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06:0-06:0 NBD PE 810100C-1MG
Empirical Formula (Hill Notation): C23H36N5O11P CAS Number: 328946-20-9 Molecular Weight: 589.53 Packaging5 mL Clear Glass Sealed Ampule (810100C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810100C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810100C-1mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
06:0-06:0 NBD PG 810167P-1MG
Empirical Formula (Hill Notation): C24H40N5O13P CAS Number: 474942-89-7 Molecular Weight: 637.57 Packaging5 mL Clear Glass Sealed Ampule (810167P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810167P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
06:0-06:0 NBD PG 810167C-1MG
Empirical Formula (Hill Notation): C24H40N5O13P CAS Number: 474942-89-7 Molecular Weight: 637.57 Packaging5 mL Clear Glass Sealed Ampule (810167C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810167C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810167C-1mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
06:0-12:0 NBD PA 810178P-1MG
Empirical Formula (Hill Notation): C27H46N5O11P CAS Number: 384833-05-0 Molecular Weight: 647.65 Packaging5 mL Clear Glass Sealed Ampule (810178P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810178P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
06:0-12:0 NBD PA 810178C-1MG
Empirical Formula (Hill Notation): C27H46N5O11P CAS Number: 384833-05-0 Molecular Weight: 647.65 Packaging5 mL Clear Glass Sealed Ampule (810178C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810178C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810178C-1mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
06:0-12:0 NBD PC 810115P-1MG
Empirical Formula (Hill Notation): C32H54N5O11P CAS Number: 328946-23-2 Molecular Weight: 715.77 Packaging5 mL Clear Glass Sealed Ampule (810115P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (810115P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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06:0-12:0 NBD PG 810168P-1MG
Empirical Formula (Hill Notation): C30H52N5O13P CAS Number: 474942-90-0 Molecular Weight: 721.73 Packaging5 mL Clear Glass Sealed Ampule (810168P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810168P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
06:0-12:0 NBD PG 810168C-1MG
Empirical Formula (Hill Notation): C30H52N5O13P CAS Number: 474942-90-0 Molecular Weight: 721.73 Packaging5 mL Clear Glass Sealed Ampule (810168C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810168C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810168C-1mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
07:0 Lyso PC 855176P-25MG
Empirical Formula (Hill Notation): C15H32NO7P CAS Number: 160118-49-0 Molecular Weight: 369.39 NACRES: NA.25 General description07:0 Lyso PC, a natural lysophosphatidylcholine (Lyso-PC), is a bioactive proinflammatory lipid, produced on pathological response. It is a component of blood plasma, vascular tissue and lipoproteins.Biochem/physiol ActionsLysophosphatidylcholine (Lyso-PC) augments the expression of genes for growth factors and cellular adhesion molecules. It is linked to inflammatory diseases and atherosclerosis.Packaging5 mL Clear Glass Sealed Ampule (855176P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855176P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
07:0 Lyso PC 855176C-25MG
Empirical Formula (Hill Notation): C15H32NO7P CAS Number: 160118-49-0 Molecular Weight: 369.39 NACRES: NA.25 General description07:0 Lyso PC is a natural lysophosphatidylcholine (Lyso-PC), which is a constituent of blood plasma, vascular tissue and lipoproteins. It is a bioactive proinflammatory lipid, synthesized on pathological response.Biochem/physiol ActionsLysophosphatidylcholine (Lyso-PC) is associated with inflammatory diseases and atherosclerosis. It stimulates the expression of genes for growth factors and cellular adhesion molecules.Packaging5 mL Clear Glass Sealed Ampule (855176C-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) packaging pkg of 1 x 2.5 mL (855176C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (855176C-25mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
07:0 PC (DHPC)
Empirical Formula (Hill Notation): C22H44NO8P CAS Number: 39036-04-9 Molecular Weight: 481.56
Кат. номер 850306P-25MG 850306P-1G 850306P-500MG 850306P-200MG General descriptionThe list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis. DHPC is an ultra pure compound.Application1,2-diheptanoyl-sn-glycero-3-phosphocholine (DHPC) has been in the extraction buffer for RNA isolation from mice cortex samples and glial cells. It has also been used for the suspension of the protein loaded anti-GFP (green fluorescent protein) beads prior to immunoprecipitation.Biochem/physiol ActionsDHPC preserves the native conformation and therefore the activity of the solubilized proteins. The three dimensional structure and activity of proteins are retained not only at the 10-15mM DHPC concentrations at which maximum solubilization usually occurs, but also over a large range of DHPC concentrations (up to 40mM). Not only is the three dimensional structure and hence the activity of most protein retained in excess DHPC, but the proteins also appear to be stable in DHPC. Such a result suggests that the direct interaction of DHPC with integral membrane proteins is weak. If the interaction of DHPC with membrane proteins is indeed weak, it follows that intrinsic membrane lipids will remain associated with the membrane proteins. Solubilization Mechanism DHPC is thought to exert a wedge-like effect on the neighboring lipids, mainly due to its bulky polar group and short hydrocarbon chains. This produces membrane destabilization at relatively low DHPC concentrations. All membranes investigated are solubilized at an identical DHPC / lipid ratio. This finding is taken as evidence that DHPC primarily interacts with the lipid bilayer and not with the membrane proteins. The principle underlying the preservation of the native protein structure is the inability of DHPC to displace intrinsic membrane lipids from integral membrane proteins.Advantages of DHPC: DHPC preserves the activity of solubilized membrane proteins. DHPC is not readily oxidized, and is stable over a wide pH range (4-10). DHPC forms micelles rather than bilayers when dispersed in water. (CMC = 1.4mM). DHPC shows a broad size distribution depending on the NaCl concentration of suspension. DHPC does not interfere with spectrophotometric measurements.Packaging20 mL Clear Glass Screw Cap Vial (850306P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (850306P-500mg)
5 mL Clear Glass Sealed Ampule (850306P-25mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850306P-1g)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 g (850306P-1g), pkg of 1 x 200 mg (850306P-200mg), pkg of 1 x 25 mg (850306P-25mg), pkg of 1 x 500 mg (850306P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCC)=O)COC(CCCCCC)=O)=O InChI 1S/C22H44NO8P/c1-6-8-10-12-14-21(24)28-18-20(31-22(25)15-13-11-9-7-2)19-30-32(26,27)29-17-16-23(3,4)5/h20H,6-19H2,1-5H3/t20-/m1/s1 InChI key RBFSPQDASPEAID-HXUWFJFHSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
08:0 Coenzyme A 870708P-5MG
Empirical Formula (Hill Notation): C29H59N10O17P3S CAS Number: 799812-82-1 Molecular Weight: 944.82 NACRES: NA.25 General description08:0 Coenzyme A, also referred as octanoyl Coenzyme A, is a medium-chain acyl CoA. It is a coenzyme A derivative of octanoic acid.Application08:0 Coenzyme A has been used as a substrate in microsomal ghrelin octanoyltransferase assay.Biochem/physiol Actions08:0 Coenzyme A acts as an intermediate in mitochondrial fatty acid β-oxidation. It hinders the activity of citrate synthase (CS) and glutamate dehydrogenase (GDH). Higher levels of octanoyl –CoA, due to reduced β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH), is observed in patients with MCADH deficiency (MCD).Packaging5 mL Amber Glass Screw Cap Vial (870708P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (870708P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 DG
Empirical Formula (Hill Notation): C19H36O5 CAS Number: 60514-48-9 Molecular Weight: 344.49 NACRES: NA.25
Кат. номер 800800O-25MG 800800O-10MG General description08:0 DG (1,2-dioctanoyl-sn-glycerol), also referred as di-C8, is a short-chain cell-permeable diacyl glycerol.
In biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane.
Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.Application08:0 DG may be used:- to study its stimulatory effect on protein kinase C (PKC) in human cell lines
- as a lipid cofactor in PKC activity assay
- in vesicular-fusion protein Sec-18 binding studies
Biochem/physiol Actions08:0 DG (1,2-dioctanoyl-sn-glycerol) mimics endogenous diacylglycerol andis a active phorbol compund. It activates protein kinase C (PKC). It binds to the epidermal growth factor (EGF) receptor similar to 4-phorbol 12-myristate 13-acetate (PMA). DiC8 elevates the phosphoserine and phosphothreonine levels. DiC8 stimulates the release of superoxide in neutrophils. It downregulates nicotinic acetylcholine receptor 1 subunit 1 (nAChR1).Packaging5 mL PTFE Vial with Screw Cap (800800O-10mg)
5 mL PTFE Vial with Screw Cap (800800O-25mg)Storage and StabilityDiacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.Other NotesEffective concentration:
Most biological responses saturate at 20 to 250 µM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.Параметрыassay >99% (TLC) packaging pkg of 1 x 10 mg (with screw cap (800800O-10mg)), pkg of 1 x 25 mg (with screw cap (800800O-25mg)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C InChI 1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1 InChI key ZQBULZYTDGUSSK-KRWDZBQOSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
08:0 DGPP 810800P-10MG
Empirical Formula (Hill Notation): C19H44N2O11P2 CAS Number: 474943-13-0 Molecular Weight: 538.51 NACRES: NA.25 General descriptionDiacylglycerol pyrophosphate (DGPP), a phospholipid that is usually seen in plants and yeast. It is formed during phosphorylation of phosphatidic acid (PA) with the help of PA kinase (PAK). It is an anionic phospholipid with a pyrophosphate group attached to diacylglycerol.
Diacylglycerol pyrophosphate (DGPP), involved in a novel signaling pathway, has been found in plants, Saccharomyces cerevisiae, and Escherichia coli and macrophage-activating factor, and suggests a potential role for this compound in triggering homeostatic cellular responses.Biological Applications: Short chain DGPP (DiC8) DiC8 DGPP is added to a test tube as a chloroform solution and the solvent is removed. Add water or buffer to the dry lipid residue followed by sonication. The solution is added to cells directly. The short chain DGPP is taken up by mammalian cells and by yeast. Long chain DGPP (DiC18:1) DiC18:1 DGPP is added to a test tube as a chloroform solution and the solvent is removed. Add 0.5% Tergitol (detergent) solution and add this to cells.Notes:Biological Application — "I am not sure how well the long chain DGPP is taken up in yeast cells, that is why we synthesized the DiC8 compound. We only use the long chain compound as a standard for TLC, HPLC and for DGPP phosphatase assays".Storage Conditions — "Store concentrated, ~25mg/ml in chloroform. Concentrations below 10mg/ml are not as stable".Personal communication, George M. Carman, Sept. 1999Biochem/physiol ActionsDiacylglycerol pyrophosphate (DGPP) can decrease the phosphatidic acid (PA) signal and can acts as a signaling lipid.Packaging5 mL Clear Glass Sealed Ampule (810800P-10mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (810800P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [O-]P(OC[C@]([H])(OC(CCCCCCC)=O)COC(CCCCCCC)=O)(OP([O-])(O)=O)=O.[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 Lyso PC 855275P-25MG
Empirical Formula (Hill Notation): C16H34NO7P CAS Number: 45287-18-1 Molecular Weight: 383.42 NACRES: NA.25 General descriptionLysophosphatidylcholine (Lyso-PC) is a constituent of blood plasma, vascular tissue and lipoproteins. It is a bioactive proinflammatory lipid, produced on pathological response.Biochem/physiol ActionsLysophosphatidylcholine (Lyso-PC) is linked to inflammatory diseases and atherosclerosis. It enhances the expression of genes for growth factors and cellular adhesion molecules.Packaging5 mL Clear Glass Sealed Ampule (855275P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855275P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 Lyso PC 855275C-25MG
Empirical Formula (Hill Notation): C16H34NO7P CAS Number: 45287-18-1 Molecular Weight: 383.42 NACRES: NA.25 Application08:0 Lyso PC may be used as a substrate for sphingomyelinase D-like protein (SicTox)in 31P nuclear magnetic resonance (31P NMR) assays. It may also be used to study the self-aggregation properties of lysophosphatidylcholines (lysoPCs).Packaging5 mL Clear Glass Sealed Ampule (855275C-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) packaging pkg of 1 x 2.5 mL (855275C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (855275C-25mg) shipped in dry ice storage temp. 20°C
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
08:0 PA
Empirical Formula (Hill Notation): C19H36O8PNa CAS Number: 321883-54-9 Molecular Weight: 446.45 NACRES: NA.25
Кат. номер 830842C-25MG 830842C-10MG General descriptionPhosphatidic acid (PA) is a diacyl-glycerophospholipid. Two fatty acids and a phosphate group are attached to a glycerol molecule with the help of covalent bond through ester linkage. PA can be synthesized by the activity of the endogenous enzyme phospholipase D. This prime glycerophospholipid is present in the biomembrane. 08:0 PA (1,2-dioctanoyl-sn-glycero-3-phosphate), a short chain PA is a cell-permeable analog of PA.Application08:0 PA has been used to induce differentiation in order to study the effects of phosphatidic acids (PAs) on the inhibition of adipogenic differentiation in 3T3-L1 preadipocytes. It may be used as a mammalian target of rapamycin (mTOR) activator in SGC-996 gall bladder carcinoma cells. It may also be used to study its effects on intracellular Ca2+ concentration ([Ca2+]i) in C6 rat glioma and L2071 mouse fibroblast cells.Biochem/physiol ActionsPhosphatidic acid (PA) serves as a precursor for phosphatidylcholine or phosphatidylserine. It plays a functional role in influencing the membrane curvature and signaling. C8-PA/08:0 PA can block its association with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNAREs) to prevent the priming activity on isolated vacuoles. It also has the ability to change the proteolytic cleavage profile of Sec18.Packaging5 mL Clear Glass Sealed Ampule (830842C-25mg)
5 mL Clear Glass Sealed Ampule (830842C-10mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (830842C-10mg), pkg of 1 x 2.5 mL (830842C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (830842C-10mg), 10 mg/mL (830842C-25mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
08:0 PC 850315C-25MG
Empirical Formula (Hill Notation): C24H48NO8P CAS Number: 19191-91-4 Molecular Weight: 509.61 NACRES: NA.25 General descriptionPhosphatidylcholine (PC), a major phospholipid is mostly found in the membrane of mammals. The headgroup of this bilayer-forming lipid carries a positively and negatively charged quaternary amine and a phosphate respectively. 08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine) is a saturated synthetic short-chain phospholipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine) has been used to form a lipid film to study its effect on P-glycoproteins (P-gps) activity/to compare its effect with TWEEN®80 and Cremophor®EL. It may be used to study its effect on the nicotinamide adenine dinucleotide (NADH): n-decylubiquinone (DBQ) activity of complex I. It may also be used as a bicellar model to study their phase behavior.Packaging5 mL Clear Glass Sealed Ampule (850315C-25mg)Legal InformationCremophor is a registered trademark of BASF SE
TWEEN is a registered trademark of Croda International PLCПараметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (850315C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (850315C-25mg) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
08:0 PC
Empirical Formula (Hill Notation): C24H48NO8P CAS Number: 19191-91-4 Molecular Weight: 509.61 NACRES: NA.25
Кат. номер 850315P-200MG 850315P-25MG General descriptionThe list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Phosphatidylcholine (PC) is one of the most important constituent of the mucosal layer of the colon. 08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) is a water soluble short alkyl chain lipid.Application08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) has been used as a substrate to study the analytical capabilities of several methods to determine water soluble phospholipids containing choline (wCh-PL) and also to study the behavior of the its analytical signal in a synthetic serum matrix (data-Trol). It may also be used as a bicellar model to study their phase behavior and to form a lipid film to study its effect on P-glycoproteins (P-gps) activity/to compare its effect with TWEEN®80 and Cremophor®EL.Biochem/physiol ActionsPhosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.Packaging20 mL Clear Glass Screw Cap Vial (850315P-200mg)
5 mL Clear Glass Sealed Ampule (850315P-25mg)Legal InformationCremophor is a registered trademark of BASF SE
TWEEN is a registered trademark of Croda International PLCПараметрыassay >99% (TLC) form powder packaging pkg of 1 x 200 mg (850315P-200mg), pkg of 1 x 25 mg (850315P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC)=O)COC(CCCCCCC)=O)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
08:0 PE
Empirical Formula (Hill Notation): C21H42NO8P CAS Number: 96760-44-0 Molecular Weight: 467.53 NACRES: NA.25
Кат. номер 850699C-10MG 850699C-25MG 850699C-500MG General descriptionPhosphoethanolamine (PE), a lipid chaperone, usually seen in the membrane leaflet is abundantly present in the mitochondria.Application08:0 PE (1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine) may be used in the preparation of liposomes for conjugating with pH sensors for live cell imaging. It may also be used in the micelles for kinetic measurements studies. It has been used as a phosphoethanolamine (PE) lipid species in the lipid collision cross section (CCS) calibration mixture.Biochem/physiol ActionsPhosphoethanolamine (PE) participates in phospholipid metabolism. It has the ability to induce nutrient starvation tolerance. PE is capable of stimulating the development of tumor. It actively participates in the production of glycosylphosphatidylinositol-anchored proteins (GPI-AP).Packaging30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850699C-500mg)
5 mL Clear Glass Sealed Ampule (850699C-25mg)
5 mL Clear Glass Sealed Ampule (850699C-10mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (850699C-10mg), pkg of 1 x 2.5 mL (850699C-25mg), pkg of 1 x 20 mL (850699C-500mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (850699C-10mg), 10 mg/mL (850699C-25mg), 25 mg/mL (850699C-500mg) shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
08:0 PG 840433P-10MG
Empirical Formula (Hill Notation): C22H42O10PNa CAS Number: 322647-21-2 Molecular Weight: 520.53 NACRES: NA.25 General descriptionPhosphatidylglycerol (PG) carries one phosphate in its headgroup and has two acyl chains, that are esterified to a glycerol. Hence it carry a negative charge.Application08:0 PG (1,2-dioctanoyl-sn-glycero-3-phospho-(1-rac-glycerol)) may be used as a short-/odd-fatty acyl chain analog to spike the lipid mixture for the quantification of a natural lipid mixture (egg PG).Biochem/physiol ActionsPhosphatidylglycerol (PG) can serve as a specific ligand for 4E10 (neutralizing antibody) in the crystal structures. 08:0 PG serves as cryoprotectant in crystallization studies.Packaging5 mL Clear Glass Sealed Ampule (840433P-10mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (840433P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 PI
Empirical Formula (Hill Notation): C25H50NO13P CAS Number: 2260795-76-2 Molecular Weight: 603.64 NACRES: NA.25
Кат. номер 850181P-500UG 850181P-100UG General descriptionPhosphatidylinositol (PI), a glycerophospholipid has a head group which carries a cyclohexanol moiety. 08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1-myo-inositol)) is a PI analog with a shorter acyl chain.Application08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1-myo-inositol)) may be used:- as a substrate for phosphatidyl-myo-inositol mannosyltransferase (PimA) to compare the effect of non-substrate phospholipids on the activity
- as a replacement for mycobacterial membranes in enzymatic assays to measure PimA activity
- as a phospholipid (PL) standard in the ion trap-time of flight (IT-TOF) system to study the fragmentation principles of unique PLs and also used as a nonendogenous PL standard for the quantitative analysis of PLs in nut samples
Biochem/physiol ActionsInositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PI) serves as a precursor of a phosphoinositides, a class of signaling lipids.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850181P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850181P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]
Safety InformationRIDADR NONH for all modes of transport Flash Point F No data available Flash Point C No data available Узнать цену -
08:0 PI(3)P
Empirical Formula (Hill Notation): C25H54N2O16P2 CAS Number: 299216-98-1 Molecular Weight: 700.65
Кат. номер 850187P-500UG 850187P-100UG General descriptionPhosphatidylinositol 3-monophosphate (PI3P) is a lipid, found abundantly in eukaryotic cells. It is also present at low level in mammalian cells.Application08:0 PI(3)P has been used in the preparation of model membrane for protein reconstitution and structural studies.Biochem/physiol ActionsPhosphatidylinositol 3-monophosphate (PI3P) participates in vesicular trafficking processes. It also plays a key role in endocytosis.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850187P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850187P-500ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850187P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850187P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
08:0 PI(3,4)P2
Empirical Formula (Hill Notation): C25H58N3O19P3 CAS Number: 852043-35-7 Molecular Weight: 797.66 NACRES: NA.25
Кат. номер 850183P-500UG 850183P-100UG General descriptionInositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.Application08:0 PI(3,4)P2 (1,2-dioctanoyl-sn-glycero-3-phospho-(1-myo-inositol-3,4-bisphosphate) (ammonium salt)) has been used in hydrogen deuterium exchange mass spectrometry (HDX-MS) to compare the dynamics of full-length wild-type (WT) sorting nexin 9 (SNX9)/used in lipid mixture for SNX9 tubulation assay. It may also be used in liposomes for nanoparticle tracking analysis.Biochem/physiol ActionsPhosphatidylinositol 3,4,-biphosphate (PI(3,4)P2) serves as a lipid second messenger.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850183P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850183P-500ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850183P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850183P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 PI(3,4,5)P3
Empirical Formula (Hill Notation): C25H62N4O22P4 CAS Number: 852043-38-0 Molecular Weight: 894.67 NACRES: NA.25
Кат. номер 850186P-500UG 850186P-100UG General descriptionInositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) is a less abundant lipid.Application08:0 PI(3,4,5)P3 may be used as a control compound for assessing phosphoinositide 3-kinase activity.Biochem/physiol ActionsPhosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3), a lipid second messenger can modulate synaptic activity.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850186P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850186P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 PI(3,5)P2
Empirical Formula (Hill Notation): C25H58N3O19P3 CAS Number: 852043-36-8 Molecular Weight: 797.66 NACRES: NA.25
Кат. номер 850184P-500UG 850184P-100UG General descriptionInositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is the least found phosphoinositides (PIs) and it accounts for approximately 0.05 to 0.1% of total cellular PI.Biochem/physiol ActionsPhosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) plays a key role in the embryonic development. It is very essential at postnatal stages. It is capable of activating ion channels on endosomes and lysosomes.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-500ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850184P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850184P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 PI(4)P
Empirical Formula (Hill Notation): C25H54N2O16P2 CAS Number: 1246303-11-6 Molecular Weight: 700.65 NACRES: NA.25
Кат. номер 850182P-500UG 850182P-100UG General descriptionInositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
08:0 PIP is a phosphoinositol phosphate (PIP). Among prokaryotes, PI is synthesized by mycobacteria and few other bacterial genera.Application08:0 PIP has been used to prepare multilamellar vesicle liposomes (MLV) for lipid binding assays. It is also suitable for use in the formation of protein-lipid tube and to examine fluorescence spectrum for analysing the PIP/sterol exchange properties of the Osh1 OSBP-related domain (ORD)Biochem/physiol Actions08:0 PIP can control ion channel activity. Phosphoinositol phosphates (PIPs) with short acyl chains, that are soluble in water can be used for reversible transport into the plasma membrane.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850182P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850182P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
08:0 PI(4,5)P2
Empirical Formula (Hill Notation): C25H58N3O19P3 CAS Number: 852043-37-9 Molecular Weight: 797.66 NACRES: NA.25
Кат. номер 850185P-500UG 850185P-100UG General descriptionAlthough PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. The dioctanoyl derivative of PI(4,5)P2 is more water soluble than its long chain counterparts.Application08:0 PI(4,5)P2 is suitable for use to identify its binding site in transient receptor potential vanilloid 4 (TRPV4 N) terminus. It has been used in in vitro binding assay to determine the binding of G-protein coupled receptor kinases (GRKs) and 2-adrenergic receptor (2AR).Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (850185P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850185P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (850185P-100ug)), pkg of 1 x 500 µg (with stopper and crimp cap (850185P-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
08:0 PS
Empirical Formula (Hill Notation): C22H41NO10PNa CAS Number: 321862-88-8 Molecular Weight: 533.53 NACRES: NA.25
Кат. номер 840031P-200MG 840031P-10MG General descriptionPhosphatidylserine (PS), an acidic phospholipid is obtained from soybeans (soy-PS), bovine cortex (BC-PS) and synthetic derivation. It is mainly seen in animals, higher plants and microorganisms. It is localized in the inner leaflet of the plasma membrane.Application08:0 PS may be used as control anionic lipid to treat Xenopus eggs to study its effects on the fertilization events. It has also been used to form mixed micelles to study or compare the micellization behavior of mixed zwitterionic/cationic solutions and cationic gemini surfactants with that of 08:0 PS.Biochem/physiol ActionsPhosphatidylserine (PS) can activate protein kinase C. It aids in removing apoptotic cells and also participates in platelet aggregation.Packaging20 mL Clear Glass Screw Cap Vial (840031P-200mg)
5 mL Clear Glass Sealed Ampule (840031P-10mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (840031P-10mg), pkg of 1 x 200 mg (840031P-200mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
09:0 Lyso PC 855276P-25MG
Empirical Formula (Hill Notation): C17H36NO7P CAS Number: 253678-66-9 Molecular Weight: 397.44 NACRES: NA.25 General description09:0 Lyso PC is a short-chain lysophosphatidylcholine (lysoPC). It is polar in nature.Application09:0 Lyso PC may be used in thin-layer chromatography (TLC) analysis for lipid extraction.Packaging5 mL Clear Glass Sealed Ampule (855276P-25mg)Параметрыassay >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC) form powder packaging pkg of 1 x 25 mg (855276P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
09:0 PC 850320C-25MG
Empirical Formula (Hill Notation): C26H52NO8P CAS Number: 27869-45-0 Molecular Weight: 537.67 NACRES: NA.25 General descriptionPhosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:- as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
- as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
- an internal standard to spike frozen aliquots of plasma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)
Biochem/physiol ActionsThe physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines (PCs). They serve as a major source for eicosanoids.Packaging5 mL Clear Glass Sealed Ampule (850320C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (850320C-25mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (850320C-25mg) shipped in dry ice storage temp. 20°C InChI 1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1 InChI key CKGVBFQDYSPMSY-XMMPIXPASA-N
Safety InformationRIDADR UN 1888 6.1 / PGIII Узнать цену -
09:0 PC 850320P-25MG
Empirical Formula (Hill Notation): C26H52NO8P CAS Number: 27869-45-0 Molecular Weight: 537.67 General descriptionPhosphatidylcholines (PCs) are amphipathic molecules, which accounts for approximately 40−50% of the total cellular phospholipids. PCs are mainly located on the outer leaflets of the biological membrane bilayer.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.Application09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:- as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
- as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
- an internal standard to spike frozen aliquots of plas ma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)
Biochem/physiol ActionsPhosphatidylcholine (PC) may participate in the signaling of neuronal differentiation.Packaging5 mL Clear Glass Sealed Ampule (850320P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 25 mg (850320P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O InChI 1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1 InChI key CKGVBFQDYSPMSY-XMMPIXPASA-N
Safety InformationRIDADR UN 2811 6.1 / PGIII WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-14:0 D5 DG 800850P-1MG
Empirical Formula (Hill Notation): C31H55D5O5 Molecular Weight: 517.84 NACRES: NA.25 General description1,3-14:0 D5 DG is a glycerol derivative wherein all CH2 and CH protons of glycerol are replaced by deuterium isotope.Packaging5 mL Amber Glass Screw Cap Vial (800850P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (800850P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-16:1 D5 DG 800853C-1MG
Empirical Formula (Hill Notation): C35H59D5O5 Molecular Weight: 569.91 Packaging5 mL Amber Glass Screw Cap Vial (800853C-1MG)Параметрыassay >99% (TLC) form solution packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids concentration 1 mg/mL in chloroform shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313 Target Organs Central nervous system WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-16:1 D5 DG 800853T-1MG
Empirical Formula (Hill Notation): C35H59D5O5 Molecular Weight: 569.91 NACRES: NA.25 General description1,3-16:1 D5 DG is a glycerol derivative wherein all CH2 and CH protons of glycerol are replaced by deuterium isotope.Packaging5 mL Amber Glass Screw Cap Vial (800853T-1mg)Параметрыform solution (1:1 toluene:methanol) packaging pkg of 1 x 1 mL (800853T-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H304 - H315 - H336 - H361d - H370 - H373 pcodes P210 - P260 - P280 - P301 + P310 + P330 - P308 + P311 - P331 - P370 + P378 - P403 + P233 Target Organs Central nervous system RIDADR UN1992 - class 3 - PG 2 - RQ - Flammable liquids, toxic, n.o.s., HI: all WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-17:0 D5 DG 800854P-1MG
Empirical Formula (Hill Notation): C37H67D5O5 Molecular Weight: 602.00 NACRES: NA.25 Application1,3-17:0 D5 DG has been used as an internal standard for lipid extraction. It has also been used for the incubation of rat tissue samples.Packaging5 mL Amber Glass Screw Cap Vial (800854P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (800854P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [2H]C(C([2H])([2H])OC(CCCCCCCCCCCCCCCC)=O)(O)C([2H])([2H])OC(CCCCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-18:0 D5 DG 800855P-1MG
Empirical Formula (Hill Notation): C39H71D5O5 Molecular Weight: 630.05 Application1,3-18:0 D5 DG has been used for the preparation of liposomes. It has also been used as an internal standard for lipid extraction.Packaging5 mL Amber Glass Screw Cap Vial (800855P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (800855P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [2H]C(C([2H])([2H])OC(CCCCCCCCCCCCCCCCC)=O)(O)C([2H])([2H])OC(CCCCCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1,3-18:1 D5 DG 800856C-1MG
Empirical Formula (Hill Notation): C39H67D5O5 Molecular Weight: 626.02 Packaging5 mL Amber Glass Screw Cap Vial (800856C-1MG)Параметрыassay >99% (TLC) form solution packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids concentration 1 mg/mL in chloroform shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313 Target Organs Central nervous system WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1-C16 Ether MG 999971P-250MG
Empirical Formula (Hill Notation): C19H40O3 CAS Number: 506-03-6 Molecular Weight: 316.52 NACRES: NA.25 General description1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) is a neutral lipid containing a saturated 16-carbon alkyl chain ether and an uncharged headgroup.Application1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) might be used to study its effect on target gene expression in HepG2 cells. It might also be used to promote plasmalogen biosynthesis in lymphoblasts derived from Barth syndrome (BTHS) patients.Biochem/physiol Actions1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) acts as a precursor for plasma plasmalogen (PI) biosynthesis. It is essential for maintaining the plasmalogen levels in cell lines.Packaging20 mL Clear Glass Screw Cap Vial (999971P-250mg)Параметрыform powder packaging pkg of 1 x 250 mg (999971P-250mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](CO)(O)COCCCCCCCCCCCCCCCC InChI 1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3 InChI key OOWQBDFWEXAXPB-UHFFFAOYSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
1-deoxy-L-threo-sphinganine-d3 860475P-500UG
Empirical Formula (Hill Notation): C18H36D3NO CAS Number: 1246298-32-7 Molecular Weight: 288.53 NACRES: NA.25 General description1-deoxy-L-threo-sphinganine-d3 is a deuteriated sphinganine.Packaging5 mL Amber Glass Screw Cap Vial (860475P-500ug)Параметрыform powder packaging pkg of 1 x 500 µg (860475P-500ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCCCC[C@@](O)([H])[C@](N)([H])C([2H])([2H])[2H]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
1-deoxysphinganine
Empirical Formula (Hill Notation): C18H39NO CAS Number: 196497-48-0 Molecular Weight: 285.51 NACRES: NA.25
Кат. номер 860493P-1MG 860493P-10MG General description1-deoxysphinganine is synthesized by the condensation of palmitic acid with alanine or glycine in the presence of enzyme serine palmitoyltransferase (SPT). It is metabolized to 1-deoxyceramides.Application1-deoxysphinganine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line. It is also suitable for use as a neurotoxic agent in human CD8+ T cells.Biochem/physiol Actions1-deoxysphinganine elicits cytotoxicity towards dorsal root ganglion (DRG) neurons by disrupting the neuronal cytoskeleton formation. High levels of 1-deoxysphinganine in diabetic patients may contribute to the reduction of pancreatic β cell functionality. In hereditary sensory and autonomic neuropathy type I, mutation in the serine palmitoyltransferase gene results in altered substrate specificity, resulting in the accumulation of 1-deoxysphinganine.Packaging5 mL Amber Glass Screw Cap Vial (860493P-1mg)
5 mL Amber Glass Screw Cap Vial (860493P-10mg)Параметрыform powder packaging pkg of 1 x 1 mg (860493P-1mg), pkg of 1 x 10 mg (860493P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string C[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
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1-deoxysphinganine-d3 860474P-500UG
Empirical Formula (Hill Notation): C18H36D3NO CAS Number: 1246298-31-6 Molecular Weight: 288.53 NACRES: NA.25 General description1-deoxysphinganine-d3 is a deuterated compound, wherein the three protons of deoxysphinganine are replaced by deuterium. 1-deoxysphinganine is an atypical sphingoid base devoid of a 1-hydroxyl group.Biochem/physiol Actions1-deoxysphinganine acts as a biomarker for Type 2 diabetes. It can function as a cytotoxic lipid for insulin producing cells. 1-deoxysphinganine might exhibit toxicity to cancerous cells.Packaging5 mL Amber Glass Screw Cap Vial (860474P-500ug)Параметрыform powder packaging pkg of 1 x 500 μg (860474P-500ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string CCCCCCCCCCCCCCC[C@](O)([H])[C@](N)([H])C([2H])([2H])[2H]
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1-deoxysphingosine
Empirical Formula (Hill Notation): C18H37NO CAS Number: 193222-34-3 Molecular Weight: 283.49 NACRES: NA.25
Кат. номер 860470P-1MG 860470P-10MG General description1-deoxysphingosine (1-deoxySO) has a (4E) double bond in its structure and is synthesized by the catabolism of 1-deoxyceramide in the presence of ceramidase enzyme. It is an unsaturated deoxy-sphingoid base.Application1-deoxysphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing of MN9D dopaminergic neuroblastoma cell line and dorsal root ganglion neurons cultures. It may also be used as a standard for quantification of spingolipids from human plasma samples by liquid chromatography electrospray ionization tandem mass spectrometry (LC−ESI−MS/MS).Biochem/physiol Actions1-deoxysphingosine levels are elevated in lymphoblasts in hereditary sensory neuropathy type 1 (HSAN1) disorder.Packaging5 mL Amber Glass Screw Cap Vial (860470P-1mg)
5 mL Amber Glass Screw Cap Vial (860470P-10mg)Параметрыform powder packaging pkg of 1 x 1 mg (860470P-1mg), pkg of 1 x 10 mg (860470P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string C[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
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1-desoxymethylsphinganine 860473P-1MG
Empirical Formula (Hill Notation): C17H37NO CAS Number: 1219484-98-6 Molecular Weight: 271.48 General description1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA.Application1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1.Biochem/physiol Actions1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons.Packaging5 mL Amber Glass Screw Cap Vial (860473P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860473P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string NC[C@]([H])(O)CCCCCCCCCCCCCCC
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1-desoxymethylsphinganine-d5 860476P-1MG
Empirical Formula (Hill Notation): C17H32D5NO CAS Number: 1246298-43-0 Molecular Weight: 276.51 NACRES: NA.25 General descriptionDesoxymethylsphinganine is a are the major sphingoid-base present in mammals.Application1-desoxymethylsphinganine-d5 may be used as an internal standard for the sphingoid analysis from plasma and tissue.Biochem/physiol ActionsMutations in the palmitoyltransferase (SPT) in hereditary sensory neuropathy type 1 (HSAN-1), due to altered substrate specificity 1-desoxymethylsphinganine and 1-deoxy-sphinganine.Packaging5 mL Amber Glass Screw Cap Vial (860476P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860476P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@](CN)([H])CCCCCCCCCCCCCC(C([2H])([2H])[2H])([2H])[2H]
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1-desoxymethylsphingosine 860477P-1MG
Empirical Formula (Hill Notation): C17H35NO CAS Number: 1246303-16-1 Molecular Weight: 269.47 NACRES: NA.25 General description1-desoxymethylsphingosine is synthesized from glycine in the presence of the enzyme serine palmitoyltransferase (SPT).Application1-desoxymethylsphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line.Biochem/physiol Actions1-desoxymethylsphingosine is less neurotoxic compared to 1-desoxysphingosine in dorsal root ganglion neuronscultures Mutations in the palmitoyltransferase (SPT) in hereditary sensory neuropathy type 1 (HSAN-1), due to altered substrate specificity 1-desoxymethylsphinganine and 1-deoxy-sphinganine which are further converted to -deoxy(methyl)-ceramide and 1-deoxy(methyl)-sphingosine (1-deoxy(methyl)-SO). However, they lack the hydroxyl group essential for glycosphingolipid generation, resulting in accumulation of intermediate products.Packaging5 mL Amber Glass Screw Cap Vial (860477P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860477P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string CCCCCCCCCCCCC/C=C/[C@](O)([H])CN
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1-O-Acyl-Ceramide 860526P-5MG
Empirical Formula (Hill Notation): C53H101NO4 CAS Number: 1246303-19-4 Molecular Weight: 816.37 NACRES: NA.25 General description1-O-Acyl-Ceramide is an epidermal ceramide present in mouse and human epidermis. It comprises long chain fatty acids in 1-O-position and is synthesized in the endoplasmic reticulum-related sites.Application1-O-Acyl-Ceramide is suitable for use as a lipid standard in- high performance thin layer chromatography (HPTLC)
- in mass and nuclear magnetic resonance spectroscopy for the quantification of lipids isolated from vernix caseosa skin cream
- in liquid chromatography-tandem mass spectrometry for the quantification of 1-O-Acyl ceramides from liver samples
Biochem/physiol Actions1-O-Acyl-Ceramide functions in maintaining water barrier homeostasis. Deficiency of the glucosylceramide synthase enzyme leads to the accumulation of O-acylceramides. Treatment of human monoclonal antibody, REMD 2.59 leads to the accumulation of 1-O-acyl-ceramides in soleus muscle and depletion in liver.Packaging5 mL Amber Glass Screw Cap Vial (860526P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860526P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
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10-Doxyl Nonadecane 810590O-1MG
Empirical Formula (Hill Notation): C23H46NO2 CAS Number: 101829-05-4 Molecular Weight: 368.62 NACRES: NA.25 General descriptionQuenching of tryptophan (Trp) by 10-docylnonadecane can be used to measure Trp depth in the lipid membrane.Packaging5 mL Clear Glass Sealed Ampule (810590O-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mg (810590O-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F 235.4 °F - closed cup Flash Point C 113 °C - closed cup Узнать цену
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