-Nicotinamide adenine dinucleotide 2-phosphate reduced tetrasodium salt hydrate
Empirical Formula (Hill Notation): | C21H26N7Na4O17P3 · xH2O |
CAS Number: | 2646-71-1 |
Molecular Weight: | 833.35 (anhydrous basis) |
EC Number: | 220-163-3 |
MDL number: | MFCD00036263 |
PubChem Substance ID: | 24278049 |
NACRES: | NA.51 |
Кат. номер |
N7505-100MG |
N7505-1G |
N7505-500MG |
N7505-25MG |
N7505-250MG |
25, 100, 250, 500 mg in poly bottle
1 g in poly bottle
NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
-Nicotinamide adenine dinucleotide 2-phosphate (NADP+) and -Nicotinamide adenine dinucleotide 2-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated
in vivio by the pentose phosphate pathway (PPP).
This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Chemically reduced
Packaged based on solid weight.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Quality Level | 300 |
assay | ≥97% (HPLC), ≥97% (spectrophotometric assay) |
solubility | 10 mM NaOH: soluble 50 mg/mL, clear |
storage temp. | −20°C |
SMILES string | [Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O |
InChI | 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1 |
InChI key | WYWWVJHQDVCHKF-MPUNMZHWSA-J |
Personal Protective Equipment | Eyeshields, Gloves, type N95 (US) |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |