Dexamethasone Acetate
Empirical Formula (Hill Notation): | C24H31FO6 |
CAS Number: | 1177-87-3 |
Molecular Weight: | 434.50 |
Beilstein/REAXYS Number: | 2342608 |
EC Number: | 214-646-8 |
MDL number: | MFCD00027407 |
PubChem Substance ID: | 329823439 |
NACRES: | NA.24 |
Кат. номер |
PHR1527-1G |
PHR1527-1G-PW |
Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Dexamethasone Acetate is a steroid used for the treatment of various diseases because of its anti-inflammatory and inmunosuppresor effects. It is a common component of ointments, creams, lotions, aerosols and microemulsions.
Dexamethasone Acetate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
Dexamethasone acetate is used as a pharmaceutical reference standard for the quantification the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3645 in the slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
biological source | synthetic |
grade | certified reference material, pharmaceutical secondary standard |
Agency/Method | BP, EP, USP |
vapor pressure | <0.0000001 kPa ( 25 °C) |
CofA | current certificate can be downloaded |
packaging | pkg of 1 g |
storage condition | protect from light (20 mm aluminium crimp seal for unused portion) |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
color | white |
mp | 460.4-464 °F (238—240°C) |
solubility | acetone: freely soluble, dichloromethane: slightly soluble, methanol: freely soluble, water: practically insoluble |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to PhEur D0710000, traceable to USP 1176506 |
shipped in | ambient |
SMILES string | [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O |
InChI | 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1 |
InChI key | AKUJBENLRBOFTD-RPRRAYFGSA-N |
Gene Information | human ... NR3C1(2908) |
pictograms | GHS07 |
signalword | Warning |
hcodes | H317 |
pcodes | P280 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |