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10:0 (3-Oxo) CoA 870750P-1MG
Empirical Formula (Hill Notation): C31H61N10O18P3S CAS Number: 50411-91-1 Molecular Weight: 986.86 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (870750P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (870750P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CC(CCCCCCC)=O)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
10:0 Coenzyme A
Empirical Formula (Hill Notation): C31H63N10O17P3S CAS Number: 799812-83-2 Molecular Weight: 972.88 NACRES: NA.25
Кат. номер 870710P-10MG 870710P-5MG General description10:0 Coenzyme A, also known as decanoyl Coenzyme A, is a coenzyme A derivative of decanoic acid. It is a medium-chain acyl CoA and is an intermediate of fatty acid metabolism. Decanoyl-CoA acts as a CqsA (acyl-CoA transferase) substrate for the synthesis of 3-aminotridecan-4-one (amino-CAI-1).ApplicationDecanoyl Coenzyme A has been used as an internal standard to measure the decanoyl-CoA in the standard mixture analyzed with reversed phase ultrahigh performance liquid chromatography (UHPLC).Packaging5 mL Amber Glass Screw Cap Vial (870710P-5mg)
5 mL Amber Glass Screw Cap Vial (870710P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (870710P-10mg), pkg of 1 x 5 mg (870710P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
10:0 DG 800810C-10MG
Empirical Formula (Hill Notation): C23H44O5 CAS Number: 60514-49-0 Molecular Weight: 400.59 NACRES: NA.25 General descriptionIn biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane.
Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.
10:0 DG (DDG), also called 1,2-didecanoyl-sn-glycerol, is a substrate for human pancreatic lipase (HPL).Application10:0 DG has been used in the monomolecular film preparation for enzyme assay studies. It may be used in diacylglycerol kinase (DGK) activity assay in DDT1-MF2 cells and in glomerulus homogenate from diabetic rats.Packaging30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (800810C-10mg)Storage and StabilityDiacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.Other NotesEffective concentration:
Most biological responses saturate at 20 to 250 µM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.Параметрыassay >99% (TLC) packaging pkg of 1 x 5 mL (800810C-10mg) Торговая марка Avanti Polar Lipids concentration 2 mg/mL (800810C-10mg) shipped in dry ice storage temp. 20°C InChI 1S/C23H44O5/c1-3-5-7-9-11-13-15-17-22(25)27-20-21(19-24)28-23(26)18-16-14-12-10-8-6-4-2/h21,24H,3-20H2,1-2H3/t21-/m0/s1 InChI key GNSDEDOVXZDMKM-NRFANRHFSA-N
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
10:0 DG 800810P-10MG
Empirical Formula (Hill Notation): C23H44O5 CAS Number: 60514-49-0 Molecular Weight: 400.59 NACRES: NA.25 General descriptionIn biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane.
Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.
10:0 DG (DDG), also called 1,2-didecanoyl-sn-glycerol, is a substrate for human pancreatic lipase (HPL).Application10:0 DG may be used in the diacylglycerol kinase (DGK) activity in DDT1-MF2 cells and in glomerulus homogenate from diabetic rats. It may be also used in monolayers as substrate for human pancreatic lipase (HPL).Packaging5 mL PTFE Vial with Screw Cap (800810P-10mg)Storage and StabilityDiacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.Other NotesEffective concentration:
Most biological responses saturate at 20 to 250 µM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (with screw cap (800810P-10mg)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C InChI 1S/C23H44O5/c1-3-5-7-9-11-13-15-17-22(25)27-20-21(19-24)28-23(26)18-16-14-12-10-8-6-4-2/h21,24H,3-20H2,1-2H3/t21-/m0/s1 InChI key GNSDEDOVXZDMKM-NRFANRHFSA-N
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
10:0 Lyso PC
Empirical Formula (Hill Notation): C18H38NO7P CAS Number: 22248-63-1 Molecular Weight: 411.47
Кат. номер 855375P-500MG 855375P-25MG General descriptionLyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head.Application10:0 Lyso PC has been used as an internal standard to quantify the most abundant lysophosphatidylcholine (LPC) species found in Trypanosoma cruzi samples.Biochem/physiol ActionsLysophosphatidylcholine (LPC) alters various biological functions in different cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.Packaging5 mL Clear Glass Sealed Ampule (855375P-25mg)
20 mL Clear Glass Screw Cap Vial (855375P-500mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855375P-25mg), pkg of 1 x 500 mg (855375P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
10:0 PA
Empirical Formula (Hill Notation): C23H44O8PNa CAS Number: 321883-64-1 Molecular Weight: 502.55 NACRES: NA.25
Кат. номер 830843C-25MG 830843C-500MG General descriptionPhosphatidic acid (PA) is a diacyl-glycerophospholipid. With the help of ester linkage, two fatty acids and a phosphate group are attached to a glycerol molecule through covalent bonds. PA is rich in soy lecithin. It can be produced through phosphorylation of diacyl glycerol (DAG) with the help of diacylglycerol kinases (DGKs).Application10:0 PA has been used for preparation of the ubiquitin specific peptidase 1-mitochondrial distribution and morphology protein 35 (Ups1–Mdm35)– phosphatidic acid (PA) complex.
It may be used:- as a component in the lipid bilayer to study how lipid geometry acts in coat protein I (COPI) vesicle fission
- to study its effects on intracellular Ca2+ concentration ([Ca2+]i) in C6 rat glioma and L2071 mouse fibroblast cells
- to activate protein kinase C (PKC) in chinese hamster ovary (CHO) cells
Biochem/physiol ActionsPhosphatidic acid (PA) is present in biomembranes. It is the precursor for other phospholipids and acts as a signaling molecule. PA is implicated in nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) activity. 10:0 PA along with 1-oleoyl-2-acetoyl-sn-glycerol (OAG) and arachidonic acid (AA) can be used as cell-free activators to promote NADPH oxidase activity.Packaging30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (830843C-500mg)
5 mL Clear Glass Sealed Ampule (830843C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (830843C-25mg), pkg of 1 x 20 mL (830843C-500mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (830843C-25mg), 25 mg/mL (830843C-500mg) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
10:0 PC
Empirical Formula (Hill Notation): C28H56NO8P CAS Number: 3436-44-0 Molecular Weight: 565.72 NACRES: NA.25
Кат. номер 850325P-200MG 850325P-25MG General description10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) is a zwitterionic and shorter-acyl chain phospholipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) may be used:- as an internal standard to measure lipid metabolites for metabolic profiling using hydrophilic interaction liquid chromatography (HILIC)
- to prepare lipid bilayer to reconstitute Vpu (membrane protein) and for biophysical studies
- to prepare phospholipid membrane to study lipid-induced conformation of a 27-residue Cry4Ba-7 peptide
Biochem/physiol ActionsHigh or low level of phosphatidylcholine (PC) can affect energy metabolism in several organelles.Packaging5 mL Clear Glass Sealed Ampule (850325P-25mg)
20 mL Clear Glass Screw Cap Vial (850325P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (850325P-200mg), pkg of 1 x 25 mg (850325P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O InChI 1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3 InChI key MLKLDGSYMHFAOC-UHFFFAOYSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
10:0 PE 850700P-25MG
Empirical Formula (Hill Notation): C25H50NO8P CAS Number: 253685-27-7 Molecular Weight: 523.64 NACRES: NA.25 General descriptionPhosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.Application10:0 PE has been used for the synthesis of fluorescent phospholipid derivative NBD-didecanoylphosphatidylethanolamine (NBD-diC10PE).Biochem/physiol ActionsPhosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.Packaging5 mL Clear Glass Sealed Ampule (850700P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 25 mg (850700P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
10:0 PE 850700C-25MG
Empirical Formula (Hill Notation): C25H50NO8P CAS Number: 253685-27-7 Molecular Weight: 523.64 NACRES: NA.25 General description1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (10:0 PE) is a soluble short-chain phospholipid.Application1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (10:0 PE) may be used as an internal standard for the quantitative analysis of phospholipids by electrospray ionization-tandem mass spectrometry (ESI-MS/MS). It may also be used to titrate the lantibiotic cinnamycin (Ro 09-0198) in isothermal titration calorimetry.Biochem/physiol ActionsPhosphatidylethanolamine (PE) controls membrane fluidity in eukaryotic cells.Packaging5 mL Clear Glass Sealed Ampule (850700C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (850700C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (850700C-25mg) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
10:0 PG
Empirical Formula (Hill Notation): C26H50O10PNa CAS Number: 322647-25-6 Molecular Weight: 576.63 NACRES: NA.25
Кат. номер 840434C-25MG 840434C-500MG General descriptionPhosphatidylglycerol (PG), an anionic lipid is present in the membranes of mammals. It accounts for 1–2% of the total phospholipids.Application10:0 PG (1,2-didecanoyl-sn-glycero-3-phospho-(1-rac-glycerol)) may be used as a component in the liposomes, labeled with -pyrene-C10-PG. It may also be used as a lipid standard to compare accurate lipid quantification with deuterated standard lipids using electrospray ionization (ESI).Biochem/physiol ActionsIn cyanobacteria and plants, phosphatidylglycerol (PG) plays a key role in the formation and activities of thylakoid membranes. Absence of PG can bring a change in the function of photosystem (PS) I and PSII reaction centers (RCs).Packaging30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840434C-500mg)
5 mL Clear Glass Sealed Ampule (840434C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (840434C-25mg), pkg of 1 x 20 mL (840434C-500mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (840434C-25mg), 25 mg/mL (840434C-500mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
10:0 PS 840036P-10MG
Empirical Formula (Hill Notation): C26H49NO10PNa CAS Number: 321863-22-3 Molecular Weight: 589.63 NACRES: NA.25 General descriptionGlycerophosphoserines (PS) associates with spectrin and maintains the membrane asymmetry of red blood cells (RBC).Application1,2-didecanoyl-sn-glycero-3-phospho-L-serine has been used as a component in internal lipid standard mixture for matrix-assisted laser desorption/ionization (MALDI)-fourier-transform ion cyclotron resonance (FTICR)-mass spectrometry (MS) analysis.Packaging5 mL Clear Glass Sealed Ampule (840036P-10mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (840036P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
10MAG 850544O-1G
Empirical Formula (Hill Notation): C13H26O4 CAS Number: 17863-69-3 Molecular Weight: 246.34 NACRES: NA.25 General descriptionMonoglycerides/monoacylglycerols are polar lipids and are amphiphilic in nature.10MAG (1-decanoyl-rac-glycerol) is a nonionic surfactant.
An optimized reverse micelle surfactant system has been developed for solution nuclear magnetic resonance studies of encapsulated proteins and nucleic acids dissolved in low viscosity fluids. Comprising the nonionic 1-decanoyl-rac-glycerol and the zwitterionic lauryldimethylamine-N-oxide (10MAG/LDAO), this mixture is shown to efficiently encapsulate a diverse set of proteins and nucleic acids. Chemical shift analyses of these systems show that high structural fidelity is achieved upon encapsulation.Application10MAG (1-decanoyl-rac-glycerol) may be used:- as a substrate for fluorescent glycerol assay
- as a standard for the quantification of monoacylglycerols (MAGs) in micellar fraction analysis
- as a component in the surfactant mixture for reverse micelle sample preparation
Biochem/physiol ActionsMonoglycerides are major component of baking mixtures.Packaging5 mL PTFE Vial with Screw Cap (850544O-1g)Параметрыassay >99% (TLC) mol wt 246.34 g/mol packaging pkg of 10 x 0.1 g (with screw cap (850544O-1g)) Торговая марка Avanti Polar Lipids application(s) NMR: suitable, bio NMR: suitable shipped in dry ice storage temp. 20°C SMILES string O=C(OCC(O)CO)CCCCCCCCC InChI 1S/C23H44O5/c1-3-5-7-9-11-13-15-17-22(25)27-20-21(19-24)28-23(26)18-16-14-12-10-8-6-4-2/h21,24H,3-20H2,1-2H3 InChI key GNSDEDOVXZDMKM-UHFFFAOYSA-N
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
11-beta PGF2 900123P-1MG
Empirical Formula (Hill Notation): C20H34O5 Molecular Weight: 354.48 Packaging5 mL Amber Glass Screw Cap Vial (900123P-1mg)Параметрыassay >99% (TLC) Quality Level 100, form powder packaging pkg of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@H]1C[C@H](O)[C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@@H](O)CCCCC
Safety Informationpictograms GHS06,GHS09 signalword Danger hcodes H302 - H310 - H319 - H410 pcodes P262 - P273 - P280 - P301 + P312 + P330 - P302 + P352 + P310 - P305 + P351 + P338 WGK Germany WGK 3 Узнать цену -
11:0 Lyso PC 855376P-25MG
Empirical Formula (Hill Notation): C19H40NO7P CAS Number: 27869-41-6 Molecular Weight: 425.50 NACRES: NA.25 Application11:0 Lyso PC is suitable for use as a standard micelle component for the purification of human cytochrome P450s 3A4 and 1A2.Packaging5 mL Amber Glass Screw Cap Vial (855376P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855376P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
11:0 Lyso PC 855376C-25MG
Empirical Formula (Hill Notation): C19H40NO7P CAS Number: 27869-41-6 Molecular Weight: 425.50 NACRES: NA.25 Application11:0 Lyso PC may be used as a standard micelle component for the purification of human cytochrome P450s 3A4 and 1A2.Packaging5 mL Clear Glass Sealed Ampule (855376C-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) packaging pkg of 1 x 2.5 mL (855376C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (855376C-25mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
11:0 PC
Empirical Formula (Hill Notation): C30H60NO8P CAS Number: 27869-47-2 Molecular Weight: 593.77 NACRES: NA.25
Кат. номер 850330P-25MG 850330P-500MG General descriptionPhosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application11:0 PC has been used as a direct supplementation in bacteria, that are seeded onto the plates to study its effects on lipid accumulation.Biochem/physiol ActionsPhosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.Packaging30 mL Amber Wide Mouth Bottle with Screw Cap (850330P-500mg)
5 mL Clear Glass Sealed Ampule (850330P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 25 mg (850330P-25mg), pkg of 1 x 500 mg (850330P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCC)=O)COC(CCCCCCCCCC)=O)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12-ketochenodeoxycholic acid 700236P-5MG
Empirical Formula (Hill Notation): C24H38O5 Molecular Weight: 406.56 Packaging5 mL Amber Glass Screw Cap Vial (700236P-5mg)Параметрыassay >99% (TLC) Quality Level 100, form powder packaging package of 1 x 5 mg ((700236P-5MG)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS07 signalword Warning hcodes H315 - H319 pcodes P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 WGK Germany WGK 3 Узнать цену -
12-ketolithocholic acid 700239P-10MG
Empirical Formula (Hill Notation): C24H38O4 Molecular Weight: 390.56 Packaging5 mL Amber Glass Screw Cap Vial (700239P-10MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS07 signalword Warning hcodes H302 pcodes P301 + P312 + P330 WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12-NBD Stearate 810110P-1MG
Empirical Formula (Hill Notation): C25H40N4O5 CAS Number: 117056-67-4 Molecular Weight: 476.61 NACRES: NA.25 General description12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.Application12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).Biochem/physiol Actions12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.Packaging5 mL Amber Glass Screw Cap Vial (810110P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810110P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C InChI 1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31) InChI key SAAVELCIPHKGJE-UHFFFAOYSA-N
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12-NBD Stearate 810110C-1MG
Empirical Formula (Hill Notation): C25H40N4O5 CAS Number: 117056-67-4 Molecular Weight: 476.61 NACRES: NA.25 General description12-NBD Stearate is a fluorescent long-chain fatty acid (LCFA) derivative. It is amphipathic and a non-esterifiable fatty acid probe for incorporation into lipid droplets.Application12-NBD Stearate may be used:- as a ligand for fatty-acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay
- as a ligand for FABPs in spectrofluorometric measurements
- as an inhibitor for FABP3, FABP5 and FABP7
Biochem/physiol Actions12-NBD Stearate is unmetabolizable in HepG2 cells and colocalizes with α-caveolin-1 and its uptake is inhibited by filipin III. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favors NBD Stearate transport compared to its 13.2-kDa isoform. The fatty-acid binding protein (FABP) expression in differentiating embryonic stem cells (ES) regulates the uptake of NBD Stearate. NBD Stearate is used majorly in fluorescence displacement binding assays of fatty-acid binding proteins.Packaging5 mL Amber Glass Screw Cap Vial (810110C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810110C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810110C-1mg) shipped in dry ice storage temp. −20°C InChI 1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31) InChI key SAAVELCIPHKGJE-UHFFFAOYSA-N
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
12-PAHSA
Empirical Formula (Hill Notation): C34H66O4 Molecular Weight: 538.89
Кат. номер 900416O-5MG 900416O-1MG Packaging5 mL Amber Glass Screw Cap Vial (900416O-1MG)
5 mL Amber Glass Screw Cap Vial (900416O-5MG)Параметрыassay >99% (TLC) form oil packaging package of 1 x 1 mg, package of 1 x 5 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12-PAHSA (C13 labeled) 900417P-1MG
Empirical Formula (Hill Notation): C1813C16H66O4 Molecular Weight: 554.77 Packaging5 mL Amber Glass Screw Cap Vial (900417P-1MG)Параметрыassay >99% (TLC) form powder packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 Biotin-18:1 PE 860511C-1MG
Empirical Formula (Hill Notation): C45H83N4O10PS Molecular Weight: 903.20 NACRES: NA.25 Packaging5 mL Clear Glass Sealed Ampule (860511C-1MG)Параметрыassay >99% (TLC) form chloroform solution packaging pkg of 1 x 1 mL (860511C-1MG) Торговая марка Avanti Polar Lipids concentration 1 mg/mL in chloroform (860511C-1MG) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 Biotinyl Coenzyme A 860570P-1MG
Empirical Formula (Hill Notation): C43H82N13O19P3S2 CAS Number: 2260670-05-9 Molecular Weight: 1242.24 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860570P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860570P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@]1(CCCCC(NCCCCCCCCCCCC(SCCNC(CCNC([C@@]([H])(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]2OP([O-])(O)=O)O[C@H]([C@@H]2O)N3C4=C(C(N)=NC=N4)N=C3)=O)=O)C)O)=O)=O)=O)=O)SC[C@@]5([H])[C@]1([H])NC(N5)=O.[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Flash Point F No data available Flash Point C No data available Узнать цену -
12:0 Biotinyl LPA 860566P-1MG
Empirical Formula (Hill Notation): C25H49N4O9PS CAS Number: 799812-69-4 Molecular Weight: 612.72 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860566P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860566P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O.[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0 Biotinyl MG 860555P-1MG
Empirical Formula (Hill Notation): C25H45N3O6S CAS Number: 799812-64-9 Molecular Weight: 515.71 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860555P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860555P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string OCC(O)COC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0 Coenzyme A 870712P-5MG
Empirical Formula (Hill Notation): C33H67N10O17P3S CAS Number: 799812-84-3 Molecular Weight: 1000.93 NACRES: NA.25 General description12:0 Coenzyme A is an acyl CoA derivative of saturated fatty acid.Biochem/physiol ActionsCoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. Acylated derivatives, for example Acetyl-CoA, are critical intermediates in many metabolic reactions ADD>, particularly fatty acid and carbohydrate metabolism.Packaging5 mL Amber Glass Screw Cap Vial (870712P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (870712P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
12:0 DG
Empirical Formula (Hill Notation): C27H52O5 CAS Number: 60562-15-4 Molecular Weight: 456.70
Кат. номер 800812P-200MG 800812P-10MG General descriptionsn-1,2-diacylglycerols comprise short saturated acyl side chains (C4-C10) and 12:0 DG is also called 1,2-dilauroyl-sn-glycerol.Application12:0 DG has been used as an internal standard for spiking serum samples for liquid chromatography–mass spectrometry analysis. It may be used as an internal standard for spiking RAW 264.7 cells for mass spectroscopy studies and in reverse phase liquid chromatography coupled mass spectrometer for lipidomics studies of human plasma and serum samples.Biochem/physiol Actions1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.Packaging5 mL Amber Glass Screw Cap Vial (800812P-200mg)
5 mL Amber Glass Screw Cap Vial (800812P-10mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (800812P-10mg), pkg of 1 x 200 mg (800812P-200mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C InChI 1S/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3/t25-/m0/s1 InChI key OQQOAWVKVDAJOI-VWLOTQADSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 Diether PC 999994P-10MG
Empirical Formula (Hill Notation): C32H68NO6P CAS Number: 72593-72-7 Molecular Weight: 593.86 NACRES: NA.25 General description12:0 Diether PC (phosphocholine) is a glycerophospholipid having choline as the alcohol moiety, attached to the phosphate group. It has two dodecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds.Application12:0 Diether PC or 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine might be used in small micelles to study the interaction of peptides with model membranes by nuclear magnetic resonance (NMR) experiments.Biochem/physiol Actions12:0 Diether PC (phosphocholine) is useful in bicelles formation. Bicelles are suitable to be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. It is found to be a simpler membrane model and is highly compatible with nuclear magnetic resonance (NMR).Packaging5 mL Amber Glass Screw Cap Vial (999994P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (999994P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCC)COCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0 Diether PC 999994C-10MG
Empirical Formula (Hill Notation): C32H68NO6P CAS Number: 72593-72-7 Molecular Weight: 593.86 NACRES: NA.25 General description12:0 Diether PC (phosphocholine) is a glycerophospholipid having two dodecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.Application12:0 Diether PC or 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine might be used in small micelles for nuclear magnetic resonance (NMR) experiments to study the interaction of peptide with model membranes.Biochem/physiol Actions12:0 Diether PC (phosphocholine) is found to be a simpler membrane model and is highly compatible with nuclear magnetic resonance (NMR). It is useful in bicelles formation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.Packaging5 mL Clear Glass Sealed Ampule (999994C-10mg)Параметрыpackaging pkg of 1 x 1 mL (999994C-10mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (999994C-10mg) shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCC)COCCCCCCCCCCCC)=O
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
12:0 Dihydro SM (d18:0/12:0)
Empirical Formula (Hill Notation): C35H73N2O6P CAS Number: 474923-31-4 Molecular Weight: 648.94 NACRES: NA.25
Кат. номер 860683P-5MG 860683P-10MG General descriptionN-lauroyl-D-erythro-sphinganylphosphorylcholine (12:0 Dihydro SM (d18:0/12:0)) is a synthetic sphingomyelin (SM). Dihydro SM contains sphinganine as a long chain base.ApplicationN-lauroyl-D-erythro-sphinganylphosphorylcholine (12:0 Dihydro SM (d18:0/12:0)) has been used as an internal standard in electrospray ionization mass spectrometry (ESI-MS) for quantification of lipids extracted from erythrocyte samples.Packaging5 mL Amber Glass Screw Cap Vial (860683P-10mg)
5 mL Amber Glass Screw Cap Vial (860683P-5mg)Параметрыform powder packaging pkg of 1 x 10 mg (860683P-10mg), pkg of 1 x 5 mg (860683P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@](CCCCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0 EPC (Cl Salt) 890700C-10MG
Empirical Formula (Hill Notation): C34H69NO8PCl CAS Number: 474945-22-7 Molecular Weight: 686.34 NACRES: NA.25 General description1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is a cationic phospholipid. 12:0 EPC is a short chain analog of dioleoyl ethylphosphatidylcholine. O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.Application1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC (Cl Salt)) is suitable:- for use in lipoplex
- to study its effect on transfection of human umbilical artery endothelial cells (HUAEC)
- in liposome preparation
- in lipid mixtures to study its cubic phases of formation, stability and phase transitions
Biochem/physiol ActionsChemically synthesized cationic lipids are applicable as non-viral gene carriers. Variation in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency. 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is preferred for transfection of cultured primary endothelial cells. 12:0 EPC forms lamellar lipoplexes possessing high to superior transfection activity.Packaging5 mL Clear Glass Sealed Ampule (890700C-10mg)Параметрыpackaging pkg of 1 x 1 mL (890700C-10mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (890700C-10mg) shipped in dry ice storage temp. 20°C SMILES string O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)OCC.[Cl-]
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
12:0 EPC (Cl Salt) 890700P-10MG
Empirical Formula (Hill Notation): C34H69NO8PCl CAS Number: 474945-22-7 Molecular Weight: 686.34 NACRES: NA.25 General description1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is a cationic phospholipid. 12:0 EPC is a short-chain analog of dioleoyl ethylphosphatidylcholine. O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.Application1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC (Cl Salt)) is suitable for use in lipoplex preparation and to study the lipoplex transfection activity. It might also be used in lipid mixtures to study its cubic phases of formation, stability and phase transitions.Biochem/physiol Actions1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is preferred for transfection of cultured primary endothelial cells. 12:0 EPC forms lamellar lipoplexes possessing high to superior transfection activity. Chemically synthesized cationic lipids are applicable as non-viral gene carriers. Variation in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency.Packaging5 mL Clear Glass Sealed Ampule (890700P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (890700P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)OCC.[Cl-]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0 Lyso NBD PC
Empirical Formula (Hill Notation): C26H44N5O10P CAS Number: 1246303-00-3 Molecular Weight: 617.63 NACRES: NA.25
Кат. номер 810128P-5MG 810128P-1MG Application12:0 Lyso NBD PC has been used in the NBD-LPC (7-nitrobenz-2-oxa-1,3-diazol-4-yl - Lysophosphatidylcholine) uptake assays where the fluorescence intensity of the NBD-LPC signal can be measured. It may also be used as a substrate to measure the enzymatic activity of recombinant human lysophosphatidylcholine acyltransferase 3 (rhLPCAT3).Packaging5 mL Amber Screw Cap Bottle (810128P-1mg)
5 mL Amber Screw Cap Bottle (810128P-5mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 1 mg (810128P-1mg), pkg of 5 x 1 mg (810128P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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12:0 Lyso PC 855475C-25MG
Empirical Formula (Hill Notation): C20H42NO7P CAS Number: 20559-18-6 Molecular Weight: 439.52 NACRES: NA.25 Application12:0 Lyso PC may be used to reversibly block envelope glycoprotein (Env)-mediated fusion in various cell lines. It may also be used in determining bubble local velocity profile.Packaging5 mL Clear Glass Sealed Ampule (855475C-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) packaging pkg of 1 x 2.5 mL (855475C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (855475C-25mg) shipped in dry ice storage temp. 20°C InChI 1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1 InChI key BWKILASWCLJPBO-LJQANCHMSA-N
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
12:0 Lyso PC
Empirical Formula (Hill Notation): C20H42NO7P CAS Number: 20559-18-6 Molecular Weight: 439.52 NACRES: NA.25
Кат. номер 855475P-200MG 855475P-500MG 855475P-25MG General descriptionLyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head. Lysophosphatidylcholine (Lyso-PC) is a component of blood plasma, vascular tissue and lipoproteins.Application12:0 Lyso PC has been used to study its neuritogenic activity and the applications of exogenous lipids.Biochem/physiol ActionsLysophosphatidylcholine (LPC) alters various functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.Packaging20 mL Clear Glass Screw Cap Vial (855475P-500mg)
5 mL Amber Glass Screw Cap Vial (855475P-200mg)
5 mL Amber Glass Screw Cap Vial (855475P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 200 mg (855475P-200mg), pkg of 1 x 25 mg (855475P-25mg), pkg of 1 x 500 mg (855475P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O InChI 1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1 InChI key BWKILASWCLJPBO-LJQANCHMSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 N-Biotinyl Fatty Acid 860557P-5MG
Empirical Formula (Hill Notation): C22H39N3O4S CAS Number: 135447-73-3 Molecular Weight: 441.63 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860557P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860557P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@]1(CCCCC(NCCCCCCCCCCCC(O)=O)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
12:0 N-Biotinyl fatty acid, NHS 860757P-1MG
Empirical Formula (Hill Notation): C26H42N4O6S CAS Number: 216453-50-8 Molecular Weight: 538.70 NACRES: NA.25 Packaging2 mL Amber Serum Vial with Stopper and Crimp CapПараметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860757P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@]1(CCCCC(NCCCCCCCCCCCC(ON2C(CCC2=O)=O)=O)=O)SC[C@@]3([H])[C@]1([H])NC(N3)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 PA
Empirical Formula (Hill Notation): C27H52O8PNa CAS Number: 108321-06-8 Molecular Weight: 558.66 NACRES: NA.25
Кат. номер 840635P-25MG 840635P-200MG General description12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.Application12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis. It may be used as a lipid standard:- for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
- for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry
- in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis
Biochem/physiol ActionsPhosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.Packaging5 mL Amber Glass Screw Cap Vial (840635P-25mg)
5 mL Amber Glass Screw Cap Vial (840635P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (840635P-200mg), pkg of 1 x 25 mg (840635P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 PC (DLPC)
Empirical Formula (Hill Notation): C32H64NO8P CAS Number: 18194-25-7 Molecular Weight: 621.83 NACRES: NA.25
Кат. номер 850335P-200MG 850335P-500MG 850335P-1G 850335P-25MG General descriptionPhosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application12:0 PC (DLPC) is suitable to use as a phospholipid (PL) standard to quantify phosphatidylcholine (PC) by electrospray ionization mass spectrometry (ESI-MS).Biochem/physiol ActionsPhosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.Packaging5 mL Amber Glass Screw Cap Vial (850335P-200mg)
20 mL Clear Glass Screw Cap Vial (850335P-1g)
20 mL Clear Glass Screw Cap Vial (850335P-500mg)
5 mL Amber Glass Screw Cap Vial (850335P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 g (850335P-1g), pkg of 1 x 200 mg (850335P-200mg), pkg of 1 x 25 mg (850335P-25mg), pkg of 1 x 500 mg (850335P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O InChI 1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1 InChI key IJFVSSZAOYLHEE-PMERELPUSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 PE
Empirical Formula (Hill Notation): C29H58NO8P CAS Number: 59752-57-7 Molecular Weight: 579.75 NACRES: NA.25
Кат. номер 850702P-200MG 850702P-1G 850702P-25MG General descriptionPhosphatidylethanolamine (PE) is one of the widely distributed glycerophospholipid in eukaryotic cells. 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE/DLPE) possess an ammonium head group (RNH3+) and has alkyl chains made of 11 carbon atoms.Application1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE):- has been used as a lipid standard in the optimization of the liquid chromatographymass spectrometry (LC-MS) method conditions
- may be used as a phospholipid (PL) standard to quantify phosphatidylethanolamine (PE) from plant lipids
- may be used to prepare anionic liposomes
- may be used to prepare binary giant unilamellar vesicles (GUVs)
Biochem/physiol ActionsPhosphatidylethanolamine (PE) plays a vital role in the structure and function of eukaryotic membranes.Packaging20 mL Clear Glass Screw Cap Vial (850702P-1g)
5 mL Amber Glass Screw Cap Vial (850702P-25mg)
5 mL Amber Glass Screw Cap Vial (850702P-200mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 g (850702P-1g), pkg of 1 x 200 mg (850702P-200mg), pkg of 1 x 25 mg (850702P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O InChI 1S/C29H58NO8P/c1-3-5-7-9-11-13-15-17-19-21-28(31)35-25-27(26-37-39(33,34)36-24-23-30)38-29(32)22-20-18-16-14-12-10-8-6-4-2/h27H,3-26,30H2,1-2H3,(H,33,34) InChI key ZLGYVWRJIZPQMM-UHFFFAOYSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 PG
Empirical Formula (Hill Notation): C30H58O10PNa CAS Number: 322647-27-8 Molecular Weight: 632.74 NACRES: NA.25
Кат. номер 840435P-25MG 840435P-200MG General descriptionPhosphatidylglycerol (PG) is one of the most important lipid, found in Gram-positive bacteria. It has odd-numbered branched-chain fatty acids as acyl chains. This phospholipid is ubiquitously present in the membranes of several organisms. 12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1-rac-glycerol)/DLPG) is an anionic phospholipid. It is an anionic analogue of the zwitterionic phospholipid, dilauroyl phosphatidylcholine (DLPC).Application12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1-rac-glycerol)) has been used in monomolecular films as representative lipid component of eukaryotic membranes to study the generality of the non-steroidal anti-inflammatory drug (NSAID)-related effect. It may also be used:- in the preparation of liposomes for PagP folding assays
- as a component in pyrene labeleld liposomes
- to construct liposome/lipid vesicle
Biochem/physiol ActionsPhosphatidylglycerol (PG) is known to participate in photosynthesis.Packaging5 mL Amber Glass Screw Cap Vial (840435P-200mg)
5 mL Amber Glass Screw Cap Vial (840435P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (840435P-200mg), pkg of 1 x 25 mg (840435P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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12:0 PS
Empirical Formula (Hill Notation): C30H57NO10PNa CAS Number: 208757-51-1 Molecular Weight: 645.74 NACRES: NA.25
Кат. номер 840038P-10MG 840038P-25MG 840038P-200MG General descriptionPhosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.Application12:0 PS may be used:- in the preparation of large unilamellar vesicles (LUVs)
- as a standard to spike replicas of extracted lipid droplets and calibration curve generation for lipidomic analysis
- to study its effects on -secretase activity
Biochem/physiol ActionsPhosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.Packaging5 mL Amber Glass Screw Cap Vial (840038P-200mg)
5 mL Amber Glass Screw Cap Vial (840038P-10mg)
5 mL Amber Glass Screw Cap Vial (840038P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (840038P-10mg), pkg of 1 x 200 mg (840038P-200mg), pkg of 1 x 25 mg (840038P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
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12:0 pyrene GM1 (synthetic) 860093P-1MG
Empirical Formula (Hill Notation): C83H130N4O31 Molecular Weight: 1679.93 Packaging5 mL Amber Glass Screw Cap Vial (860093P-1MG)Параметрыassay >99% (TLC) form powder packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
12:0 SM (d18:1/12:0)
Empirical Formula (Hill Notation): C35H71N2O6P CAS Number: 474923-21-2 Molecular Weight: 646.92 NACRES: NA.25
Кат. номер 860583P-10MG 860583P-5MG 860583P-25MG Application12:0 SM (d18:1/12:0) has been used:- as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
- as an internal standard for the quantification of serum cholesterol and triacylglycerol using liquid chromatography-mass spectrometry (LC-MS) preceded by single-step liquid-liquid extraction method
- as an internal standard for tandem mass spectrometry analysis of lipid species
Packaging5 mL Amber Glass Screw Cap Vial (860583P-25mg)
5 mL Amber Glass Screw Cap Vial (860583P-10mg)
5 mL Amber Glass Screw Cap Vial (860583P-5mg)Параметрыform powder packaging pkg of 1 x 10 mg (860583P-10mg), pkg of 1 x 25 mg (860583P-25mg), pkg of 1 x 5 mg (860583P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0(2R-OH) Ceramide 860811P-5MG
Empirical Formula (Hill Notation): C30H59NO4 CAS Number: 1246298-44-1 Molecular Weight: 497.79 NACRES: NA.25 General descriptionCeramides containing 2-hydroxy fatty acid (hFA) are found primarily in the epidermis. 12:0(2R-OH) Ceramide is a 2R hydroxylated lauric acid-containing ceramide.Biochem/physiol ActionsHydroxy fatty acid (hFA)-sphingolipids play a specific role in cell signaling. Synthesis of hFA-ceramides requires fatty acid 2-hydroxylase (FA2H). Mutations of this key enzyme are associated with the development of nervous system disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for the epidermal permeability barrier function. The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.Packaging5 mL Amber Glass Screw Cap Vial (860811P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860811P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
12:0(2S-OH) Ceramide 860812P-5MG
Empirical Formula (Hill Notation): C30H59NO4 CAS Number: 1246298-45-2 Molecular Weight: 497.79 NACRES: NA.25 General descriptionCeramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis. 12:0(2S-OH) Ceramide is a 2S hydroxylated lauric acid-containing ceramide.Biochem/physiol ActionsHydroxy fatty acid (hFA)-sphingolipids facilitate cell signaling. hFA-ceramides contribute to the permeability barrier function of the epidermis. Synthesis of hFA-ceramides are catalyzed by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. An antitumor drug, PM02734 requires hFA-ceramides in the cell membrane to exhibit its activity.Packaging5 mL Amber Glass Screw Cap Vial (860812P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860812P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену
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