Cell Culture Supplements & Reagents
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L-Histidine methyl ester dihydrochloride
Empirical Formula (Hill Notation): C7H11N3O2 · 2HCl CAS Number: 7389-87-9 Molecular Weight: 242.10 Beilstein/REAXYS Number: 3572009 EC Number: 230-973-9 MDL number: MFCD00012701 eCl@ss: 32160406 PubChem Substance ID: 24895465 NACRES: NA.22
Кат. номер H15403-25G H15403-100G H15403-5G ПараметрыQuality Level 100, assay 97% optical activity []20/D +9.0°, c = 2 in H2O reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color white mp 207 °C (dec.) (lit.) SMILES string Cl.Cl.COC(=O)[C@@H](N)Cc1c[nH]cn1 InChI 1S/C7H11N3O2.2ClH/c1-12-7(11)6(8)2-5-3-9-4-10-5;;/h3-4,6H,2,8H2,1H3,(H,9,10);2*1H/t6-;;/m0../s1 InChI key DWAYENIPKPKKMV-ILKKLZGPSA-N
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L-Histidine monohydrochloride monohydrate
Empirical Formula (Hill Notation): C6H9N3O2 · HCl · H2O CAS Number: 5934-29-2 Molecular Weight: 209.63 Beilstein/REAXYS Number: 4168261 MDL number: MFCD00151027 eCl@ss: 32160406 PubChem Substance ID: 24895703 NACRES: NA.26
Кат. номер H5659-1KG H5659-100G H5659-25G H5659-25KG H5659-BR ApplicationL-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.
L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.Packaging25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.Параметрыbiological source non-animal source Quality Level 200, Agency/Method meets EP testing specifications product line BioXtra assay 98.5-101.0% form crystalline powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white mp 254 °C (dec.) (lit.) solubility H2O: 100 mg/mL SMILES string O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O InChI 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1 InChI key CMXXUDSWGMGYLZ-XRIGFGBMSA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H319 pcodes P264 - P280 - P305 + P351 + P338 - P337 + P313 Personal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Histidinol dihydrochloride
Empirical Formula (Hill Notation): C6H11N3O · 2HCl CAS Number: 1596-64-1 Molecular Weight: 214.09 Beilstein/REAXYS Number: 3914853 EC Number: 216-482-2 MDL number: MFCD00078058 PubChem Substance ID: 24895755 NACRES: NA.32
Кат. номер H6647-10MG H6647-1G H6647-5G H6647-250MG H6647-100MG H6647-500MG ApplicationL-Histidinol dihydrochloride has been used:- as a reagent in urinary metabolite analysis
- for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
- for inducing amino acid deprivation in HepG2 cells
Packaging1, 5 g in poly bottle
10 mg in glass bottleBiochem/physiol ActionsPrecursor of histamine; reversible inhibitor of protein synthesis.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H6647.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 98 (TLC) form powder application(s) cell analysis: suitable color white to off-white mp 198-201 °C (dec.) (lit.) SMILES string Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1 InChI 1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1 InChI key FRCAFNBBXRWXQA-XRIGFGBMSA-N Gene Information human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448)
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 - H335 pcodes P302 + P352 - P305 + P351 + P338 Target Organs Respiratory system Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Homoarginine hydrochloride
Empirical Formula (Hill Notation): C7H16N4O2 · HCl Linear Formula: H2NC(=NH)NH(CH2)4CH(NH2)CO2H · HCl CAS Number: 1483-01-8 Molecular Weight: 224.69 Beilstein/REAXYS Number: 4016621 EC Number: 216-045-6 MDL number: MFCD00012622 PubChem Substance ID: 24895420 NACRES: NA.26
Кат. номер H1007-5G H1007-250MG H1007-1G ApplicationL-Homoarginine may be used to create non-natural proteins for studies of post-translational protein modifications. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements. L-Homoarginine is used to study the mechanisms of nitric oxide production by cells via nitric oxide synthase(s). L-Homoarginine is used as a selective mammalian alkaline phosphatase isoenzyme inhibitor. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin.
The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.Packaging5 g in poly bottleBiochem/physiol ActionsHomoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) peptide synthesis: suitable color white to off-white mp 213-215 °C (lit.) solubility H2O: soluble SMILES string Cl[H].N[C@@H](CCCCNC(N)=N)C(O)=O InChI 1S/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/m0./s1 InChI key YMKBVNVCKUYUDM-JEDNCBNOSA-N
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L-Homocysteic acid
Empirical Formula (Hill Notation): C4H9NO5S CAS Number: 14857-77-3 Molecular Weight: 183.18 MDL number: MFCD00066018 PubChem Substance ID: 24895863 NACRES: NA.32
Кат. номер H9633-25MG H9633-1G H9633-250MG H9633-100MG ApplicationL-Homocysteic acid has been used to study hydrogen peroxide-mediated changes in physiological and pathological conditions in the nervous system.Packaging1 g in poly bottle
25, 100, 250 mg in poly bottleBiochem/physiol ActionsL-Homocysteic acid (L-HCA) is an endogenous neurotransmitter ligand of NMDA (N-methyl-D-aspartate) receptors. It is an analog of glutamate and competitively suppresses glutamate-cystine (xc-) antiporter function in neurons, causing decrease in cysteine uptake.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H9633.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,Параметрыassay 98% (TLC) Quality Level 200, form powder application(s) cell analysis: suitable color white to off-white SMILES string N[C@@H](CCS(O)(=O)=O)C(O)=O InChI 1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1 InChI key VBOQYPQEPHKASR-VKHMYHEASA-N
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L-Homocysteine thiolactone hydrochloride
Empirical Formula (Hill Notation): C4H7NOS · HCl CAS Number: 31828-68-9 Molecular Weight: 153.63 Beilstein/REAXYS Number: 3911455 EC Number: 250-824-1 MDL number: MFCD00065494 eCl@ss: 32160406 PubChem Substance ID: 24895745 NACRES: NA.26
Кат. номер H6503-5G H6503-250MG H6503-100MG H6503-1G H6503-25MG Packaging1, 5 g in glass bottle
100, 250 mg in glass bottleBiochem/physiol ActionsL-Homocysteine thiolactone, an amine reactive agent, is used to study post-translational modification of proteins, especially at lysine residues.ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) detection: suitable, peptide synthesis: suitable color white mp 185 °C SMILES string Cl[H].N[C@H]1CCSC1=O InChI 1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1 InChI key ZSEGSUBKDDEALH-DFWYDOINSA-N
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L-Homocystine
Empirical Formula (Hill Notation): C8H16N2O4S2 CAS Number: 626-72-2 Molecular Weight: 268.35 Beilstein/REAXYS Number: 1728583 EC Number: 210-962-5 MDL number: MFCD00020391 PubChem Substance ID: 24895724 NACRES: NA.26
Кат. номер H6010-100MG H6010-PM H6010-1G H6010-500MG Packaging100, 500 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsL-Homocystine is the oxidized member of the L-homocysteine:L-homocystine pair. Homocysteine/homocystine is derived from methionine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.ПараметрыQuality Level 300, assay 98% (HPLC) form powder application(s) cell analysis: suitable, peptide synthesis: suitable color white to off-white mp 281-284 °C (dec.) (lit.) SMILES string N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O InChI 1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6-/m0/s1 InChI key ZTVZLYBCZNMWCF-WDSKDSINSA-N
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L-Homoserine
Empirical Formula (Hill Notation): C4H9NO3 Linear Formula: HOCH2CH2CH(NH2)CO2H CAS Number: 672-15-1 Molecular Weight: 119.12 Beilstein/REAXYS Number: 1721681 EC Number: 211-590-6 MDL number: MFCD00063090 eCl@ss: 32160406 PubChem Substance ID: 24895748 NACRES: NA.26
Кат. номер H6515-1G H6515-10MG H6515-250MG H6515-5G General descriptionL-Homoserine is a variant of serine with an additional carbon on its side chain.ApplicationL-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.Packaging10, 250 mg in poly bottle
1, 5 g in poly bottleBiochem/physiol ActionsL-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H6515.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,Параметрыassay 98% (TLC) Quality Level 100, form powder application(s) cell analysis: suitable, detection: suitable color white to off-white mp 203 °C (dec.) (lit.) SMILES string N[C@@H](CCO)C(O)=O InChI 1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1 InChI key UKAUYVFTDYCKQA-VKHMYHEASA-N
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L-Homoserine lactone hydrochloride
Empirical Formula (Hill Notation): C4H7NO2 · HCl CAS Number: 2185-02-6 Molecular Weight: 137.56 MDL number: MFCD00058172 PubChem Substance ID: 24895811 NACRES: NA.26
Кат. номер H7890-1G H7890-250MG H7890-5G General descriptionL-Homoserine lactone (HSL), also called acyl-HSL, comprises a homoserine lactone ring and a fatty acyl side. The levels of acyl-HSL in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase.ApplicationL-Homoserine lactone hydrochloride has been used as an inhibitor for arterial smooth muscle contraction.Packaging250 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsL-Homoserine lactone inhibition reduces virulence factors and halts inflammation and tissue damage. In Pseudomonas aeruginosa it controls virulence factor production and biofilm formation. In Agrobacterium tumefaciens, it is essential for conjugal transfer.
Acylated L-Homoserine lactone(s) are used to study bacterial quorum-sensing signaling mechanisms.Параметрыform powder Quality Level 200, application(s) ligand binding assay: suitable color white storage temp. 20°C SMILES string Cl.N[C@H]1CCOC1=O InChI 1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1 InChI key XBKCXPRYTLOQKS-DFWYDOINSA-N
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L-Isoleucine
Empirical Formula (Hill Notation): C6H13NO2 Linear Formula: C2H5CH(CH3)CH(NH2)CO2H CAS Number: 73-32-5 Molecular Weight: 131.17 Beilstein/REAXYS Number: 1721792 EC Number: 200-798-2 MDL number: MFCD00064222 eCl@ss: 32160406 PubChem Substance ID: 24896006 NACRES: NA.26
Кат. номер I2752-VAR I2752-1G-KC I2752-100G I2752-10G I2752-5G I2752-25G I2752-1G I2752-1KG ApplicationL-Isoleucine has been used in capillary feeder (CAFE) assay in a study to determine the consumption of amino acids by Drosophila melanogaster. It has also been used as one of the components of an amino acid mixture, which is used as a supplement for synthetic complete (SC) media.Packaging1, 5, 10, 25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Isoleucine is an isomer of L-leucine and is an essential amino acid. It is synthesized from threonine and is a branched-chain hydrophobic amino acid.Параметрыgrade reagent grade Quality Level 200, assay 98% (HPLC) form powder application(s) detection: suitable color white mp 288 °C (dec.) (lit.) solubility 1 M NH4OH: 50 mg/mL SMILES string CC[C@H](C)[C@H](N)C(O)=O InChI 1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1 InChI key AGPKZVBTJJNPAG-WHFBIAKZSA-N
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L-Isoleucine -naphthylamide
Empirical Formula (Hill Notation): C16H20N2O CAS Number: 732-84-3 Molecular Weight: 256.34 MDL number: MFCD00055912 PubChem Substance ID: 24896063 NACRES: NA.26
Кат. номер I4879-1G I4879-250MG I4879-100MG Параметрыassay 98% (TLC) Quality Level 200, form powder color white to off-white storage temp. 2-8°C SMILES string CC[C@H](C)[C@H](N)C(=O)Nc1ccc2ccccc2c1 InChI 1S/C16H20N2O/c1-3-11(2)15(17)16(19)18-14-9-8-12-6-4-5-7-13(12)10-14/h4-11,15H,3,17H2,1-2H3,(H,18,19)/t11-,15-/m0/s1 InChI key CEZPKIGJZWWHJT-NHYWBVRUSA-N
Safety Informationpictograms GHS08 signalword Warning hcodes H351 pcodes P281 Personal Protective Equipment Eyeshields,, Gloves,, type P1 (EN143) respirator filter,, type P3 (EN 143) respirator cartridges, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Isoserine
Empirical Formula (Hill Notation): C3H7NO3 CAS Number: 632-13-3 Molecular Weight: 105.09 MDL number: MFCD03428326 PubChem Substance ID: 329748201 NACRES: NA.22
Кат. номер 6054-1G-F 6054-VAR-F ПараметрыQuality Level 100, assay 98.0% (TLC) form powder reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color white to off-white mp 197-198 °C SMILES string NC[C@H](O)C(O)=O InChI 1S/C3H7NO3/c4-1-2(5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1 InChI key BMYNFMYTOJXKLE-REOHCLBHSA-N
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L-Kynurenine
Empirical Formula (Hill Notation): C10H12N2O3 CAS Number: 2922-83-0 Molecular Weight: 208.21 MDL number: MFCD00069912 PubChem Substance ID: 24896246
Кат. номер K8625-100MG K8625-1G K8625-500MG K8625-25MG ApplicationL-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.Biochem/physiol ActionsL-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. It is involved in a variety of neurological processes and diseases. L-Kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.
Key intermediate in the breakdown pathway of tryptophan.ПараметрыQuality Level 200, assay 98% (HPLC) form powder application(s) detection: suitable color light yellow mp 219 °C SMILES string N[C@@H](CC(=O)c1ccccc1N)C(O)=O InChI 1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1 InChI key YGPSJZOEDVAXAB-QMMMGPOBSA-N
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L-Kynurenine sulfate salt
Empirical Formula (Hill Notation): C10H12N2O3 · H2O4S Linear Formula: C10H12N2O3 · H2SO4 CAS Number: 16055-80-4 Molecular Weight: 306.29 MDL number: MFCD00039104 PubChem Substance ID: 24896233 NACRES: NA.26
Кат. номер K3750-1G K3750-5G K3750-500MG K3750-100MG ApplicationL-Kynurenine sulfate salt has been used as a substrate to study the enzyme activity of kynurenine aminotransferase. It has also been used in the synthesis of Kyn adducts of certain amino acids .Biochem/physiol ActionsL-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.
L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammals, it modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.
Key intermediate in the breakdown pathway of tryptophan.Параметрыassay 98% (HPLC) Quality Level 200, form crystalline application(s) ligand binding assay: suitable color light yellow storage temp. 20°C SMILES string OS(O)(=O)=O.N[C@@H](CC(=O)c1ccccc1N)C(O)=O InChI 1S/C10H12N2O3.H2O4S/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15;1-5(2,3)4/h1-4,8H,5,11-12H2,(H,14,15);(H2,1,2,3,4)/t8-;/m0./s1 InChI key KAXRWMOLNJZCEW-QRPNPIFTSA-N
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L-Leucine
Empirical Formula (Hill Notation): C6H13NO2 Linear Formula: (CH3)2CHCH2CH(NH2)CO2H CAS Number: 61-90-5 Molecular Weight: 131.17 Beilstein/REAXYS Number: 1721722 EC Number: 200-522-0 MDL number: MFCD00002617 eCl@ss: 32160406 PubChem Substance ID: 24896510 NACRES: NA.26
Кат. номер L8912-100G L8912-10MG L8912-1KG L8912-25G L8912-BR ApplicationL-leucine has been used as a hypertrophic agent to monitor its effects on myotubes. It has also been used as a component of PMG media for culturing yeast.Packaging10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsLeucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.Параметрыbiological source non-animal source Quality Level 300, Agency/Method USP/NF, meets EP testing specifications, meets JP testing specifications, meets USP testing specifications assay 98.5-101.0% form powder quality meets EP, JP, USP testing specifications application(s) cell culture | mammalian: suitable, peptide synthesis: suitable impurities endotoxin, tested color white mp >300 °C (lit.) solubility 1 M HCl: 50 mg/mL Featured Industry Pharmaceutical (small molecule) SMILES string CC(C)C[C@H](N)C(O)=O InChI 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 InChI key ROHFNLRQFUQHCH-YFKPBYRVSA-N
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L-Leucine 3-carboxy-4-hydroxyanilide hydrochloride
Empirical Formula (Hill Notation): C13H18N2O4 · HCl CAS Number: 73801-31-7 Molecular Weight: 302.75 MDL number: MFCD00058075 PubChem Substance ID: 24896522
Кат. номер L9384-10MG L9384-25MG L9384-250MG L9384-100MG ApplicationL-Leucine 3-carboxy-4-hydroxyanilide may be used as a substrate for determining the activity of microsomal aminopeptidase in serum.Параметрыapplication(s) ligand binding assay: suitable storage temp. 2-8°C SMILES string Cl.CC(C)C[C@H](N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI 1S/C13H18N2O4.ClH/c1-7(2)5-10(14)12(17)15-8-3-4-11(16)9(6-8)13(18)19;/h3-4,6-7,10,16H,5,14H2,1-2H3,(H,15,17)(H,18,19);1H/t10-;/m0./s1 InChI key BSVJWFHAORBGDY-PPHPATTJSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany 3 Узнать цену -
L-Leucine methyl ester hydrochloride
Empirical Formula (Hill Notation): C7H15NO2 · HCl Linear Formula: (CH3)2CHCH2CH(NH2)COOCH3 · HCl CAS Number: 7517-19-3 Molecular Weight: 181.66 Beilstein/REAXYS Number: 3595133 EC Number: 231-375-0 MDL number: MFCD00012494 eCl@ss: 32160406 PubChem Substance ID: 24896269 NACRES: NA.22
Кат. номер L1002-25G L1002-10G ПараметрыQuality Level 100, assay 98% form powder or crystals optical activity []22/D +13°, c = 2 in H2O reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color white mp 151-153 °C (lit.) SMILES string Cl[H].COC(=O)[C@@H](N)CC(C)C InChI 1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1 InChI key DODCBMODXGJOKD-RGMNGODLSA-N
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L-Leucine tert-butyl ester hydrochloride
Empirical Formula (Hill Notation): C10H21NO2 · HCl Linear Formula: (CH3)2CHCH2CH(NH2)COOC(CH3)3 · HCl CAS Number: 2748-02-9 Molecular Weight: 223.74 Beilstein/REAXYS Number: 3697141 MDL number: MFCD00038906 PubChem Substance ID: 24896301 NACRES: NA.26
Кат. номер L2125-5G L2125-500MG L2125-1G Параметрыassay 98% (TLC) Quality Level 200, form powder color white storage temp. 20°C SMILES string Cl.CC(C)C[C@H](N)C(=O)OC(C)(C)C InChI 1S/C10H21NO2.ClH/c1-7(2)6-8(11)9(12)13-10(3,4)5;/h7-8H,6,11H2,1-5H3;1H/t8-;/m0./s1 InChI key RFUWRXIYTQGFGA-QRPNPIFTSA-N
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L-Lysine
Empirical Formula (Hill Notation): C6H14N2O2 Linear Formula: H2N(CH2)4CH(NH2)CO2H CAS Number: 56-87-1 Molecular Weight: 146.19 Beilstein/REAXYS Number: 1722531 EC Number: 200-294-2 MDL number: MFCD00064433 eCl@ss: 32160406 PubChem Substance ID: 24896404 NACRES: NA.26
Кат. номер L5501-10MG L5501-100G L5501-5G L5501-25G L5501-1G General descriptionL-lysine contains basic side chain and is hydrophilic in nature. The N-butyl amino group in the side chain is found to be protonated at physiological pH. Upon degradation, L-lysine gives ketone bodies. Transamination of lysine with α-ketoglutarate produces acetoacetyl CoA. L-lysine serves as a precursor for secondary metabolites, such as β-lactam antibiotics. It also serves as a precursor for the biosynthesis of α-aminoadipic acid.ApplicationL-Lysine is an essential proteinogenic amino acid used in a wide range of applications. It has been used:- as a supplement in cell culture media
- as a substrate for enzymes such as L-lysine oxidase (EC 1.4.3.14)
- as a component of poly-lysine polymers
- as a substrate for oxidation and glycation mechanism studies
- in the preparation of cobaltous lysine
Packaging10 mg in autosample vial
1, 5, 25, 100 g in poly bottleПараметрыQuality Level 200 assay 98% (TLC) form powder application(s) ligand binding assay: suitable color white to off-white mp 215 °C (dec.) (lit.) solubility H2O: soluble SMILES string NCCCC[C@H](N)C(O)=O InChI 1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1 InChI key KDXKERNSBIXSRK-YFKPBYRVSA-N
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L-Lysine acetate salt
Empirical Formula (Hill Notation): C6H14N2O2 · C2H4O2 CAS Number: 57282-49-2 Molecular Weight: 206.24 EC Number: 260-664-4 MDL number: MFCD00039069 PubChem Substance ID: 329817395 NACRES: NA.26
Кат. номер L1884-100G L1884-25G L1884-500G Packaging25, 100, 500 g in poly bottleBiochem/physiol ActionsL-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies.ПараметрыQuality Level 200, assay 98% (HPLC) form powder application(s) ligand binding assay: suitable color white SMILES string CC(O)=O.NCCCC[C@H](N)C(O)=O InChI 1S/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m0./s1 InChI key RRNJROHIFSLGRA-JEDNCBNOSA-N
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L-Lysine dihydrochloride
Empirical Formula (Hill Notation): C6H14N2O2 · 2HCl Linear Formula: NH2(CH2)4CH(NH2)COOH · 2HCl CAS Number: 657-26-1 Molecular Weight: 219.11 Beilstein/REAXYS Number: 4539715 EC Number: 211-518-3 MDL number: MFCD00066389 PubChem Substance ID: 24896413 NACRES: NA.26
Кат. номер L5751-25G L5751-100G Packaging25, 100 g in poly bottleBiochem/physiol ActionsL-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies.ПараметрыQuality Level 200, assay 98% (HPLC) form powder application(s) ligand binding assay: suitable color white to faint yellow mp 200-206 °C (lit.) SMILES string Cl[H].Cl[H].NCCCC[C@H](N)C(O)=O InChI 1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m0../s1 InChI key JBBURJFZIMRPCZ-XRIGFGBMSA-N
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L-Lysine methyl ester dihydrochloride
Empirical Formula (Hill Notation): C7H16N2O2 · 2HCl CAS Number: 26348-70-9 Molecular Weight: 233.14 EC Number: 247-625-7 MDL number: MFCD00039067 PubChem Substance ID: 24896262 NACRES: NA.26
Кат. номер L0645-5G L0645-25G L0645-100G L0645-250G ApplicationL-Lysine methyl ester is used in the production of lysine methyl ester based cationic surfactants and hydrogels.Параметрыassay 99% (TLC) Quality Level 200, form powder color white storage temp. 20°C SMILES string Cl.COC(=O)C(N)CCCCN InChI 1S/C7H16N2O2.ClH/c1-11-7(10)6(9)4-2-3-5-8;/h6H,2-5,8-9H2,1H3;1H InChI key FORVAIDSGSLRPX-UHFFFAOYSA-N
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L-Lysine monohydrate
Empirical Formula (Hill Notation): C6H14N2O2 · H2O CAS Number: 39665-12-8 Molecular Weight: 164.20 Beilstein/REAXYS Number: 4349963 EC Number: 200-294-2 MDL number: MFCD00151035 PubChem Substance ID: 24896515
Кат. номер L9037-100G L9037-1KG L9037-25G L9037-25KG General descriptionL-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.ApplicationL-Lysine monohydrate has been used in:- SILAC (stable isotope labeling by amino acids in cell culture) method
- the complete synthetic (C) medium for positive selection screening of yeast cells
- the growth medium for cells
Packaging25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies.Параметрыbiological source non-animal source Quality Level 200, product line BioReagent assay 98.5-101.5% dry basis form crystalline powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white mp 215 °C solubility H2O: soluble SMILES string [H]O[H].NCCCC[C@H](N)C(O)=O InChI 1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1 InChI key HZRUTVAFDWTKGD-JEDNCBNOSA-N
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L-Lysine monohydrochloride
Empirical Formula (Hill Notation): C6H14N2O2 · HCl Linear Formula: H2N(CH2)4CH(NH2)CO2H·HCl CAS Number: 657-27-2 Molecular Weight: 182.65 Beilstein/REAXYS Number: 3563889 EC Number: 211-519-9 MDL number: MFCD00064564 PubChem Substance ID: 24896408 NACRES: NA.26
Кат. номер L5626-100G L5626-VAR L5626-1G-KC L5626-5KG L5626-500G L5626-1G L5626-1KG L5626-25G ApplicationL-lysine monohydrochloride has been used:- as a component in pre-fixative solution for electron microscopy
- as a component in blocking solution for immunohistochemistry(IHC)
- in the preparation of Periodate-lysine-paraformaldehyde (PLP) fixative for IHC
Packaging1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drumBiochem/physiol ActionsL-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.Параметрыgrade reagent grade Quality Level 200, assay 98% (HPLC) form powder application(s) immunohistochemistry: suitable, peptide synthesis: suitable color white to off-white mp 263 °C (dec.) (lit.) SMILES string OC([C@@H](N)CCCCN)=O.[H]Cl InChI 1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1 InChI key BVHLGVCQOALMSV-JEDNCBNOSA-N
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L-Lysine p-nitroanilide dihydrobromide
Empirical Formula (Hill Notation): C12H18N4O3 · 2HBr CAS Number: 40492-96-4 Molecular Weight: 428.12 MDL number: MFCD00050686 PubChem Substance ID: 24896389 NACRES: NA.26
Кат. номер L7002-1G L7002-250MG L7002-5G ApplicationL-Lysine p-nitroanilide may be used as a substrate to study the specificity and kinetics of lysine aminopeptidase(s) and various proteinases.Параметрыassay 98% (TLC) Quality Level 200, form powder application(s) ligand binding assay: suitable color off-white storage temp. 2-8°C SMILES string Br.NCCCC[C@H](N)C(=O)Nc1ccc(cc1)N(=O)=O InChI 1S/C12H18N4O3.BrH/c13-8-2-1-3-11(14)12(17)15-9-4-6-10(7-5-9)16(18)19;/h4-7,11H,1-3,8,13-14H2,(H,15,17);1H/t11-;/m0./s1 InChI key FJNCJWJSSUJZMS-MERQFXBCSA-N
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L-Methionine
Empirical Formula (Hill Notation): C5H11NO2S Linear Formula: CH3SCH2CH2CH(NH2)CO2H CAS Number: 63-68-3 Molecular Weight: 149.21 Beilstein/REAXYS Number: 1722294 EC Number: 200-562-9 MDL number: MFCD00063097 eCl@ss: 32160406 PubChem Substance ID: 24897343 NACRES: NA.26
Кат. номер M9625-VAR M9625-1G-KC M9625-100G M9625-5G M9625-1KG M9625-25G M9625-500G M9625-1G ApplicationL-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.Packaging5, 25, 100, 500 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionines metabolic product, glutathione, is known to regulate immune response and has antiviral action.ПараметрыQuality Level 200 grade reagent grade assay 98% (HPLC) form powder application(s) detection: suitable color white mp 284 °C (dec.) (lit.) SMILES string CSCC[C@H](N)C(O)=O InChI 1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 InChI key FFEARJCKVFRZRR-BYPYZUCNSA-N Gene Information rat ... Ggt1(116568)
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L-Methionine p-nitroanilide
Empirical Formula (Hill Notation): C11H15N3O3S CAS Number: 6042-04-2 Molecular Weight: 269.32 MDL number: MFCD00063424 PubChem Substance ID: 24896851 NACRES: NA.26
Кат. номер M3529-1G M3529-100MG M3529-250MG M3529-25MG Packaging100 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsL-Methionine p-nitroanilide is a hMetAP2 substrate.Параметрыassay 98% (TLC) Quality Level 200, form powder application(s) ligand binding assay: suitable color white to faint yellow storage temp. 20°C SMILES string CSCC[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O InChI 1S/C11H15N3O3S/c1-18-7-6-10(12)11(15)13-8-2-4-9(5-3-8)14(16)17/h2-5,10H,6-7,12H2,1H3,(H,13,15)/t10-/m0/s1 InChI key PLBWRAWSHVJPTL-JTQLQIEISA-N
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L-Methionine sulfone
Empirical Formula (Hill Notation): C5H11NO4S CAS Number: 7314-32-1 Molecular Weight: 181.21 Beilstein/REAXYS Number: 1725510 EC Number: 230-774-7 MDL number: MFCD00066020 PubChem Substance ID: 24896574 NACRES: NA.26
Кат. номер M0876-5G M0876-1G M0876-500MG Biochem/physiol ActionsL-Methionine sulfone may be used to study pupae development of the silkworm Bombyx mori L. L-Methionine sulfone may be used as a complexing agent to study conformational structures and stereospecificity of enzymes such as glutamate synthase and gamma-glutamyl transpeptidase.Параметрыassay 98% (TLC) Quality Level 200, form powder or crystals application(s) detection: suitable, peptide synthesis: suitable color white mp 275 °C SMILES string CS(=O)(=O)CC[C@H](N)C(O)=O InChI 1S/C5H11NO4S/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 InChI key UCUNFLYVYCGDHP-BYPYZUCNSA-N Gene Information rat ... Ggt1(116568)
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L-Methionine sulfoxide
Empirical Formula (Hill Notation): C5H11NO3S CAS Number: 3226-65-1 Molecular Weight: 165.21 Beilstein/REAXYS Number: 4129939 EC Number: 221-758-0 MDL number: MFCD00063093 PubChem Substance ID: 24896617 NACRES: NA.26
Кат. номер M1126-1G M1126-5G M1126-100MG M1126-500MG M1126-10MG Biochem/physiol ActionsL-Methionine sulfoxide, a structural analog of glutamate, may be used as a substrate to study the specificity and kinetics of various methionine sulfoxide reductase(s).Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M1126.pdf, Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,Параметрыassay 98% (TLC) Quality Level 200, form powder application(s) detection: suitable, peptide synthesis: suitable color white to off-white mp 255 °C SMILES string CS(=O)CC[C@H](N)C(O)=O InChI 1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m0/s1 InChI key QEFRNWWLZKMPFJ-YGVKFDHGSA-N Gene Information rat ... Ggt1(116568)
Safety Informationpictograms GHS07 signalword Warning hcodes H319 pcodes P305 + P351 + P338 Personal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Norleucine N8513-100MG
Empirical Formula (Hill Notation): C6H13NO2 Linear Formula: CH3(CH2)3CH(NH2)CO2H CAS Number: 327-57-1 Molecular Weight: 131.17 Beilstein/REAXYS Number: 1721750 EC Number: 206-321-4 MDL number: MFCD00064423 eCl@ss: 32160406 PubChem Substance ID: 24897682 NACRES: NA.26 ApplicationHighly purified internal standard for all amino acid analysis methods.Other NotesNon-essential amino acid.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N8513.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, product line BioReagent form powder or crystals application(s) detection: suitable color white mp >300 °C (lit.) suitability suitable for amino acid analysis SMILES string CCCC[C@H](N)C(O)=O InChI 1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 InChI key LRQKBLKVPFOOQJ-YFKPBYRVSA-N
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L-Norleucine
Empirical Formula (Hill Notation): C6H13NO2 Linear Formula: CH3(CH2)3CH(NH2)CO2H CAS Number: 327-57-1 Molecular Weight: 131.17 Beilstein/REAXYS Number: 1721750 EC Number: 206-321-4 MDL number: MFCD00064423 eCl@ss: 32160406 PubChem Substance ID: 24897796 NACRES: NA.26
Кат. номер N6877-10G N6877-5G N6877-1G N6877-100MG N6877-500MG Packaging1, 5, 10 g in poly bottleBiochem/physiol ActionsL-Norleucine is a synthetic amino acid commonly used as an internal standard.Other NotesNon-essential amino acid.ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) detection: suitable color white mp >300 °C (lit.) SMILES string CCCC[C@H](N)C(O)=O InChI 1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 InChI key LRQKBLKVPFOOQJ-YFKPBYRVSA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H317 pcodes P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Faceshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Norvaline
Empirical Formula (Hill Notation): C5H11NO2 Linear Formula: CH3CH2CH2CH(NH2)CO2H CAS Number: 6600-40-4 Molecular Weight: 117.15 Beilstein/REAXYS Number: 1721162 EC Number: 229-543-3 MDL number: MFCD00064421 eCl@ss: 32160406 PubChem Substance ID: 24897833 NACRES: NA.26
Кат. номер N7627-5G N7627-1G N7627-10G Packaging1, 5, 10 g in poly bottleBiochem/physiol ActionsL-Norvaline enhances NO production from activated macrophages.ПараметрыQuality Level 200, assay 99% (TLC) form powder application(s) detection: suitable color white mp >300 °C (lit.) SMILES string CCC[C@H](N)C(O)=O InChI 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 InChI key SNDPXSYFESPGGJ-BYPYZUCNSA-N
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L-Ornithine dihydrochloride
Empirical Formula (Hill Notation): C5H12N2O2 · 2HCl CAS Number: 6211-16-1 Molecular Weight: 205.08 Beilstein/REAXYS Number: 4538819 EC Number: 228-277-5 MDL number: MFCD00066571 PubChem Substance ID: 329766423 NACRES: NA.26
Кат. номер 75440-100G 75440-INTR 75440-5G 75440-25G Biochem/physiol ActionsL-Ornithine is a non-proteinogenic recycled component of the Urea Cycle leading to the production of arginine. L-ornithine is the starting compound for polyamine biosynthesis via ornithine decarboxylase.ПараметрыQuality Level 100, assay 99.0% (AT) form crystals optical activity []20/D +17±1°, c = 5% in H2O application(s) ligand binding assay: suitable ign. residue 0.1% (as SO4) color colorless mp 197-199 °C (dec.) anion traces sulfate (SO42-): 100 mg/kg cation traces As: 0.1 mg/kg, Cd: 5 mg/kg, Co: 5 mg/kg, Cu: 5 mg/kg, Fe: 5 mg/kg, NH4+: 100 mg/kg, Ni: 5 mg/kg, Pb: 5 mg/kg, Zn: 5 mg/kg SMILES string Cl.Cl.NCCC[C@H](N)C(O)=O InChI 1S/C5H12N2O2.2ClH/c6-3-1-2-4(7)5(8)9;;/h4H,1-3,6-7H2,(H,8,9);2*1H/t4-;;/m0../s1 InChI key HGBAVEGDXFHRQP-FHNDMYTFSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Ornithine L-aspartate salt
Empirical Formula (Hill Notation): C9H19N3O6 CAS Number: 3230-94-2 Molecular Weight: 265.26 EC Number: 221-772-7 MDL number: MFCD00058084 PubChem Substance ID: 329818920 NACRES: NA.26
Кат. номер O7125-100G O7125-25G O7125-5G Packaging25, 100 g in poly bottleBiochem/physiol ActionsL-Ornithine L-aspartate is a metabolite of arginine degradation by arginase. It has been shown to reduce blood ammonia concentrations by increasing ammoniadetoxification in the muscle and reducing the severity of hepatic encephalopathy in cirrhosis.Other NotesProduct of arginine degradation by arginaseПараметрыassay 98% (TLC) Quality Level 200, form powder color white to off-white storage temp. 2-8°C SMILES string NCCC[C@H](N)C(O)=O.N[C@@H](CC(O)=O)C(O)=O InChI 1S/C5H12N2O2.C4H7NO4/c6-3-1-2-4(7)5(8)9;5-2(4(8)9)1-3(6)7/h4H,1-3,6-7H2,(H,8,9);2H,1,5H2,(H,6,7)(H,8,9)/t4-;2-/m00/s1 InChI key IXUZXIMQZIMPSQ-ZBRNBAAYSA-N
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L-Ornithine monohydrochloride
Empirical Formula (Hill Notation): C5H12N2O2 · HCl CAS Number: 3184-13-2 Molecular Weight: 168.62 Beilstein/REAXYS Number: 3625847 EC Number: 221-678-6 MDL number: MFCD00064562 PubChem Substance ID: 24897960 NACRES: NA.26
Кат. номер 2540025 O2375-5G O2375-1G O2375-10MG O2375-1KG O2375-25G O2375-100G O2375-5KG ApplicationL-Ornithine monohydrochloride has been used to study the blocking effect of L-ornithine on the transport system that carries L-arginine for the overproduction of nitric oxide during lipopolysaccharide induced endotoxemia in rat model. It has also been used in decarboxylation test of amino acids.Packaging10 mg in glass bottle
5, 25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant polyamine observed in tumors such as breast carcinomas. Administration of L-ornithine is known to improve subjective index of sleep quality. L-ornithine reduces the cortisol/DHEA-S (dehydroepiandrosterone) ratio, that is associated with stress. In mice, L-ornithine is found to affect the levels of plasma growth hormone, corticosterone and melatonin levels in mice.Other NotesProduct of arginine degradation by arginase
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. O2375.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 99% form powder application(s) cell analysis: suitable impurities ammonia and citrulline, essentially free color white SMILES string Cl.NCCC[C@H](N)C(O)=O InChI 1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1 InChI key GGTYBZJRPHEQDG-WCCKRBBISA-N
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L-Phenylalaninamide
Empirical Formula (Hill Notation): C9H12N2O CAS Number: 5241-58-7 Molecular Weight: 164.20 Beilstein/REAXYS Number: 6270941 MDL number: MFCD00038146 PubChem Substance ID: 24898253 NACRES: NA.26
Кат. номер P1883-5G P1883-1G P1883-500MG Biochem/physiol ActionsL-Phenylalaninamide is a chiral selector.Параметрыassay 98% Quality Level 200, form powder application(s) detection: suitable color white to off-white mp 92.8 °C SMILES string N[C@@H](Cc1ccccc1)C(N)=O InChI 1S/C9H12N2O/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H2,11,12)/t8-/m0/s1 InChI key OBSIQMZKFXFYLV-QMMMGPOBSA-N
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L-Phenylalanine
Empirical Formula (Hill Notation): C9H11NO2 Linear Formula: C6H5CH2CH(NH2)CO2H CAS Number: 63-91-2 Molecular Weight: 165.19 Beilstein/REAXYS Number: 1910408 EC Number: 200-568-1 MDL number: MFCD00064227 eCl@ss: 32160406 PubChem Substance ID: 24898274 NACRES: NA.26
Кат. номер P2126-VAR P2126-1KG P2126-100G P2126-1G P2126-500G P2126-1G-KC P2126-25G P2126-250G P2126-5G P2126-10G ApplicationL-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.Packaging1 kg in poly bottle
100, 500 g in poly bottleBiochem/physiol ActionsL-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.Параметрыgrade reagent grade Quality Level 200, assay 98% form powder or crystals application(s) detection: suitable color white to off-white mp 270-275 °C (dec.) (lit.) solubility 1 M NH4OH: 50 mg/mL, clear, colorless SMILES string N[C@@H](Cc1ccccc1)C(O)=O InChI 1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1 InChI key COLNVLDHVKWLRT-QMMMGPOBSA-N Gene Information human ... CA1(759), CA14(23632), CA2(760), CA4(762), CA5A(763), CA7(766)
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L-Phenylalanine methyl ester hydrochloride
Empirical Formula (Hill Notation): C10H13NO2 · HCl Linear Formula: C6H5CH2CH(NH2)COOCH3 · HCl CAS Number: 7524-50-7 Molecular Weight: 215.68 Beilstein/REAXYS Number: 3597948 EC Number: 231-383-4 MDL number: MFCD00012489 eCl@ss: 32160406 PubChem Substance ID: 24898239 NACRES: NA.22
Кат. номер P17202-10G P17202-25G P17202-2.5G ПараметрыQuality Level 100, assay 98% form powder or crystals optical activity []20/D +32.4°, c = 2 in ethanol reaction suitability reaction type: solution phase peptide synthesis color white mp 158-162 °C (lit.) SMILES string Cl.COC(=O)[C@@H](N)Cc1ccccc1 InChI 1S/C10H13NO2.ClH/c1-13-10(12)9(11)7-8-5-3-2-4-6-8;/h2-6,9H,7,11H2,1H3;1H/t9-;/m0./s1 InChI key SWVMLNPDTIFDDY-FVGYRXGTSA-N
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L-Pipecolic acid
Empirical Formula (Hill Notation): C6H11NO2 CAS Number: 3105-95-1 Molecular Weight: 129.16 Beilstein/REAXYS Number: 81093 EC Number: 221-462-1 MDL number: MFCD00005981 PubChem Substance ID: 24898330 NACRES: NA.26
Кат. номер P2519-250MG P2519-25MG P2519-100MG P2519-1G General descriptionL-pipecolic acid (piperidine-2-carboxylic acid) is a nitrogen-containing heterocyclic compound. It is an imino acid. Its molecular weight is 129.2.ApplicationL-Pipecolic acid has been used as a standard for the quantification by gas chromatography-mass spectrometry (GC-MS).Packaging100, 250 mg in glass insert
1 g in glass bottleBiochem/physiol ActionsL-pipecolic acid is implicated in Zellweger syndrome. Pipecolic acid is also a plant defence metabolite. It is a signaling compound essential for systemic acquired resistance (SAR).
L-Pipecolic acid is a lysine metabolite; defect in its catabolism is involved in hyperpipecolic acidemia, cerebro-hepato-renal syndrome, neonatal onset adrenoleukodystrophy, and infantile Refsum disease.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P2519.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 99% (titration) form powder application(s) GC/MS: suitable color white mp 272 °C (lit.) SMILES string OC(=O)[C@@H]1CCCCN1 InChI 1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1 InChI key HXEACLLIILLPRG-YFKPBYRVSA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 - H335 pcodes P302 + P352 - P305 + P351 + P338 Target Organs Respiratory system Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
L-Proline
Empirical Formula (Hill Notation): C5H9NO2 CAS Number: 147-85-3 Molecular Weight: 115.13 Beilstein/REAXYS Number: 80810 EC Number: 205-702-2 MDL number: MFCD00064318 eCl@ss: 32160406 PubChem Substance ID: 24898677
Кат. номер P5607-1KG P5607-100G P5607-25KG P5607-25G P5607-BR ApplicationL-proline has been used as a component of high-glucose-Dulbecco′s modified Eagle′s medium (HG-DMEM) for chondrocyte differentiation and for the culture of chondrocyte-like cells. It has also been used as a component of yeast nitrogen base for yeast cultures.Packaging25, 100 g in poly bottle
25 kg in poly drum
1 kg in poly bottleBiochem/physiol ActionsProline is a cyclic, non-essential, hydrophobic amino acid. It is a proteinogenic amino acid which is crucial for primary metabolism. In peptide chains, proline residues confer structural constraints and enhance the susceptibility of proximal peptide bonds to protease activity.Параметрыbiological source non-animal source Quality Level 200, Agency/Method meets EP testing specifications, meets USP testing specifications assay 98.5-101.0% dry basis form powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white mp 228 °C (dec.) (lit.) solubility H2O: 50 mg/mL Featured Industry Pharmaceutical (small molecule) SMILES string OC(=O)[C@@H]1CCCN1 InChI 1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 InChI key ONIBWKKTOPOVIA-BYPYZUCNSA-N
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L-Proline -naphthylamide hydrochloride
Empirical Formula (Hill Notation): C15H16N2O · HCl CAS Number: 97216-16-5 Molecular Weight: 276.76 MDL number: MFCD00038937 PubChem Substance ID: 24898192 NACRES: NA.26
Кат. номер P1380-1G P1380-100MG P1380-250MG P1380-500MG Biochem/physiol ActionsL-Proline β-naphthylamide is a substrate used for testing enzyme activity.PackagingBottomless glass bottle. Contents are inside inserted fused cone.ПараметрыQuality Level 200, assay 99% form powder application(s) ligand binding assay: suitable color white to off-white storage temp. 20°C SMILES string Cl.O=C(Nc1ccc2ccccc2c1)[C@@H]3CCCN3 InChI 1S/C15H16N2O.ClH/c18-15(14-6-3-9-16-14)17-13-8-7-11-4-1-2-5-12(11)10-13;/h1-2,4-5,7-8,10,14,16H,3,6,9H2,(H,17,18);1H/t14-;/m0./s1 InChI key UKXYCTFKKXKIPY-UQKRIMTDSA-N
Safety Informationpictograms GHS08 signalword Danger hcodes H350 pcodes P201 - P308 + P313 Personal Protective Equipment Eyeshields,, Faceshields,, Gloves,, type P1 (EN143) respirator filter,, type P3 (EN 143) respirator cartridges, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Proline p-nitroanilide trifluoroacetate salt
Empirical Formula (Hill Notation): C11H13N3O3 · C2HF3O2 CAS Number: 108321-19-3 Molecular Weight: 349.26 MDL number: MFCD00069671 eCl@ss: 32160406 PubChem Substance ID: 329820223 NACRES: NA.26
Кат. номер P5267-1G P5267-2G P5267-250MG General descriptionProline p-nitroanilide (P-pNA) is a colorimetric substrate for prolyl aminopeptidase (proline iminopeptidase), an enzyme that releases proline from the N-terminus of small peptides.ApplicationProline p-nitroanilide (P-pNA) has been used as a substrate for prolyl aminopeptidase (proline iminopeptidase) from cabbage leaves.ПараметрыQuality Level 200, assay 99% (TLC) form powder application(s) ligand binding assay: suitable color white to yellow storage temp. 2-8°C SMILES string OC(=O)C(F)(F)F.[O-][N+](=O)c1ccc(NC(=O)[C@@H]2CCCN2)cc1 InChI 1S/C11H13N3O3.C2HF3O2/c15-11(10-2-1-7-12-10)13-8-3-5-9(6-4-8)14(16)17;3-2(4,5)1(6)7/h3-6,10,12H,1-2,7H2,(H,13,15);(H,6,7)/t10-;/m0./s1 InChI key KYRVEVYREUUAKH-PPHPATTJSA-N
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L-Proline t-butyl ester
Empirical Formula (Hill Notation): C9H17NO2 CAS Number: 2812-46-6 Molecular Weight: 171.24 EC Number: 220-558-0 MDL number: MFCD00037879 eCl@ss: 32160406 PubChem Substance ID: 24898875 NACRES: NA.26
Кат. номер P7764-1G P7764-5G P7764-100MG P7764-250MG Параметрыassay 98% Quality Level 200, form liquid color clear colorless to faint yellow storage temp. 2-8°C SMILES string CC(C)(C)OC(=O)[C@@H]1CCCN1 InChI 1S/C9H17NO2/c1-9(2,3)12-8(11)7-5-4-6-10-7/h7,10H,4-6H2,1-3H3/t7-/m0/s1 InChI key XJJBXZIKXFOMLP-ZETCQYMHSA-N
Safety Informationpictograms GHS05,GHS07 signalword Danger hcodes H302 - H315 - H318 - H335 pcodes P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310 Target Organs Respiratory system Personal Protective Equipment Eyeshields,, Faceshields,, Gloves,, type ABEK (EN14387) respirator filter, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Pyroglutamic acid 2-naphthylamide
Empirical Formula (Hill Notation): C15H14N2O2 CAS Number: 22155-91-5 Molecular Weight: 254.28 Beilstein/REAXYS Number: 5066652 EC Number: 244-809-9 MDL number: MFCD00055911 PubChem Substance ID: 329820238 NACRES: NA.26
Кат. номер P5891-1G P5891-5G P5891-500MG P5891-25MG P5891-100MG ApplicationA substrate for pyroglutamate aminopeptidase. Used for differentiation of Group A streptococci and enterococci from other streptococci.Biochem/physiol ActionsPyroglutamic acid is known to participate in the gamma-glutamyl cycle. Recent studies show that a congenital metabolic error was associated with increased pyroglutamic excretion in urine.PackagingBottomless glass bottle. Contents are inside inserted fused cone.ПараметрыQuality Level 200, assay 99% (TLC) form powder application(s) ligand binding assay: suitable color white to off-white storage temp. 2-8°C SMILES string O=C1CC[C@H](N1)C(=O)Nc2ccc3ccccc3c2 InChI 1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)/t13-/m0/s1 InChI key BZEPQNMASTUAMY-ZDUSSCGKSA-N
Safety Informationpictograms GHS09 signalword Warning hcodes H400 pcodes P273 Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR UN 3077 9 / PGIII WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Serine
Empirical Formula (Hill Notation): C3H7NO3 Linear Formula: HOCH2CH(NH2)CO2H CAS Number: 56-45-1 Molecular Weight: 105.09 Beilstein/REAXYS Number: 1721404 EC Number: 200-274-3 MDL number: MFCD00064224 eCl@ss: 32160406 PubChem Substance ID: 24899605 NACRES: NA.26
Кат. номер S4500-1G-KC S4500-1KG S4500-100G S4500-1G S4500-25G S4500-10MG S4500-5G ApplicationL-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.Packaging1, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.
Precursor of glycine by serine hydroxymethyltransferase.Legal InformationReagentPlus is a registered trademark of Sigma-Aldrich Co. LLCПараметрыproduct line ReagentPlus® Quality Level 200, assay 99% (HPLC) form powder application(s) detection: suitable color white to off-white mp 222 °C (dec.) (lit.) solubility H2O: 50 mg/mL, clear, colorless storage temp. room temp SMILES string N[C@@H](CO)C(O)=O InChI 1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1 InChI key MTCFGRXMJLQNBG-REOHCLBHSA-N
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L-Serine -naphthylamide
Empirical Formula (Hill Notation): C13H14N2O2 CAS Number: 888-74-4 Molecular Weight: 230.26 MDL number: MFCD00080939 PubChem Substance ID: 24899611 NACRES: NA.26
Кат. номер S4630-1G S4630-100MG Параметрыassay 98% (TLC) Quality Level 200, form powder color off-white storage temp. 20°C SMILES string N[C@@H](CO)C(=O)Nc1ccc2ccccc2c1 InChI 1S/C13H14N2O2/c14-12(8-16)13(17)15-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12,16H,8,14H2,(H,15,17)/t12-/m0/s1 InChI key JOPLDMLMXHNTAX-LBPRGKRZSA-N
Safety Informationpictograms GHS08 signalword Warning hcodes H351 pcodes P201 - P308 + P313 Personal Protective Equipment Eyeshields,, Gloves,, type P1 (EN143) respirator filter,, type P3 (EN 143) respirator cartridges, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Serine benzyl ester benzenesulfonate (salt)
Empirical Formula (Hill Notation): C10H13NO3 · C6H6O3S CAS Number: 3695-68-9 Molecular Weight: 353.39 MDL number: MFCD06201000 PubChem Substance ID: 329747993 NACRES: NA.22
Кат. номер 4934-VAR-F 4934-25G-F 4934-5G-F ПараметрыQuality Level 100, assay 98.0% (HPLC) form powder or flakes reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color colorless to white SMILES string OS(=O)(=O)c1ccccc1.N[C@@H](CO)C(=O)OCc2ccccc2 InChI 1S/C10H13NO3.C6H6O3S/c11-9(6-12)10(13)14-7-8-4-2-1-3-5-8;7-10(8,9)6-4-2-1-3-5-6/h1-5,9,12H,6-7,11H2;1-5H,(H,7,8,9)/t9-;/m0./s1 InChI key AJKFQGHWMCPNTI-FVGYRXGTSA-N
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L-Serine benzyl ester hydrochloride
Empirical Formula (Hill Notation): C10H13NO3 · HCl CAS Number: 60022-62-0 Molecular Weight: 231.68 MDL number: MFCD00038955 PubChem Substance ID: 24899663 NACRES: NA.26
Кат. номер S5633-25G S5633-5G S5633-1G Параметрыassay 99% (TLC) Quality Level 200, form powder color white storage temp. 20°C SMILES string Cl.N[C@@H](CO)C(=O)OCc1ccccc1 InChI 1S/C10H13NO3.ClH/c11-9(6-12)10(13)14-7-8-4-2-1-3-5-8;/h1-5,9,12H,6-7,11H2;1H/t9-;/m0./s1 InChI key MGZWCDQAKCHOBX-FVGYRXGTSA-N
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