Albumin from human plasma SRP6516-1G

EC Number:	232-692-7
NACRES:	NA.32

Human albumin is encoded by ALB gene that is mapped to human chromosome 4q. The gene is developmentally regulated and is synthesized by the liver. The encoded protein has a molar mass of 65,000 Da and consists of a single polypeptide chain of 585 amino acids.
Albumin has been used in ion exchange chromatography to compare the albumin isolated from whole human plasma. It has been used to bind to phage clones in phage binding assay.
Biochem/physiol Actions
Human albumin is a globular unglycosylated serum protein that makes up for more than half of the total plasma or serum proteins. It functions in the maintenance of COP (cellular oncotic pressure). It binds to hydrophobic organic anions such as, bilirubin, long-chain fatty acids and haematin and some cations such as magnesium and calcium. It also serves as a secondary or tertiary carrier for steroids, vitamin D and thyroxine. It is involved in the catabolism of prostaglandins and metabolism of certain endogenous substances, such as lipids, and eicosanoids. It acts as a plasma buffer and scavenges oxygen free radicals, thus reducing the pathological effects of certain inflammatory diseases. Mutation in the gene coding for albumin leads to familial dysalbuminaemic hyperthyroidism.
Physical form
Lyophilized as a salt free solid.

biological source	human
assay	95% (SDS-PAGE)
form	lyophilized
mol wt	66 kDa
packaging	pkg of 1G
color	beige
UniProt accession no.	P02768 ,
shipped in	wet ice
storage temp.	20°C
Gene Information	human ... ALB(213)

pictograms	GHS08
signalword	Danger
hcodes	H334
pcodes	P261 - P284 - P304 + P340 + P312 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable