Ampicillin Sodium
Empirical Formula (Hill Notation): | C16H18N3NaO4S |
CAS Number: | 69-52-3 |
Molecular Weight: | 371.39 |
Beilstein/REAXYS Number: | 4119211 |
EC Number: | 200-708-1 |
MDL number: | MFCD00064313 |
PubChem Substance ID: | 329822591 |
NACRES: | NA.24 |
Кат. номер |
PHR1424-1G |
PHR1424-1G-PW |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ampicillin Sodium may be used as a pharmaceutical secondary reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography with ultra violet detection and second-derivative spectrophotometry, respectively.
Mode of Action: This is a -lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
Mode of Resistance: Administration with -lactamase cleaves the -lactam ring of Ampicillin and inactivates it.
Antimicrobial Spectrum: Includes both gram-positive (similar to benzylpenicillin) and gram-negative bacteria (similar to tetracyclines and chloramphenicol.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2732 in the slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
grade | certified reference material, pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
mp | 215 °C (dec.) (lit.) |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to BP 785, traceable to PhEur A1000000, traceable to USP 1033203 |
SMILES string | [Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O |
InChI | 1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1 |
InChI key | KLOHDWPABZXLGI-YWUHCJSESA-M |
pictograms | GHS08 |
signalword | Danger |
hcodes | H317 - H334 |
pcodes | P261 - P280 - P342 + P311 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |