Cell Culture Supplements & Reagents
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L-Asparagine
Empirical Formula (Hill Notation): C4H8N2O3 Linear Formula: H2NCOCH2CH(NH2)CO2H CAS Number: 70-47-3 Molecular Weight: 132.12 Beilstein/REAXYS Number: 1723527 EC Number: 200-735-9 MDL number: MFCD00064401 eCl@ss: 32160406 PubChem Substance ID: 24890464 NACRES: NA.26
Кат. номер A0884-1G-KC A0884-1KG A0884-100G A0884-10MG A0884-25G A0884-1G A0884-500G ApplicationL-asparagine has been used:- to identify and quantify free amino acids released upon oxidation of proteins and peptides by hydroxyl radicals
- to study the effects of amino acids in promoting food consumption in Drosophila melanogaster
- to study non-enzymatic gluconeogenesis
Packaging25, 100, 500 g in poly bottle
10 mg in glass bottle
1 kg in poly bottleBiochem/physiol ActionsL-asparagine is an uncharged derivative of aspartate. It possesses a polar side chain and is a non-essential amino acid.ПараметрыQuality Level 300, assay 98% (HPLC) form powder application(s) detection: suitable color white mp 235 °C (dec.) (lit.) SMILES string N[C@@H](CC(N)=O)C(O)=O InChI 1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1 InChI key DCXYFEDJOCDNAF-REOHCLBHSA-N
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L-Asparagine monohydrate
Empirical Formula (Hill Notation): C4H8N2O3 · H2O Linear Formula: NH2COCH2CH(NH2)COOH · H2O CAS Number: 5794-13-8 Molecular Weight: 150.13 Beilstein/REAXYS Number: 1723527 EC Number: 200-735-9 MDL number: MFCD00151038 PubChem Substance ID: 24891338
Кат. номер A8381-100G A8381-1KG A8381-10G A8381-1G A8381-25G General descriptionAsparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues. Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt. It is also present in senescing leaves and germinating seeds.ApplicationL-Asparagine monohydrate has been used:- as a component of Sautons and chelated Sautons media for mycobacterial growth
- to test its effect in the induction of Ca2+ flux in rice roots using aequorin luminescence imaging
- as a component of fermentation medium for the Blakeslea trispora spores
Packaging100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsAsparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport. Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods. Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation.
L-Asparagine, a proteinogenic amino acid, is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies and in cell culture based research.ПараметрыQuality Level 200, biological source synthetic assay 99% (TLC) form powder application(s) cell analysis: suitable, peptide synthesis: suitable color white to off-white mp 233-235 °C (lit.) SMILES string [H]O[H].N[C@@H](CC(N)=O)C(O)=O InChI 1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1 InChI key RBMGJIZCEWRQES-DKWTVANSSA-N
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L-Aspartic acid
Empirical Formula (Hill Notation): C4H7NO4 Linear Formula: HO2CCH2CH(NH2)CO2H CAS Number: 56-84-8 Molecular Weight: 133.10 Beilstein/REAXYS Number: 1723530 EC Number: 200-291-6 MDL number: MFCD00002616 eCl@ss: 32160406 PubChem Substance ID: 24277948 NACRES: NA.26
Кат. номер A9256-10MG A9256-1G-KC A9256-5KG A9256-1G A9256-10MG-KC A9256-1KG A9256-500G A9256-100G A9256-5G A9256-25G ApplicationL-aspartic acid has been used as one of the components of synthetic drop out media for culturing budding yeast. It has also been used to study non-enzymatic gluconeogenesis.Packaging1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drumBiochem/physiol ActionsPrincipal neurotransmitter for fast synaptic excitation.
Aspartic acid is a non-essential amino acid. It is involved in the Urea cycle, Krebs cycle and in DNA metabolism.Параметрыgrade reagent grade Quality Level 200, assay 98% (HPLC) form powder, crystals or chunks color white to off-white mp >300 °C (dec.) (lit.) solubility H2O: 5 mg/mL, 0.5 M HCl: 50 mg/mL (with heat), 1 M NaOH: 50 mg/mL SMILES string N[C@@H](CC(O)=O)C(O)=O InChI 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1 InChI key CKLJMWTZIZZHCS-REOHCLBHSA-N Gene Information human ... CA1(759), CA2(760)
rat ... Grin2a(24409)
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L-Aspartic acid -(7-amido-4-methylcoumarin)
Empirical Formula (Hill Notation): C14H14N2O5 CAS Number: 133628-73-6 Molecular Weight: 290.27 MDL number: MFCD00236804 PubChem Substance ID: 24890500 NACRES: NA.26
Кат. номер A1057-50MG A1057-10MG Biochem/physiol ActionsL-Aspartic acid-β-7-amido-4-methylcoumarin is sensitive and specific fluorogenic substrate used to assay for lysosomal glycoasparaginase (aspartylglucosaminidase) activity and the diagnosis of aspartylglucosaminuria.
L-Aspartic acid β-(7-amido-4-methylcoumarin) is used as a fluorogenic substrate for studying the specificity and kinetics of lysosomal glycoasparaginase(s) (aspartylglucosaminidase) and L-asparaginase(s).ПараметрыQuality Level 200, assay 98% form powder application(s) ligand binding assay: suitable color white to off-white storage temp. 20°C SMILES string CC1=CC(=O)Oc2cc(NC(=O)C[C@H](N)C(O)=O)ccc12 InChI 1S/C14H14N2O5/c1-7-4-13(18)21-11-5-8(2-3-9(7)11)16-12(17)6-10(15)14(19)20/h2-5,10H,6,15H2,1H3,(H,16,17)(H,19,20)/t10-/m0/s1 InChI key ARZPQBJTLVVDNP-JTQLQIEISA-N
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L-Aspartic acid -benzyl ester
Empirical Formula (Hill Notation): C11H13NO4 Linear Formula: C6H5CH2OCOCH2CH(NH2)COOH CAS Number: 2177-63-1 Molecular Weight: 223.23 Beilstein/REAXYS Number: 1983183 EC Number: 218-541-8 MDL number: MFCD00037208 PubChem Substance ID: 24891628 NACRES: NA.26
Кат. номер B2129-25G B2129-1G B2129-5G ApplicationL-Aspartic acid β-benzyl ester is used in the synthesis of peptides with a 1,4-diazepine-2,5-dione ring structure and in development of block copolymers.Параметрыassay 98% Quality Level 200, form powder application(s) peptide synthesis: suitable color white mp 225 °C storage temp. 20°C SMILES string N[C@@H](CC(=O)OCc1ccccc1)C(O)=O InChI 1S/C11H13NO4/c12-9(11(14)15)6-10(13)16-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,14,15)/t9-/m0/s1 InChI key VGALFAWDSNRXJK-VIFPVBQESA-N
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L-Aspartic acid -hydroxamate
Empirical Formula (Hill Notation): C4H8N2O4 CAS Number: 1955-68-6 Molecular Weight: 148.12 MDL number: MFCD00050389 eCl@ss: 32160406 PubChem Substance ID: 24891095 NACRES: NA.26
Кат. номер A6508-1G-PW A6508-100MG A6508-1G A6508-100MG-PW ПараметрыQuality Level 200, assay >98% form powder application(s) detection: suitable color white to yellow storage temp. 20°C SMILES string N[C@@H](CC(=O)NO)C(O)=O InChI 1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1 InChI key ZBYVTTSIVDYQSO-REOHCLBHSA-N
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L-Aspartic acid 4-tert-butyl ester 11214-5G
Empirical Formula (Hill Notation): C8H15NO4 CAS Number: 3057-74-7 Molecular Weight: 189.21 Beilstein/REAXYS Number: 4671089 EC Number: 221-292-8 MDL number: MFCD00038577 PubChem Substance ID: 57646897 NACRES: NA.22 ПараметрыQuality Level 100, assay 98.0% (TLC) optical activity []20/D 9±2°, c = 2% in methanol: water (4:1) reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color white SMILES string CC(C)(C)OC(=O)C[C@H](N)C(O)=O InChI 1S/C8H15NO4/c1-8(2,3)13-6(10)4-5(9)7(11)12/h5H,4,9H2,1-3H3,(H,11,12)/t5-/m0/s1 InChI key MXWMFBYWXMXRPD-YFKPBYRVSA-N
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L-Aspartic acid hemimagnesium salt dihydrate
Empirical Formula (Hill Notation): C8H12MgN2O8 · 2H2O Linear Formula: [HOOCCH(NH2)CH2COO]2Mg · 2H2O CAS Number: 215533-00-9 Molecular Weight: 324.53 Beilstein/REAXYS Number: 5178578 MDL number: MFCD00044935 eCl@ss: 32160406 PubChem Substance ID: 329749340 NACRES: NA.77
Кат. номер 11260-VAR 11260-100G 11260-500G ПараметрыQuality Level 200, assay 97.0% (KT) form powder or crystals optical activity []20/D +20±1°, c = 8% in 6 M HCl application(s) peptide synthesis: suitable color white to faint beige SMILES string [Mg++].N[C@@H](CC(O)=O)C([O-])=O.N[C@@H](CC(O)=O)C([O-])=O InChI 1S/2C4H7NO4.Mg/c2*5-2(4(8)9)1-3(6)7;/h2*2H,1,5H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*2-;/m00./s1 InChI key RXMQCXCANMAVIO-CEOVSRFSSA-L
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L-Aspartic acid potassium salt
Empirical Formula (Hill Notation): C4H6KNO4 Linear Formula: HO2CCH2CH(NH2)CO2K CAS Number: 1115-63-5 Molecular Weight: 171.19 EC Number: 214-226-4 MDL number: MFCD00063085 eCl@ss: 32160406 PubChem Substance ID: 24891105 NACRES: NA.77
Кат. номер A6558-100G A6558-25G A6558-1KG A6558-5G A6558-5KG General descriptionL-aspartic acid is a non-essential amino acid.ApplicationL-Aspartic acid potassium salt has been used:- to prepare perforated patch-clamp intracellular solution
- in serum glutamate–oxaloacetate transaminase (SGOT) assay
- as a component in an internal solution (IS) for mitoflash assay to detect mitochondrial flashes in permeabilized cells
Packaging25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsL-Aspartic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist.
Potassium aspartate is capable of preventing ventricular arrhythmia in ischemic rabbit heart by decreasing transmural repolarization dispersion (TDR).
Principal neurotransmitter for fast synaptic excitation.ПараметрыQuality Level 200, assay 98% (HPLC) form powder application(s) ligand binding assay: suitable color white SMILES string N[C@H](C([O-])=O)CC(O)=O.[K+] InChI 1S/C4H7NO4.K/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H,6,7)(H,8,9);/q;+1/p-1/t2-;/m0./s1 InChI key TXXVQZSTAVIHFD-DKWTVANSSA-M
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L-Aspartic acid sodium salt monohydrate
Empirical Formula (Hill Notation): C4H6NNaO4 · H2O Linear Formula: HO2CCH2CH(NH2)CO2Na · H2O CAS Number: 323194-76-9 Molecular Weight: 173.10 Beilstein/REAXYS Number: 6101944 EC Number: 223-264-0 MDL number: MFCD00152960 eCl@ss: 32160406 PubChem Substance ID: 24891129 NACRES: NA.32
Кат. номер A6683-25G A6683-1KG A6683-100G General descriptionAspartic acid is a non-essential amino acid. L-Aspartic acid is a dicarboxylic amino acid, which is involved in the synthesis of nerve cells proteins. It also stimulates the depolarization of nerve cell membranes. L-Aspartic acid acts as an amine donor for transamination reaction.ApplicationL-Aspartic acid sodium salt monohydrate has been as a component of reservoir solution for crystallization.Biochem/physiol ActionsSelective outflow of L-aspartic acid across the blood-brain barrier controls the level of L and D aspartic acid in the brain. Increased levels of L-aspartic acid in the brain results in excitatory neurotoxicity. Recent studies highlight that racemization of L-aspartic acid is followed by the determination of D:L ratio to estimate the age of an individual.
Principal neurotransmitter for fast synaptic excitation.ПараметрыQuality Level 200, assay 98% (TLC) form powder color white SMILES string [Na+].[H]O[H].N[C@@H](CC(O)=O)C([O-])=O InChI 1S/C4H7NO4.Na.H2O/c5-2(4(8)9)1-3(6)7;;/h2H,1,5H2,(H,6,7)(H,8,9);;1H2/q;+1;/p-1/t2-;;/m0../s1 InChI key PPTHNBYUFXSJPS-JIZZDEOASA-M Gene Information human ... GRIN2A(2903)
rat ... GRIN2A(14811)
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L-C-Propargylglycine
Empirical Formula (Hill Notation): C5H7NO2 CAS Number: 23235-01-0 Molecular Weight: 113.11 Beilstein/REAXYS Number: 2347861 MDL number: MFCD00077855 eCl@ss: 32160406 PubChem Substance ID: 57652892 NACRES: NA.26
Кат. номер 81838-250MG 81838-50MG ApplicationReagent for the irreversible inactivation of γ-cystathionase; affinity labeling reagent for γ-cystathionase and other enzymes; peptides containing this amino acid can be tritiated to high specific radioactivityBiochem/physiol ActionsL-C-Propargylglycine, a specific inhibitor of H(2)S synthase of cystathionine-γ-lyase (CSE), may be used to study the role of H2S in regulation of biological processes.
L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), is useful in studies of hydrogen sulphide synthesis and bioactivity.ПараметрыQuality Level 100, assay 99.0% (TLC) form powder application(s) peptide synthesis: suitable color white mp 235-239 °C storage temp. 2-8°C SMILES string N[C@@H](CC#C)C(O)=O InChI 1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1 InChI key DGYHPLMPMRKMPD-BYPYZUCNSA-N
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L-Canavanine
Empirical Formula (Hill Notation): C5H12N4O3 CAS Number: 543-38-4 Molecular Weight: 176.17 MDL number: MFCD00055781 PubChem Substance ID: 24892427 NACRES: NA.26
Кат. номер C1625-1G C1625-100MG C1625-250MG C1625-25MG Packaging100, 250 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsCanavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,Параметрыbiological source Canavalia ensiformis Quality Level 200, assay 98% (TLC) form powder application(s) detection: suitable color white to yellow solubility H2O: <100 mg/mL storage temp. 2-8°C SMILES string N[C@@H](CCONC(N)=N)C(O)=O InChI 1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1 InChI key FSBIGDSBMBYOPN-VKHMYHEASA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H302 + H312 + H332 pcodes P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
L-Carnitine 11242008001
General descriptionEnzymatic UV-Test with a linearity in the range of 5.6 - 112 μM L-carnitine in the test solution.ApplicationDetermination of L-carnitine in seminal plasma, serum, or urine in life science research applications.Biochem/physiol ActionsL-carnitine is an abundant amino acid present in red meat. Its trimethylamine structure has similarity to that of choline. The major source of this amino acid is by dietary ingestion. In mammals, it is also endogenously produced from lysine. It participates in the transport of fatty acids into the mitochondrial compartment. It produces trimethylamine-N-oxide (TMAO) and promotes atherosclerosis.Packaging1 kit containing 6 componentsPrincipleL-Carnitine is acetylated to acetyl carnitine by acetyl coenzyme A (acetyl CoA) in the presence of the enzyme carnitine acetyl transferase (CAT). The resulting coenzyme A (CoA) is acetylated back to acetyl CoA in the presence of adenosine-5-triphosphate (ATP) and acetate, catalyzed by the enzyme acetyl CoA synthetase (ACS). This results in the formation of adenosine-5-monophosphate (AMP) and inorganic pyrophosphate (PPi). In the presence of ATP, supported by myokinase (MK), AMP forms twice the amount of adenosine-5-diphosphate (ADP). This is converted in the following reaction with phosphoenol pyruvate (PEP) in the presence of pyruvate kinase (PK). The pyruvate formed is reduced to L-lactate by reduced nicotinamide adenine dinucleotide (NADH) in the presence of lactate dehydrogenase (LDH). The amount of NADH consumed during the reaction is equivalent to half the amount of L-carnitine. NADH is measured spectroscopically at 340 nm.Preparation NoteStorage conditions (working solution): Note:- After reconstitution, the solution 1 is stable for 4 days at 2 to 8 °C.
- Bring solution 1 to 15 to 25 °C prior to use.
- After reconstitution, the suspension 2 is stable for 3 months at 2 to 8 °C.
Other NotesFor life science research only. Not for use in diagnostic procedures.Параметрыusage sufficient for ~3 x 10 determinations (test-combination), sufficient for ~3 x 10 tests Торговая марка Roche shipped in wet ice storage temp. 2-8°C
Safety Informationpictograms GHS05 signalword Danger hcodes H318 - H412 pcodes P273 - P280 - P305 + P351 + P338 + P310 - P501 RIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F does not flash Flash Point C does not flash Узнать цену -
L-Carnitine hydrochloride
Empirical Formula (Hill Notation): C7H15NO3 · HCl Linear Formula: (CH3)3N+CH2CH(OH)CH2CO2H · Cl- CAS Number: 6645-46-1 Molecular Weight: 197.66 EC Number: 229-663-6 MDL number: MFCD00066100 PubChem Substance ID: 24892246 NACRES: NA.79
Кат. номер C0283-10MG C0283-1G C0283-5G C0283-25G C0283-100G ApplicationL-Carnitine hydrochloride has been used to study ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5. It has also been used to allow the entry of palmitic acid into the mitochondria.Packaging10 mg in glass bottle
1, 5, 25, 100 g in poly bottleBiochem/physiol ActionsCarnitine is biosynthesized from lysine. It might be associated with the energy production from branched chain amino acids.
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.ПараметрыQuality Level 200, biological source synthetic assay 98% form powder application(s) cell analysis: suitable color white mp 142 °C SMILES string [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O InChI 1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1 InChI key JXXCENBLGFBQJM-FYZOBXCZSA-N
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L-Carnitine inner salt
Empirical Formula (Hill Notation): C7H15NO3 Linear Formula: (CH3)3N+CH2CH(OH)CH2COO- CAS Number: 541-15-1 Molecular Weight: 161.20 Beilstein/REAXYS Number: 4292315 EC Number: 208-768-0 MDL number: MFCD00038747 PubChem Substance ID: 24892238 NACRES: NA.79
Кат. номер C0158-25G C0158-1G C0158-5G C0158-100G ApplicationL-Carnitine inner salt has been used as a component of an assay medium for Seahorse XF mitochondrial stress assay. It has also been orally administered to tumor-bearing mice, in order to study its effect on the regulation of peroxisome proliferator-activated receptor and thereby to analyse liver inflammatory response.Packaging1, 5, 25, 100 g in poly bottleBiochem/physiol ActionsCarnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment. In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branched chain amino acids.
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.ПараметрыQuality Level 200, biological source synthetic assay 98% form powder application(s) cell analysis: suitable, detection: suitable color white mp 197-212 °C (lit.) SMILES string C[N+](C)(C)C[C@H](O)CC([O-])=O InChI 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1 InChI key PHIQHXFUZVPYII-ZCFIWIBFSA-N
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L-Carnosine
Empirical Formula (Hill Notation): C9H14N4O3 CAS Number: 305-84-0 Molecular Weight: 226.23 Beilstein/REAXYS Number: 87671 EC Number: 206-169-9 MDL number: MFCD00005207 PubChem Substance ID: 24893178 NACRES: NA.26
Кат. номер C9625-25G C9625-100G C9625-5G C9625-10MG C9625-1G C9625-500MG Amino Acid SequenceAla-HisApplicationL-Carnosine has been used to study its effects as an antioxidant on meat quality of pigs. It has also been used to study its effects on brain injury in a rat intracerebral hemorrhage model.Packaging5, 25, 100 g in poly bottle
10 mg in poly bottleBiochem/physiol ActionsL-Carosine is a dipeptide found at millimolar concentration in brain, muscle and the lens of the eye. In model systems it is a potent antioxidant that scavenges oxygen free radicals and transition metal ions. It blocks protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes such as acetaldehyde, formaldehyde, and malondialdehyde, the primary product of lipid peroxidation. It also inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibits the formation of toxic advanced glycation end products (AGE). These activities make it of interest in studies of aging, atherosclerosis, Alzheimers disease, and the secondary effects of diabetes.
Dipeptide with potent antioxidant and antiglycation activity; blocks nonenzymatic glycosylation and protein cross-linking induced by reactive aldehydes.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C9625.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,Параметрыassay ~99% Quality Level 200, form crystalline application(s) cell analysis: suitable color white to off-white mp 253 °C (dec.) (lit.) storage temp. 20°C SMILES string NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O InChI 1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1 InChI key CQOVPNPJLQNMDC-ZETCQYMHSA-N Gene Information human ... CA1(759), CA2(760)
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L-Citrulline
Empirical Formula (Hill Notation): C6H13N3O3 CAS Number: 372-75-8 Molecular Weight: 175.19 Beilstein/REAXYS Number: 1725416 EC Number: 206-759-6 MDL number: MFCD00064397 PubChem Substance ID: 24892975 NACRES: NA.32
Кат. номер C7629-500G C7629-25G C7629-1G C7629-10MG C7629-1KG C7629-5G C7629-10MG-KC C7629-100G ApplicationL-Citrulline has been used in ultra-performance liquid chromatography to validate, metabolites involved in the coordination of metamorphic processes.Packaging10 mg in autosample vial
5, 25 g in poly bottleBiochem/physiol ActionsL-Citrulline, when orally administered is found to ameliorate the condition of sickle cell disease in humans. L-citrulline can be a replacement for L-arginine administration in case of defective NO synthetase. L-Citrulline supplementation is found to fulfill the purpose of NO-dependent signaling.
Intermediate in the production of nitric oxide from L-arginine by NO synthetase.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7629.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) detection: suitable color white to off-white SMILES string N[C@@H](CCCNC(N)=O)C(O)=O InChI 1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1 InChI key RHGKLRLOHDJJDR-BYPYZUCNSA-N
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L-Cystathionine
Empirical Formula (Hill Notation): C7H14N2O4S CAS Number: 56-88-2 Molecular Weight: 222.26 Beilstein/REAXYS Number: 2505200 EC Number: 200-295-8 MDL number: MFCD00036685 PubChem Substance ID: 24892965 NACRES: NA.26
Кат. номер C7505-10MG C7505-50MG C7505-250MG ApplicationL-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.Packaging10 mg in glass bottle
50, 250 mg in poly bottleBiochem/physiol ActionsL-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine. It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s). L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders. In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7505.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) UHPLC: suitable color white mp >300 °C storage temp. 20°C SMILES string N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O InChI 1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1 InChI key ILRYLPWNYFXEMH-WHFBIAKZSA-N
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L-Cysteic acid monohydrate
Empirical Formula (Hill Notation): C3H7NO5S · H2O Linear Formula: HO3SCH2CH(NH2)CO2H·H2O CAS Number: 23537-25-9 Molecular Weight: 187.17 Beilstein/REAXYS Number: 3714036 MDL number: MFCD00149544 PubChem Substance ID: 24858207 NACRES: NA.26
Кат. номер 30170-10G 30170-INTR 30170-50G ApplicationInternal standard for amino acid analysis.Biochem/physiol ActionsL-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).
L-Cysteic acid is a sulfur containing aspartate analogue that may be used as a competitive inhibitor of the bacterial aspartate:alanine antiporter (AspT) exchange of aspartate and in other aspartate biological systems. L-Cysteic acid is used in monomeric surfactant development.ПараметрыQuality Level 200, assay 99.0% (T) form powder or crystals optical activity []20/D +7.5±0.5°, c = 5% in H2O application(s) LC/MS: suitable, peptide synthesis: suitable color white to faint yellow mp 267 °C (dec.) (lit.) solubility H2O: soluble SMILES string [H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O InChI 1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1 InChI key PCPIXZZGBZWHJO-DKWTVANSSA-N
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L-Cysteine
Empirical Formula (Hill Notation): C3H7NO2S Linear Formula: HSCH2CH(NH2)CO2H CAS Number: 52-90-4 Molecular Weight: 121.16 Beilstein/REAXYS Number: 1721408 EC Number: 200-158-2 MDL number: MFCD00064306 eCl@ss: 32160406 PubChem Substance ID: 24892959 NACRES: NA.75
Кат. номер C7352-100G C7352-10MG C7352-1G-KC C7352-1KG C7352-25G C7352-1G C7352-25KG General descriptionL-Cysteine is one of the sulfur containing proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of bonds that modulate the secondary and ternary structure of proteins. L-Cysteine is an essential precursor for inorganic sulfates, coenzyme A. Cysteine is an essential and limiting for the formation of glutathione, an important antioxidant, within the cell. Mammalian liver can synthesize L-cysteine and is a semi-essential amino acid. L-cysteine prevents oxidation of nerve cells, aids in maintaining the stability and rigidity of connective tissues. L-cysteine speeds up the healing process of the body and reduces inflammatory reactions. L-cysteine protects testis partially against acrylamide induced toxicity. L-cysteine can prevent DNA damage during cryopreservation and preserves semen quality.
L-Cysteine is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. Cysteine is essential and limiting for the formation of glutathione, an important antioxidant, within the cell.ApplicationL-Cysteine has been used:- as a media supplement in Trypticase-Yeast Extract-Iron-Serum (TYI-S-33) media for the culture of Giardia lamblia, to make enzyme solution in Dulbeccos modified Eagles medium (DMEM) to establish hippocampus culture
- to test its protective effect on acrylamide induced toxicity in testis
- in the preparation of tris acetic acid extender solution for cryopreservation of semen
- as an additive to make papain digestion solution
Packaging10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsNMDA glutamatergic receptor agonist.Other NotesL-Cysteine is used to supplement cell culture media. This product is a non-animal source amino acid useful for serum-free media formulations intended for biomanufacturing applications.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7352.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.ПараметрыQuality Level 200 biological source non-animal source product line BioReagent assay 98% form crystalline powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white mp 240 °C (dec.) (lit.) solubility H2O: 25 mg/mL SMILES string N[C@@H](CS)C(O)=O InChI 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1 InChI key XUJNEKJLAYXESH-REOHCLBHSA-N
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L-Cysteine ethyl ester hydrochloride
Empirical Formula (Hill Notation): C5H11NO2S · HCl Linear Formula: HSCH2CH(NH2)COOC2H5 · HCl CAS Number: 868-59-7 Molecular Weight: 185.67 Beilstein/REAXYS Number: 3562600 EC Number: 212-779-6 MDL number: MFCD00012631 eCl@ss: 32160406 PubChem Substance ID: 24892386 NACRES: NA.22
Кат. номер C121908-100G C121908-25G ПараметрыQuality Level 200, assay 98% optical activity []20/D 7.9°, c = 1 in 1 M HCl optical purity ee: 99% (GLC) reaction suitability reaction type: solution phase peptide synthesis application(s) peptide synthesis: suitable color white mp 123-125 °C (lit.) SMILES string Cl[H].CCOC(=O)[C@@H](N)CS InChI 1S/C5H11NO2S.ClH/c1-2-8-5(7)4(6)3-9;/h4,9H,2-3,6H2,1H3;1H/t4-;/m0./s1 InChI key JFKJWWJOCJHMGV-WCCKRBBISA-N
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L-Cysteine hydrochloride
Empirical Formula (Hill Notation): C3H7NO2S · HCl Linear Formula: HSCH2CH(NH2)COOH · HCl CAS Number: 52-89-1 Molecular Weight: 157.62 Beilstein/REAXYS Number: 3560277 EC Number: 200-157-7 MDL number: MFCD00064553 PubChem Substance ID: 24892395 NACRES: NA.32
Кат. номер C1276-1G C1276-1G-KC C1276-250G C1276-10G C1276-50G C1276-100G ApplicationL-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.Biochem/physiol ActionsNMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.
Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.ПараметрыQuality Level 100, grade anhydrous assay 98% (TLC) form powder application(s) UHPLC: suitable color white mp 174.1-174.7 °C solubility H2O: 50 mg/mL, clear, colorless SMILES string Cl[H].N[C@@H](CS)C(O)=O InChI 1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1 InChI key IFQSXNOEEPCSLW-DKWTVANSSA-N Gene Information human ... AMPA 1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... AMPA 1(14799), GRIA2(14800), GRIA3(53623), GRIA4(14802), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... AMPA 1(50592), GRIA2(29627), GRIA3(29628), GRIA4(29629), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)
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L-Cysteine hydrochloride hydrate
Empirical Formula (Hill Notation): C3H7NO2S · HCl · xH2O Linear Formula: HSCH2CH(NH2)CO2H·HCl·xH2O CAS Number: 345909-32-2 Molecular Weight: 157.62 (anhydrous basis) EC Number: 200-157-7 MDL number: MFCD00065606 eCl@ss: 32160406 PubChem Substance ID: 24892385 NACRES: NA.22
Кат. номер C121800-5G C121800-100G ПараметрыQuality Level 100, assay 99% optical activity []23/D +5.2°, c = 2 in 5 M HCl reaction suitability reaction type: solution phase peptide synthesis application(s) affinity chromatography: suitable, peptide synthesis: suitable color white storage temp. 2-8°C SMILES string Cl[H].[H]O[H].N[C@@H](CS)C(O)=O InChI 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1 InChI key QIJRTFXNRTXDIP-JIZZDEOASA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 - H335 pcodes P302 + P352 - P305 + P351 + P338 Target Organs Respiratory system Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Cysteine hydrochloride monohydrate
Empirical Formula (Hill Notation): C3H7NO2S · HCl · H2O Linear Formula: HSCH2CH(NH2)COOH · HCl · H2O CAS Number: 7048-04-6 Molecular Weight: 175.63 Beilstein/REAXYS Number: 5158059 EC Number: 200-157-7 MDL number: MFCD00065606 eCl@ss: 32160406 PubChem Substance ID: 24892902 NACRES: NA.26
Кат. номер C6852-VAR C6852-100G C6852-25G C6852-1KG C6852-BR C6852-25KG ApplicationL-Cysteine hydrochloride monohydrate has been used as a component of yeast dropout media for culturing yeasts. It has also been used as a component of differential reinforced clostridial broth (DRCM) for the isolation of clostridia.Packaging25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsCysteine (Cys) is a sulfur-containing amino acid that modulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and in involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.
NMDA glutamatergic receptor antagonist.Параметрыbiological source non-animal source Quality Level 200, Agency/Method meets EP testing specifications, meets USP testing specifications assay 98.5-101.0% dry basis form powder or crystals application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white Featured Industry Pharmaceutical (small molecule) SMILES string O.Cl.N[C@@H](CS)C(O)=O InChI 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1 InChI key QIJRTFXNRTXDIP-JIZZDEOASA-N
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L-Cysteine S-sulfate
Empirical Formula (Hill Notation): C3H7NO5S2 CAS Number: 1637-71-4 Molecular Weight: 201.22 Beilstein/REAXYS Number: 1726832 MDL number: MFCD00133440 PubChem Substance ID: 24892471
Кат. номер C2196-25MG-PW C2196-5MG C2196-25MG C2196-5MG-PW Packaging5 mg in glass bottle
25 mg in poly bottleBiochem/physiol ActionsL-Cysteine S-sulfate (LCSS) is used as an NMDA glutamatergic receptor agonist. It serves as a substrate for cystine lyase(s).
Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cysteine serves as a precursor for the rate limiting step in glutathione synthesis that occurs in neurons. It donates inorganic sulfate for detoxification reactions. Therefore, L-cysteine might be associated with neuroprotection. It is found to obstruct the entry of heavy metal ions across the blood-brain barrier into the brain. Increased levels of L-cysteine might lead to neurotoxicity.Other NotesTandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C2196.pdf , Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.,ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) ligand binding assay: suitable color white storage temp. 20°C SMILES string N[C@@H](CSS(O)(=O)=O)C(O)=O InChI 1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1 InChI key NOKPBJYHPHHWAN-REOHCLBHSA-N
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L-Cystine
Empirical Formula (Hill Notation): C6H12N2O4S2 Linear Formula: [-SCH2CH(NH2)CO2H]2 CAS Number: 56-89-3 Molecular Weight: 240.30 Beilstein/REAXYS Number: 1728094 EC Number: 200-296-3 MDL number: MFCD00064228 eCl@ss: 32160406 PubChem Substance ID: 24893101 NACRES: NA.26
Кат. номер C8755-1G C8755-1G-KC C8755-500G C8755-100G C8755-1KG C8755-25G ApplicationL-Cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. It is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues.Packaging1 kg in poly bottle
100, 500 g in poly bottleBiochem/physiol ActionsCysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.Параметрыbiological source human hair Quality Level 200, assay 98% (TLC) form crystalline application(s) cell analysis: suitable, peptide synthesis: suitable color white to off-white mp >240 °C (dec.) (lit.) solubility 1 M HCl: 50 mg/mL, clear, colorless to faintly yellow storage temp. room temp SMILES string N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O InChI 1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1 InChI key LEVWYRKDKASIDU-IMJSIDKUSA-N
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L-Cystine dihydrochloride
Empirical Formula (Hill Notation): C6H12N2O4S2 · 2HCl CAS Number: 30925-07-6 Molecular Weight: 313.22 EC Number: 250-391-9 MDL number: MFCD00070399 PubChem Substance ID: 24892885 NACRES: NA.26
Кат. номер C6727-100G C6727-1KG C6727-25G C6727-25KG C6727-BR ApplicationNon-animal sourced L-cystine is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.Packaging25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsCystine is the dimeric form of cysteine. Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-Cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.CautionhygroscopicПараметрыbiological source non-animal source Quality Level 200, product line BioReagent assay 98.0% dry basis form crystalline powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white to off-white mp 211.36 °C solubility 2 M HCl: 50 mg/mL SMILES string Cl.Cl.N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O InChI 1S/C6H12N2O4S2.2ClH/c7-3(5(9)10)1-13-14-2-4(8)6(11)12;;/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12);2*1H/t3-,4-;;/m0../s1 InChI key HHGZUQPEIHGQST-RGVONZFCSA-N
Safety Informationpictograms GHS05 signalword Danger hcodes H314 pcodes P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 Personal Protective Equipment Eyeshields,, Gloves,, type N95 (US), RIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Ethionine
Empirical Formula (Hill Notation): C6H13NO2S Linear Formula: C2H5SCH2CH2CH(NH2)CO2H CAS Number: 13073-35-3 Molecular Weight: 163.24 EC Number: 235-966-4 MDL number: MFCD00002626 PubChem Substance ID: 24894397
Кат. номер E1260-250MG E1260-1G E1260-5G Packaging250 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsAn analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.ПараметрыQuality Level 100, assay 99% (TLC) form powder color white mp 280 °C (dec.) (lit.) storage temp. 20°C SMILES string CCSCC[C@H](N)C(O)=O InChI 1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 InChI key GGLZPLKKBSSKCX-YFKPBYRVSA-N
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 - H335 pcodes P302 + P352 - P305 + P351 + P338 Target Organs Respiratory system Personal Protective Equipment dust mask type N95 (US),, Eyeshields,, Gloves, RIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
L-Fmoc--(6-chloro-4-pyridinyl)alanine ALD00402-250MG
Empirical Formula (Hill Notation): C23H19ClN2O4 Molecular Weight: 422.86 PubChem Substance ID: 329772666 ApplicationPhenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H ActivationPackaging250 mg in amber glass bottleOther NotesLigand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral a–Amino Acids,ПараметрыQuality Level 100, form solid reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable functional group Fmoc storage temp. 2-8°C SMILES string O=C(O)[C@H](CC1=CC=NC(Cl)=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O InChI 1S/C23H19ClN2O4/c24-21-12-14(9-10-25-21)11-20(22(27)28)26-23(29)30-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-10,12,19-20H,11,13H2,(H,26,29)(H,27,28)/t20-/m0/s1 InChI key QIUBOGQEEPYLOR-FQEVSTJZSA-N
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L-Fmoc-3-fluorophenylalanine ALD00374-250MG
Empirical Formula (Hill Notation): C24H20FNO4 CAS Number: 198560-68-8 Molecular Weight: 405.42 MDL number: MFCD00672328 PubChem Substance ID: 329772658 ApplicationPhenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation.Packaging250 mg in amber glass bottleOther NotesLigand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral –Amino Acids,ПараметрыQuality Level 100, form solid reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable color beige functional group Fmoc storage temp. 2-8°C SMILES string FC1=CC=CC(C[C@H](NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)C(O)=O)=C1 InChI 1S/C24H20FNO4/c25-16-7-5-6-15(12-16)13-22(23(27)28)26-24(29)30-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1 InChI key DWSDVARCJDOADL-QFIPXVFZSA-N
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L-Fmoc-4-fluorophenylalanine 798215-250MG
Empirical Formula (Hill Notation): C24H20FNO4 CAS Number: 169243-86-1 Molecular Weight: 405.42 Beilstein/REAXYS Number: 8287377 MDL number: MFCD00191197 PubChem Substance ID: 329768632 ApplicationPhenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation.Packaging250 mg in amber glass bottleOther NotesLigand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral –Amino
Acids,ПараметрыQuality Level 100, form solid reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable color white functional group Fmoc storage temp. 2-8°C SMILES string OC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24 InChI 1S/C24H20FNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1 InChI key IXUMACXMEZBPJG-QFIPXVFZSA-N
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L-Fmoc-4-trifluoromethylphenylalanine ALD00380-250MG
Empirical Formula (Hill Notation): C25H20F3NO4 CAS Number: 247113-86-6 Molecular Weight: 455.43 MDL number: MFCD00797581 PubChem Substance ID: 329772661 NACRES: NA.26 ApplicationPhenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation.Packaging250 mg in amber glass bottleOther NotesLigand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral –Amino Acids,ПараметрыQuality Level 100, form solid reaction suitability reaction type: Fmoc solid-phase peptide synthesis application(s) peptide synthesis: suitable color beige functional group Fmoc storage temp. 2-8°C SMILES string O=C(O)[C@@H](NC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O)CC4=CC=C(C(F)(F)F)C=C4 InChI 1S/C25H20F3NO4/c26-25(27,28)16-11-9-15(10-12-16)13-22(23(30)31)29-24(32)33-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,29,32)(H,30,31)/t22-/m0/s1 InChI key YMEGJWTUWMVZPD-QFIPXVFZSA-N
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L-Glutamic acid
Empirical Formula (Hill Notation): C5H9NO4 Linear Formula: HO2CCH2CH2CH(NH2)CO2H CAS Number: 56-86-0 Molecular Weight: 147.13 Beilstein/REAXYS Number: 1723801 EC Number: 200-293-7 MDL number: MFCD00002634 eCl@ss: 32160406 PubChem Substance ID: 24895052 NACRES: NA.26
Кат. номер G1251-10MG-KC G1251-100G G1251-1G-KC G1251-5KG G1251-1G G1251-1KG G1251-500G G1251-BR ApplicationL-Glutamic acid has been used to enhance endogenous acetylcholine overflow. It has been used as a supplement in the growth medium of meat-Spoiling Pseudomonas fragi 72.Packaging1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drumBiochem/physiol ActionsAn excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
Glutamic acid, or glutamate, the salt form of glutamic acid, functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as -aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways, that controls growth, reproduction, maintenance and immunity. It is converted to -ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle, and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase.
Glutamine serves as a source of energy for rapidly dividing cells comprising lymphocytes, enterocytes, macrophages and tumors. Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signaling. It is also known to be associated with the inhibition of apoptosis.Legal InformationReagentPlus is a registered trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 product line ReagentPlus® assay 99% (HPLC) form powder application(s) microbiological culture: suitable color white to off-white mp 205 °C (dec.) (lit.) solubility 1 M HCl: soluble 100 mg/mL density 1.54 g/cm3 at 20 °C cation traces C: 40.4-41.2%, N: 9.2-9.8% SMILES string N[C@@H](CCC(O)=O)C(O)=O InChI 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 InChI key WHUUTDBJXJRKMK-VKHMYHEASA-N Gene Information human ... CCR2(1231), GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK2(2898), GRIK3(2899), GRIK5(2901), GRIN2B(2904), GRM2(2912), SLC1A1(6505), SLC1A2(6506)
rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grm1(24414), Grm2(24415), Grm3(24416), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672), Slc1a2(29482)
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L-Glutamic acid -(7-amido-4-methylcoumarin)
Empirical Formula (Hill Notation): C15H16N2O5 CAS Number: 72669-53-5 Molecular Weight: 304.30 MDL number: MFCD00038085 PubChem Substance ID: 24895148 NACRES: NA.26
Кат. номер G7261-100MG G7261-25MG G7261-5MG G7261-1MG Packaging100 mg in glass bottleBiochem/physiol ActionsL-Glutamic acid γ-(7-amido-4-methylcoumarin) (gammaGlu-AMC) may be useful as a fluorogenic substrate for the detection, differentiation or characterization of gamma-glutamyltransferase(s)/transpeptidase(s).ПараметрыQuality Level 200, assay 98% (TLC) form powder application(s) HPLC: suitable color white to light yellow storage temp. 20°C SMILES string CC1=CC(=O)Oc2cc(NC(=O)CCC(N)C(O)=O)ccc12 InChI 1S/C15H16N2O5/c1-8-6-14(19)22-12-7-9(2-3-10(8)12)17-13(18)5-4-11(16)15(20)21/h2-3,6-7,11H,4-5,16H2,1H3,(H,17,18)(H,20,21) InChI key JPOAPPISZAGCAO-UHFFFAOYSA-N
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L-Glutamic acid -monohydroxamate
Empirical Formula (Hill Notation): C5H10N2O4 CAS Number: 1955-67-5 Molecular Weight: 162.14 MDL number: MFCD00057719 PubChem Substance ID: 24895091 NACRES: NA.26
Кат. номер G2253-1G G2253-500MG G2253-250MG G2253-100MG ApplicationL-Glutamic acid γ-monohydroxamate has been used as a standard to calculate transglutaminase (TGase) activity.Packaging100, 250, 500 mg in poly bottle
1 g in poly bottleBiochem/physiol ActionsL-Glutamic acid -monohydroxamate [L-Glu(gamma)HXM] is used as a vanadium ligand which potentiates vanadiums metabolic activity. L-Glu(gamma)HXM is also used as a substrate for E. coli asparagine synthetase B and as an ATP-dependent irreversible inhibitor of Escherichia coli gamma-glutamylcysteine synthetase.ПараметрыQuality Level 200, assay 97% (TLC) form powder application(s) detection: suitable color white to off-white storage temp. 20°C SMILES string NC(CCC(=O)NO)C(O)=O InChI 1S/C5H10N2O4/c6-3(5(9)10)1-2-4(8)7-11/h3,11H,1-2,6H2,(H,7,8)(H,9,10) InChI key YVGZXTQJQNXIAU-UHFFFAOYSA-N
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L-Glutamic acid di-tert-butyl ester hydrochloride
Empirical Formula (Hill Notation): C13H25NO4 · HCl CAS Number: 32677-01-3 Molecular Weight: 295.80 Beilstein/REAXYS Number: 3573738 MDL number: MFCD00058003 PubChem Substance ID: 24895307 NACRES: NA.26
Кат. номер G7501-5G G7501-1G G7501-250MG Biochem/physiol ActionsGlutamic acid di-tert butyl ester (GTBE) possesses convulsant properties in mice and rats. It might have unique pharmacological features that set it apart from other convulsant medications.
L-Glutamic acid di-tert-butyl ester is C-terminal and R-chain blocked derivative of L-glutamate that may be useful in the synthesis of substance P antagonistic peptides.Параметрыassay 98% Quality Level 200, form powder color white storage temp. 20°C SMILES string Cl[H].[H][C@](N)(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C InChI 1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1 InChI key LFEYMWCCUAOUKZ-FVGYRXGTSA-N
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L-Glutamic acid monosodium salt hydrate
Empirical Formula (Hill Notation): C5H8NNaO4 · xH2O CAS Number: 142-47-2 Molecular Weight: 169.11 (anhydrous basis) EC Number: 205-538-1 MDL number: MFCD00013074 PubChem Substance ID: 24895237 NACRES: NA.75
Кат. номер G5889-100G G5889-1KG G5889-500G General descriptionL-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.ApplicationL-Glutamic acid monosodium salt hydrate has been used:- to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
- as a component in YNG (yeast nitrogen base glutamate) medium
- used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
- as a component of fresh media to culture neurons and to assess glutamate uptake
Packaging1 kg in poly bottle
100, 500 g in poly bottleBiochem/physiol ActionsMonosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.ПараметрыQuality Level 200, product line BioReagent assay 99% form powder application(s) cell culture | insect: suitable, cell culture | mammalian: suitable color white to off-white mp 163 °C InChI 1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2; InChI key JYDGDQPVBSBYRT-UHFFFAOYSA-N
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L-Glutamic acid potassium salt monohydrate
Empirical Formula (Hill Notation): C5H8KNO4 · H2O CAS Number: 6382-01-0 Molecular Weight: 203.23 Beilstein/REAXYS Number: 3637377 MDL number: MFCD00150343 PubChem Substance ID: 24895045
Кат. номер G1149-500G G1149-1KG G1149-100G General descriptionL-Glutamic acid, an amino acid is mainly found in various food products in its free form. It is ubiquitously present in the brain of mammals.ApplicationL-Glutamic acid potassium salt monohydrate has been used as a component in KG buffer for cardiomyocyte isolation and culture.Packaging100, 500 g in poly bottleBiochem/physiol ActionsL-Glutamic acid plays a major role in several metabolic pathways. It acts as excitatory neurotransmitter in the cerebral cortex. An plays a key role in learning, memory and brain aging processes. It is involved in neuronal differentiation, migration and survival in the developing brain. High levels of glutamic acid is observed in Alzheimers, Parkinsons diseases and epilepsy.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.ПараметрыQuality Level 200, product line BioReagent assay 99% (HPLC) form powder application(s) cell culture | insect: suitable color white SMILES string O.[K+].N[C@@H](CCC([O-])=O)C(O)=O InChI 1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1 InChI key XIBUKSQTWSKJMQ-QTNFYWBSSA-M
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L-Glutamine
Empirical Formula (Hill Notation): C5H10N2O3 Linear Formula: H2NCOCH2CH2CH(NH2)CO2H CAS Number: 56-85-9 Molecular Weight: 146.14 Beilstein/REAXYS Number: 1723797 EC Number: 200-292-1 MDL number: MFCD00008044 eCl@ss: 32160406 PubChem Substance ID: 24895342 NACRES: NA.26
Кат. номер G8540-1KG G8540-25G G8540-100G G8540-10MG G8540-BR G8540-25KG ApplicationL-Glutamine has been used as one of the components for the preparation of calcium-free mCZB medium. It has also been used as a supplement in a culture medium for rat hippocampal slices.Packaging10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottleBiochem/physiol ActionsGlutamine provides the necessary nitrogen, carbon and the reducing equivalents required for cell growth and division during cell culture. L-Glutamic acid aids the incorporation of NH4+ into biomolecules.
L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.ПараметрыQuality Level 200 biological source non-animal source Agency/Method meets USP testing specifications assay 99.0-101.0% form powder application(s) cell culture | mammalian: suitable impurities endotoxin, tested color white mp 185 °C (dec.) (lit.) solubility H2O: 25 mg/mL Featured Industry Agriculture SMILES string N[C@@H](CCC(N)=O)C(O)=O InChI 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1 InChI key ZDXPYRJPNDTMRX-VKHMYHEASA-N Gene Information rat ... Ggt1(116568)
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L-Glutamine solution G2150-20ML
CAS Number: 56-85-9 MDL number: MFCD00008044 eCl@ss: 32160406 PubChem Substance ID: 24895088 NACRES: NA.75 Biochem/physiol ActionsL-glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.Preparation NotePrepared in cell culture grade water.Legal InformationHybri-Max is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 400, grade Hybri-Max™ sterility sterile-filtered assay 99% (TLC) form solution application(s) cell culture | hybridoma: suitable impurities endotoxin, tested color clear colorless shipped in dry ice storage temp. 20°C SMILES string N[C@@H](CCC(N)=O)C(O)=O InChI 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1 InChI key ZDXPYRJPNDTMRX-VKHMYHEASA-N Gene Information rat ... Ggt1(116568)
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L-Glutamine solution
CAS Number: 56-85-9 EC Number: 200-292-1 MDL number: MFCD00008044 PubChem Substance ID: 24895310 NACRES: NA.75
Кат. номер G7513-6X100ML G7513-20ML G7513-100ML G7513-1L G7513-450ML G7513-500ML G7513-PH ApplicationL-glutamine is an essential amino acid that is a crucial component of culture media, which serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.Biochem/physiol ActionsL-glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.Preparation NotePrepared in cell culture grade water.ПараметрыQuality Level 400 sterility sterile-filtered product line BioXtra form solution concentration 200 mM application(s) cell culture | mammalian: suitable impurities endotoxin, tested shipped in dry ice storage temp. 20°C SMILES string N[C@@H](CCC(N)=O)C(O)=O InChI 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1 InChI key ZDXPYRJPNDTMRX-VKHMYHEASA-N Gene Information rat ... Ggt1(116568)
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L-Glutamine t-butyl ester hydrochloride
Empirical Formula (Hill Notation): C9H18N2O3 · HCl CAS Number: 39741-62-3 Molecular Weight: 238.71 MDL number: MFCD00039081 PubChem Substance ID: 24895370 NACRES: NA.26
Кат. номер G9375-1G G9375-5G G9375-250MG ApplicationL-Glutamine t-butyl ester a C-terminally blocked α amino acid that may be useful in studies of glutamine transport.Параметрыassay 98% Quality Level 200, form crystalline application(s) cell analysis: suitable color white storage temp. 20°C SMILES string Cl.CC(C)(C)OC(=O)C(N)CCC(N)=O InChI 1S/C9H18N2O3.ClH/c1-9(2,3)14-8(13)6(10)4-5-7(11)12;/h6H,4-5,10H2,1-3H3,(H2,11,12);1H InChI key ZEPNUNKDKQACNC-UHFFFAOYSA-N
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L-Glutathione oxidized
Empirical Formula (Hill Notation): C20H32N6O12S2 CAS Number: 27025-41-8 Molecular Weight: 612.63 Beilstein/REAXYS Number: 1718700 EC Number: 248-170-7 MDL number: MFCD00063106 PubChem Substance ID: 24895174 NACRES: NA.26
Кат. номер G4501-1G G4501-250MG G4501-500MG G4501-100MG G4501-5G Amino Acid SequenceGlu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]Packaging1, 5 g in poly bottle
100, 250, 500 mg in poly bottleBiochem/physiol ActionsL-Glutathione, oxidized is frequently measure in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.ПараметрыQuality Level 200, assay 98% form lyophilized powder application(s) detection: suitable impurities Ethanol, free color white solubility H2O: 50 mg/mL, clear, colorless storage temp. 2-8°C SMILES string N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O InChI 1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1 InChI key YPZRWBKMTBYPTK-BJDJZHNGSA-N
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L-Glutathione oxidized disodium salt
Empirical Formula (Hill Notation): C20H30N6Na2O12S2 CAS Number: 103239-24-3 Molecular Weight: 656.59 Beilstein/REAXYS Number: 6265389 MDL number: MFCD00148894 PubChem Substance ID: 24895179 NACRES: NA.26
Кат. номер G4626-5G G4626-1G G4626-100MG G4626-CP G4626-500MG 2530126 G4626-EW G4626-250MG Amino Acid Sequence(-Glu-Cys-Gly) (-Glu-Cys-Gly) [Disulfide bridge: 2a-2b]ApplicationL-Glutathione oxidized disodium salt has been used in 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB)/glutathione reductase enzyme recycling method to determine plasma or tissue glutathione levels. It has also been used in NADPH-dependent glutathione disulfide reduction assay.Packaging1, 5 g in poly bottle
100, 250, 500 mg in poly bottleBiochem/physiol ActionsOxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.ПараметрыQuality Level 200, assay 98% form powder application(s) HPLC: suitable impurities ethanol, essentially free color white to off-white storage temp. 20°C SMILES string [Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O InChI 1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1 InChI key DRFILBXQKYDTFW-JIWRMXRASA-L
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L-Glutathione reduced
Empirical Formula (Hill Notation): C10H17N3O6S Linear Formula: H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H CAS Number: 70-18-8 Molecular Weight: 307.32 Beilstein/REAXYS Number: 1729812 EC Number: 200-725-4 MDL number: MFCD00065939 PubChem Substance ID: 24895164 NACRES: NA.26
Кат. номер G4251-10G G4251-10MG G4251-5G G4251-VAR G4251-EW G4251-PM G4251-100G G4251-300MG G4251-1G G4251-250G G4251-25G G4251-500G G4251-50G G4251-BR G4251-10KG G4251-1EA Amino Acid Sequenceγ-Glu-Cys-GlyApplicationL-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads. It has been used to prepare a standard curve for GSH analyses.
May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.Packaging10 mg in glass bottle
300 mg in poly bottle
1, 5, 10, 25, 50, 100, 250, 500 g in poly bottleBiochem/physiol ActionsEndogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Reduced L-glutathione (GSH) is a thiol compound and is associated with catabolism and transportation. Plasma GSH levels are associated with Parkinson′s diseases, Alzheimer′s, diabetes, macular degeneration, and HIV (human immunodeficiency virus) disease.ПараметрыQuality Level 300 assay 98.0% form powder application(s) detection: suitable color white mp 192-195 °C (dec.) (lit.) storage temp. 2-8°C SMILES string N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O InChI 1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 InChI key RWSXRVCMGQZWBV-WDSKDSINSA-N
Safety InformationPersonal Protective Equipment Eyeshields, Gloves, type N95 (US) RIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point(F) Not applicable Flash Point(C) Not applicable Узнать цену -
L-Histidine
Empirical Formula (Hill Notation): C6H9N3O2 CAS Number: 71-00-1 Molecular Weight: 155.15 Beilstein/REAXYS Number: 84088 EC Number: 200-745-3 MDL number: MFCD00064315 eCl@ss: 32160406 PubChem Substance ID: 24895816 NACRES: NA.26
Кат. номер H8000-VAR H8000-100G H8000-10G H8000-5KG H8000-25G H8000-500G H8000-5G H8000-1KG ApplicationL-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.Packaging5, 10, 25, 100, 500 g in poly bottle
1 kg in poly bottle
5 kg in poly drumBiochem/physiol ActionsL-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Precursor of histamine by action of histidine decarboxylase.Legal InformationReagentPlus is a registered trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 product line ReagentPlus® assay 99% (TLC) form powder application(s) cell analysis: suitable color white to off-white mp 282 °C (dec.) (lit.) solubility 0.5 M HCl: 50 mg/mL SMILES string N[C@@H](Cc1c[nH]cn1)C(O)=O InChI 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1 InChI key HNDVDQJCIGZPNO-YFKPBYRVSA-N Gene Information human ... CA1(759), CA2(760)
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L-Histidine -naphthylamide
Empirical Formula (Hill Notation): C16H16N4O CAS Number: 7424-15-9 Molecular Weight: 280.32 EC Number: 231-052-4 MDL number: MFCD00051166 PubChem Substance ID: 24895761 NACRES: NA.26
Кат. номер H6759-250MG H6759-100MG H6759-25MG Packaging250 mg in glass bottleBiochem/physiol ActionsL-Histidine β-naphthylamide is an analogue of L-histidine used to study structural roles of L-histidine in functions such as the activation of HutP protein transcription. L-Histidine β-naphthylamide may also be used to study the specificity and kinetics of various proteases and peptidases.Параметрыassay 98% (TLC) Quality Level 200, form powder color white to faint yellow storage temp. 20°C SMILES string N[C@@H](Cc1cnc[nH]1)C(=O)Nc2ccc3ccccc3c2 InChI 1S/C16H16N4O/c17-15(8-14-9-18-10-19-14)16(21)20-13-6-5-11-3-1-2-4-12(11)7-13/h1-7,9-10,15H,8,17H2,(H,18,19)(H,20,21)/t15-/m0/s1 InChI key DKDILZBBFKZMRO-HNNXBMFYSA-N
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L-Histidine dihydrochloride
Empirical Formula (Hill Notation): C6H9N3O2 · 2HCl CAS Number: 6027-02-7 Molecular Weight: 228.08 Beilstein/REAXYS Number: 6119230 EC Number: 227-890-5 MDL number: MFCD00066569 PubChem Substance ID: 57651406 NACRES: NA.26
Кат. номер 53340-50G 53340-10G Biochem/physiol ActionsL-Histidine is a positively charged imidazole-side chain containing amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.
L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.ПараметрыQuality Level 100, assay 99.0% (AT) form powder or crystals optical activity []20/D +6.5±1°, c = 8% in H2O ign. residue 0.1% (as SO4) color white mp 240-245 °C (dec.) solubility H2O: soluble, saline: soluble anion traces sulfate (SO42-): 50 mg/kg cation traces As: 0.1 mg/kg, Cd: 5 mg/kg, Co: 5 mg/kg, Cu: 5 mg/kg, Fe: 5 mg/kg, NH4+: 500 mg/kg, Ni: 5 mg/kg, Pb: 5 mg/kg, Zn: 5 mg/kg SMILES string Cl.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O InChI 1S/C6H9N3O2.2ClH/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);2*1H/t5-;;/m0../s1 InChI key XEJCDBUNISUVGZ-XRIGFGBMSA-N
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