initiating peptides [3].
The product number for this product was previously 04-12-1200
.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1200Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0 % (a/a)
Purity (TLC(011A)): 97 %
Purity (TLC(0811)): 97 %
Assay (HPLC, area%): 95.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 93.0 %
Water (K. F.): 2.0 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 93.0% (acidimetric), 95.0% (HPLC), 97% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(OAll)-OH
Empirical Formula (Hill Notation): C22H21NO6 CAS Number: 146982-24-3 Molecular Weight: 395.41 Beilstein/REAXYS Number: 6670219 MDL number: MFCD00190874 PubChem Substance ID: 57651019 NACRES: NA.26
Кат. номер 47579-1G-F 47579-5G-F ПараметрыQuality Level 100, assay ≥98.0% (HPLC) optical activity [α]20/D −27±2°, c = 1% in DMF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 111-115 °C functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@H](CC(=O)OCC=C)NC(=O)OCC1c2ccccc2-c3ccccc13 InChI 1S/C22H21NO6/c1-2-11-28-20(24)12-19(21(25)26)23-22(27)29-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,25,26)/t19-/m0/s1 InChI key FBNFRRNBFASDKS-IBGZPJMESA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Asp(OBzl)-OH
Empirical Formula (Hill Notation): C26H23NO6 CAS Number: 86060-84-6 Molecular Weight: 445.46 MDL number: MFCD00065630
Кат. номер 8520040005 8520040025 8.52004.0005 8.52004.0025 General descriptionThe product number for this product was previously 04-12-1012.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1012Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(011B)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 97.0 %
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 97.0% (acidimetric), 98% (TLC), 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 120-130 °C functional group Fmoc storage temp. 2-30°C Узнать цену -
Fmoc-Asp(ODmab)-OH
Empirical Formula (Hill Notation): C39H42N2O8 CAS Number: 269066-08-2 Molecular Weight: 666.76
Кат. номер 8520780001 8520780005 8520789999 8520780025 8.52078.0001 8.52078.0025 8.52078.0005 General descriptionQuasi-orthogonally-protected Asp derivative.
For application information, please refer to entry for 852079.
The product number for this product was previously 04-12-1175.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1175Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(157B)): 98 %
Purity (TLC(CMA2)): 98 %
Assay (HPLC, area%): 96.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Water (K. F.): 1.0 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 96.0% (HPLC), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(OEpe)-OH
Empirical Formula (Hill Notation): C26H31NO6 Molecular Weight: 453.53
Кат. номер 8524010001 8524010025 8524019999 8524010005 S8.52401.0001 8.52401.0001 8.52401.0005 General descriptionAn excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group. The combination of Asp(OEpe) and the use of 1 M Oxyma Pure in DMF for Fmoc removal results in minimal aspartimde formation.Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(OMpe)-OH
Empirical Formula (Hill Notation): C25H29NO6 CAS Number: 180675-08-5 Molecular Weight: 439.50
Кат. номер 8521040001 8521049999 8521040025 8521040005 8.52104.0001 8.52104.0005 General descriptionAn excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides [1]. The bulky OMpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu group [1, 2].
The product number for this product was previously 04-12-1259.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1259Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(OtBu)-OH
Empirical Formula (Hill Notation): C23H25NO6 CAS Number: 71989-14-5 Molecular Weight: 411.45 Beilstein/REAXYS Number: 3635671 EC Number: 276-251-7 MDL number: MFCD00037131 eCl@ss: 32160406 PubChem Substance ID: 57651040 NACRES: NA.26
Кат. номер 47618-1G-F 47618-100G-F 47618-1KG-F 47618-10G-F 47618-25G-F 47618-250MG-F ПараметрыQuality Level 100, assay ≥98.0% (HPLC) optical activity [α]20/D −24±2°, c = 1% in DMF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 148-150 °C (dec.) functional group Fmoc storage temp. 2-8°C SMILES string CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O InChI 1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1 InChI key FODJWPHPWBKDON-IBGZPJMESA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Asp(OtBu)-OPfp
Empirical Formula (Hill Notation): C29H24F5NO6 CAS Number: 86061-01-0 Molecular Weight: 577.50 MDL number: MFCD00037633
Кат. номер 8521259999 8521250005 8521250100 8.52125.0005 General descriptionThe product number for this product was previously 04-12-1502.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1502Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation 25/D (c=1 in chloroform): -3.0 - -1.0 °
DCU (DC (0004)): 2 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 90-100 °C functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp(OtBu)-OSu
Empirical Formula (Hill Notation): C27H28N2O8 CAS Number: 78553-23-8 Molecular Weight: 508.52 MDL number: MFCD00057809 PubChem Substance ID: 57650957 NACRES: NA.26
Кат. номер 47444-1G-F 47444-5G-F ПараметрыQuality Level 100, assay ≥98.0% (calc. based on dry substance, CN) optical activity [α]20/D −31±1°, c = 1% in DMF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 128-132 °C functional group Fmoc storage temp. −20°C SMILES string CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)ON4C(=O)CCC4=O InChI 1S/C27H28N2O8/c1-27(2,3)36-24(32)14-21(25(33)37-29-22(30)12-13-23(29)31)28-26(34)35-15-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,20-21H,12-15H2,1-3H3,(H,28,34)/t21-/m0/s1 InChI key OCCFRTKCROFJLW-NRFANRHFSA-N
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Fmoc-Asp-OAll
Empirical Formula (Hill Notation): C22H21NO6 CAS Number: 144120-53-6 Molecular Weight: 395.41 Beilstein/REAXYS Number: 5460108 MDL number: MFCD00467715 PubChem Substance ID: 57651018 NACRES: NA.26
Кат. номер 47578-5G-F 47578-1G-F ПараметрыQuality Level 100, assay ≥97.0% (HPLC) optical activity [α]20/D −24.5±2°, c = 1% in DMF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)OCC=C InChI 1S/C22H21NO6/c1-2-11-28-21(26)19(12-20(24)25)23-22(27)29-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,24,25)/t19-/m0/s1 InChI key ZJMVIWUCCRKNHY-IBGZPJMESA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Asp-ODmab
Empirical Formula (Hill Notation): C39H42N2O8 CAS Number: 172611-77-7 Molecular Weight: 666.76
Кат. номер 8520790005 8520799999 8520790001 8.52079.0001 8.52079.0005 General descriptionQuasi-orthogonally-protected Asp derivative.
The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis.
Occasionally sluggish cleavage of the aminobenzyl moiety is observed [2, 3]. In these instances, washing the support with 20% DIPEA in DMF/water (9:1) [2] or HCl in dioxane [4] has been found to be efficacious.
For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Asp(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.
To avoid aspartimide formation, it is advisable to employ an Hmb- or Dmb-protected derivative for introduction of the preceding residue.
For applications of this derivative in the synthesis of cyclic peptides, see references [5 - 7].
The product number for this product was previously 04-12-1176.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1176Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0 % (a/a)
Purity (TLC(157A)): 97 %
Purity (TLC(CMA2)): 97 %
Assay (HPLC, area%): 95.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Water (K. F.): 1.0 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95.0% (HPLC), 97% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Asp-OtBu
Empirical Formula (Hill Notation): C23H25NO6 CAS Number: 129460-09-9 Molecular Weight: 411.45
Кат. номер 8520370400 8520379999 8520370001 8520370005 8.52037.0001 8.52037.0005 General descriptionSelectively protected building block for library synthesis or the preparation of -aspartyl peptides. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the -amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters and amides, and lactams and lactones containing the aspartyl unit.
The product number for this product was previously 04-12-1080.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1080Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0 % (a/a)
Purity (TLC(011A)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 90.0 %
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 90.0% (acidimetric), 98% (TLC), 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 90-98 °C functional group Fmoc storage temp. 2-30°C Узнать цену -
Fmoc-azidolysine
Empirical Formula (Hill Notation): C21H22N4O4 CAS Number: 159610-89-6 Molecular Weight: 394.42
Кат. номер 8523269999 8523260005 8523260025 8523260001 8.52326.0001 General descriptionA useful tool for the synthesis of branched, side-chain modified and cyclic peptides by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols [1] or phosphines [2, 3].Analysis NoteColour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly solubleLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-bishomopropargylglycine
Empirical Formula (Hill Notation): C22H21NO4 Molecular Weight: 363.41
Кат. номер 8523248100 8523248500 8.52324.8100 8.52324.8500 General descriptionBuilding block for the introduction by Fmoc SPPS of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc) 2/pyridine and heating to 60 °C using microwaves.. Any other use of the reagent may be covered by third party patents and it is the customers obligation to check this if they have the intention to use them for other purposes beside the recommended use.Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Cit-OH
Empirical Formula (Hill Notation): C21H23N3O5 CAS Number: 133174-15-9 Molecular Weight: 397.42 Beilstein/REAXYS Number: 7780987 MDL number: MFCD00151943 PubChem Substance ID: 57650985 NACRES: NA.26
Кат. номер 47518-5G-F 47518-25G-F 47518-1G-F ПараметрыQuality Level 100, assay ≥97.0% (HPLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string NC(=O)NCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O InChI 1S/C21H23N3O5/c22-20(27)23-11-5-10-18(19(25)26)24-21(28)29-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,24,28)(H,25,26)(H3,22,23,27)/t18-/m0/s1 InChI key NBMSMZSRTIOFOK-SFHVURJKSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(4-methoxytrityl)-OH 727997-5G
Empirical Formula (Hill Notation): C38H33NO5S CAS Number: 177582-21-7 Molecular Weight: 615.74 Beilstein/REAXYS Number: 8524562 MDL number: MFCD00270541 PubChem Substance ID: 329764368 NACRES: NA.26 ПараметрыQuality Level 100, assay ≥98% (HPLC) optical activity [α]/D +14.0±1.0°, c = 1 in THF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string COc1ccc(cc1)C(SC[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)(c5ccccc5)c6ccccc6 InChI 1S/C38H33NO5S/c1-43-29-22-20-28(21-23-29)38(26-12-4-2-5-13-26,27-14-6-3-7-15-27)45-25-35(36(40)41)39-37(42)44-24-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35H,24-25H2,1H3,(H,39,42)(H,40,41)/t35-/m0/s1 InChI key LOBUWFUSGOYXQX-DHUJRADRSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(Acm)-OH
Empirical Formula (Hill Notation): C21H22N2O5S CAS Number: 86060-81-3 Molecular Weight: 414.47 Beilstein/REAXYS Number: 4725388 MDL number: MFCD00038769 PubChem Substance ID: 57651035 NACRES: NA.26
Кат. номер 47603-5G 47603-1G ПараметрыQuality Level 100, assay ≥95.0% (sum of enantiomers, HPLC) optical activity [α]/D -33.0±2.0°, c = 1 in methanol reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string CC(=O)NCSC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O InChI 1S/C21H22N2O5S/c1-13(24)22-12-29-11-19(20(25)26)23-21(27)28-10-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,18-19H,10-12H2,1H3,(H,22,24)(H,23,27)(H,25,26)/t19-/m0/s1 InChI key CSMYOORPUGPKAP-IBGZPJMESA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 - H335 pcodes P302 + P352 - P305 + P351 + P338 Target Organs Respiratory system Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(Bzl)-OPfp
Empirical Formula (Hill Notation): C31H22F5NO4S CAS Number: 86060-95-9 Molecular Weight: 599.57 Beilstein/REAXYS Number: 4649226 MDL number: MFCD00237045 PubChem Substance ID: 57650958
Кат. номер 47445-5G-F 47445-1G-F Параметрыgrade purum assay ≥98.0% (HPLC) application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string Fc1c(F)c(F)c(OC(=O)[C@H](CSCc2ccccc2)NC(=O)OCC3c4ccccc4-c5ccccc35)c(F)c1F InChI 1S/C31H22F5NO4S/c32-24-25(33)27(35)29(28(36)26(24)34)41-30(38)23(16-42-15-17-8-2-1-3-9-17)37-31(39)40-14-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,37,39)/t23-/m0/s1 InChI key PSDSBWKIZVGTFE-QHCPKHFHSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany 3 Узнать цену -
Fmoc-Cys(Dpm)-OH
Empirical Formula (Hill Notation): C31H27NO4S CAS Number: 247595-29-5 Molecular Weight: 509.62
Кат. номер 8524170005 8524170100 8524179999 8524170025 8524170250 8.52417.0025 8.52417.0005 General descriptionThe Dpm group has increased stability compared to Trt, enabling selective removal of Mtt groups on the solid phase with dilute TFA without loss of Dpm groups. Furthermore, the Dpm group is removed by treatment with 95% TFA cleavage cocktails. Racemization during carboxyl activation is lower with this derivative than with Fmoc-Cys(Trt)-OH.Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Cys(Mmt)-OH
Empirical Formula (Hill Notation): C38H33NO5S CAS Number: 177582-21-7 Molecular Weight: 615.74 MDL number: MFCD00270541
Кат. номер 8520310001 8520310005 8520319999 8520310025 8520310100 8.52031.0005 8.52031.0001 8.52031.0025 General descriptionThe Mmt group can be selectively deprotected on the solid phase with 1% TFA in DCM containing 5% TIS [1 - 4]. Reference 4 describes a novel method for on-resin disulfide bond formation which uses Cys(Mmt) in combination with Cys(tBuS).
The product number for this product was previously 04-12-1061.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1061Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0 % (a/a)
Purity (TLC(011A)): 99 %
Purity (TLC(0811)): 99 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 85.0 %
Water (K. F.): 1.0 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 85.0% (acidimetric), 98.0% (HPLC), 99% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Cys(StBu)-OH
Empirical Formula (Hill Notation): C22H25NO4S2 CAS Number: 73724-43-3 Molecular Weight: 431.57 Beilstein/REAXYS Number: 5157922 EC Number: 277-574-6 MDL number: MFCD00042617 PubChem Substance ID: 57651049 NACRES: NA.26
Кат. номер 47631-INTR 47631-1G 47631-50G 47631-10G 47631-250MG ПараметрыQuality Level 100, assay ≥95.0% (HPLC) optical activity [α]20/D −83±2°, c = 1% in ethyl acetate reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 73-77 °C functional group Fmoc storage temp. 2-8°C SMILES string CC(C)(C)SSC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O InChI 1S/C22H25NO4S2/c1-22(2,3)29-28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1 InChI key ZDUMTHLUTJOUML-IBGZPJMESA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(STmp)-OH
Empirical Formula (Hill Notation): C27H27NO7S2 CAS Number: 1403834-74-1 Molecular Weight: 541.64
Кат. номер 8523739999 8523730005 8523730001 8.52373.0005 8.52373.0001 General descriptionFmoc-Cys(STmp)-OH [1] is a novel new tool for the regioselective synthesis of multiple disulfide bridged peptides. The STmp group is stable to piperidine but is extremely easy to remove by mild thiolysis. Albericio [2] has reported removing four STmp groups on the solid phase with only three 5 minute treatments of 0.1 M N-methylmorpholine (NMM) in DMF containing 5% DTT.Legal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Cys(tBu)-OH
Empirical Formula (Hill Notation): C22H25NO4S CAS Number: 67436-13-9 Molecular Weight: 399.50 Beilstein/REAXYS Number: 4577031 MDL number: MFCD00037130 eCl@ss: 32160406 PubChem Substance ID: 57650983 NACRES: NA.26
Кат. номер 47516-5G-F 47516-25G-F 47516-1G-F ПараметрыQuality Level 100, assay ≥98.0% (HPLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string CC(C)(C)SC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O InChI 1S/C22H25NO4S/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1 InChI key IXAYZHCPEYTWHW-IBGZPJMESA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(tButhio)-OH
Empirical Formula (Hill Notation): C22H25NO4S2 CAS Number: 73724-43-3 Molecular Weight: 431.57 MDL number: MFCD00042617 EC Index Number: 277-574-6
Кат. номер 8520229999 8520220025 8520220100 8.52022.0025 General descriptionThe t-Buthio group can be selectively removed using thiols [1] or tributylphosphine[2, 3]. This protecting group is stable to TFA if thiol scavengers are not used.
The product number for this product was previously 04-12-1041.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1041Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011B)): 98 %
Purity (TLC(0811)): 98 %
Enantiomeric purity: 99.5 % (a/a)
Assay (HPLC, area%): 97.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 95.0 %
Water (K. F.): 2.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95.0% (acidimetric), 97.0% (HPLC), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 69-79 °C functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-Cys(Trt) Wang resin 18606-1G-F
MDL number: MFCD00801374 PubChem Substance ID: 329751723 NACRES: NA.26 ПараметрыQuality Level 100, reaction suitability reaction type: Fmoc solid-phase peptide synthesis extent of labeling ~0.7 mmol/g loading application(s) peptide synthesis: suitable particle size 37-75 μm functional group Fmoc storage temp. 2-8°C
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(Trt)-OH
Empirical Formula (Hill Notation): C37H31NO4S CAS Number: 103213-32-7 Molecular Weight: 585.71 Beilstein/REAXYS Number: 4221286 MDL number: MFCD00038538 eCl@ss: 32160406 PubChem Substance ID: 57651084 NACRES: NA.26
Кат. номер 47695-5G 47695-100G 47695-1KG 47695-25G 47695-1G ApplicationFmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:- Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
- Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
- Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.
Packaging5 g in glass bottleПараметрыQuality Level 100, assay ≥95.0% (sum of enantiomers, HPLC) optical activity [α]20/D +16.0±2°, c = 1% in THF reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable mp 170-173 °C (lit.) functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46 InChI 1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1 InChI key KLBPUVPNPAJWHZ-UMSFTDKQSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-Cys(Trt)-OPfp
Empirical Formula (Hill Notation): C43H30F5NO4S CAS Number: 115520-21-3 Molecular Weight: 751.76 MDL number: MFCD00065639
Кат. номер 8521260100 8521260005 8521260025 8521260050 8.52126.0005 General descriptionAn excellent derivative for the introduction of Cys(Trt) without enantiomerization [1,2].
The product number for this product was previously 04-12-1504.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-12-1504Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation 25/D (c=1 in chloroform): +14.0 - +17.0 °
Purity (TLC (0004)): <3% DCU
Assay (HPLC, area%): 97.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 97.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-D-1-Nal-OH
Empirical Formula (Hill Notation): C28H23NO4 CAS Number: 138774-93-3 Molecular Weight: 437.49 Beilstein/REAXYS Number: 9160026 MDL number: MFCD00191200 PubChem Substance ID: 57650950 NACRES: NA.26
Кат. номер 47432-1G-F 47432-5G-F ПараметрыQuality Level 100, assay 96.0% (HPLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)OCC3c4ccccc4-c5ccccc35 InChI 1S/C28H23NO4/c30-27(31)26(16-19-10-7-9-18-8-1-2-11-20(18)19)29-28(32)33-17-25-23-14-5-3-12-21(23)22-13-4-6-15-24(22)25/h1-15,25-26H,16-17H2,(H,29,32)(H,30,31)/t26-/m1/s1 InChI key ORWNVJDLEMVDLV-AREMUKBSSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-D-2-Nal-OH
Empirical Formula (Hill Notation): C28H23NO4 CAS Number: 138774-94-4 Molecular Weight: 437.49 Beilstein/REAXYS Number: 7864489 MDL number: MFCD00077044 PubChem Substance ID: 57650968 NACRES: NA.26
Кат. номер 47471-5G 47471-1G ПараметрыQuality Level 100, assay 98.0% (HPLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)OCC3c4ccccc4-c5ccccc35 InChI 1S/C28H23NO4/c30-27(31)26(16-18-13-14-19-7-1-2-8-20(19)15-18)29-28(32)33-17-25-23-11-5-3-9-21(23)22-10-4-6-12-24(22)25/h1-15,25-26H,16-17H2,(H,29,32)(H,30,31)/t26-/m1/s1 InChI key JYUTZJVERLGMQZ-AREMUKBSSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-D-Ala-OH
Empirical Formula (Hill Notation): C18H17NO4 CAS Number: 79990-15-1 Molecular Weight: 311.33 MDL number: MFCD00062960
Кат. номер 8521429999 8521420100 8521421000 8521420005 8521420025 8.52142.0100 8.52142.0025 8.52142.0005 General descriptionThe product number for this product was previously 04-13-1006.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-13-1006Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(011A)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 99.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 93.0 %
Water (K. F.): 6.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 93.0% (acidimetric), 98% (TLC), 99.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 113-123 °C functional group Fmoc storage temp. 2-30°C Узнать цену -
Fmoc-D-Ala-OPfp
Empirical Formula (Hill Notation): C24H16F5NO4 CAS Number: 125043-04-1 Molecular Weight: 477.38 MDL number: MFCD00153372 PubChem Substance ID: 57652824 NACRES: NA.26
Кат. номер 80061-5G 80061-1G ПараметрыQuality Level 100, assay 98.0% reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string C[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)Oc4c(F)c(F)c(F)c(F)c4F InChI 1S/C24H16F5NO4/c1-11(23(31)34-22-20(28)18(26)17(25)19(27)21(22)29)30-24(32)33-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,30,32)/t11-/m1/s1 InChI key CJXZXBGKOSXBFR-LLVKDONJSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-D-Arg(Pbf)-OH
Empirical Formula (Hill Notation): C34H40N4O7S CAS Number: 187618-60-6 Molecular Weight: 648.77 Beilstein/REAXYS Number: 9537282 MDL number: MFCD00237010 eCl@ss: 32160406 PubChem Substance ID: 57650928 NACRES: NA.26
Кат. номер 47348-1G 47348-5G ПараметрыQuality Level 100, assay 98.0% (TLC) reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string Cc1c(C)c(c(C)c2CC(C)(C)Oc12)S(=O)(=O)NC(=N)NCCC[C@@H](NC(=O)OCC3c4ccccc4-c5ccccc35)C(O)=O InChI 1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m1/s1 InChI key HNICLNKVURBTKV-MUUNZHRXSA-N
Safety InformationPersonal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Fmoc-D-Asn(Trt)-OH
Empirical Formula (Hill Notation): C38H32N2O5 CAS Number: 180570-71-2 Molecular Weight: 596.67 MDL number: MFCD00151919
Кат. номер 8521590005 8521591000 8521590025 8521590100 8.52159.0025 8.52159.0005 General descriptionThe product number for this product was previously 04-13-1055.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-13-1055Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(011A)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 99.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 95.0 %
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at -15°C to -25°C. Quality Level 200, product line Novabiochem® assay 95.0% (acidimetric), 98% (TLC), 99.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable mp 210-220 °C functional group Fmoc storage temp. 15-25°C Узнать цену -
Fmoc-D-Asn-OH
Empirical Formula (Hill Notation): C19H18N2O5 CAS Number: 108321-39-7 Molecular Weight: 354.36 MDL number: MFCD00062956
Кат. номер 8522360005 8522360025 8.52236.0005 8.52236.0025 General descriptionThe product number for this product was previously 04-13-1042.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-13-1042Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(CMA1)): 98 %
Purity (TLC(0110)): 98 %
Assay (HPLC, area%): 97.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 97.0 %
Water (K. F.): 1.0 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 97.0% (HPLC), 97.0% (acidimetric), 98% (TLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-30°C Узнать цену -
Fmoc-D-Asp(OtBu)-OH
Empirical Formula (Hill Notation): C23H25NO6 CAS Number: 112883-39-3 Molecular Weight: 411.45 MDL number: MFCD00077050
Кат. номер 8521540005 8521541000 8521540025 8521540100 8.52154.0025 8.52154.0005 General descriptionThe product number for this product was previously 04-13-1050.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-13-1050Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.5 % (a/a)
Purity (TLC(011A)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 99.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 96.0 %
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 96.0% (acidimetric), 98% (TLC), 99.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-30°C Узнать цену -
Fmoc-D-Asp-OtBu
Empirical Formula (Hill Notation): C23H25NO6 CAS Number: 134098-70-7 Molecular Weight: 411.45
Кат. номер 8521440005 8521441000 8521440001 8.52144.0005 8.52144.0001 General descriptionThe product number for this product was previously 04-13-1011.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.LinkageReplaces: 04-13-1011Analysis NoteColor (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: 99.0 % (a/a)
Purity (TLC(011A)): 98 %
Purity (TLC(0811)): 98 %
Assay (HPLC, area%): 98.0 % (a/a)
Solubility (1mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): 95.0 %
Water (K. F.): 1.00 %
For TLC-Systems see our General CatalogLegal InformationNovabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +30°C. Quality Level 200, product line Novabiochem® assay 95.0% (acidimetric), 98% (TLC), 98.0% (HPLC) form powder reaction suitability reaction type: Fmoc solid-phase peptide synthesis Торговая марка Novabiochem® application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-30°C Узнать цену
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