Biochemicals
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12:0(2R-OH) Ceramide 860811P-5MG
Empirical Formula (Hill Notation): C30H59NO4 CAS Number: 1246298-44-1 Molecular Weight: 497.79 NACRES: NA.25 General descriptionCeramides containing 2-hydroxy fatty acid (hFA) are found primarily in the epidermis. 12:0(2R-OH) Ceramide is a 2R hydroxylated lauric acid-containing ceramide.Biochem/physiol ActionsHydroxy fatty acid (hFA)-sphingolipids play a specific role in cell signaling. Synthesis of hFA-ceramides requires fatty acid 2-hydroxylase (FA2H). Mutations of this key enzyme are associated with the development of nervous system disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for the epidermal permeability barrier function. The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.Packaging5 mL Amber Glass Screw Cap Vial (860811P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860811P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0(2S-OH) Ceramide 860812P-5MG
Empirical Formula (Hill Notation): C30H59NO4 CAS Number: 1246298-45-2 Molecular Weight: 497.79 NACRES: NA.25 General descriptionCeramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis. 12:0(2S-OH) Ceramide is a 2S hydroxylated lauric acid-containing ceramide.Biochem/physiol ActionsHydroxy fatty acid (hFA)-sphingolipids facilitate cell signaling. hFA-ceramides contribute to the permeability barrier function of the epidermis. Synthesis of hFA-ceramides are catalyzed by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. An antitumor drug, PM02734 requires hFA-ceramides in the cell membrane to exhibit its activity.Packaging5 mL Amber Glass Screw Cap Vial (860812P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860812P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0-13:0 PC LM1000-1EA
Empirical Formula (Hill Notation): C33H66NO8P CAS Number: 1246304-45-9 Molecular Weight: 635.85 NACRES: NA.25 General descriptionPhospholipids are major structural biomolecules found in biological membranes. Phosphocholine (PC) is an intermediate of phosphatidylcholine synthesis catalyzed by choline kinase.Application12:0-13:0 PC or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine has been used:- as an internal standard in liquid chromatography/mass spectrometry (LC/MS) analysis
- as a lipid standard for phospholipid quantification by MS
- as an internal standard for the retention time recalibration during LC-MS data processing
- as an MS grade lipid standard for lipid extraction from macrophages
Biochem/physiol ActionsPhospholipids participate in protein mediated intracellular and extracellular signaling processes.Packaging2 mL Amber Glass Sealed Ampule (LM1000-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1000-1EA) Торговая марка Avanti Polar Lipids LM1000 concentration ~10 µg/mL (Refer to C of A for lot specific concentration.) shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Узнать цену -
12:0-13:0 PE LM1100-1EA
Empirical Formula (Hill Notation): C30H60NO8P CAS Number: 1246304-47-1 Molecular Weight: 593.77 NACRES: NA.25 General descriptionPhosphatidylethanolamine is the second most abundant phospholipid, essential for various cellular processes. It is a non-bilayer forming phospholipid.Application12:0-13:0 PE has been used to study the lipid′s interaction with the membrane protein of interest and as a quantitative lipid standard to monitor various lipid extracts concentration.Biochem/physiol ActionsPhosphatidylethanolamine (PE) plays a vital role in oxidative phosphorylation, mitochondrion stability and membrane fusion. It functions as a chaperone by aiding in folding certain membrane proteins. PE contributes to the process of autophagy.Packaging2 mL Amber Glass Sealed Ampule (LM1100-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1100-1EA) Торговая марка Avanti Polar Lipids LM1100 concentration ~10 µg/mL (Refer to C of A for lot specific concentration.) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
12:0-13:0 PG LM1200-1EA
Empirical Formula (Hill Notation): C31H64NO10P CAS Number: 1246304-49-3 Molecular Weight: 641.81 NACRES: NA.25 General descriptionPhosphatidylglycerol (PG), an anionic phospholipid is a predominant component of the cell membrane. It is localized in the thylakoid membrane of chloroplast in plants. PG is synthesized by phosphatidic acid in E. coli.Application12:0-13:0 PG has been used to study the lipid′s interaction with the membrane protein of interest.Biochem/physiol ActionsPhosphatidylglycerol contributes to photosynthetic activity by maintaining the structural photosynthetic apparatus. It is useful for the biosynthesis of cardiolipin.Packaging2 mL Amber Glass Sealed Ampule (LM1200-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1200-1EA) Торговая марка Avanti Polar Lipids LM1200 concentration ~10 µg/mL (Refer to C of A for lot specific concentration.) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
12:0-13:0 PI LM1500-1EA
Empirical Formula (Hill Notation): C34H68NO13P CAS Number: 1246304-58-4 Molecular Weight: 729.88 NACRES: NA.25 General descriptionPhosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol.Application12:0-13:0 PI or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phospho-(1-myo-inositol) has been used as an internal standard for lipid quantification/analysis using electrospray ionization tandem mass spectrometry (ESI-MS/MS) and liquid chromatography mass spectrometry (LC-MS).Packaging2 mL Amber Glass Sealed Ampule (LM1500-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1500-1EA) Торговая марка Avanti Polar Lipids LM1500 concentration ~10 µg/mL (Refer to C of A for lot specific concentration. ) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
12:0-13:0 PS LM1300-1EA
Empirical Formula (Hill Notation): C31H63N2O10P CAS Number: 1246304-52-8 Molecular Weight: 654.81 NACRES: NA.25 General descriptionPhosphatidylserine is the major anionic phospholipid in human plasma and intracellular membranes identified first in brain. It is a structural component of endoplasmic reticulum, nuclear envelopes, Golgi apparatus, inner layer of plasma membranes and outer mitochondrial membranes. PS is essential for healthy nerve cell membranes and myelin.Application12:0-13:0 PS has been used as a quantitative lipid standard to monitor different lipid extracts concentration.Biochem/physiol ActionsPhosphatidylserine plays a key role in apoptosis by regulating cell signalling molecules and in monitoring membrane fluidity. Phosphatidylserine mediates the activation of enzymes and structural components.Packaging2 mL Amber Glass Sealed Ampule (LM1300-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1300-1EA) Торговая марка Avanti Polar Lipids LM1300 concentration ~10 µg/mL (Refer to C of A for lot specific concentration.) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OC[C@](C(O)=O)([H])N)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
13(S)HODE
Empirical Formula (Hill Notation): C18H32O3 Molecular Weight: 296.44
Кат. номер 900130E-500UG 900130E-1MG General description13-S-hydroxyoctadecadienoic acid (13(S)HODE) is a metabolite of 15-lipoxygenase (15-LOX). It is an endogenous ligand of peroxisome proliferator-activated receptor (PPAR).Biochem/physiol Actions13-S-hydroxyoctadecadienoic acid (13(S)HODE) inhibits cell proliferation and induces apoptosis in many human cancers. It also enhances the activity of nuclear factor light chain enhancer of activated B cells (NF-B) in keratinocytes.Packaging2ml Amber Glass Sealed AmpuleПараметрыform ethanol solution packaging pkg of 1 x 1 mg (900130E-1mg), pkg of 1 x 500 µg (900130E-500ug) Торговая марка Avanti Polar Lipids (900130E) concentration 1 mg/mL (900130E-1MG), 500 µg/mL (900130E-500UG) application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 70°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P233 - P280 - P303 + P361 + P353 - P337 + P313 - P370 + P378 WGK Germany WGK 1 Flash Point F 55.4 °F Flash Point C 13 °C Узнать цену -
13(S)HODE Ethanolamide
Empirical Formula (Hill Notation): C20H37NO3 Molecular Weight: 339.51
Кат. номер 900131E-500UG 900131E-1MG Packaging2ml Amber Glass Sealed AmpuleПараметрыform ethanol solution packaging pkg of 1 x 1 mg (900131E-1mg), pkg of 1 x 500 µg (900131E-500ug) Торговая марка Avanti Polar Lipids (900131E) concentration 1 mg/mL (900131E-1MG), 500 µg/mL (900131E-500UG) application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 70°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P233 - P280 - P303 + P361 + P353 - P337 + P313 - P370 + P378 WGK Germany WGK 1 Flash Point F 55.4 °F Flash Point C 13 °C Узнать цену -
13:0 Coenzyme A 870713P-5MG
Empirical Formula (Hill Notation): C34H69N10O17P3S CAS Number: 1246304-38-0 Molecular Weight: 1014.95 NACRES: NA.25 General description13:0 Coenzyme A, also known as tridecanoyl Coenzyme A, is a coenzyme A derivative of tridecanoic acid. 13:0 Coenzyme A is a long-chain acyl CoA.Application13:0 Coenzyme A has been used as a spiking standard for mass spectrometry measurements of fatty acid-CoA assay products.Packaging5 mL Amber Glass Screw Cap Vial (870713P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (870713P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
13:0 Diether PC 999988P-10MG
Empirical Formula (Hill Notation): C34H72NO6P CAS Number: 328250-31-3 Molecular Weight: 621.91 NACRES: NA.25 General description13:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two tridecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.Application13:0 Diether PC or 1,2-di-O-tridecyl-sn-glycero-3-phosphocholine is suitable for bicelle preparation and as an internal standard for lipid identification in tissue.Biochem/physiol Actions13:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.Packaging5 mL Amber Glass Screw Cap Vial (999988P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (999988P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCC)COCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
13:0 Diether PC 999988C-10MG
Empirical Formula (Hill Notation): C34H72NO6P CAS Number: 328250-31-3 Molecular Weight: 621.91 NACRES: NA.25 General description13:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two tridecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.Application13:0 Diether PC or 1,2-di-O-tridecyl-sn-glycero-3-phosphocholine is suitable for bicelle preparation and as an internal standard for lipid identification in tissue.Biochem/physiol Actions13:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.Packaging5 mL Clear Glass Sealed Ampule (999988C-10mg)Параметрыpackaging pkg of 1 x 1 mL (999988C-10mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (999988C-10mg) shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCC)COCCCCCCCCCCCCC)=O
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
13:0 Lyso LPC LM1600-1EA
Empirical Formula (Hill Notation): C21H44NO7P CAS Number: 20559-17-5 Molecular Weight: 453.55 NACRES: NA.25 General descriptionLysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.Application13:0 Lyso LPC or 1-tridecanoyl-sn-glycero-3-phosphocholine has been used as an internal standard in:- lipid extraction from brain tissues
- lipid extraction from macrophages using modified Bligh and Dyer protocol
- liquid chromatography/MS analyses of lysophospholipids
Biochem/physiol ActionsLysophosphatidylcholine (LPC) is known to be a bioactive molecule, associated with the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is involved in various biological processes such as vascular reproduction, development and myelination. It is also known to be implicated in neuronal diseases and cancer.Packaging2 mL Amber Glass Sealed Ampule (LM1600-1EA)Параметрыform methanol solution packaging pkg of 1 x 1 mL (LM1600-1EA) Торговая марка Avanti Polar Lipids LM1600 concentration ~10 µg/mL (Refer to C of A for lot specific concentration. ) shipped in dry ice storage temp. 20°C SMILES string O[C@](COP(O)(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCC)=O
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 Target Organs Eyes RIDADR UN1230 - class 3 - PG 2 - Methanol, solution WGK Germany WGK 2 Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
13:0 Lyso PC 855476C-25MG
Empirical Formula (Hill Notation): C21H44NO7P CAS Number: 20559-17-5 Molecular Weight: 453.55 NACRES: NA.25 Application13:0 Lyso PC has been used as a phospholipid standard to quantify lyso-phosphatidylcholine in lipid profiling of plant polar glycerol lipids using electrospray ionization tandem mass spectrometry (ESI-MS/MS) and data processing. It may also be used as a standard in metabolomics analyses to investigate the metabolic fingerprint of childhood obesity and insulin resistance.Packaging5 mL Clear Glass Sealed Ampule (855476C-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) packaging pkg of 1 x 2.5 mL (855476C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (855476C-25mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
13:0 Lyso PC 855476P-25MG
Empirical Formula (Hill Notation): C21H44NO7P CAS Number: 20559-17-5 Molecular Weight: 453.55 NACRES: NA.25 Application13:0 Lyso PC has been used:- as an internal standard: for the quantification of targeted infant metabolites
- used as an internal standard in liquid chromatography-mass spectrometry (LC-MS) to identify changes in lipid profile of eggs
- as an internal standard for tandem mass spectrometry analysis of lipid species
Packaging5 mL Amber Glass Screw Cap Vial (855476P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855476P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
13:0 Lyso PE 856706P-5MG
Empirical Formula (Hill Notation): C18H38NO7P CAS Number: 1223068-83-4 Molecular Weight: 411.47 NACRES: NA.25 Application13:0 Lyso PE has been used as an internal standard for the quantification of glycerophospholipids.Packaging5 mL Amber Glass Screw Cap Vial (856706P-5mg)Параметрыassay >99% (may contain up to 10% of the 2-LPE isomer, TLC) form powder packaging pkg of 1 x 5 mg (856706P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
13:0 Lyso PG 858126C-5MG
Empirical Formula (Hill Notation): C19H38NaO9P CAS Number: 1246298-10-1 Molecular Weight: 464.46 NACRES: NA.25 Packaging5 mL Clear Glass Sealed Ampule (858126C-5mg)Параметрыassay >99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC) packaging pkg of 1 x 1 mL (858126C-5mg) Торговая марка Avanti Polar Lipids concentration 5 mg/mL (858126C-5mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
13:0 Lyso PI
Empirical Formula (Hill Notation): C22H46NO12P CAS Number: 1246430-02-3 Molecular Weight: 547.57 NACRES: NA.25
Кат. номер 850101P-500UG 850101P-100UG General descriptionLysophosphatidylinositol (LPI), produced by phospholipase A2 is a bioactive lipid.Application13:0 Lyso PI (1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1-myo-inositol) may be used as a nonendogenous phospholipid (PL) standard for the quantitative analysis of PLs. It may also be used as a standard for tandem mass spectrometry analysis of lipid species in human plasma.Biochem/physiol ActionsIncreased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) is expected to play a vital role in various diseases. Ca2+ channels at the plasma membrane and mitochondrial membrane are controlled by LPI. It can also stimulate various signaling pathways to control several cellular processes. LPI can block the migration of cells.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-500ug)Параметрыassay >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850101P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850101P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCC)=O.[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
13:0 Lyso PS 858140P-1MG
Empirical Formula (Hill Notation): C19H37NNaO9P CAS Number: 1246298-14-5 Molecular Weight: 477.46 NACRES: NA.25 Application13:0 Lyso PS has been used as an internal standard for lipid extraction using electrophoresis. It has also been used as a standard to optimize the conditions for the synthesis, purification and mass spectrometric characterization of stable isotope-labeled amadori-glycated phospholipids.Packaging5 mL Amber Glass Screw Cap Vial (858140P-1mg)Параметрыassay 99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC) form powder packaging pkg of 1 x 1 mg (858140P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
13:0 PC 850340C-25MG
Empirical Formula (Hill Notation): C34H68NO8P CAS Number: 71242-28-9 Molecular Weight: 649.88 NACRES: NA.25 General description13:0 PC is ditridecanoyl phosphatidyl choline (DTPC). Phosphatidylcholine (PC) is a phospholipid, present in endothelial cells, corneal epithelial cells, and fibroblast. Structurally, PC has a polar head consisting of choline and phosphate and two non-polar tails consisting of fatty acids. The polar head group is water soluble and the non-polar tails are water insoluble. Due to its amphiphilic properties, it is present in the cell membrane. In the human body, liver synthesizes PC. Dietary sources of PC are egg and soybeans.
Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It can form strong bilayer and is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application13:0 Phosphatidylcholine (PC) has been used as a lipid standard for mass spectrometry.
13:0 PC (1,2-ditridecanoyl-sn-glycero-3-phosphocholine) may be used as a lipid standard for the quantification of phosphatidylcholines (PCs) by mass spectrometric analysis.Biochem/physiol ActionsPhosphatidylcholine (PC) can serve as a surfactant in the mucus.
Phosphatidylcholine (PC) is the precursor for the triacylglycerol synthesis. The concentration of PC decreases owing to enhanced triacylglycerol production in the liver. Phosphatidylcholine may be a biomarker for the diagnosis of fatty liver. Its structure enables them to be used in food industry as emulsifiers.Packaging5 mL Clear Glass Sealed Ampule (850340C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (850340C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (850340C-25mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
13:0 PC
Empirical Formula (Hill Notation): C34H68NO8P CAS Number: 71242-28-9 Molecular Weight: 649.88 NACRES: NA.25
Кат. номер 850340P-200MG 850340P-500MG 850340P-25MG General descriptionPhosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application13:0 PC is suitable for use:- in the preparation of the giant unilamellar vesicles (GUVs)
- in the preparation of lipid monolayers
- as an internal standard for the extraction of total lipids from biological samples
Biochem/physiol ActionsPhosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.Packaging20 mL Clear Glass Screw Cap Vial (850340P-500mg)
5 mL Amber Glass Screw Cap Vial (850340P-200mg)
5 mL Amber Glass Screw Cap Vial (850340P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (850340P-200mg), pkg of 1 x 25 mg (850340P-25mg), pkg of 1 x 500 mg (850340P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCCC)=O)=O
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14(15) EET 900127E-500UG
Empirical Formula (Hill Notation): C20H32O3 Molecular Weight: 320.47 General descriptionEpoxytrienoic acid (EET) is produced from arachidonic acid. 14(15) EET is an EET, which is produced by five cytochrome P450 (CYP) epoxygenases. It is a regioisomer of EET synthesized in mammalian tissues.Biochem/physiol ActionsEpoxytrienoic acid (EET) plays a role as lipid mediator in the renal and cardiovascular systems. 14(15) EET activates many signal transduction pathways by binding to the membrane receptors. It possesses vasoactive properties.Packaging2ML Amber Glass Sealed Ampule (900127E-500UG)Параметрыform ethanol solution packaging pkg of 1 x 500 µg (900127E-500UG) Торговая марка Avanti Polar Lipids concentration 500 µg/mL (900127E-500UG) application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P233 - P280 - P303 + P361 + P353 - P337 + P313 - P370 + P378 WGK Germany WGK 3 Flash Point F 55.4 °F Flash Point C 13 °C Узнать цену -
14-dehydro zymostenol
Empirical Formula (Hill Notation): C27H44O Molecular Weight: 384.64
Кат. номер 700188P-5MG 700188P-1MG Packaging5 mL Amber Glass Screw Cap Vial (700188P-1MG)
5 mL Amber Glass Screw Cap Vial (700188P-5MG)Параметрыform powder packaging package of 1 x 1 mg (700188P-1MG), package of 1 x 5 mg (700188P-5MG) Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. −20°C SMILES string C[C@]1(CC2)C(C3=C2[C@]4(C)C(CC3)C[C@@H](O)CC4)=CCC1C(CCCC(C)C)C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
14-demethyl-lanosterol 700073P-1MG
Empirical Formula (Hill Notation): C29H48O CAS Number: 7448-02-4 Molecular Weight: 412.69 NACRES: NA.25 General description14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion.Application14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib.Packaging5 mL Amber Glass Screw Cap Vial (700073P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (700073P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −70°C SMILES string C[C@]12CCC([C@](CC[C@H](O)C3(C)C)(C)C3CC4)=C4C1CC[C@]2([H])[C@]([H])(C)CCC=C(C)C InChI 1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1 InChI key CHGIKSSZNBCNDW-QGBOJXOESA-N
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14-demethyl-lanosterol-d6 700074P-1MG
Empirical Formula (Hill Notation): C29H42D6O CAS Number: 1246298-30-5 Molecular Weight: 418.73 NACRES: NA.25 General description14-demethyl-lanosterol (D6) is a deuterated natural sterol.Packaging5 mL Amber Glass Screw Cap Vial (700074P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (700074P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −70°C SMILES string C[C@]12CCC([C@](CC[C@H](O)C3(C([2H])([2H])[2H])C([2H])([2H])[2H])(C)C3CC4)=C4C1CC[C@]2([H])[C@]([H])(C)CCC=C(C)C
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14:0 BMP (S,R)
Empirical Formula (Hill Notation): C34H70NO10P CAS Number: 325466-03-3 Molecular Weight: 683.89 NACRES: NA.25
Кат. номер 857131P-5MG 857131P-10MG General descriptionBis(monoacylglycerol)phosphate (BMP)/lysobisphosphatidic acid is a phospholipid, that has two phosphate-linked glycerol molecules. This phosphate-linked glycerol molecules are present in an unusual sn-1 glycerophospho-sn-1 glycerol stereo conformation, and each glycerol molecule esterified with fattyacid. It is usually seen in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.Biochem/physiol ActionsBis(monoacylglycerol)phosphate (BMP)/lysobisphosphatidic acid actively participates in cargo sorting by inducing the degradation and sorting of lipids. It also plays a major role in polyunsaturated fatty acid (PUFA) sorting in acidic organelles.Packaging5 mL Amber Glass Screw Cap Vial (857131P-10mg)
5 mL Amber Glass Screw Cap Vial (857131P-5mg)Параметрыassay >99% (BMP (contains 30% positional isomers), TLC) form powder packaging pkg of 1 x 10 mg (857131P-10mg), pkg of 1 x 5 mg (857131P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCCCCCCCC)=O.[NH4+]
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14:0 Cardiolipin (ammonium salt) 710332C-25MG
Empirical Formula (Hill Notation): C65H132N2O17P2 CAS Number: 63988-20-5 Molecular Weight: 1275.69 NACRES: NA.25 General description14:0 Cardiolipin is an acidic phospholipid. Structurally, cardiolipin comprises three glycerol moieties and four acyl chains and is localized in the inner membrane of mitochondria. 14:0 Cardiolipin contains four myristic acid as acyl chain.Application14:0 Cardiolipin (1,3-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)) has been used:- as a standard in tandem mass spectrometry
- in the preparation of membrane proximal region (MPR) of human immunodeficiency virus (HIV-1) glycoprotein 41 (gp41)-lipopeptide conjugate and liposomes
- as a component of micelle for suspending C8 ceramide substrate in ceramide kinase assay
Biochem/physiol ActionsCardiolipin (CL) plays a key role in oxidative phosphorylation. CL is essential for energy production and in the activation of apoptosis. Deficiency of CL is associated with the development of diabetes and age-related heart failure. Anomalies associated with CL composition is observed in Barth Syndrome (BTHS).Packaging5 mL Clear Glass Sealed Ampule (710332C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (710332C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (710332C-25mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
14:0 Cardiolipin (ammonium salt)
Empirical Formula (Hill Notation): C65H132N2O17P2 CAS Number: 63988-20-5 Molecular Weight: 1275.69 NACRES: NA.25
Кат. номер 710332P-25MG 710332P-200MG General description14:0 Cardiolipin or TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) is a saturated CL and exists as gel at low temperatures.
Cardiolipin is an anionic phospholipid. The 14:0 indicates the fatty acyl substituents attached to the carbons of glycerol. It is localized to the inner mitochondrial membrane.Application14:0 Cardiolipin (ammonium salt) has been used as stable isotope-labeled standard prior to yeast strains high performance liquid chromatography electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS). It may be used as an internal standard in mass spectroscopy and in liposome preparation for electrophysiological studies.
14:0 Cardiolipin (ammonium salt) may be used in lipopeptide synthesis.Biochem/physiol ActionsTMCL (1,1,2,2-tetramyristoyl cardiolipin) bilayers are useful in generating multilamellar vesicles. Defects in the cardiolipin metabolic associated with Barth syndrome patients. Liposomes of TMCL with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and cholesterol are potential drug-delivery systems. TMCL displays temperature dependent thermotropic phase transitions.
Cardiolipin participates in proton uptake pathway and also maintains the structure of enzymes involved. Cardiolipin maintains the mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy.) Cardiolipin can form micelles/vesicles naturally.Packaging5 mL Amber Glass Screw Cap Vial (710332P-25mg)
5 mL Amber Glass Screw Cap Vial (710332P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (710332P-200mg), pkg of 1 x 25 mg (710332P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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14:0 Cardiolipin (sodium salt)
Empirical Formula (Hill Notation): C65H124Na2O17P2 CAS Number: 63988-21-6 Molecular Weight: 1285.60
Кат. номер 750332P-200MG 750332P-1G 750332P-500MG 750332P-25MG Application14:0 Cardiolipin (sodium salt) has been used:- as an internal standard for the quantitative analysis of cardiolipin (18:2)4 or CL (18:2)4 in human leukocytes and mouse mitochondria
- for chemiluminescent assay
- for the preparation of liposomes
Packaging20 mL Clear Glass Screw Cap Vial (750332P-500mg)
5 mL Amber Glass Screw Cap Vial (750332P-200mg)
5 mL Amber Glass Screw Cap Vial (750332P-25mg)
20 mL Clear Glass Screw Cap Vial (750332P-1g)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 g (750332P-1g), pkg of 1 x 200 mg (750332P-200mg), pkg of 1 x 25 mg (750332P-25mg), pkg of 1 x 500 mg (750332P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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14:0 Coenzyme A 870714P-5MG
Empirical Formula (Hill Notation): C35H71N10O17P3S CAS Number: 799812-85-4 Molecular Weight: 1028.98 NACRES: NA.25 General description14:0 Coenzyme A, also known as myristoyl coenzyme A, is a coenzyme A derivative of myristic acid. 14:0 Coenzyme A is a long-chain acyl CoA.Application14:0 Coenzyme A may be used as a standard in quantitative ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for simultaneous analysis of tissue long-chain acyl-CoA (LCACoA) concentration.Biochem/physiol Actions14:0 Coenzyme A is an important lipid metabolite. It acts as a N-myristoyltransferase substrate during myristoylation. Myristoylation is a protein lipid modification involving the addition of myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells.Packaging5 mL Amber Glass Screw Cap Vial (870714P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (870714P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
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14:0 DAP 890840P-25MG
Empirical Formula (Hill Notation): C33H65NO4 CAS Number: 72719-84-7 Molecular Weight: 539.87 NACRES: NA.25 Application1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) might be used:- to prepare liposomal membrane and study its interaction between surfactants
- to study its effect on the ordering of two-dimensional dispersions of membrane-coated particles
- to study its interaction with mastoparan (MP)
Biochem/physiol Actions1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.Packaging5 mL Clear Glass Sealed Ampule (890840P-25mg)Параметрыform powder packaging pkg of 1 x 25 mg (890840P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H]C(CN(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
14:0 DAP 890840C-25MG
Empirical Formula (Hill Notation): C33H65NO4 CAS Number: 72719-84-7 Molecular Weight: 539.87 NACRES: NA.25 Application1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) might be used:- to prepare liposomal membrane and to study its interaction between surfactants
- to study its effect on the ordering of two-dimensional dispersions of membrane-coated particles
- to study its interaction with mastoparan (MP)
Biochem/physiol Actions1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.Packaging5 mL Clear Glass Sealed Ampule (890840C-25mg)Параметрыpackaging pkg of 1 x 2.5 mL (890840C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (890840C-25mg) shipped in dry ice storage temp. −20°C SMILES string [H]C(CN(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
14:0 DG
Empirical Formula (Hill Notation): C31H60O5 CAS Number: 60562-16-5 Molecular Weight: 512.81 NACRES: NA.25
Кат. номер 800814P-25MG 800814P-10MG General descriptionIn biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane.
Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.
1,2-dimyristoyl-sn-glycerol (14:0 DG) with small polar headgroup and two fatty acid, is an E coli membrane lipid.Application14:0 DG may be used:- in the reconstitution of dry lipids for thin layer chromatography
- in lipid nanoparticles for RNA delivery studies
- as a standard in gas chromatography–mass spectrometry (GC-MS) analysis for the quantification of lipid A diacylglycerols
Biochem/physiol ActionsDiacylglycerol (DAG) displays a flip-flop motion. This movement of DAG is inhibited by membrane protein integrase (mini-MPIase-3).It also forms nonlamellar phase.Packaging5 mL Amber Glass Screw Cap Vial (800814P-25mg)
5 mL Amber Glass Screw Cap Vial (800814P-10mg)Storage and StabilityDiacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.Other NotesEffective concentration:
Most biological responses saturate at 20 to 250 µM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (800814P-10mg), pkg of 1 x 25 mg (800814P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
14:0 Diether PC
Empirical Formula (Hill Notation): C36H76NO6P CAS Number: 36314-48-4 Molecular Weight: 649.97 NACRES: NA.25
Кат. номер 999993C-25MG 999993C-10MG General description14:0 Diether PC (phosphocholine) is a glycerophospholipid having two tetradecyl chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.Application14:0 Diether PC or 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine might be used:- in lipid bicelles to reconstitute EmrE (secondary active transport protein) to study the chain length dependence by differential scanning calorimetry and solid-state nuclear magnetic resonance (NMR)
- to compose isotropically tumbling small bicelles, to study its size and morphology
- to prepare bicelle samples for solid-state NMR experiments to determine if the proteins could be reconstituted into phospholipid bilayers
Packaging5 mL Clear Glass Sealed Ampule (999993C-25mg)
5 mL Clear Glass Sealed Ampule (999993C-10mg)Параметрыpackaging pkg of 1 x 1 mL (999993C-10mg), pkg of 1 x 2.5 mL (999993C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (999993C-10mg), 10 mg/mL (999993C-25mg) shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCC)COCCCCCCCCCCCCCC)=O
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
14:0 Diether PG 999800P-25MG
Empirical Formula (Hill Notation): C34H70O8PNa CAS Number: 384835-62-5 Molecular Weight: 660.88 NACRES: NA.25 Application14:0 Diether PG might be used in biotinylated liposome preparation. It is also suitable for use in the preparation of solid-state nuclear magnetic resonance (SSNMR) samples.Biochem/physiol Actions1,2-di-O-tetradecyl-sn-glycero-3-phospho-(1-rac-glycerol) or 14:0 Diether PG is an anionic lipid used for bicelle preparations. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.Packaging5 mL Amber Glass Screw Cap Vial (999800P-25mg)Параметрыform powder packaging pkg of 1 x 25 mg (999800P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC(O)CO)=O)(OCCCCCCCCCCCCCC)COCCCCCCCCCCCCCC.[Na+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
14:0 EPC (Cl Salt)
Empirical Formula (Hill Notation): C38H77NO8PCl CAS Number: 186492-53-5 Molecular Weight: 742.45 NACRES: NA.25
Кат. номер 890701P-25MG 890701P-10MG General description1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC) is an acyl cationic lipid. O-alkyl phosphatidylcholines constitute the first chemically stable tri-esters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.Application1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC (Cl Salt)) is suitable for use in liposome formulations.Biochem/physiol ActionsSynthetic cationic lipids serve as non-viral gene delivery agents. Change in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency. 1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC) aids in hydration during the formation of liposomes.Packaging5 mL Clear Glass Sealed Ampule (890701P-10mg)
5 mL Clear Glass Sealed Ampule (890701P-25mg)Параметрыform powder packaging pkg of 1 x 10 mg (890701P-10mg), pkg of 1 x 25 mg (890701P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)OCC.[Cl-]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
14:0 Ether Coenzyme A 870735P-5MG
Empirical Formula (Hill Notation): C35H73N10O16P3S CAS Number: 852043-48-2 Molecular Weight: 1015.00 NACRES: NA.25 General description14:0 Ether Coenzyme A, also known as tetradecyl coenzyme A (CoA), is a long-chain acyl-CoA ester and a thioether analog of myristoyl coenzyme A. Long-chain acyl-CoA esters play an important role in a plethora of cellular functions. These lipids are involved in regulation of fatty acid synthesis, enzyme systems, vesicle trafficking, ion channels and ion pumps.Packaging5 mL Amber Glass Screw Cap Vial (870735P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (870735P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSCCCCCCCCCCCCCC)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
14:0 Hemi BMP (S,R) 857132P-5MG
Empirical Formula (Hill Notation): C48H96NO11P CAS Number: 325466-04-4 Molecular Weight: 894.25 NACRES: NA.25 General descriptionHemi-bis(monoacylglycero)phosphate (hemi-BMP) consists of a glycerophosphoglycerol backbone wherein the three fatty acyl chains are esterified to the glycerol hydroxyls.Packaging5 mL Amber Glass Screw Cap Vial (857132P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (857132P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCCCCCCCC)=O)([O-])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
14:0 Hemi BMP (S,R) 857132C-5MG
Empirical Formula (Hill Notation): C48H96NO11P CAS Number: 325466-04-4 Molecular Weight: 894.25 NACRES: NA.25 General descriptionBis(monoacylglycerol) phosphate (BMP) is a phospholipid, containing two-phosphate linked fatty acid esterified glycerol molecule. It is present in late endosome, majorly in intraluminal vesicles (ILVs) and is hydrolyzed by BMP hydrolase. BMP accounts to 15% of total organelle lipids.Application14:0 Hemi BMP (S,R) is suitable to use as ISTDs (internal standards) for the extraction of phospholipids.Biochem/physiol ActionsBis(monoacylglycerol)phosphate (BMP) plays a key role in cargo sorting and protein and lipid trafficking. The levels of BMP is elevated in lysosomal storage disorders (LSD) including Wolman disease, Niemann Pick disease and neuronal ceroid lipofuscinoses. It is resistant to degradation by the enzyme, acid phospholipase.Packaging5 mL Clear Glass Sealed Ampule (857132C-5mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (857132C-5mg) Торговая марка Avanti Polar Lipids concentration 5 mg/mL (857132C-5mg) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCCCCCCCC)=O)([O-])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
14:0 Liss Rhod PE
Empirical Formula (Hill Notation): C60H97N4O14PS2 CAS Number: 474942-83-1 Molecular Weight: 1193.53 NACRES: NA.25
Кат. номер 810157C-5MG 810157C-1MG Application14:0 Liss Rhod PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) (ammonium salt) has been used in the preparation of nanoemulsion to visualize its cellular uptake by microscopy. 14:0 Liss Rhod PE is also suitable for the preparation of: labeled phospholipid vesicle for lipid mixing assay, supported lipid bilayer (SLB) vesicles for surface plasmon resonance (SPR)-binding experiments, red labeled liposomePackaging5 mL Amber Glass Screw Cap Vial (810157C-5mg)
5 mL Amber Glass Screw Cap Vial (810157C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810157C-1mg), pkg of 5 x 1 mL (810157C-5mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810157C-1mg), 1 mg/mL (810157C-5mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
14:0 Lyso PA
Empirical Formula (Hill Notation): C17H34O7PNa CAS Number: 325465-45-0 Molecular Weight: 404.41 NACRES: NA.25
Кат. номер 857120P-500MG 857120P-25MG General descriptionLysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.Application14:0 Lyso PA is suitable to use as internal standard to spike serum samples for the extraction of serum lipids. It is also suitable to use as standard lipids for extraction of lipids and for quality control in multiple reaction monitoring (MRM) assay.Biochem/physiol ActionsLysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca2+ mobilization, neurotransmitter release and cell proliferation.Packaging20 mL Clear Glass Screw Cap Vial (857120P-500mg)
5 mL Amber Glass Screw Cap Vial (857120P-25mg)Параметрыassay >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC) form powder packaging pkg of 1 x 25 mg (857120P-25mg), pkg of 1 x 500 mg (857120P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
14:0 Lyso PC
Empirical Formula (Hill Notation): C22H46NO7P CAS Number: 20559-16-4 Molecular Weight: 467.58 NACRES: NA.25
Кат. номер 855575P-200MG 855575P-500MG 855575P-1G 855575P-25MG Application14:0 Lyso PC may be used:- as a component of detergent micelle to analyze the secondary structure of the purified twin-arginine translocation (Tat) membrane protein (TatCd) by circular dichroism (CD)
- for the synthesis of three monofluorinated dimyristoylphosphatidylcholines (F-DMPCs), such as 2F-DMPC, 12F-DMPC and 14F-DMPC
- as a component of dry lipid film for the synthesis of palladium (Pd)-pyrolipid theranostic nanoparticles (PdPL-NPs) and manganese-pyrolipid surface-enhanced Raman scattering (SERS) NPs (MnPL-NPs)
14:0 Lyso PC has been used to study its role in nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) and serine/threonine-protein kinase akt-1 signals in rat pheochromocytoma PC12 cells.Packaging5 mL Amber Glass Screw Cap Vial (855575P-200mg)
20 mL Clear Glass Screw Cap Vial (855575P-500mg)
5 mL Amber Glass Screw Cap Vial (855575P-25mg)
20 mL Clear Glass Screw Cap Vial (855575P-1g)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 1 g (855575P-1g), pkg of 1 x 200 mg (855575P-200mg), pkg of 1 x 25 mg (855575P-25mg), pkg of 1 x 500 mg (855575P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
14:0 Lyso PE
Empirical Formula (Hill Notation): C19H40NO7P CAS Number: 123060-40-2 Molecular Weight: 425.50
Кат. номер 856735P-25MG 856735P-200MG Application14:0 Lyso PE has been used for lipidomic profiling. It has also been used for the preparation of lipids.Packaging5 mL Amber Glass Screw Cap Vial (856735P-200mg)
5 mL Amber Glass Screw Cap Vial (856735P-25mg)Параметрыassay >99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC) form powder packaging pkg of 1 x 200 mg (856735P-200mg), pkg of 1 x 25 mg (856735P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
14:0 Lyso PG
Empirical Formula (Hill Notation): C20H40O9PNa CAS Number: 326495-21-0 Molecular Weight: 478.49 NACRES: NA.25
Кат. номер 858120P-500MG 858120P-1G General description14:0 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are non bilayer forming lipids, that are synthesized in γ-proteobacteria. They are minimally found in very minute amounts in normal bacterial membranes.Application14:0 Lyso PG has been used as a standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.Biochem/physiol ActionsLyso phosphoglycerol (Lyso PG) acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) for the synthesis of phosphoglycerol.Packaging20 mL Clear Glass Screw Cap Vial (858120P-1g)
20 mL Clear Glass Screw Cap Vial (858120P-500mg)Параметрыassay >99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC) form powder packaging pkg of 1 x 1 g (858120P-1g), pkg of 1 x 500 mg (858120P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
14:0 NBD PE
Empirical Formula (Hill Notation): C39H70N5O11P CAS Number: 474942-82-0 Molecular Weight: 815.97 NACRES: NA.25
Кат. номер 810143C-5MG 810143C-1MG Application14:0 NBD PE is suitable for the preparation of phospholipid vesicles for lipid mixing assay. It is also suitable to use as fluorescent phospholipid derivative to study the effect of its exchange between β-lactoglobulin (β-LG) and phosphatidylcholine (POPC) bilayers.Biochem/physiol ActionsNBD PE (1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl)) can be used liposome preparation. In which, it might serve as a measure of steady-state fluorescence anisotropy. This might be useful to analyse the mitochondrial membrane structure.Packaging5 mL Amber Glass Screw Cap Vial (810143C-5mg)
5 mL Amber Glass Screw Cap Vial (810143C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810143C-1mg), pkg of 5 x 1 mL (810143C-5mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810143C-1mg), 1 mg/mL (810143C-5mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
14:0 NPS PC
Empirical Formula (Hill Notation): C32H53N2O12P CAS Number: 273931-53-6 Molecular Weight: 688.74 NACRES: NA.25
Кат. номер 810857P-100MG 810857P-25MG 810857P-200MG Packaging5 mL Clear Glass Sealed Ampule (810857P-100mg)
5 mL Clear Glass Sealed Ampule (810857P-25mg)
5 mL Clear Glass Sealed Ampule (810857P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 mg (810857P-100mg), pkg of 2 x 100 mg (810857P-200mg), pkg of 1 x 25 mg (810857P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
14:0 PA
Empirical Formula (Hill Notation): C31H60O8PNa CAS Number: 80724-31-8 Molecular Weight: 614.77
Кат. номер 830845P-25MG 830845P-200MG General descriptionPhosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D. 14:0 PA/a negatively charged 1,2-dimyristoyl-sn-glycero-3-phosphate (DMPA) carries a phosphoric acid head group.Application14:0 PA may be used to prepare liposomes. It may also be used as a phospholipid (PL) standard to quantify phosphatidic acid (PA).Biochem/physiol ActionsPhosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid.Packaging5 mL Amber Glass Screw Cap Vial (830845P-25mg)
5 mL Amber Glass Screw Cap Vial (830845P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (830845P-200mg), pkg of 1 x 25 mg (830845P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
14:0 PA-d54 860450P-10MG
Empirical Formula (Hill Notation): C31H6O8PNaD54 CAS Number: 327178-99-4 Molecular Weight: 669.10 NACRES: NA.25 General description1,2-dimyristoyl-d54-sn-glycero-3-phosphate (sodium salt) (14:0 PA-d54) is a deuterated phosphatidic acid in which 54 protons of dimyristoyl are replaced by deuterium isotope. Phosphatidic acid (PA) is a membrane phospholipid.Biochem/physiol ActionsPhosphatidic acid (PA) serves as an intermediate for the production of storage and membrane lipids. It is involved in the regulation of glycerolipid metabolism. PA is also involved in membrane biogenesis. It is also implicated in several cellular processes such as, membrane trafficking, signal transduction, cytoskeletal rearrangement and secretion.Packaging5 mL Amber Glass Screw Cap Vial (860450P-10MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (860450P-10MG) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP(O)([O-])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену
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