Zinc difluoromethanesulfinate
Empirical Formula (Hill Notation): | C2H2F4O4S2Zn |
CAS Number: | 1355729-38-2 |
Molecular Weight: | 295.55 |
MDL number: | MFCD23134675 |
PubChem Substance ID: | 329767342 |
NACRES: | NA.22 |
Кат. номер |
767840-100G |
767840-100MG |
767840-1G |
767840-10G |
767840-1KG |
Material is complexed with up to 1 equivalent of ZnCl2
Zinc difluoromethanesulfinate is a reagent widely used to incorporate difluoromethyl functionality onto biologically significant structural motifs. It is used to difluoromethylate compounds such as heteroarenes, thiols, enones, and α, βunsaturated carboxylic acids.
Zinc difluoromethanesulfinate (DFMS) is part of a zinc sulfinate toolbox developed by Phil Baran for the simple and rapid diversification of heterocycles.†
Practical and Innate Carbon-Hydrogen Functionalization of Heterocycles
DFMS is a new reagent for direct difluoromethylation of organic substrates via a radical process. This mild, operationally simple, chemoselective, and scalable difluoromethylation method is compatible with a range of nitrogen-containing heteroarene substrates of varying complexity as well as select classes of conjugated psystems and thiols.†
A New Reagent for Direct Difluoromethylation
Learn More at the Professor and Product Portal of Professor Phil S. Baran.
1, 10, 100 g in glass bottle
Frequently Asked Questions are available for this Product.
Quality Level | 100 |
assay | 95% |
reaction suitability | reaction type: Fluorinations, reagent type: catalyst reaction type: C-H Activation, reagent type: diversification reagent |
storage temp. | 2-8°C |
SMILES string | FC(F)S(=O)O[Zn]OS(=O)C(F)F |
InChI | 1S/2CH2F2O2S.Zn/c2*2-1(3)6(4)5;/h2*1H,(H,4,5);/q;;+2/p-2 |
InChI key | UGEYAPVLXKEKMP-UHFFFAOYSA-L |
pictograms | GHS07 |
signalword | Warning |
hcodes | H315 - H319 - H335 |
pcodes | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Target Organs | Respiratory system |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |