Fibronectin human plasma

MDL number:	MFCD00131062
eCl@ss:	42020141
NACRES:	NA.75

Кат. номер

F0895-1MG

F0895-2MG

F0895-5MG

F0895-PH

F0895-2MG-PW

F0895-5MG-PW

F0895-1MG-PW

Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. The FN1 gene mapped to human chromosome 2q35.
Fibronectin human plasma has been used in the determination of H2O2 consumption rate. It has also been used in coating the Sylgard® models for cell culture. It has also been used in cell adhesion and to directly pattern the protein onto the polymeric film.
Biochem/physiol Actions
Fibronectin 1 (FN1) participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis.
Preparation Note
This product is a 0.1% solution of fibronectin. The protein homogeneity is evaluated by immunoelectrophoresis, is endotoxin tested, and the source material was tested negative for HIV, hepatitis B and hepatitis C.
In coating culture surfaces, fibronectin should be diluted in sterile balanced sterile salt solution and coated with minimal volume. Surface should then be air dried for 45 minutes at room temp and can be stored for 2-4 weeks at 2-8°C
Analysis Note
Protein homogeneity is evaluated by immunoelectrophoresis.
Sylgard is a registered trademark of The Dow Chemical Company or an affiliated company of Dow

Quality Level	200
biological source	human plasma
sterility	sterile
product line	BioReagent
form	liquid
packaging	pkg of 1 mg","pkg of 2 mg","pkg of 5 mg
concentration	0.1% (Solution)
application(s)	cell culture | mammalian: suitable
surface coverage	15 µg/cm2
solubility	saline: 0.05 M (Tris-buffered)
UniProt accession no.	P02751,
shipped in	wet ice
storage temp.	2-8°C
Gene Information	human ... FN1(2335)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable