trans-Anethole
Empirical Formula (Hill Notation): | C10H12O |
Linear Formula: | CH3CH=CHC6H4OCH3 |
CAS Number: | 4180-23-8 |
Molecular Weight: | 148.20 |
Beilstein/REAXYS Number: | 774229 |
EC Number: | 224-052-0 |
MDL number: | MFCD00009284 |
PubChem Substance ID: | 329823225 |
NACRES: | NA.24 |
Кат. номер |
PHR1218-2.2ML |
PHR1218-2.2ML-PW |
trans-Anethole is an aromatic monoterpenoid compound and derivative of phenylpropene. It is predominantly used as a fragrance in cosmetics and as a flavoring agent in food and pharmaceutical industries.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
trans-Anethole may be used as an analytical reference standard for the determination of the analyte in raw material, food products and pharmaceutical formulations by high performance liquid chromatography and gas chromatography.
Naturally occurring phenylpropene derivative that is estrogenic at lower concentrations and cytotoxic at higher concentrations to cancer cell lines. The cytotoxicity is related to the metabolism of
trans-anethole to 4-hydroxy-1-propenylbenzene.
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3326 in the slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
grade | certified reference material, pharmaceutical secondary standard |
form | neat |
CofA | current certificate can be downloaded |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
refractive index | n20/D 1.561 (lit.) |
bp | 234-237 °C (lit.) |
mp | 20-21 °C (lit.) |
density | 0.988 g/mL at 25 °C (lit.) |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to USP 1035005 |
SMILES string | COc1ccc(\C=C\C)cc1 |
InChI | 1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+ |
InChI key | RUVINXPYWBROJD-ONEGZZNKSA-N |
pictograms | GHS07,GHS09 |
signalword | Warning |
hcodes | H317 - H411 |
pcodes | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point F | 213.8 °F |
Flash Point C | 101 °C |