Theophylline melting point standard
Empirical Formula (Hill Notation): | C7H8N4O2 |
CAS Number: | 58-55-9 |
Molecular Weight: | 180.16 |
Beilstein/REAXYS Number: | 13463 |
EC Number: | 200-385-7 |
MDL number: | MFCD00079619 |
PubChem Substance ID: | 329823169 |
NACRES: | NA.24 |
Кат. номер |
PHR1151-1G |
PHR1151-1G-PW |
Theophylline is a naturally occurring alkaloid. In addition to its bronchodilator, immunomodulatory and anti-inflammatory effects, it also acts as a respiratory stimulant, used in the treatment of asthma.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Theophylline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques.
Phosphodiesterase inhibitor; diuretic; cardiac stimulant; muscle relaxant; asthma medication.
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7175 in the slot below. This is an example certificate only and may not be the lot that you receive.
Quality Level | 300 |
grade | certified reference material, pharmaceutical secondary standard |
form | neat |
CofA | current certificate can be downloaded |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
mp | ~Approximately 272 °C |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to USP 1653117 |
SMILES string | CN1C(=O)N(C)c2[nH]cnc2C1=O |
InChI | 1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) |
InChI key | ZFXYFBGIUFBOJW-UHFFFAOYSA-N |
Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE3A(5139), PDE3B(5140), PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144) |
pictograms | GHS06 |
signalword | Danger |
hcodes | H301 |
pcodes | P301 + P330 + P331 + P310 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 1 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |