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N-12:0-1-deoxysphinganine 860481P-1MG
Empirical Formula (Hill Notation): C30H61NO2 CAS Number: 1246298-40-7 Molecular Weight: 467.81 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860481P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860481P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
N-16:0 L-Serine 800740P-5MG
Empirical Formula (Hill Notation): C19H37NO4 CAS Number: 58725-46-5 Molecular Weight: 343.50 Biochem/physiol ActionsN-16:0 L-Serine serves as an antagonist for lysophosphatidic acid (LPA) receptor. It prevents platelet aggregation and chloride conductance induced by LPA.Packaging5 mL Amber Glass Screw Cap Vial (800740P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (800740P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C InChI 1S/C19H37NO4.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(22)20-17(16-21)19(23)24;/h17,21H,2-16H2,1H3,(H,20,22)(H,23,24);/q;+1/p-1/t17-;/m0./s1 InChI key XKMKJRANXQGSEK-LMOVPXPDSA-M
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N-16:0 L-Serine MeEster 800730P-5MG
Empirical Formula (Hill Notation): C20H39NO4 CAS Number: 79876-27-0 Molecular Weight: 357.53 NACRES: NA.25 General descriptionN-palmitoyl-L-serine methyl ester is an amino acid amphiphile. It is synthesized synthetically from N-succinimidyl palmitate, L-serine methyl ester hydrochloride and triethyl amine.Biochem/physiol ActionsN-palmitoyl-L-serine methyl ester hydrochloride is used for the synthesis of N-palmitoyl-O-phosphocholine serine (PPCS), which is a prime lipid biomarker in Niemann-Pick disease type C1. It is also used for preparation of amino acid based gelators for drug delivery studies.Packaging5 mL Amber Glass Screw Cap Vial (800730P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (800730P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
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N-16:0 Phytosphingosine
Empirical Formula (Hill Notation): C34H69NO4 CAS Number: 111149-09-8 Molecular Weight: 555.92 NACRES: NA.25
Кат. номер 860617P-5MG 860617P-10MG General descriptionPhytosphingosine is a biologically significant saturated long-chain sphingoid base, found in membranes of yeasts, fungi, plants and mammalian epidermis, including the stratum corneum.ApplicationN-16:0 Phytosphingosine has been used as a lipid standard in electrospray ionization (ESI)-mass spectrometry (MS)-based lipidomic analysis.Biochem/physiol ActionsPhytosphingosine plays a vital role in the defense mechanism of the skin by exhibiting anti-microbial and anti-inflammatory properties. It elicits keratinocyte differentiation and is therefore, used as an active ingredient in the cosmetic formulations. PHS helps in maintaining the structural integrity of the membranes. It also regulates cellular growth and mediates the heat stress response of yeast.Packaging5 mL Amber Glass Screw Cap Vial (860617P-5mg)
5 mL Amber Glass Screw Cap Vial (860617P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (860617P-10mg), pkg of 1 x 5 mg (860617P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO
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N-18:0 Phytosphingosine
Empirical Formula (Hill Notation): C36H73NO4 CAS Number: 475995-75-6 Molecular Weight: 583.97 NACRES: NA.25
Кат. номер 860610P-5MG 860610P-10MG General descriptionD-ribo-phytosphingosines or phytosphingosines (PHS) are biologically important long-chain bases present in various sphingolipids from yeasts, fungi, plants and mammals.ApplicationN-18:0 Phytosphingosine has been used as a standard for the analysis of lipids from epidermis and stratum corneum in mice by mass spectrometry.Biochem/physiol ActionsPhytosphingosine (PHS) exhibits bactericidal and anti-inflammatory activities. It prevents loss of moisture from the skin. In addition, PHS controls epidermal cell growth, differentiation and apoptosis.Packaging5 mL Amber Glass Screw Cap Vial (860610P-10mg)
5 mL Amber Glass Screw Cap Vial (860610P-5mg)Параметрыform powder packaging pkg of 1 x 10 mg (860610P-10mg), pkg of 1 x 5 mg (860610P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-18:1 L-Serine 800741P-5MG
Empirical Formula (Hill Notation): C21H39NO4 CAS Number: 1246302-99-7 Molecular Weight: 369.54 NACRES: NA.25 General descriptionN-18:1 L-Serine is a N-acyl amino acid. The amino acid and the fatty acid acyl moiety are covalently linked by amide bond.Biochem/physiol ActionsN-acyl amino acids are signaling molecules and N-acyl-serine is an endogenous orphan lipid mediator. N-oleoyl serine mediates energy homeostasis and bone metabolism. It also participates in the mitogenic signaling in osteoblasts and is a novel antiosteoporotic drugs.Packaging5 mL Amber Glass Screw Cap Vial (800741P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (800741P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
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N-18:1 L-Serine MeEster 800731P-5MG
Empirical Formula (Hill Notation): C22H41NO4 CAS Number: 1246302-98-6 Molecular Weight: 383.57 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (800731P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (800731P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
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N-20:4 L-Serine (ARA-S) 800742C-5MG
Empirical Formula (Hill Notation): C23H37NO4 CAS Number: 1246355-55-4 Molecular Weight: 391.54 NACRES: NA.25 General descriptionN-20:4 L-Serine (ARA-S), a unique lipoamino acid is endogenous in nature. It is localized to the brain. It has structural resemblance with anandamide, an endocannabinoid.Biochem/physiol ActionsN-20:4 L-Serine (ARA-S) is a signaling lipid that regulates neuronal-type Ca2+ channels in the brain. ARA-S is known to produce endothelium-dependent arterial vasodilatation in vitro. It is also found to exert neuroprotective action following brain injury.Packaging5 mL Clear Glass Sealed Ampule (800742C-5mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (800742C-5mg) Торговая марка Avanti Polar Lipids concentration 5 mg/mL (800742C-5mg) shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
N-20:4 L-Serine MeEster 800732C-5MG
Empirical Formula (Hill Notation): C24H39NO4 CAS Number: 288262-62-4 Molecular Weight: 405.57 NACRES: NA.25 Packaging5 mL Clear Glass Sealed Ampule (800732C-5mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (800732C-5mg) Торговая марка Avanti Polar Lipids concentration 5 mg/mL (800732C-5mg) shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
N-24:0 (2S-OH) Phytosphingosine 860925P-1MG
Empirical Formula (Hill Notation): C42H85NO5 CAS Number: 154801-34-0 Molecular Weight: 684.13 Packaging5ML Amber Glass Screw Cap Vial (860925P-1MG)Параметрыform powder packaging pkg of 1 x 1 mg (860925P-1MG) Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. −20°C SMILES string O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC([C@@H](O)CCCCCCCCCCCCCCCCCCCCCC)=O)CO
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
N-24:0 Phytosphingosine
Empirical Formula (Hill Notation): C42H85NO4 CAS Number: 34437-74-6 Molecular Weight: 668.13 NACRES: NA.25
Кат. номер 860724P-5MG 860724P-10MG General descriptionN-24:0 Phytosphingosine or N-lignoceroyl-phytosphingosine belongs to the group of phytosphingosines. Phytosphingosine. It is widely found in membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues.ApplicationN-24:0 Phytosphingosine has been used to study its influence on the organization and permeability barrier properties of model lipid membrane.Biochem/physiol ActionsLipid membranes composed of N-24:0 phytosphingosine are highly permeable for ions, small and lipophilic molecules, than those based on non-hydroxy fatty acid ceramide[NS24].Packaging5 mL Amber Glass Screw Cap Vial (860724P-10mg)
5 mL Amber Glass Screw Cap Vial (860724P-5mg)Параметрыform powder packaging pkg of 1 x 10 mg (860724P-10mg), pkg of 1 x 5 mg (860724P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)CO
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-24:0(2R-OH) Phytosphingosine
Empirical Formula (Hill Notation): C42H85NO5 CAS Number: 154801-30-6 Molecular Weight: 684.13 NACRES: NA.25
Кат. номер 860924P-5MG 860924P-10MG General descriptionN-24:0(2R-OH) Phytosphingosine, also called as N-(2-(R)-hydroxylignoceroyl)-phytosphingosine, is a sphingolipid that belongs to the group of phytoceramides. Phytosphingosine is a sphingoid base with hydroxyl group at the C4 position. It is highly found in plants and fungi. In addition, phytosphingosine is also present in mammalian epidermis, including the stratum corneum.ApplicationN-24:0(2R-OH) Phytosphingosine, also called as N-(2-(R)-hydroxylignoceroyl)-phytosphingosine may be used to study its effects in different hybrids of Zea mays.Biochem/physiol ActionsPhytosphingosine and its derivatives play a vital role in the body′s natural defense system. These lipids prevent dehydration of skin, control epidermal cell growth, differentiation and apoptosis. Phytosphingosine also exhibits anti-bactericidal and anti-inflammatory properties.Packaging5 mL Amber Glass Screw Cap Vial (860924P-5mg)
5 mL Amber Glass Screw Cap Vial (860924P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (860924P-10mg), pkg of 1 x 5 mg (860924P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC([C@H](O)CCCCCCCCCCCCCCCCCCCCCC)=O)CO
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N-arachidonoylglycine 870818M-10MG
Empirical Formula (Hill Notation): C22H35NO3 CAS Number: 179113-91-8 Molecular Weight: 361.52 NACRES: NA.25 General descriptionN-arachidonoylglycine (NAgly) is an endogenous ligand and a signaling lipid. It belongs to the eicosanoid family. NAgly is a natural ligand to activate G-protein coupled receptor, namely GPR18. It is found in rat brain and spinal cord.Biochem/physiol ActionsN-arachidonoylglycine (NAgly) exhibits analgesic effects.Packaging2 mL Amber Glass Sealed Ampule (870818M-10mg)Параметрыform methylene chloride solution packaging pkg of 1 x 1 mL (870818M-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCC(O)=O
Safety Informationpictograms GHS07,GHS08 signalword Warning hcodes H315 - H319 - H336 - H351 pcodes P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 Target Organs Central nervous system RIDADR UN 1593 6.1 / PGIII WGK Germany WGK 2 Flash Point F does not flash Flash Point C does not flash Узнать цену -
N-C12-deoxysphingosine
Empirical Formula (Hill Notation): C30H59NO2 CAS Number: 1246298-54-3 Molecular Weight: 465.79 NACRES: NA.25
Кат. номер 860455P-5MG 860455P-1MG General descriptionN-C12-deoxysphingosine, also known as 1-deoxydihydroceramide (1-deoxyDHCer) is, the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.ApplicationN-C12-deoxysphingosine has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).Packaging5 mL Amber Glass Screw Cap Vial (860455P-1mg)
5 mL Amber Glass Screw Cap Vial (860455P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860455P-1mg), pkg of 1 x 5 mg (860455P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C12-desoxymethylsphinganine 860461P-1MG
Empirical Formula (Hill Notation): C29H59NO2 CAS Number: 1246298-41-8 Molecular Weight: 453.78 General descriptionN-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.Biochem/physiol ActionsCeramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.Packaging5 mL Amber Glass Screw Cap Vial (860461P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860461P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C12-desoxymethylsphingosine 860466P-1MG
Empirical Formula (Hill Notation): C29H57NO2 CAS Number: 1246298-55-4 Molecular Weight: 451.77 NACRES: NA.25 General descriptionDesoxymethylsphingosine is an atypical deoxy-sphingoid base.ApplicationN-C12-desoxymethylsphingosine or N-lauroyl-1-desoxymethylsphingosine (m17:1/12:0) has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).Packaging5 mL Amber Glass Screw Cap Vial (860466P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860466P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C16-deoxysphinganine
Empirical Formula (Hill Notation): C34H69NO2 CAS Number: 378755-69-2 Molecular Weight: 523.92 NACRES: NA.25
Кат. номер 860462P-5MG 860462P-1MG General descriptionN-C16-deoxysphinganine Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The N-acyl group can be 16, 20 and 24 carbon chain. N-acylsphinganines (dihydroceramides) are synthesized by the acylation of sphingoid bases in the presence of ceramide synthases (CerS).
Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), this product is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-deoxyDHCer is not clearly understood at this time.Biochem/physiol ActionsN-acylsphinganines (dihydroceramides) levels are lower during ceramide synthase inhibition. They are intermediates of ceramide and dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.Packaging5 mL Amber Glass Screw Cap Vial (860462P-1mg)
5 mL Amber Glass Screw Cap Vial (860462P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860462P-1mg), pkg of 1 x 5 mg (860462P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C16-deoxysphingosine 860456P-1MG
Empirical Formula (Hill Notation): C34H67NO2 CAS Number: 1246298-56-5 Molecular Weight: 521.90 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (860456P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860456P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C16-desoxymethylsphinganine
Empirical Formula (Hill Notation): C33H67NO2 CAS Number: 1246298-42-9 Molecular Weight: 509.89 NACRES: NA.25
Кат. номер 860463P-5MG 860463P-1MG General descriptionN-C16-desoxymethylsphinganine is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of N-acylsphinganines (dihydroceramides) levels and accumulation of sphinganine. Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.Biochem/physiol ActionsDihydroceramides are also used for dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.Packaging5 mL Amber Glass Screw Cap Vial (860463P-5mg)
5 mL Amber Glass Screw Cap Vial (860463P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860463P-1mg), pkg of 1 x 5 mg (860463P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C16-desoxymethylsphingosine
Empirical Formula (Hill Notation): C33H65NO2 CAS Number: 1246298-57-6 Molecular Weight: 507.87 NACRES: NA.25
Кат. номер 860467P-1MG 860467P-5MG General descriptionDesoxymethylsphingosine is an atypical deoxy-sphingoid base.ApplicationN-C16-desoxymethylsphingosine or N-palmitoyl-1-desoxymethylsphingosine (m17:1/16:0) has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).Packaging5 mL Amber Glass Screw Cap Vial (860467P-5mg)
5 mL Amber Glass Screw Cap Vial (860467P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860467P-1mg), pkg of 1 x 5 mg (860467P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C24:1-deoxysphinganine 860464P-1MG
Empirical Formula (Hill Notation): C42H83NO2 CAS Number: 1246298-60-1 Molecular Weight: 634.11 NACRES: NA.25 General description1-deoxysphinganine is an atypical sphingoid base, which lacks a 1-hydroxyl group.ApplicationN-C24:1-deoxysphinganine or N-nervonoyl-1-deoxysphinganine (m18:0/24:1) has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).Biochem/physiol Actions1-deoxysphinganine might be toxic to cancer cells. It is a potential biomarker for type 2 diabetes. 1-deoxysphinganine acts as a cytotoxic lipid for insulin producing cells.Packaging5 mL Amber Glass Screw Cap Vial (860464P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860464P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string C[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C24:1-deoxysphingosine 860457P-1MG
Empirical Formula (Hill Notation): C42H81NO2 CAS Number: 1246298-58-7 Molecular Weight: 632.10 NACRES: NA.25 General descriptionThe sphingoid bases sphingosine is acylated with fatty acids with varying acyl-chain resulting in the synthesis of 1-deoxydihydroceramides (1-deoxyDHCers). These deoxyDHCers are further converted to 1-deoxyceramides (1-deoxysphingosine) and 1-(deoxymethyl)ceramides. They are produced by mammals.Biochem/physiol ActionsThe 1-deoxydihydroceramides are hydrophobic and interact with monolayers and giant unilamellar vesicles. They modulate cell membrane and may affect their biological functionality.Packaging5 mL Amber Glass Screw Cap Vial (860457P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (860457P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C24:1-desoxymethylsphinganine
Empirical Formula (Hill Notation): C41H81NO2 CAS Number: 1246298-61-2 Molecular Weight: 620.09 NACRES: NA.25
Кат. номер 860465P-5MG 860465P-1MG General descriptionN-C24:1-desoxymethylsphinganine Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. 1-deoxysphinganine (1-deoxySa) with N-acyl groups are referred as 1-deoxydihydroceramides and can have 16, 20 and 24 carbon chain.Packaging5 mL Amber Glass Screw Cap Vial (860465P-5mg)
5 mL Amber Glass Screw Cap Vial (860465P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860465P-1mg), pkg of 1 x 5 mg (860465P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCC/C=C/CCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-C24:1-desoxymethylsphingosine 860468P-1MG
Empirical Formula (Hill Notation): C41H79NO2 CAS Number: 1246298-59-8 Molecular Weight: 618.07 NACRES: NA.25 General descriptionCeramides are generated by the acylation of the sphingoid bases, sphingosine.Biochem/physiol ActionsDeoxydihydro ceramide (deoxyDHCer), nervonoyl (C24:1) is present in the mammals along with palmitoyl (C16) dihydroceramide. In general, deoxyDHCer modulates the cellular membrane properties and may contribute to its biological functionality.Packaging5 mL Amber Glass Screw Cap Vial (860468P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860468P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
n-decyl--D-maltoside 850521P-1G
Empirical Formula (Hill Notation): C22H42O11 CAS Number: 82494-09-5 Molecular Weight: 482.56 NACRES: NA.25 Applicationn-decyl-β-D-maltoside may be used as a detergent component in decyl maltopyranoside (DM)/lysis buffer to prevent protein aggregation during purification. It may also be used as a component of lysis buffer in serum amyloid A protein purification.Packaging20 mL Clear Glass Screw Cap Vial (850521P-1g)Параметрыassay >99% (contains <2% alpha isomer, TLC) form powder mol wt 482.56 g/mol packaging pkg of 1 x 1 g (850521P-1g) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OC[C@H]1O[C@@H](OCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
n-dodecyl--D-maltoside (DDM)
Empirical Formula (Hill Notation): C24H46O11 CAS Number: 69227-93-6 Molecular Weight: 510.62 NACRES: NA.25
Кат. номер 850520P-5G 850520P-1G 850520P-25G General descriptionDDM is the most widely used detergent for the isolation and purification of GPCRs. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.
n-dodecyl--D-maltoside (DDM) is a sugar-based surfactant.Applicationn-dodecyl--D-maltoside (DDM) has been used to solubilize mitochondrial extracts of fibroblasts to perform one-dimensional blue-native PAGE (BN-PAGE) analysis for assembled oxidative phosphorylation (OXPHOS) complexes.Biochem/physiol Actionsn-dodecyl--D-maltoside (DDM) exhibits biocompatibility and biodegradability. It serves as a facilitator of electron transfer in order to decrease the oxidation potential of 3,4-ethylenedioxythiophene (EDOT). It can also increase the solubility of EDOT in aqueous solution.Packaging20 mL Clear Glass Screw Cap Vial (850520P-1g)
125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)
30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)Параметрыassay >99% (contains <2% alpha isomer, TLC) form powder mol wt 510.62 g/mol packaging pkg of 1 x 1 g (850520P-1g), pkg of 1 x 25 g (850520P-25g), pkg of 1 x 5 g (850520P-5g) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2 InChI 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1 InChI key NLEBIOOXCVAHBD-QKMCSOCLSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
N-Dodecyl-Beta-D-Maltoside (DDM, 85%) 250520P-1G
Empirical Formula (Hill Notation): C24H46O11 CAS Number: 69227-93-6 Molecular Weight: 510.62 NACRES: NA.25 General descriptionThis product is a more cost-effective alternative to Avandecrys® DDM that can be used for membrane protein extraction and purification. DDM is the most widely used detergent for the isolation and purification of GPCRs. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded formPackaging20 mL Clear Glass Screw Cap Vial (250520P-1g)Legal InformationAvandecrys is a registered trademark of Avanti Polar Lipids, Inc.Параметрыassay >85% (contains <15% alpha isomer) form powder packaging pkg of 1 x 1 g (250520P-1g) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C InChI 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1 InChI key NLEBIOOXCVAHBD-QKMCSOCLSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
n-nonyl--D-glucoside 850510P-1G
Empirical Formula (Hill Notation): C15H30O6 CAS Number: 69984-73-2 Molecular Weight: 306.40 NACRES: NA.25 General descriptionn-nonyl--D-glucoside is a non-ionic(3) surfactant.
Nonyl glucoside is a dialyzable nonionic detergent for functional solubilization and purification of membrane proteins.Biochem/physiol Actionsn-nonyl--D-glucoside is usually preferred for membrane protein crystallization trials.Packaging20 mL Clear Glass Screw Cap Vial (850510P-1g)Параметрыassay >99% (contains <0.2% alpha isomer, TLC) form powder mol wt 306.40 g/mol packaging pkg of 1 x 1 g (850510P-1g) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OC[C@H]1O[C@@H](OCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O InChI 1S/C15H30O6/c1-2-3-4-5-6-7-8-9-20-15-14(19)13(18)12(17)11(10-16)21-15/h11-19H,2-10H2,1H3/t11-,12-,13+,14-,15-/m1/s1 InChI key QFAPUKLCALRPLH-UXXRCYHCSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
n-octyl--D-glucoside
Empirical Formula (Hill Notation): C14H28O6 CAS Number: 29836-26-8 Molecular Weight: 292.37 NACRES: NA.25
Кат. номер 850511P-5G 850511P-1G General descriptionOctyl glucoside is a dialyzable nonionic detergent for functional solubilization and purification of membrane proteins.
n-octyl--D-glucoside (OG) is a non-ionic detergent. It has a eight carbon hydrophobic tail.Applicationn-octyl--D-glucoside is suitable for use to study its self-diffusion coefficients in -cyclodextrin and -cyclodextrin solutions at 25°C.Biochem/physiol Actionsn-octyl--D-glucoside (OG) helps to extract, solubilize and denature membrane proteins. Octyl glucoside has versatile uses including: reconstituting an ion channel, solubilizing an enzyme and incorporating a protein into liposomes. Also, nonionizing detergent complexes are used in protein crystallization studies. It is mainly used in the expression and purification of recombinant protein.Packaging20 mL Clear Glass Screw Cap Vial (850511P-1g)
30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850511P-5g)Параметрыassay >99% (contains <0.2% alpha isomer, TLC) form powder mol wt 292.37 g/mol packaging pkg of 1 x 1 g (850511P-1g), pkg of 1 x 5 g (850511P-5g) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OC[C@H]1O[C@@H](OCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O InChI 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1 InChI key HEGSGKPQLMEBJL-RKQHYHRCSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
N-oleoylglycine 870819P-10MG
Empirical Formula (Hill Notation): C20H37NO3 CAS Number: 2601-90-3 Molecular Weight: 339.51 General descriptionN-oleoylglycine is an endogenous lipid containing glycine moiety in the head group. N-oleoylglycine structure contains an oleic acid, which is amide linked to glycine.ApplicationN-oleoylglycine has been used as a related endogenous compound to investigate the nature of the lipid head group required for OLCarn activity at GlyT2 (glycine transporter 2).Biochem/physiol ActionsN-oleoylglycine acts as a substrate for peptidylglycine amidating monooxygenase (PAM) for synthesis of oleoylamide. It is also involved in activation of G?protein?coupled receptor GPR132.Packaging5 mL Amber Glass Screw Cap Vial (870819P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (870819P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string CCCCCCCC/C=C\CCCCCCCC(NCC(O)=O)=O InChI 1S/C20H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)21-18-20(23)24/h9-10H,2-8,11-18H2,1H3,(H,21,22)(H,23,24)/b10-9- InChI key HPFXACZRFJDURI-KTKRTIGZSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
N-P Serine PA 800715P-1MG
Empirical Formula (Hill Notation): C19H44N3O7P CAS Number: 799268-44-3 Molecular Weight: 457.54 NACRES: NA.25 General descriptionN-palmitoyl serine phosphoric acid prevents human platelet aggregation, which is induced by 1-hexadecyl-2-lyso-sn-glycero-3-phosphate.
Lysophosphatidic acid (LPA) receptor modulators include N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid. N-palmitoyl serine phosphoric acid is a competitive inhibitor of the LPA receptor in Xenopus oocytes. However, in mammalian cells, N-palmitoyl-serine phosphoric acid may act as an agonist for the LPA receptor. LPA is a lipid mediator that acts similar to growth factors through G-protein coupled plasma membrane receptors. LPA may play a role in platelet aggregation, smooth muscle contraction, vasoactive changes, cytoskeletal reorganization and cell proliferation. N-palmitoyl serine phosphoric acid may also play a role in signal transduction in mammalian cells by increasing intracellular calcium.Packaging5 mL Amber Glass Screw Cap Vial (800715P-1mg)Preparation NoteProduct use: A range of 0.1-20 mM of N-palmitoyl serine phosphoric acid can be used for cell studies. Make a stock solution of 5 mM in DMSO and store at -20°C. Diluted N-palmitoyl serine phosphoric acid can be directly added to the study medium. An et al. dissolved N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (800715P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
N-P Tyrosine PA 800725P-1MG
Empirical Formula (Hill Notation): C25H48N3O7P CAS Number: 799268-45-4 Molecular Weight: 533.64 NACRES: NA.25 General descriptionLysophosphatidic acid (LPA) receptor modulators include N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid. N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid are competitive inhibitors of the LPA receptor in Xenopus oocytes. However, in mammalian cells, N-palmitoyl-tyrosine phosphoric acid may act as an agonist for the LPA receptor. LPA is a lipid mediator that acts similar to growth factors through G-protein coupled plasma membrane receptors. LPA may play a role in platelet aggregation, smooth muscle contraction, vasoactive changes, cytoskeletal reorganization and cell proliferation.Packaging5 mL Amber Glass Screw Cap Vial (800725P-1mg)Preparation NoteProduct use: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid can be used for cell studies. dissolved these lipids in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (800725P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
N-palmitoyl homocysteine (PHC) 870320P-25MG
Empirical Formula (Hill Notation): C20H42N2O3S CAS Number: 474942-73-9 Molecular Weight: 390.62 NACRES: NA.25 General descriptionN-palmitoyl homocysteine (PHC) is a pH sensitive head group modified lipid.ApplicationN-palmitoyl homocysteine (PHC) has been used in the synthesis of micelle-encapsulated temozolomide (TMZ) and targeted rapamycin micelles (TRaM).Biochem/physiol ActionsLiposomes containing pH-sensitive molecules facilitate site-specific drug release in response to the change of pH in the surrounding serum. They deliver drugs or gene fragments into the cytoplasm through the endocytotic pathway. Unlike plain liposomes, pH-sensitive liposomes effectively protect drugs and other encapsulated contents such as enzymes, plasmids, proteins and peptides from being potentially degraded at the lysosomal level. They have a wide range of clinical applications such as a carrier of potent drugs for cancer, pulmonary and infectious diseases, a vaccine adjuvant and a vehicle for contrasting agents during imaging. In addition, pH-sensitive liposomes also facilitate the transport of nucleic acids during gene therapy. DOPE liposomes containing PHC deliver their contents at the early endosome.Packaging5 mL Amber Glass Screw Cap Vial (870320P-25mg)Параметрыform powder packaging pkg of 1 x 25 mg (870320P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [O-]C(C(NC(CCCCCCCCCCCCCCC)=O)CCS)=O.[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
N-palmitoylglycine 870817P-10MG
Empirical Formula (Hill Notation): C18H35NO3 CAS Number: 2441-41-0 Molecular Weight: 313.48 NACRES: NA.25 General descriptionN-palmitoylglycine belongs to the family of acyl amides, which are endogenous lipids with a potential to modulate pain and inflammation. Structurally, N-palmitoylglycine (PalGly) comprises 16-carbon saturated fatty acid attached to glycine through amide linkage. It is a structural analog of phospholipid-derived N-acyl ethanolamine. N-palmitoylglycine, a saturated lipid is endogenously produced at high levels in rat skin and spinal cord.ApplicationN-palmitoylglycine has been used as an intact polar lipid (IPL) standard for determination of 15N values of nitrogen containing headgroups of IPLs using gas chromatography/combustion/isotope-ratio mass spectrometry.Biochem/physiol ActionsN-palmitoylglycine stimulates calcium influx and nitric oxide (NO) production through calcium-sensitive nitric-oxide synthase in sensory neurons. It acts as a lipid activator of G-protein-coupled receptor GPR132.Packaging5 mL Amber Glass Screw Cap Vial (870817P-10mg)Параметрыform powder packaging pkg of 1 x 10 mg (870817P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O=C(CCCCCCCCCCCCCCC)NCC(O)=O InChI 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22) InChI key KVTFEOAKFFQCCX-UHFFFAOYSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
N3C14SOBRAC 860857P-1MG
Empirical Formula (Hill Notation): C16H29BrN4O3 Molecular Weight: 405.33 Packaging5 mL Amber Glass Screw Cap Vial (860857P-1MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OC[C@@](NC(CBr)=O)([H])[C@]([H])(O)/C=C/CCCCCCCCCN=[N+]=[N-]
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
NBD 18:0 Ceramide 810210P-100UG
Empirical Formula (Hill Notation): C42H73N5O6 CAS Number: 1246303-04-7 Molecular Weight: 744.06 NACRES: NA.25 Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (810210P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (810210P-100ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
NBD 2-AG 810108O-500UG
Empirical Formula (Hill Notation): C29H40N4O7 CAS Number: 2134633-45-5 Molecular Weight: 556.65 NACRES: NA.25 General description2-[20-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]arachidonoyl] glycerol (NBD 2-AG) is an endogenous ligand for the cannabinoid CB1 and CB2 receptors generally found in the central nervous system.Biochem/physiol Actions2-AG plays vital role in many physiological processes as inflammation, food intake, stress and anxiety, locomotor activity, learning and memory, epileptogenesis and neuroprotection.Packaging5 mL PTFE Vial with Screw Cap (810108O-500ug)Параметрыassay >98% (AG (contains <15% 1-AG), TLC) packaging pkg of 1 x 500 μg (with screw cap (810108O-500ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. -65 to -96°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
NBD AA 810106C-1MG
Empirical Formula (Hill Notation): C26H34 N4O5 CAS Number: 2254005-15-5 Molecular Weight: 482.57 NACRES: NA.25 General descriptionThe endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are derived from arachidonic acid (AA). Fluorescent NBD-AA and NBD-AEA analogues are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Importantly, direct binding studies show the affinities of the fluorescent analogues are in the same range as the respective unlabeled ligands. Fluorescent endocannabinoid probes are useful for mapping the impact of various treatments, inhibitors, etc on endocannabinoid uptake and distribution in living cells.Packaging5 mL Amber Glass Screw Cap Vial/Argon/Foil Bag 810106C-1mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810106C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810106C-1mg) shipped in dry ice storage temp. −70°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 pcodes P260 - P280 - P301 + P312 + P330 - P304 + P340 + P311 - P305 + P351 + P338 - P403 + P233 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
NBD AEA 810107E-1MG
Empirical Formula (Hill Notation): C28H39 N5O5 CAS Number: 2134633-42-2 Molecular Weight: 525.64 NACRES: NA.25 General descriptionThe endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are derived from arachidonic acid (AA). Fluorescent NBD-AA and NBD-AEA analogs are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Importantly, direct binding studies show the affinities of the fluorescent analogs are in the same range as the respective unlabeled ligands. Fluorescent endocannabinoid probes are useful for mapping the impact of various treatments, inhibitors, etc on endocannabinoid uptake and distribution in living cells.ApplicationNBD AEA or 20-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] arachidonoyl ethanolamide might be used:- to covalently label nanoparticles for fluorescence imaging experiments
- to develop probes for the determination of direct binding affinities for wild-type (WT) human fatty acid binding protein 1 (FABP1 T94T) or FABP1 T94A analogous to that for NBD-stearic acid binding to WT rat FABP1.4
- in fluorescent ligand displacement assays to confirm the binding of phytocannabinoids and synthetic cannabinoids to FABP1
Packaging5 mL Amber Glass Screw Cap Vial with Foil Bag Argon overseal (810107E-1mg)Параметрыassay >95% (TLC) form ethanol solution packaging pkg of 1 x 1 mL (810107E-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (810107E-1mg) shipped in dry ice storage temp. −70°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P233 - P280 - P303 + P361 + P353 - P337 + P313 - P370 + P378 RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution WGK Germany WGK 3 Flash Point F 55.4 °F - closed cup Flash Point C 13.0 °C - closed cup Узнать цену -
NBD Lyso SM 810203P-50UG
Empirical Formula (Hill Notation): C293H51N6O8P CAS Number: 1246303-02-5 Molecular Weight: 3813.55 NACRES: NA.25 General descriptionLyso-sphingomyelin is a lysospingolipid used as a diagnostic biomarker. It allows a clear distinction between Niemann-Pick C disease (NP-C) and acid sphingomyelinase deficiency (ASMD).ApplicationNBD Lyso SM or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)-D-erythro-sphingosine-1-phosphocholine is suitable to determine the hydrolysis of sphingomyelin (SM) by RSp1609: acid sphingomyelinase-like phosphodiesterase (RsASML) protein.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (810203P-50ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 50 µg (with stopper and crimp cap (810203P-50ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
NBD Phytosphingosine
Empirical Formula (Hill Notation): C24H41N5O6 CAS Number: 2260669-58-5 Molecular Weight: 495.61 NACRES: NA.25
Кат. номер 810314P-100UG 810314P-50UG 810314P-250UG General descriptionPhytosphingosine (PHS) is one of the important constituent of phytoceramides. This sphingoid has a hydroxyl group at C-4 of the sphingoid long-chain base. PHS is a component of mammalian epidermis and is widely distributed in fungi and plants. Nitrobenzoxadiazole/7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) is a fluorescent conjugate.ApplicationNBD Phytosphingosine has been used as a substrate in ceramide synthase assays.Biochem/physiol ActionsPhytosphingosine (PHS) is capable of activating G-protein coupled receptor 120 (GPR120). Treating cultured keratinocytes (KC) with PHS can enhance the content of ceramide NP. It plays as key role in epidermal differentiation and also possesses anti-inflammatory and antimicrobial activities.Packaging5 mL Amber Glass Screw Cap Vial (810314P-100ug)
5 mL Amber Glass Screw Cap Vial (810314P-50ug)
5 mL Amber Glass Screw Cap Vial (810314P-250ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 μg (810314P-100ug), pkg of 1 x 250 μg (810314P-250ug), pkg of 1 x 50 μg (810314P-50ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
NBD Sphinganine 810206X-250UG
Empirical Formula (Hill Notation): C24H41N5O5 CAS Number: 1246303-03-6 Molecular Weight: 479.61 NACRES: NA.25 General descriptionSphinganine (dihydrosphingosine) is a common sphingoid base in phospholipids found in lesser amounts compared to sphingosine.ApplicationNBD Sphinganine or omega (7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol is suitable for the determination of the dihydrosphingosine (DHS) localization to endoplasmic reticulum for the activation of activating transcription factor 6 (ATF6) protein.Packaging5 mL PTFE Screw Cap Vial with Foil Bag Argon overseal (810206X-250ug)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810206X-250ug) Торговая марка Avanti Polar Lipids concentration 0.25 mg/mL (810206X-250ug) shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H302 - H315 - H319 - H331 - H336 - H351 - H361d - H370 - H372 pcodes P210 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P311 Target Organs Central nervous system RIDADR UN2810 - class 6.1 - PG 3 - RQ - Toxic, liquids, organic, n.o.s., HI: all WGK Germany WGK 3 Узнать цену -
NBD Sphinganine
Empirical Formula (Hill Notation): C24H41N5O5 CAS Number: 1246303-03-6 Molecular Weight: 479.61 NACRES: NA.25
Кат. номер 810206P-100UG 810206P-50UG 810206P-250UG General descriptionSphinganine, also called as dihydrosphingosine is a common sphingoid base in phospholipids.ApplicationNBD Sphinganine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol is suitable for the analysis of the dihydrosphingosine (DHS) localization to endoplasmic reticulum for the activation of activating transcription factor 6 (ATF6) protein.
NBD Sphinganine or omega (7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol is suitable for the analysis of the dihydrosphingosine (DHS) localization to endoplasmic reticulum for the activation of activating transcription factor 6 (ATF6) protein.Packaging5 mL PTFE Screw Cap Vial with Foil Bag Argon overpack (810206P-250ug)
5ML Glass Amber Screw Cap Vial (810206P-50UG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 250 µg (810206P-250ug), pkg of 1 x 50 µg (810206P-50UG) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
NBD Sphingosine 810205X-250UG
Empirical Formula (Hill Notation): C24H39N5O5 CAS Number: 799268-47-6 Molecular Weight: 477.60 NACRES: NA.25 General descriptionSphingosine is the most bioactive sphingoid with the common long chain base in sphingolipids. It is a constituent of the cell membrane. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) sphingosine is a derivative of sphingosine attached with the fluorescent probe, NBD group.ApplicationNBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol may be used:- as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine (PE)-containing liposomes
- to label sphingosine kinase 1 (SphK1) in order to determine its role in endocytic membrane trafficking
- to generate 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-ceramide C16
Biochem/physiol ActionsSphingosine serves as a precursor for ceramide. It is involved in the inhibition of protein kinase C in human platelets.Packaging5 mL Amber Glass Screw Cap Vial (810205X-250ug)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810205X-250ug) Торговая марка Avanti Polar Lipids concentration 0.25 mg/mL (810205X-250ug) shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 + H312 - H315 - H319 - H331 - H336 - H351 - H361d - H370 - H372 pcodes P260 - P280 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P311 - P403 + P233 Target Organs Central nervous system RIDADR UN1992 - class 3 - PG 2 - RQ - Flammable liquids, toxic, n.o.s., HI: all WGK Germany WGK 3 Flash Point F 125.5 °F Flash Point C > 51.95 °C Узнать цену -
NBD Sphingosine
Empirical Formula (Hill Notation): C24H39N5O5 CAS Number: 799268-47-6 Molecular Weight: 477.60 NACRES: NA.25
Кат. номер 810205P-50UG 810205P-250UG General descriptionSphingosine is the most bioactive sphingoid and a constituent of cell membrane. NBD sphingosine is a derivative of sphingosine tagged with the fluorophore, 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) group.ApplicationNBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol has been used to measure sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPK2) activity. NBD Sphingosine may be used as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine(PE)-containing liposomes and to label sphingosine kinase 1 (SphK1) to determine its role in endocytic membrane trafficking.Biochem/physiol ActionsSphingosine is the precursor of ceramide. It plays a major role as a selective inhibitor of protein kinase C.Packaging5ML Amber Glass Screw Cap Vial (810205P-50UG)
5 mL Amber Glass Screw Cap Vial (810205P-250UG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 250 µg (810205P-250ug), pkg of 1 x 50 µg (810205P-50ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
NBD Sphingosine-1-Phosphate
Empirical Formula (Hill Notation): C24H40N5O8P CAS Number: 799268-48-7 Molecular Weight: 557.58 NACRES: NA.25
Кат. номер 810207X-50UG 810207X-100UG General descriptionSphingosine-1-phosphate is a phosphorylated sphingosine analog and is polar. It is terminally labelled by fluorescent nitrobenzo-2-oxa-1,3-diazole (NBD) group. Sphingosine-1-phosphate is abundantly stored in platelets.ApplicationNBD sphingosine-1-phosphate has been used as a substrate in the detection of sphingosine-1-phosphate phosphatases (SPPase) enzymatic activity by in vitro assay.Biochem/physiol ActionsSphingosine-1-phosphate (S1P) initiates DNA synthesis. It is also involved in cell division, cell growth and platelet activation. S1P mediates cell movement, differentiation and survival. It specifically stimulates endothelial cells.Packaging5 mL Amber Glass Screw Cap Vial (810207X-50ug)
5 mL Amber Glass Screw Cap Vial (810207X-100ug)Параметрыassay >99% (TLC) packaging pkg of 1 x 1 mL (810207X-100ug), pkg of 1 x 1 mL (810207X-50ug) Торговая марка Avanti Polar Lipids concentration 0.05 mg/mL (810207X-50ug), 0.1 mg/mL (810207X-100ug) shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H331 - H312 - H315 - H319 - H336 - H351 - H361d - H370 - H372 pcodes P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 Target Organs Central nervous system RIDADR UN 1992 6.1(3) / PGII WGK Germany WGK 3 Узнать цену -
NBD-12 Cholesterol 810252P-1MG
Empirical Formula (Hill Notation): C45H70N4O5 CAS Number: 1246303-05-8 Molecular Weight: 747.06 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (810252P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810252P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
NBD-6 Cholesterol 810251P-1MG
Empirical Formula (Hill Notation): C39H58N4O5 CAS Number: 201731-19-3 Molecular Weight: 662.90 NACRES: NA.25 General descriptionNBD-6 Cholesterol is a fluorescent analog of the lipoprotein compound cholesterol, with NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) being the fluorescent group.ApplicationNBD-6 Cholesterol has been used for NBD-cholesterol binding assay, to study the binding of fluorescent NBD cholesterol in the binding pocket concerning ASTER domains.Biochem/physiol ActionsCholesterol is produced from acetyl-CoA by a complex multistep mevalonate pathway. In mammals, liver is the main site of de novo cholesterol synthesis contributing to almost 80% of total cholesterol synthesis. Cholesterol and its metabolites, along with its precursors, play important roles in cellular membrane physiology. They also have roles in reproductive biology, dietary nutrient absorption, stress responses, salt and water balance and calcium metabolism.Packaging5 mL Amber Glass Screw Cap Vial (810251P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (810251P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену
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